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Predicting melatonin suppression by light in humans: unifying photoreceptor‐based equivalent daylight illuminances, spectral composition, timing and duration of light exposure
Predicting melatonin suppression by light in humans: unifying photoreceptor‐based equivalent daylight illuminances, spectral composition, timing and duration of light exposure
Abstract Light-induced melatonin suppression data from 29 peer-reviewed publications was analysed by means of a machine le...
Fine‐tuning of pathogenesis‐related protein 1 (PR1) activity by the melatonin biosynthetic enzyme ASMT2 in defense response to cassava bacterial blight
Fine‐tuning of pathogenesis‐related protein 1 (PR1) activity by the melatonin biosynthetic enzyme ASMT2 in defense response to cassava bacterial blight
Abstract Melatonin is widely involved in plant disease resistance through modulation of immune responses. Pathogenesis-rel...
No association between a common type 2 diabetes risk gene variant in the melatonin receptor gene (MTNR1B) and mortality among type 2 diabetes patients
No association between a common type 2 diabetes risk gene variant in the melatonin receptor gene (MTNR1B) and mortality among type 2 diabetes patients
Abstract The minor G risk allele in the common melatonin receptor gene (MTNR1B, rs10830963) has been associated ...
The fine‐tuning of pathogenesis‐related protein 1 (PR1) activity by the melatonin biosynthetic enzyme ASMT2 in defense response to cassava bacterial blight
The fine‐tuning of pathogenesis‐related protein 1 (PR1) activity by the melatonin biosynthetic enzyme ASMT2 in defense response to cassava bacterial blight
Abstract Melatonin is widely involved in plant disease resistance through modulation of immune responses. Pathogenesis-rel...
Safety of higher doses of melatonin in adults: A systematic review and meta‐analysis
Safety of higher doses of melatonin in adults: A systematic review and meta‐analysis
Abstract Importance Melatonin is commonly used for sleep and jetlag at low doses. However, there is less documentation on ...
Melatonin induces apoptotic cell death through Bim stabilization by Sp1‐mediated OTUD1 upregulation
Melatonin induces apoptotic cell death through Bim stabilization by Sp1‐mediated OTUD1 upregulation
Abstract Melatonin, secreted by the pineal gland, regulates the circadian rhythms and also plays an oncostatic roles in ca...
Melatonin and verteporfin synergistically suppress the growth and stemness of head and neck squamous cell carcinoma through the regulation of mitochondrial dynamics
Melatonin and verteporfin synergistically suppress the growth and stemness of head and neck squamous cell carcinoma through the regulation of mitochondrial dynamics
Abstract The prevalence of head and neck squamous cell carcinoma (HNSCC) has continued to rise for decades. However, drug ...
Melatonin supplementation in the culture medium rescues impaired glucose metabolism in IVF mice offspring
Melatonin supplementation in the culture medium rescues impaired glucose metabolism in IVF mice offspring
Abstract Increasing evidence suggests that in vitro fertilization (IVF) may be associated with an increased risk of develo...
Weekly and seasonal variation in the circadian melatonin rhythm in humans: a response
Weekly and seasonal variation in the circadian melatonin rhythm in humans: a response
Abstract We read with interest the commentary by Skeldon and Dijk about our article “Weekly, seasonal and chronotyp...
Measuring morning melatonin levels with plasma melatonin ELISA kits is a poor choice on two levels
Measuring morning melatonin levels with plasma melatonin ELISA kits is a poor choice on two levels
Abstract Recently published guidelines for the Journal of Pineal Research stated that “Measuring melatonin using a ...
Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy
Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy
ABSTRACT Adopting an integrative approach, by combining studies of cardiovascular function with those at cellular and mole...
Melatonin ameliorates cognitive deficits through improving mitophagy in a mouse model of Alzheimer’s disease
Melatonin ameliorates cognitive deficits through improving mitophagy in a mouse model of Alzheimer’s disease
Abstract While melatonin is known to have protective effects in mitochondria-related diseases, aging and neurodegenerative...
The Effect of Melatonin on Glucose Tolerance, Insulin Sensitivity, and Lipid Profiles after a Late Evening Meal in Healthy Young Males
The Effect of Melatonin on Glucose Tolerance, Insulin Sensitivity, and Lipid Profiles after a Late Evening Meal in Healthy Young Males
ABSTRACT The suppression of melatonin by light at night (LAN) has been associated with a disruption of SCN function and bi...
Melatonin pretreatment alleviates the long term synaptic toxicity and dysmyelination induced by neonatal Sevoflurane exposure via MT1 receptor mediated Wnt signaling modulation
Melatonin pretreatment alleviates the long term synaptic toxicity and dysmyelination induced by neonatal Sevoflurane exposure via MT1 receptor mediated Wnt signaling modulation
Abstract Sevoflurane (Sev) is one of the most widely used pediatric anesthetics. The major concern of neonatal repeated ap...
Therapeutic potential of melatonin and melatonergic drugs on K18‐hACE2 mice infected with SARS‐CoV‐2
Therapeutic potential of melatonin and melatonergic drugs on K18‐hACE2 mice infected with SARS‐CoV‐2
ABSTRACT As the COVID-19 pandemic grows, several therapeutic candidates are being tested or undergoing clinical trials. Al...
Fetal malnutrition is associated with impairment of endogenous melatonin synthesis in pineal via hypermethylation of promoters of protein kinase C alpha and cAMP response element‐binding
Fetal malnutrition is associated with impairment of endogenous melatonin synthesis in pineal via hypermethylation of promoters of protein kinase C alpha and cAMP response element‐binding
Abstract This study investigated whether and how fetal malnutrition would influence endogenous melatonin synthesis, and wh...
Extracellular vesicles derived from melatonin‐preconditioned mesenchymal stem cells containing USP29 repair traumatic spinal cord injury by stabilizing NRF2
Extracellular vesicles derived from melatonin‐preconditioned mesenchymal stem cells containing USP29 repair traumatic spinal cord injury by stabilizing NRF2
Abstract Spinal cord injury (SCI) is a devastating trauma that leads to irreversible motor and sensory dysfunction and is,...
Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O‐GlcNAcylation of cyclin‐dependent‐like kinase 5
Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O‐GlcNAcylation of cyclin‐dependent‐like kinase 5
Abstract Melatonin helps to maintain circadian rhythm, exerts anticancer activity, and plays key roles in regulation of gl...
Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L‐formate axis
Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L‐formate axis
Abstract Metabolic remodeling is now widely recognized as a hallmark of cancer, yet its role in head and neck squamous cel...
Fetal malnutrition is associated with impairment of endogenous melatonin synthesis in pineal via hyper‐methylation of promoters of protein kinase C alpha and cAMP‐response element‐binding
Fetal malnutrition is associated with impairment of endogenous melatonin synthesis in pineal via hyper‐methylation of promoters of protein kinase C alpha and cAMP‐response element‐binding
Abstract This study investigated whether and how fetal-malnutrition would influence endogenous melatonin synthesis, and wh...
Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O‐GlcNAcylation of CDK5
Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O‐GlcNAcylation of CDK5
Abstract Melatonin helps maintain circadian rhythm, exerts anticancer activity, and plays key roles in regulation of gluco...
The potential remedy of melatonin on osteoarthritis
The potential remedy of melatonin on osteoarthritis
Abstract Osteoarthritis (OA), the most common arthritis worldwide, is a degenerative joint disease characterized by progre...
Melatonin reduces nanoplastic uptake, translocation and toxicity in wheat
Melatonin reduces nanoplastic uptake, translocation and toxicity in wheat
Abstract With increasing plastic production and consumption, large amounts of polystyrene nanoplastics are accumulated in ...
A novel melatonin‐regulated lncRNA suppresses TPA‐induced oral cancer cell motility through replenishing PRUNE2 expression
A novel melatonin‐regulated lncRNA suppresses TPA‐induced oral cancer cell motility through replenishing PRUNE2 expression
Abstract The inhibitory effect of melatonin on cancer cell dissemination is well established, yet the functional involveme...
Treatment of isolated REM‐sleep behavior disorder using melatonin as a chronobiotic
Treatment of isolated REM‐sleep behavior disorder using melatonin as a chronobiotic
ABSTRACT Melatonin is recommended as a first-line treatment in isolated REM sleep behavior disorder (iRBD), although no la...
Pan‐cancer analyses reveal genomics and clinical characteristics of the melatonergic regulators in cancer
Pan‐cancer analyses reveal genomics and clinical characteristics of the melatonergic regulators in cancer
Abstract Melatonin, an endogenous hormone, plays protective roles in cancer. In addition to regulating circadian rhythms, ...
In‐person vs. home schooling during the COVID‐19 pandemic: Differences in sleep, circadian timing, and mood in early adolescence
In‐person vs. home schooling during the COVID‐19 pandemic: Differences in sleep, circadian timing, and mood in early adolescence
Abstract During the COVID-19 pandemic, schools around the world rapidly transitioned from in-person to remote learning, pr...
Melatonin inhibits lung cancer development by reversing the Warburg effect via stimulating the SIRT3/PDH axis
Melatonin inhibits lung cancer development by reversing the Warburg effect via stimulating the SIRT3/PDH axis
Abstract Recently, the morbidity and mortality from lung cancer have continued to increase. Mitochondrial dysfunction play...
Melatonin and other indoles show antiviral activities against swine Coronaviruses in vitro at pharmacological concentrations
Melatonin and other indoles show antiviral activities against swine Coronaviruses in vitro at pharmacological concentrations
Abstract The current coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus...
Enhanced anti‐angiogenic activity of novel melatonin‐like agents
Enhanced anti‐angiogenic activity of novel melatonin‐like agents
Abstract Hypoxia-inducible factor-1 (HIF-1) plays an important role in cellular responses to hypoxia, including the transc...
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