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LncRNA-ENST00000421645 promotes T cells to secrete IFN-γ by sponging PCM-1 in neurosyphilis
Aim: Neurosyphilis patients exhibited significant expression of long noncoding RNA (lncRNA) in peripheral blood T lymphocy...
DNA methylation detection technology and plasma-based methylation biomarkers in screening of gastrointestinal carcinoma
DNA methylation is of paramount importance for the evolution of human cancers. Its high sensitivity and specificity make i...
Novel epigenetic link between gestational diabetes mellitus and macrosomia
Background & objectives: Examine maternal gestational diabetes mellitus (GDM), macrosomia and DNA methylation in candi...
NEAT1 functions as a key mediator of BMP2 to promote osteogenic differentiation of renal interstitial fibroblasts
Aim: To clarify the mechanism of NEAT1, an aberrantly upregulated lncRNA in Randall's plaques (RP) similar to biomineraliz...
DNA methylation differences in cortical grey and white matter in schizophrenia
Aim: Identify grey- and white-matter-specific DNA-methylation differences between schizophrenia (SCZ) patients and control...
LINC01133 hampers the development of gastric cancer through increasing SST via binding to microRNA-576-5p
Aim: Our study aimed at investigating how LINC01133 functions in gastric cancer (GC) progression. Materials & methods:...
Cataloging recent advances in epigenetic alterations in major mental disorders and autism
During the last two decades, diverse epigenetic modifications including DNA methylation, histone modifications, RNA editin...
Predicting outcome in higher-risk myelodysplastic syndrome patients treated with azacitidine
5-Azacitidine (5-AZA) is widely used for the treatment of higher-risk myelodysplastic syndromes. However, response and sur...
A method of sample-wise region-set enrichment analysis for DNA methylomics
Aim: Gene set analysis has commonly been used to interpret DNA methylome data. However, summarizing the DNA methylation le...
Implication of epitranscriptomics in trained innate immunity and COVID-19
This study was supported by Indian Council of Medical Research (DHR-GIA, 2020-9530 to A. Paramasivam), Government of India...
DNA methylation in chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD), a complex disease with polygenetic tendency, is one of the most important he...
External validation of integrated genetic-epigenetic biomarkers for predicting incident coronary heart disease
Aim: The Framingham Risk Score (FRS) and ASCVD Pooled Cohort Equation (PCE) for predicting risk for incident coronary hear...
Comprehensive analysis of differentially expressed long noncoding RNAs, miRNAs and mRNAs in breast cancer brain metastasis
Aim: To delineate the transcriptomic landscape and potential molecular mechanisms of breast cancer brain metastasis (BCBM)...
Intergenerational effects of maternal post-traumatic stress disorder on offspring epigenetic patterns and cortisol levels
Aim: To investigate the association between maternal post-traumatic stress disorder (PTSD) during pregnancy and offspring ...
Genome-wide associations between alcohol consumption and blood DNA methylation: evidence from twin study
Aim: Alcohol intake alters DNA methylation profiles and methylation might mediate the association between alcohol and dise...
HDL-enriched miR-30a-5p is associated with HDL-cholesterol levels and glucose metabolism in healthy men and women
Aim: To investigate the associations between high-density lipoprotein (HDL)-enriched miRNAs and the cardiometabolic profil...
Changes of BDNF exon IV DNA methylation are associated with methamphetamine dependence
Aim: We investigated DNA methylation of BDNF in methamphetamine (METH) dependence in humans and an animal model. Materials...
Early-life stress induces genome-wide sex-dependent miRNA expression and correlation across limbic brain areas in rats
Aims: The aim of this study was to assess regional- and sex-dependent changes in miRNA expression resulting from early-lif...
High-throughput miRNA sequencing of the human placenta: expression throughout gestation
Aim: To understand miRNA changes across gestation in healthy human placentae. This is essential before miRNAs can be used ...
Expression profiles and functional analysis of plasma tRNA-derived small RNAs in children with fulminant myocarditis
Aim: Fulminant myocarditis (FM) has neither validated biomarkers nor well-established therapy. Roles of tRNA-derived small...
miR-498 inhibits autophagy and M2-like polarization of tumor-associated macrophages in esophageal cancer via MDM2/ATF3
Structured abstract Aim: To elucidate the effect of miRNA (miR)-498 on autophagy and M2-like macrophage polarization in es...
Epigenomics in the single cell era, an important read out for genome function and cell identity
The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial ...
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