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The enrichment of Fanconi anemia/homologous recombination pathway aberrations in ATM/ATR-mutated NSCLC was accompanied by unique molecular features and poor prognosis
The enrichment of Fanconi anemia/homologous recombination pathway aberrations in ATM/ATR-mutated NSCLC was accompanied by unique molecular features and poor prognosis
ATM and ATR are two critical factors to regulate DNA damage response (DDR), and their mutations were frequently observed i...
A comparative study on ctDNA and tumor DNA mutations in lung cancer and benign cases with a high number of CTCs and CTECs
A comparative study on ctDNA and tumor DNA mutations in lung cancer and benign cases with a high number of CTCs and CTECs
Liquid biopsy provides a non-invasive approach that enables detecting circulating tumor DNA (ctDNA) and circulating tumor ...
TP53 missense mutation reveals gain-of-function properties in small-sized KRAS transformed pancreatic ductal adenocarcinoma
TP53 missense mutation reveals gain-of-function properties in small-sized KRAS transformed pancreatic ductal adenocarcinoma
Although the molecular features of pancreatic ductal adenocarcinoma (PDAC) have been well described, the impact of detaile...
Tigecycline causes loss of cell viability mediated by mitochondrial OXPHOS and RAC1 in hepatocellular carcinoma cells
Tigecycline causes loss of cell viability mediated by mitochondrial OXPHOS and RAC1 in hepatocellular carcinoma cells
Despite recent advances in locoregional, systemic, and novel checkpoint inhibitor treatment, hepatocellular carcinoma (HCC...
A postmortem case control study of asbestos burden in lungs of malignant mesothelioma cases
A postmortem case control study of asbestos burden in lungs of malignant mesothelioma cases
Asbestos lung content is regarded as the most reliable tool for causal attribution of malignant mesothelioma (MM) to previ...
Deep-learning-based survival prediction of patients with lower limb melanoma
Deep-learning-based survival prediction of patients with lower limb melanoma
For the purpose to examine lower limb melanoma (LLM) and its long-term survival rate, we used data from the Surveillance, ...
Dynamic estimates of survival in oncocytic cell carcinoma of the thyroid
Dynamic estimates of survival in oncocytic cell carcinoma of the thyroid
Little is known about death hazard and conditional survival of oncocytic cell carcinoma of the thyroid (OCC). Patients dia...
Mitophagy genes in ovarian cancer: a comprehensive analysis for improved immunotherapy
Mitophagy genes in ovarian cancer: a comprehensive analysis for improved immunotherapy
Mitophagy is a process of selectively degrading damaged mitochondria, which has been found to be related to immunity, tumo...
Breast cancer stem cells generate immune-suppressive T regulatory cells by secreting TGFβ to evade immune-elimination
Breast cancer stem cells generate immune-suppressive T regulatory cells by secreting TGFβ to evade immune-elimination
Cancer stem cells (CSCs), being the primary contributors in tumor initiation, metastasis, and relapse, ought to have semin...
Clinical application of 192Ir High-Dose-Rate brachytherapy in metastatic lymph nodes of the neck
Clinical application of 192Ir High-Dose-Rate brachytherapy in metastatic lymph nodes of the neck
The objective of this study was to investigate the safety and effectiveness of high-dose-rate brachytherapy as a treatment...
A novel description of the supporting system of the orbicularis oculi muscle in the infraorbital area: Tear trough muscle fiber
A novel description of the supporting system of the orbicularis oculi muscle in the infraorbital area: Tear trough muscle fiber
The aim of this study was to elucidate the anatomical structures of supporting system of the infraorbital area. Forty-four...
Does caffeine supplementation improve physical performance of elite ice hockey players? A randomized, double-blind, placebo-controlled, counterbalanced, cross-over trial
Does caffeine supplementation improve physical performance of elite ice hockey players? A randomized, double-blind, placebo-controlled, counterbalanced, cross-over trial
Available online 29 November 2023Author links open overlay panel, , , , SummaryObjectivesAlthough the positive effects of ...
Functional and nonfunctional parathyroid carcinoma: two case reports and literature review
Functional and nonfunctional parathyroid carcinoma: two case reports and literature review
Parathyroid carcinoma (PC) is a rare malignant endocrine tumor. It can be divided into functional and non-functional types...
Practical Aspects of Cardiopulmonary Exercise Testing in Children
Thieme E-Books & E-Journals
Relative Match Load in Young Professional Soccer Players during Soccer-7 and Soccer-11
Thieme E-Books & E-Journals
Impact of Strength Training Intensity on Brain-derived Neurotrophic Factor
Thieme E-Books & E-Journals
Youth Injury Knowledge and Beliefs following Neuromuscular Training Warm-up Implementation in Schools
Thieme E-Books & E-Journals
A novel complement-fixing IgM antibody targeting GPC1 as a useful immunotherapeutic strategy for the treatment of pancreatic ductal adenocarcinoma
A novel complement-fixing IgM antibody targeting GPC1 as a useful immunotherapeutic strategy for the treatment of pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with a very low survival rate at 5 ...
The promoting effect and mechanism of MAD2L2 on stemness maintenance and malignant progression in glioma
The promoting effect and mechanism of MAD2L2 on stemness maintenance and malignant progression in glioma
Glioblastoma, the most common primary malignant tumor of the brain, is associated with poor prognosis. Glioblastoma cells ...
hnRNPA2B1 promotes the occurrence and progression of hepatocellular carcinoma by downregulating PCK1 mRNA via a m6A RNA methylation manner
hnRNPA2B1 promotes the occurrence and progression of hepatocellular carcinoma by downregulating PCK1 mRNA via a m6A RNA methylation manner
N6-methyladenosine (m6A) is the most prevalent RNA modification. Although hnRNPA2B1, as a reader of m6A modification, has ...
SIX1 amplification modulates stemness and tumorigenesis in breast cancer
SIX1 amplification modulates stemness and tumorigenesis in breast cancer
Sine oculis homeobox homolog 1 (SIX1) is a transcription factor that has recently been identified as a crucial regulator o...
C–C chemokine receptor 5 is essential for conventional NK cell trafficking and liver injury in a murine hepatitis virus-induced fulminant hepatic failure model
C–C chemokine receptor 5 is essential for conventional NK cell trafficking and liver injury in a murine hepatitis virus-induced fulminant hepatic failure model
Previous studies have demonstrated that natural killer (NK) cells migrated into the liver from peripheral organs and exert...
Considerations on the morphology of the thyroid ima artery
Considerations on the morphology of the thyroid ima artery
Detailed knowledge of the thyroid ima artery is essential for surgeons consequently we conducted an analysis investigating...
Two arterial variations of the hand and wrist present bilaterally (persistent median artery and superficial dorsal branch of the radial artery): ultrasound findings
Two arterial variations of the hand and wrist present bilaterally (persistent median artery and superficial dorsal branch of the radial artery): ultrasound findings
Arterial variations of the upper limb may bear high importance for many clinical procedures, including the use of flaps in...
Clinical features and risk factors for appendiceal diverticulitis: a comparative study with acute appendicitis
Clinical features and risk factors for appendiceal diverticulitis: a comparative study with acute appendicitis
Despite their similar clinical characteristics, appendiceal diverticulitis (AD) and acute appendicitis (AA) are pathologic...
Effectiveness of Lidocaine nasal drops versus placebo drops for reducing the discomfort of nasogastric tube insertion: a randomized controlled trial study
Effectiveness of Lidocaine nasal drops versus placebo drops for reducing the discomfort of nasogastric tube insertion: a randomized controlled trial study
Nasogastric tube (NGT) insertion can be painful and distressing for the patient. Lidocaine nasal drops might be effective ...
Autogenic training to influence the flexibility of the hamstring muscles and perceived stress of healthy women – A randomized controlled feasibility study
Autogenic training to influence the flexibility of the hamstring muscles and perceived stress of healthy women – A randomized controlled feasibility study
Stretching is widely used in sports and physiotherapy for improving flexibility and performance as well as lowering risk o...
Female athlete triad epidemiology among adult athletes: A systematic review
Female athlete triad epidemiology among adult athletes: A systematic review
Since the passage of Title IX in 1972, which emphasised the importance of equal opportunity for sports participation regar...
A supplementation intake proposal for high-performance elite soccer players during a match day
A supplementation intake proposal for high-performance elite soccer players during a match day
We use cookies to help provide and enhance our service and tailor content and ads. By continuing you agree to the use of c...
Un cycle de dix semaines d’étirement et de renforcement des muscles du tronc impacte l’activité équestre et diminue les douleurs lombaires des futurs cavaliers professionnels
Un cycle de dix semaines d’étirement et de renforcement des muscles du tronc impacte l’activité équestre et diminue les douleurs lombaires des futurs cavaliers professionnels
La performance d’un athlète repose sur des préparations physiques générale et spécifique à la discipline. Ces préparations...
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