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Reducing Nogo-B Improves Hepatic Fibrosis by Inhibiting BACe1-Mediated Autophagy
Reducing Nogo-B Improves Hepatic Fibrosis by Inhibiting BACe1-Mediated Autophagy
Hepatic fibrosis (HF) is a histopathological change in the process of long-term liver injury caused by cytokine secretion ...
Therapeutic Effect of Schwann Cell-Like Cells Differentiated from Human Tonsil-Derived Mesenchymal Stem Cells on Diabetic Neuropathy in db/db Mice
Therapeutic Effect of Schwann Cell-Like Cells Differentiated from Human Tonsil-Derived Mesenchymal Stem Cells on Diabetic Neuropathy in db/db Mice
Diabetic neuropathy (DN) is the most common complication of diabetes, and approximately 50% of patients with this disease ...
Human Nasal Inferior Turbinate-Derived Neural Stem Cells Improve the Niche of Substantia Nigra Par Compacta in a Parkinson’s Disease Model by Modulating Hippo Signaling
Human Nasal Inferior Turbinate-Derived Neural Stem Cells Improve the Niche of Substantia Nigra Par Compacta in a Parkinson’s Disease Model by Modulating Hippo Signaling
Parkinson’s disease (PD) is one of the most prevalent neurodegenerative diseases, following Alzheimer’s diseas...
Mesenchymal Stem Cell Spheroids: A Promising Tool for Vascularized Tissue Regeneration
Mesenchymal Stem Cell Spheroids: A Promising Tool for Vascularized Tissue Regeneration
Mesenchymal stem cells (MSCs) are undifferentiated cells that can differentiate into specific cell lineages when exposed t...
Treatment of Syringomyelia Characterized by Focal Dilatation of the Central Canal Using Mesenchymal Stem Cells and Neural Stem Cells
Treatment of Syringomyelia Characterized by Focal Dilatation of the Central Canal Using Mesenchymal Stem Cells and Neural Stem Cells
Syringomyelia is a progressive chronic disease that leads to nerve pain, sensory dissociation, and dyskinesia. Symptoms of...
Effects of Mesenchymal Stem Cells-Derived Extracellular Vesicles on Inhibition of Hepatic Fibrosis by Delivering miR-200a
Effects of Mesenchymal Stem Cells-Derived Extracellular Vesicles on Inhibition of Hepatic Fibrosis by Delivering miR-200a
Hepatic fibrosis (HF) is a common pathological feature of chronic hepatic diseases. We aimed to illuminate the significanc...
The Main Mechanisms of Mesenchymal Stem Cell-Based Treatments against COVID-19
The Main Mechanisms of Mesenchymal Stem Cell-Based Treatments against COVID-19
Coronavirus disease 2019 (COVID-19) has a clinical manifestation of hypoxic respiratory failure and acute respiratory dist...
Characterization of Gold-Enhanced Titania: Boosting Cell Proliferation and Combating Bacterial Infestation
Characterization of Gold-Enhanced Titania: Boosting Cell Proliferation and Combating Bacterial Infestation
In this study an approach was made to efficaciously synthesize gold enhanced titania nanorods by electrospinning. This stu...
Advancements in Human Embryonic Stem Cell Research: Clinical Applications and Ethical Issues
Advancements in Human Embryonic Stem Cell Research: Clinical Applications and Ethical Issues
The development and use of human embryonic stem cells (hESCs) in regenerative medicine have been revolutionary, offering s...
Effect of Gelatin Content on Degradation Behavior of PLLA/Gelatin Hybrid Membranes
Effect of Gelatin Content on Degradation Behavior of PLLA/Gelatin Hybrid Membranes
Poly(L-lactic acid) (PLLA) is a biodegradable polymer (BP) that replaces conventional petroleum-based polymers.  ...
Exosomes Derived from Mouse Breast Carcinoma Cells Facilitate Diabetic Wound Healing
Exosomes Derived from Mouse Breast Carcinoma Cells Facilitate Diabetic Wound Healing
Exosomes derived from breast cancer have been reported to play a role in promoting cell proliferation, migration, and angi...
Exploring the Cocktail Factor Approach to Generate Salivary Gland Progenitors through Co-Culture Techniques
Exploring the Cocktail Factor Approach to Generate Salivary Gland Progenitors through Co-Culture Techniques
The derivation of salivary gland (SG) progenitors from pluripotent stem cells (PSCs) presents significant potential for de...
Signal Transducer and Activator of Transcription 4-Induced Up-Regulated LINC01278 Enhances Proliferation and Invasion of Non-Small Cell Lung Cancer Cells via the MicroRNA-877-5p/Activating Transcription Factor 4 Axis
Signal Transducer and Activator of Transcription 4-Induced Up-Regulated LINC01278 Enhances Proliferation and Invasion of Non-Small Cell Lung Cancer Cells via the MicroRNA-877-5p/Activating Transcription Factor 4 Axis
The purpose of this study was to investigate the specific effects of signal transducer and activator of transcription 4 (S...
Lung Organoids: Systematic Review of Recent Advancements and its Future Perspectives
Lung Organoids: Systematic Review of Recent Advancements and its Future Perspectives
Organoids are essentially an in vitro (lab-grown) three-dimensional tissue culture system model that meticulously replicat...
Adipose Tissue-Derived Mesenchymal Stem Cell Inhibits Osteoclast Differentiation through Tumor Necrosis Factor Stimulated Gene-6
Adipose Tissue-Derived Mesenchymal Stem Cell Inhibits Osteoclast Differentiation through Tumor Necrosis Factor Stimulated Gene-6
Mesenchymal stem cells (MSCs) have been highlighted as a potent therapeutic option for conditions with excessive osteoclas...
Reconstructed Human Skin with Hypodermis Shows Essential Role of Adipose Tissue in Skin Metabolism
Reconstructed Human Skin with Hypodermis Shows Essential Role of Adipose Tissue in Skin Metabolism
Dysregulation of skin metabolism is associated with a plethora of diseases such as psoriasis and dermatitis. Until now, re...
α-Gal Nanoparticles in CNS Trauma: II. Immunomodulation Following Spinal Cord Injury (SCI) Improves Functional Outcomes
α-Gal Nanoparticles in CNS Trauma: II. Immunomodulation Following Spinal Cord Injury (SCI) Improves Functional Outcomes
Previous investigations have shown that local application of nanoparticles presenting the carbohydrate moiety galactose-&#...
Cross-Linking Methods of the Silk Protein Hydrogel in Oral and Craniomaxillofacial Tissue Regeneration
Cross-Linking Methods of the Silk Protein Hydrogel in Oral and Craniomaxillofacial Tissue Regeneration
Craniomaxillofacial tissue defects are clinical defects involving craniomaxillofacial and oral soft and hard tissues. They...
Exosomes Secreted During Myogenic Differentiation of Human Fetal Cartilage-Derived Progenitor Cells Promote Skeletal Muscle Regeneration through miR-145-5p
Exosomes Secreted During Myogenic Differentiation of Human Fetal Cartilage-Derived Progenitor Cells Promote Skeletal Muscle Regeneration through miR-145-5p
Currently, there is no apparent treatment for sarcopenia, which is characterized by diminished myoblast function. We aimed...
Define of Optimal Addition Period of Osteogenic Peptide to Accelerate the Osteogenic Differentiation of Human Pluripotent Stem Cells
Define of Optimal Addition Period of Osteogenic Peptide to Accelerate the Osteogenic Differentiation of Human Pluripotent Stem Cells
The addition of growth factiors is commonly applied to improve the osteogenic differentiation of stem cells. However, for ...
Bulk Modification with Inorganic Particles and Immobilization of Extracellular Vesicles onto PDO Composite for Facial Rejuvenation
Bulk Modification with Inorganic Particles and Immobilization of Extracellular Vesicles onto PDO Composite for Facial Rejuvenation
The skin, a vital organ protecting against microorganisms and dehydration, undergoes structural decline with aging, leadin...
Implantation of Adipose-Derived Mesenchymal Stromal Cells (ADSCs)-Lining Prosthetic Graft Promotes Vascular Regeneration in Monkeys and Pigs
Implantation of Adipose-Derived Mesenchymal Stromal Cells (ADSCs)-Lining Prosthetic Graft Promotes Vascular Regeneration in Monkeys and Pigs
Current replacement procedures for stenosis or occluded arteries using prosthetic grafts have serious limitations in clini...
Efficacy of IFN-γ-Primed Umbilical Cord-Derived Mesenchymal Stem Cells on Temporomandibular Joint Osteoarthritis
Efficacy of IFN-γ-Primed Umbilical Cord-Derived Mesenchymal Stem Cells on Temporomandibular Joint Osteoarthritis
Temporomandibular joint osteoarthritis (TMJOA) is a degenerative disease affecting the cartilage and subchondral bone, lea...
Three Dimensional Bioprinting for Hepatic Tissue Engineering: From In Vitro Models to Clinical Applications
Three Dimensional Bioprinting for Hepatic Tissue Engineering: From In Vitro Models to Clinical Applications
Fabrication of functional organs is the holy grail of tissue engineering and the possibilities of repairing a partial or c...
Long and Short-Term Effect of mTOR Regulation on Cerebral Organoid Growth and Differentiations
Long and Short-Term Effect of mTOR Regulation on Cerebral Organoid Growth and Differentiations
The mammalian target of rapamycin (mTOR) signaling is critical for the maintenance and differentiation of neurogenesis, an...
Towards Full Thickness Small Intestinal Models: Incorporation of Stromal Cells
Towards Full Thickness Small Intestinal Models: Incorporation of Stromal Cells
Since small intestine is one of the major barriers of the human body, there is a need to develop reliable in vitro human s...
An Organotypic Human Lymph Node Model Reveals the Importance of Fibroblastic Reticular Cells for Dendritic Cell Function
An Organotypic Human Lymph Node Model Reveals the Importance of Fibroblastic Reticular Cells for Dendritic Cell Function
Human lymph node (HuLN) models have emerged with invaluable potential for immunological research and therapeutic applicati...
Effects of Cetrorelix on Ovary and Endometrium Prior to Anti-PD-L1 Antibody in Murine Model
Effects of Cetrorelix on Ovary and Endometrium Prior to Anti-PD-L1 Antibody in Murine Model
Recent anti-cancer agents, immune checkpoint inhibitors (ICIs), have emerged as effective agents targeting the programmed ...
α-Gal Nanoparticles in CNS Trauma: I. In Vitro Activation of Microglia Towards a Pro-Healing State
α-Gal Nanoparticles in CNS Trauma: I. In Vitro Activation of Microglia Towards a Pro-Healing State
Macrophages and microglia play critical roles after spinal cord injury (SCI), with the pro-healing, anti-inflammatory (M2)...
Extraction and Characterization of Human Adipose Tissue-Derived Collagen: Toward Xeno-Free Tissue Engineering
Extraction and Characterization of Human Adipose Tissue-Derived Collagen: Toward Xeno-Free Tissue Engineering
Collagen is a key component of connective tissue and has been frequently used in the fabrication of medical devices for ti...
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