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Development of Electrospinning Setup for Vascular Tissue-Engineering Application with Thick-Hierarchical Fiber Alignment
Development of Electrospinning Setup for Vascular Tissue-Engineering Application with Thick-Hierarchical Fiber Alignment
Tissue engineering holds promise for vascular repair and regeneration by mimicking the extracellular matrix of blood vesse...
Reducing Healing Period with DDM/rhBMP-2 Grafting for Early Loading in Dental Implant Surgery
Reducing Healing Period with DDM/rhBMP-2 Grafting for Early Loading in Dental Implant Surgery
Traditionally, dental implants require a healing period of 4 to 9 months for osseointegration, with longer recove...
Exosomes and Exosome-Mimetics for Atopic Dermatitis Therapy
Exosomes and Exosome-Mimetics for Atopic Dermatitis Therapy
Exosomes and exosome mimetics are used as alternatives to cell therapy. They have shown potential in treating skin disorde...
∆9-Tetrahydrocannabinol Increases Growth Factor Release by Cultured Adipose Stem Cells and Adipose Tissue in vivo
∆9-Tetrahydrocannabinol Increases Growth Factor Release by Cultured Adipose Stem Cells and Adipose Tissue in vivo
Because of its biocompatibility and its soft and dynamic nature, the grafting of adipose tissue is regarded an ideal techn...
Enhancing Cardiomyocyte Purity through Lactate-Based Metabolic Selection
Enhancing Cardiomyocyte Purity through Lactate-Based Metabolic Selection
Direct reprogramming of fibroblasts into chemically induced cardiomyocyte-like cells (CiCMs) through small molecules prese...
Biofabricated 3D Intestinal Models as an Alternative to Animal-Based Approaches for Drug Toxicity Assays
Biofabricated 3D Intestinal Models as an Alternative to Animal-Based Approaches for Drug Toxicity Assays
The main challenge in new drug development is accurately predicting the human response in preclinical models. In this stud...
Rapid Video Analysis for Contraction Synchrony of Human Induced Pluripotent Stem Cells-Derived Cardiac Tissues
Rapid Video Analysis for Contraction Synchrony of Human Induced Pluripotent Stem Cells-Derived Cardiac Tissues
The contraction behaviors of cardiomyocytes (CMs), especially contraction synchrony, are crucial factors reflecting their ...
Regenerative Functions of Regulatory T Cells and Current Strategies Utilizing Mesenchymal Stem Cells in Immunomodulatory Tissue Regeneration
Regenerative Functions of Regulatory T Cells and Current Strategies Utilizing Mesenchymal Stem Cells in Immunomodulatory Tissue Regeneration
Regulatory T cells (Tregs) are essential for maintaining immune homeostasis and facilitating tissue regeneration by foster...
Immunomodulation Effects of Porcine Cartilage Acellularized Matrix (pCAM) for Osteoarthritis Treatment
Immunomodulation Effects of Porcine Cartilage Acellularized Matrix (pCAM) for Osteoarthritis Treatment
Pain reduction, immunomodulation, and cartilage repair are key therapeutic goals in osteoarthritis (OA) treatment. In this...
Implantation of Islets Co-Seeded with Tregs in a Novel Biomaterial Reverses Diabetes in the NOD Mouse Model
Implantation of Islets Co-Seeded with Tregs in a Novel Biomaterial Reverses Diabetes in the NOD Mouse Model
Type 1 diabetes (T1D) results in autoreactive T cells chronically destroying pancreatic islets. This often results in irre...
The Application of L-Serine-Incorporated Gelatin Sponge into the Calvarial Defect of the Ovariectomized Rats
The Application of L-Serine-Incorporated Gelatin Sponge into the Calvarial Defect of the Ovariectomized Rats
Osteoporosis, characterized by decreased bone mineral density due to an imbalance between osteoblast and osteoclast activi...
Unlocking Therapeutic Potential: Camphorquinone’s Role in Alleviating Non-Alcoholic Fatty Liver Disease via SIRT1/LKB1/AMPK Pathway Activation
Unlocking Therapeutic Potential: Camphorquinone’s Role in Alleviating Non-Alcoholic Fatty Liver Disease via SIRT1/LKB1/AMPK Pathway Activation
Non-alcoholic fatty liver disease (NAFLD) is a pathological condition that increase the risk of simple steatosis to hepato...
Efficacy of Bone Regeneration Cell Therapy Using Mesenchymal Stem Cells Originating from Embryonic Stem Cells in Animal Models; Bone Defects and Osteomyelitis
Efficacy of Bone Regeneration Cell Therapy Using Mesenchymal Stem Cells Originating from Embryonic Stem Cells in Animal Models; Bone Defects and Osteomyelitis
Bone defects are commonly encountered due to accidents, diseases, or aging, and the demand for effective bone regeneration...
Establishment of an In Vitro Embryo-Endometrium Model Using Alginate-Embedded Mouse Embryos and Human Embryoid Body
Establishment of an In Vitro Embryo-Endometrium Model Using Alginate-Embedded Mouse Embryos and Human Embryoid Body
Embryo-endometrium cross-talk is one of the critical processes for implantation, and unsuccessful cross-talk leads to infe...
Gingival Mesenchymal Stem Cells: A Periodontal Regenerative Substitute
Gingival Mesenchymal Stem Cells: A Periodontal Regenerative Substitute
Gingival mesenchymal stem cells (GMSCs) are distinctive homogenous subset of mesenchymal stem cells (MSCs), which has its ...
Development of Zinc-Containing Chitosan/Gelatin Coatings with Immunomodulatory Effect for Soft Tissue Sealing around Dental Implants
Development of Zinc-Containing Chitosan/Gelatin Coatings with Immunomodulatory Effect for Soft Tissue Sealing around Dental Implants
Soft tissue integration (STI) around dental implant abutments is a prerequisite to prevent bacterial invasion and achieve ...
Enhancing Skin Regeneration Efficacy of Human Dermal Fibroblasts Using Carboxymethyl Cellulose-Coated Biodegradable Polymer
Enhancing Skin Regeneration Efficacy of Human Dermal Fibroblasts Using Carboxymethyl Cellulose-Coated Biodegradable Polymer
Polylactic acid (PLA) is extensively used in the medical and cosmetic industries for skin regeneration and as a dermal fil...
Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying Circ-Tulp4 Attenuate Diabetes Mellitus with Nonalcoholic Fatty Liver Disease by Inhibiting Cell Pyroptosis through the HNRNPC/ABHD6 Axis
Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying Circ-Tulp4 Attenuate Diabetes Mellitus with Nonalcoholic Fatty Liver Disease by Inhibiting Cell Pyroptosis through the HNRNPC/ABHD6 Axis
Diabetes mellitus with nonalcoholic fatty liver disease (DM-NAFLD) represents a complex metabolic syndrome with significan...
Lipid Priming of Adipose Mesenchymal Stromal Cells with Docosahexaenoic Acid: Impact on Cell Differentiation, Senescence and the Secretome Neuroregulatory Profile
Lipid Priming of Adipose Mesenchymal Stromal Cells with Docosahexaenoic Acid: Impact on Cell Differentiation, Senescence and the Secretome Neuroregulatory Profile
Priming strategies that improve the functionality of MSCs may be required to address issues limiting successful clinical t...
Effects of Late-Passage Small Umbilical Cord–Derived Fast Proliferating Cells on Tenocytes from Degenerative Rotator Cuff Tears under an Interleukin 1β-Induced Tendinopathic Environment
Effects of Late-Passage Small Umbilical Cord–Derived Fast Proliferating Cells on Tenocytes from Degenerative Rotator Cuff Tears under an Interleukin 1β-Induced Tendinopathic Environment
Tendinopathy is a chronic tendon disease. Mesenchymal stem cells (MSCs), known for their anti-inflammatory properties, may...
Preparation and Evaluation of Poloxamer/Carbopol In-Situ Gel Loaded with Quercetin: In-Vitro Drug Release and Cell Viability Study
Preparation and Evaluation of Poloxamer/Carbopol In-Situ Gel Loaded with Quercetin: In-Vitro Drug Release and Cell Viability Study
Periodontitis is a severe chronic inflammatory disease, whose traditional systemic antimicrobial therapy faces great limit...
A Study on iPSC-Associated Factors in the Generation of Hepatocytes
A Study on iPSC-Associated Factors in the Generation of Hepatocytes
Hepatocytes are an attractive cell source in hepatic tissue engineering because they are the primary cells of the liver, m...
In Vitro Assessment of Injectable Bone Marrow Aspirate Concentrates Compared to Injectable Platelet-Rich Fibrin
In Vitro Assessment of Injectable Bone Marrow Aspirate Concentrates Compared to Injectable Platelet-Rich Fibrin
Injectable platelet-rich fibrin (iPRF), a liquid form of PRF that is prepared from peripheral blood without anticoagulants...
Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
Factor H and membrane inhibitor of reactive lysis (CD59) are key regulators of complement activation. Mesenchymal stem cel...
The Effect of Platelet Fibrin Plasma (PFP) on Postoperative Refractory Wounds: Physiologically Concentrated Platelet Plasma in Wound Repair
The Effect of Platelet Fibrin Plasma (PFP) on Postoperative Refractory Wounds: Physiologically Concentrated Platelet Plasma in Wound Repair
Surgical wounds that can’t complete primary healing three weeks after surgery are called postoperative refractory wo...
Exosomes-Shuttled lncRNA SNHG7 by Bone Marrow Mesenchymal Stem Cells Alleviates Osteoarthritis Through Targeting miR-485-5p/FSP1 Axis-Mediated Chondrocytes Ferroptosis and Inflammation
Exosomes-Shuttled lncRNA SNHG7 by Bone Marrow Mesenchymal Stem Cells Alleviates Osteoarthritis Through Targeting miR-485-5p/FSP1 Axis-Mediated Chondrocytes Ferroptosis and Inflammation
Osteoarthritis (OA), a degenerative joint disorder, is a major reason of disability in adults. Accumulating evidences have...
Macrophage Polarization: A Novel Target and Strategy for Pathological Scarring
Macrophage Polarization: A Novel Target and Strategy for Pathological Scarring
Abnormal scarring imposes considerable challenges and burdens on the lives of patients and healthcare system. Macrophages ...
Perfusion Bioreactor Conditioning of Small-diameter Plant-based Vascular Grafts
Perfusion Bioreactor Conditioning of Small-diameter Plant-based Vascular Grafts
Vascular grafts are mainly composed of synthetic materials, but are prone to thrombosis and intimal hyperplasia at small d...
Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model
Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model
The developmental abnormality spina bifida is hallmarked by missing tissues (e.g. skin) and exposure of the spinal cord to...
Determining Which Hydrostatic Pressure Regimes Promote Osteogenesis in Human Mesenchymal Stem Cells
Determining Which Hydrostatic Pressure Regimes Promote Osteogenesis in Human Mesenchymal Stem Cells
Compressive loading of bone causes hydrostatic pressure changes which have been proposed as an osteogenic differentiation ...
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