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Molecular regulation of mitophagy signaling in tumor microenvironment and its targeting for cancer therapy
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IL-27 aggravates acute hepatic injury by promoting macrophage M1 polarization to induce Caspase-11 mediated Pyroptosis in vitro and in vivo
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The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer
1 IntroductionFor decades, cancer has been the leading cause of human health and death. According to the latest statistica...
Deciphering the role of miRNA-mRNA interactions in cerebral vasospasm post intracranial hemorrhage
Highlights1. Identification of 183 DEGs and 19 DEMs.2. Construction of miRNA-mRNA network.3. Four miRNAs and two mRNAs wer...
Construction of a circadian rhythm-related gene signature for predicting the prognosis and immune infiltration of breast cancer
1 IntroductionBreast cancer is the tumor with the highest incidence among females and has seriously threatened the health ...
Defining the high-risk category of patients with cutaneous melanoma: a practical tool based on prognostic modeling
IntroductionCutaneous melanoma (CM) is a highly aggressive skin malignancy whose incidence has increased dramatically in r...
Distinct roles of Constitutive Photomorphogenesis Protein 1 homolog (COP1) in human hepatocyte models
IntroductionThe genome is predicted to encode over 600 RING (really interesting new gene) type E3 ligases that catalyze th...
Interpretability of AI race detection model in medical imaging with saliency methods
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MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing
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Lateral walking gait phase recognition for hip exoskeleton by denoising autoencoder-lstm
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Hollow mesoporous silica nanoparticles for drug formulation and delivery: Opportunities for cancer therapy
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A fluorinated prodrug strategy enhances the therapeutic index of nanoparticle-delivered hydrophilic drugs
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Platelet membrane-cloaked biomimetic nanoparticles for targeted acute lung injury therapy
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Highly sensitive quantification of carbon black in lung burden through simplified proteinase K-mediated digestion
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Acidic pH of early endosomes governs SARS-CoV-2 transport in host cells
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Kinetics insight into the roles of the N- and C-lobes of calmodulin in RyR1 channel regulation
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Harmine promotes axon regeneration through enhancing glucose metabolism
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Transmembrane Parkinson’s Disease mutation of PINK1 leads to altered mitochondrial anchoring
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