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Eliciting CD4-mimicking broadly neutralizing antibodies: new avenues towards the rational design of an HIV vaccine
Eliciting CD4-mimicking broadly neutralizing antibodies: new avenues towards the rational design of an HIV vaccine
Our research is supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Projektnummer 25902152...
Navigating Epstein–Barr virus autoimmunity: role of NK cells and T cells in multiple sclerosis
Navigating Epstein–Barr virus autoimmunity: role of NK cells and T cells in multiple sclerosis
This work was supported by grants from the National Key Research and Development Program of China (2022YFC3400900), Postdo...
Revolutionizing depression diagnosis: earwax analysis for cortisol and beyond
Revolutionizing depression diagnosis: earwax analysis for cortisol and beyond
The authors have no financial involvement with any organization or entity with a financial interest in or financial confli...
Control of Munc13-1 Activity by Autoinhibitory Interactions Involving the Variable N-terminal Region
Control of Munc13-1 Activity by Autoinhibitory Interactions Involving the Variable N-terminal Region
Neurons communicate through neurotransmitters that are released from presynaptic terminals through Ca2+-evoked synaptic ve...
Mechanisms of Translation-coupled Quality Control
Mechanisms of Translation-coupled Quality Control
Aberrant translation is a major cause of protein homeostasis disruption, leading to the accumulation of faulty proteins an...
Novel drimane-type sesquiterpenoids and nucleosides from the Helicoma septoconstrictum suppress the growth of ovarian cancer cells
Novel drimane-type sesquiterpenoids and nucleosides from the Helicoma septoconstrictum suppress the growth of ovarian cancer cells
Ovarian cancer is the most lethal form of gynecological carcinomas, presenting a grave threat to women’s health [1]. Altho...
Pre-operative levels of angiopoietin protein-like 3 (ANGPTL3) in women diagnosed with high-grade serous carcinoma of the ovary
Pre-operative levels of angiopoietin protein-like 3 (ANGPTL3) in women diagnosed with high-grade serous carcinoma of the ovary
Cancer cells need constant supplies of lipids to survive and grow. Lipid dependence has been observed in various types of ...
Liraglutide Reduces Alcohol Consumption, Anxiety, Memory Impairment, and Synapse Loss in Alcohol Dependent Mice
Liraglutide Reduces Alcohol Consumption, Anxiety, Memory Impairment, and Synapse Loss in Alcohol Dependent Mice
Glucagon-like peptide 1 (GLP-1) analogues have been commercialized for the management of type 2 diabetes. Recent studies h...
Transient Receptor Potential Channels: Multiple Modulators of Peripheral Neuropathic Pain in Several Rodent Models
Transient Receptor Potential Channels: Multiple Modulators of Peripheral Neuropathic Pain in Several Rodent Models
Neuropathic pain, a prevalent chronic condition in clinical settings, has attracted widespread societal attention. This co...
The Role of IL-6 in Neurodegenerative Disorders
The Role of IL-6 in Neurodegenerative Disorders
“Neurodegenerative disorder” is an umbrella term for a group of fatal progressive neurological illnesses chara...
The Progress of Poststroke Seizures
The Progress of Poststroke Seizures
A stroke is one of the most common fatal diseases of the nervous system, and the number of strokes per year has increased ...
Cytokines and Soluble Mediators as Architects of Tumor Microenvironment Reprogramming in Cancer Therapy
Cytokines and Soluble Mediators as Architects of Tumor Microenvironment Reprogramming in Cancer Therapy
Traditionally, cancer has been viewed primarily as a disease of unchecked cellular proliferation, with treatments predomin...
Modulation of macrophages by a phillyrin-loaded thermosensitive hydrogel promotes skin wound healing in mice
Modulation of macrophages by a phillyrin-loaded thermosensitive hydrogel promotes skin wound healing in mice
A traumatic skin injury can destroy normal skin tissue's structural and functional integrity. Superficial skin damage that...
A Cu(Ⅱ)-eluting coating through silk fibroin film on ZE21B alloy designed for in situ endotheliazation biofunction
A Cu(Ⅱ)-eluting coating through silk fibroin film on ZE21B alloy designed for in situ endotheliazation biofunction
According to the key points of China Cardiovascular Health and Disease Report 2022 [1], CVD still ranks first in the propo...
Highly efficient GPCR immobilization with enhanced fouling resistance, salt tolerance, and chromatographic performance
Highly efficient GPCR immobilization with enhanced fouling resistance, salt tolerance, and chromatographic performance
Immobilized protein-based techniques are important for many devices, which can be used for biodetection in different field...
Potential of the Blue Calm® food supplement in the treatment of alcohol withdrawal-induced anxiety in adult zebrafish (Danio rerio)
Potential of the Blue Calm® food supplement in the treatment of alcohol withdrawal-induced anxiety in adult zebrafish (Danio rerio)
Ethanol, also known as ethyl alcohol (EtOH), is a psychoactive ingredient present in various alcoholic beverages (Ngui et ...
Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models
Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models
Parkinson's disease (PD) primarily affects the substantia nigra (SN) and striatum strata, causing progressive deterioratio...