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CircRNF121 knockdown suppresses the progression of cervical cancer by regulating miR‐153‐3p/ATF2 axis and wnt/β‐catenin pathway
CircRNF121 knockdown suppresses the progression of cervical cancer by regulating miR‐153‐3p/ATF2 axis and wnt/β‐catenin pathway
Abstract Cervical cancer (CC) is a common malignancy in gynecology. Emerging evidence has demonstrated that circular RNAs ...
Road‐map of pre‐clinical treatment for Visceral Leishmaniasis
Road‐map of pre‐clinical treatment for Visceral Leishmaniasis
Abstract Visceral leishmaniasis (VL) or Kala-azar, is the most lethal form of leishmaniasis, is still prevalent in many co...
Schisandrin B ameliorates non‐alcoholic liver disease through anti‐inflammation activation in diabetic mice
Schisandrin B ameliorates non‐alcoholic liver disease through anti‐inflammation activation in diabetic mice
Abstract Type 2 diabetes mellitus (T2DM) is a metabolic risk factor associated with non-alcoholic liver disease (NAFLD). S...
CircMYBL2 regulates the resistance of cervical cancer cells to paclitaxel via miR‐665‐dependent regulation of EGFR
CircMYBL2 regulates the resistance of cervical cancer cells to paclitaxel via miR‐665‐dependent regulation of EGFR
Abstract Circular RNAs are considered to be associated with cancer resistance. This study aims to investigate the function...
CircFAT1 facilitates cervical cancer malignant progression by regulating ERK1/2 and p38 MAPK pathway through miR‐409‐3p/CDK8 axis
CircFAT1 facilitates cervical cancer malignant progression by regulating ERK1/2 and p38 MAPK pathway through miR‐409‐3p/CDK8 axis
Abstract Circular RNA FAT atypical cadherin 1 (circFAT1) has been reported to play vital roles in the progression of some ...
Investigating function of long noncoding RNA of HOTAIRM1 in progression of SKOV3 ovarian cancer cells
Investigating function of long noncoding RNA of HOTAIRM1 in progression of SKOV3 ovarian cancer cells
Abstract Ovarian cancer is one of the most heterogeneous malignancies in the field of gynecologic oncology. Deregulation o...
Potential antiviral activity of isorhamnetin against SARS‐CoV‐2 spike pseudotyped virus in vitro
Potential antiviral activity of isorhamnetin against SARS‐CoV‐2 spike pseudotyped virus in vitro
Abstract Coronavirus Disease 2019 (COVID-19) cases and deaths are still rising worldwide, there is currently no effective ...
CQMUH‐011 mitigates autoimmune hepatitis via inhibiting the function of T lymphocytes
CQMUH‐011 mitigates autoimmune hepatitis via inhibiting the function of T lymphocytes
Abstract CQMUH-011 is a modified adamantane sulfonamide compound, that inhibits macrophage proliferation and possesses ant...
Identification of kinases and kinase inhibitors for the differential targeting of Wnt/β‐catenin signaling in gastric cancer subtypes
Identification of kinases and kinase inhibitors for the differential targeting of Wnt/β‐catenin signaling in gastric cancer subtypes
Abstract The oncogenic signaling pathway Wnt is often activated in many cancers including gastric cancer. Wnt signaling pa...
New isolate from Salvinia molesta with antioxidant and urease inhibitory activity
New isolate from Salvinia molesta with antioxidant and urease inhibitory activity
Abstract Urease plays a significant role in the pathogenesis of urolithiasis pyelonephritis, urinary catheter encrustation...
Changes in the proportions of an active pharmaceutical through cocrystals
Changes in the proportions of an active pharmaceutical through cocrystals
Abstract In this study, the modulation of amounts sulfathiazolium cations in different 2,6-pyridinedicarboxylates is demon...
Silver(I)‐N‐heterocyclic carbene complexes challenge cancer; evaluation of their anticancer properties and in silico studies
Silver(I)‐N‐heterocyclic carbene complexes challenge cancer; evaluation of their anticancer properties and in silico studies
Abstract Because of the continuous need for efficient therapeutic agents against various kinds of cancers and infectious d...
Challenges of peptide and protein drug delivery by oral route: Current strategies to improve the bioavailability
Challenges of peptide and protein drug delivery by oral route: Current strategies to improve the bioavailability
Abstract Advancement in biotechnology provided a notable expansion of peptide and protein therapeutics, used as antigens, ...
Beyond its anti‐migraine properties, sumatriptan is an anti‐inflammatory agent: A systematic review
Beyond its anti‐migraine properties, sumatriptan is an anti‐inflammatory agent: A systematic review
Abstract Sumatriptan is the first available medication from triptans family that was approved by the U.S. Food and Drug Ad...
Synthesis and characterization of new pyrazole–tetrazole derivatives as new vasorelaxant agents
Synthesis and characterization of new pyrazole–tetrazole derivatives as new vasorelaxant agents
Abstract The synthesis of new functionalized tetrazole–pyrazole compounds is reported. They were fully characterize...
Discovery of novel indole‐1,2,4‐triazole derivatives as tubulin polymerization inhibitors
Discovery of novel indole‐1,2,4‐triazole derivatives as tubulin polymerization inhibitors
Abstract A series of novel indole-1,2,4-triazole derivatives have been designed, synthesized, and evaluated as potential t...
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk‐3β signal pathway
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk‐3β signal pathway
Abstract Among digestive system cancers, the extremely poor prognosis of pancreatic cancer (PC) is a pressing concern. Non...
Novel strategies to oral delivery of insulin: Current progress of nanocarriers for diabetes management
Novel strategies to oral delivery of insulin: Current progress of nanocarriers for diabetes management
Abstract Diabetes mellitus is one of the most serious public health problems in the world. Repeated daily injections of su...
Terbutaline attenuates LPS‐induced injury of pulmonary microvascular endothelial cells by cAMP/Epac signaling
Terbutaline attenuates LPS‐induced injury of pulmonary microvascular endothelial cells by cAMP/Epac signaling
Abstract Acute lung injury (ALI), characterized by an acute onset of severe hypoxemia, is a common and devastating syndrom...