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EMCV VP2 degrades IFI16 through Caspase-dependent apoptosis to evade IFI16-STING pathway
EMCV VP2 degrades IFI16 through Caspase-dependent apoptosis to evade IFI16-STING pathway
Interferon (IFN)-γ inducible protein 16 (IFI16), a key DNA sensor, triggers downstream STING-dependent type I interfe...
SARS-CoV-2 surveillance in captive animals at the belo horizonte zoo, Minas Gerais, Brazil
SARS-CoV-2 surveillance in captive animals at the belo horizonte zoo, Minas Gerais, Brazil
The pandemic caused by SARS-CoV-2 has not only affected humans but also raised concerns about its transmission to wild ani...
Comparative analysis of the epidemiological characteristics of adenovirus, rotavirus A, and coinfection in children during 2014–2023 in Guangzhou, China
Comparative analysis of the epidemiological characteristics of adenovirus, rotavirus A, and coinfection in children during 2014–2023 in Guangzhou, China
Infection is the cause of diarrhoea, and rotaviruses and adenoviruses are important pathogens in children. A retrospective...
Peripheral immune signatures associated with the risk of hepatocarcinogenesis in cirrhotic Egyptian HCV patients before and after treatment with direct-acting antivirals
Peripheral immune signatures associated with the risk of hepatocarcinogenesis in cirrhotic Egyptian HCV patients before and after treatment with direct-acting antivirals
Although direct-acting antivirals (DAAs) have revolutionized the management of chronic HCV, the debatable association with...
Altered colonic microflora and its metabolic profile in mice with acute viral myocarditis induced by coxsackievirus B3
Altered colonic microflora and its metabolic profile in mice with acute viral myocarditis induced by coxsackievirus B3
Mounting evidence suggests that the gut-heart axis is critical in the pathogenesis of cardiovascular diseases. The gut ser...
A humanized neutralizing antibody protects against human adenovirus type 7 infection in humanized desmoglein-2 and CD46 double-receptor transgenic mice
A humanized neutralizing antibody protects against human adenovirus type 7 infection in humanized desmoglein-2 and CD46 double-receptor transgenic mice
Human adenovirus type 7 (HAdV7) has become a major public health threat due to its widespread transmission, severe associa...
Complete genome characterization by nanopore sequencing of rotaviruses A, B, and C circulating on large-scale pig farms in Russia
Complete genome characterization by nanopore sequencing of rotaviruses A, B, and C circulating on large-scale pig farms in Russia
Rotaviruses are the major etiological agents of gastroenteritis and diarrheal outbreaks in plenty of mammalian species. Th...
Navigating SARS-CoV-2-related immunopathology in Crohn’s disease: from molecular mechanisms to therapeutic challenges
Navigating SARS-CoV-2-related immunopathology in Crohn’s disease: from molecular mechanisms to therapeutic challenges
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) not only posed major health and economic burdens to internati...
HBeAg-positive CHB patients with indeterminate phase associated with a high risk of significant fibrosis
HBeAg-positive CHB patients with indeterminate phase associated with a high risk of significant fibrosis
The risk of liver fibrosis in HBeAg-positive chronic hepatitis B (CHB) patients with indeterminate phase is not well chara...
Characterization of phage HZY2308 against Acinetobacter baumannii and identification of phage-resistant bacteria
Characterization of phage HZY2308 against Acinetobacter baumannii and identification of phage-resistant bacteria
Acinetobacter baumannii (AB) is a notable cause of hospital-acquired infections, with carbapenem-resistant Acinetobacter b...
Characterization and complete genome sequence of highly lytic phage active against methicillin-resistant Staphylococcus aureus (MRSA) isolated from Egypt
Characterization and complete genome sequence of highly lytic phage active against methicillin-resistant Staphylococcus aureus (MRSA) isolated from Egypt
Methicillin-Resistant Staphylococcus aureus (MRSA) is one of the most resistant bacteria to antibiotics. S. aureus is an i...
Endogenous ZAP is associated with altered Zika virus infection phenotype
Endogenous ZAP is associated with altered Zika virus infection phenotype
The zinc finger antiviral protein 1 (ZAP) has broad antiviral activity. ZAP is an interferon (IFN)-stimulated gene, which ...
The causal association between COVID-19 and ischemic stroke: a mendelian randomization study
The causal association between COVID-19 and ischemic stroke: a mendelian randomization study
Current observational data indicates that ischemic stroke (IS) affects a significant proportion of people with COVID-19. T...
Different immunogens and prime-boost vaccination strategies affect the efficacy of recombinant candidate vaccines against pathogenic orthopoxviruses
Different immunogens and prime-boost vaccination strategies affect the efficacy of recombinant candidate vaccines against pathogenic orthopoxviruses
Recombinant avipoxviruses as putative recombinant vaccines against MPXV. Different prime–boost regimens to improve i...
Pilot-scale process development for recombinant adeno-associated virus (rAAV) production based on high-density Sf9 cell culture
Pilot-scale process development for recombinant adeno-associated virus (rAAV) production based on high-density Sf9 cell culture
In recent years, gene therapy drugs have been widely marketed, and their effectiveness and potential have been confirmed. ...
Efficacy of 8-week daclatasvir-sofosbuvir regimen in chronic hepatitis C: a systematic review and meta-analysis
Efficacy of 8-week daclatasvir-sofosbuvir regimen in chronic hepatitis C: a systematic review and meta-analysis
The high rates of the sustained virologic response 12 weeks after treatment (SVR12) in real world settings provoked the ad...
Comparative study of neutralizing antibodies titers in response to different types of COVID-19 vaccines among a group of egyptian healthcare workers
Comparative study of neutralizing antibodies titers in response to different types of COVID-19 vaccines among a group of egyptian healthcare workers
Defining the protective thresholds against the severe-acute-respiratory-syndrome-related corona virus-2 pandemic ...
Detection and molecular characterization of lumpy skin disease and bovine papular stomatitis viruses in lumpy skin disease-suspected outbreaks in Tanzania
Detection and molecular characterization of lumpy skin disease and bovine papular stomatitis viruses in lumpy skin disease-suspected outbreaks in Tanzania
Lumpy Skin Disease (LSD) is endemic in sub-Saharan countries and is currently a global threat to the cattle industry. Info...
A novel neutralizing monoclonal antibody recognizes a linear antigenic epitope of the spike protein of swine acute diarrhoea syndrome coronavirus
A novel neutralizing monoclonal antibody recognizes a linear antigenic epitope of the spike protein of swine acute diarrhoea syndrome coronavirus
Swine acute diarrhoea syndrome coronavirus (SADS-CoV) causes vomiting, severe diarrhoea and death in newborn piglets. The ...
Comprehensive retrospect and future perspective on bacteriophage and cancer
Comprehensive retrospect and future perspective on bacteriophage and cancer
Researchers gradually focus on the relationship between phage and cancer. To summarize the research hotspots and trends in...
Zika virus tropism and pathogenesis: understanding clinical impacts and transmission dynamics
Zika virus tropism and pathogenesis: understanding clinical impacts and transmission dynamics
The Zika virus (ZIKV) is classified within the Flavivirus genus of the Flaviviridae family and is categorized as an arbovi...
Epidemiology and genetic diversity of human respiratory syncytial virus in Belgium between 2011 and 2019
Epidemiology and genetic diversity of human respiratory syncytial virus in Belgium between 2011 and 2019
Human respiratory syncytial virus (HRSV) is worldwide one of the leading causes of acute respiratory tract infections in y...
Asiatic acid inhibits HBV cccDNA transcription by promoting HBx degradation
Asiatic acid inhibits HBV cccDNA transcription by promoting HBx degradation
Hepatitis B virus (HBV) infection is a persistent global public health problem, and curing for chronic hepatitis B (CHB) t...
First detection of D181 genotype of infectious bronchitis in poultry flocks of Morocco
First detection of D181 genotype of infectious bronchitis in poultry flocks of Morocco
This paper reports the first pathological and molecular characterization of the novel variant of infectious bronchitis vir...
Metabolomic alterations in the plasma of patients with various clinical manifestations of COVID-19
Metabolomic alterations in the plasma of patients with various clinical manifestations of COVID-19
The metabolomic profiles of individuals with different clinical manifestations of severe acute respiratory syndrome corona...
A first report of rotavirus B from Zambian pigs leading to the discovery of a novel VP4 genotype P[9]
A first report of rotavirus B from Zambian pigs leading to the discovery of a novel VP4 genotype P[9]
Rotavirus B (RVB) causes diarrhea in humans and pigs. Although various RVB strains were identified in humans and various a...
Adapted Milwaukee protocol for rabies treatment in a Brazilian indigenous child: case report
Adapted Milwaukee protocol for rabies treatment in a Brazilian indigenous child: case report
This case report describes the treatment of a 12-year-old indigenous Brazilian girl from the Maxakali group with rabies us...
Influence of SARS-CoV-2 variants on COVID-19 epidemiological and clinical profiles: a comparative analysis of two waves of cases
Influence of SARS-CoV-2 variants on COVID-19 epidemiological and clinical profiles: a comparative analysis of two waves of cases
The COVID-19 pandemic has been the most significant health challenge of the last century. Multiple and successive waves of...
Influence of COVID-19 pandemic on prevalence and genotype distribution of HPV in cervical cancer screening population
Influence of COVID-19 pandemic on prevalence and genotype distribution of HPV in cervical cancer screening population
Human Papillomavirus (HPV) DNA screening was a crucial element in the fight against cervical cancer and had been adopted i...
Genotype of Varicella-zoster virus isolated in Jiangsu, China
Genotype of Varicella-zoster virus isolated in Jiangsu, China
To analyze the genotypes of VZV in Jiangsu province to identify vaccine strains and wild strains, providing a molecular bi...
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