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Prospective observational study of oral clonazepam to prevent high-dose busulfan-induced seizures in adult patients
Prospective observational study of oral clonazepam to prevent high-dose busulfan-induced seizures in adult patients
Busulfan at high doses has been associated with a risk of seizures. Phenytoin has been used traditionally as anti-seizure ...
A comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a randomized clinical trial
A comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a randomized clinical trial
To evaluate central quadrantectomy and nipple resection with areola preservation (CQ-NR-AP) as a new reconstructive oncopl...
Susceptibility of different mice species to chemical induction of colorectal cancer by 1,2-dimethylhydrazine
Susceptibility of different mice species to chemical induction of colorectal cancer by 1,2-dimethylhydrazine
Colorectal cancer (CRC) is a major public health concern. Animal models play a crucial role in understanding the ...
Eco-biofabrication of silver nanoparticles from Azadirachta indica, Gymnema sylvestre, and Moringa oleifera for lung cancer treatment
Eco-biofabrication of silver nanoparticles from Azadirachta indica, Gymnema sylvestre, and Moringa oleifera for lung cancer treatment
Silver nanoparticles (AgNPs) derived from natural sources have garnered significant attention due to their unique properti...
Protein expression of CD44 in patients with meningioma tumors: association with clinicopathological parameters and survival
Protein expression of CD44 in patients with meningioma tumors: association with clinicopathological parameters and survival
Meningiomas are a molecularly ill-defined heterogeneous group of indolent intracranial tumors. Though, WHO grade 1 tumors ...
Clinicopathological significance of c-MET and HER2 altered expression in bladder cancer
Clinicopathological significance of c-MET and HER2 altered expression in bladder cancer
Tumor recurrence or metastasis after surgery is a significant factor influencing bladder cancer (BC) prognosis. Novel mole...
The prevalence and clinical significance of EGFR mutations in non-small cell lung cancer patients in Egypt: a screening study
The prevalence and clinical significance of EGFR mutations in non-small cell lung cancer patients in Egypt: a screening study
Lung cancer is a form of cancer that is responsible for the largest incidence of deaths attributed to cancer worldwide. No...
Galangin promotes apoptosis by upregulating the pro-apoptotic gene BAX in triple-negative breast cancer
Galangin promotes apoptosis by upregulating the pro-apoptotic gene BAX in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and formidable subtypes of breast cancer, devoid of tar...
Clinico-epidemiological and treatment factors impact on survival in Egyptian patients with head and neck sarcoma: a retrospective case-series analysis
Clinico-epidemiological and treatment factors impact on survival in Egyptian patients with head and neck sarcoma: a retrospective case-series analysis
Head and neck sarcomas are very rare accounting for about 1% of head and neck malignancies and 5% of sarcomas. Outcomes ha...
Assessment of podocyte detachment as a pivotal step in the development of focal segmental glomerulosclerosis
Assessment of podocyte detachment as a pivotal step in the development of focal segmental glomerulosclerosis
Podocytopenia refers to a decrease in the number of podocytes. When podocytes are injured, they may detach leading to podo...
Genomic strategies for drug repurposing
Genomic strategies for drug repurposing
Functional genomics, a multidisciplinary subject, investigates the functions of genes and their products in biological sys...
Bladder cancer: a retrospective audit at a single radiation oncology unit of an academic hospital in Johannesburg, South Africa
Bladder cancer: a retrospective audit at a single radiation oncology unit of an academic hospital in Johannesburg, South Africa
Bladder cancer (BCa) is one of the most common urological cancers and remains a leading cause of cancer-related mortality ...
Practical immunomodulatory landscape of glioblastoma multiforme (GBM) therapy
Practical immunomodulatory landscape of glioblastoma multiforme (GBM) therapy
Glioblastoma multiforme (GBM) is the most common harmful high-grade brain tumor with high mortality and low survival rate....
Association of IL-6 G-174C (rs1800795) variant with the susceptibility to hepatocellular carcinoma in patients with chronic hepatitis
Association of IL-6 G-174C (rs1800795) variant with the susceptibility to hepatocellular carcinoma in patients with chronic hepatitis
An ineffective immune response resulting from dysregulation of cytokine production might encourage viral persistence and c...
Utility of clinical, laboratory, and lymph node MYD88 L265P mutation in risk assessment of diffuse large B-cell lymphoma patients
Utility of clinical, laboratory, and lymph node MYD88 L265P mutation in risk assessment of diffuse large B-cell lymphoma patients
Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma and is characterized by heterogeneity in biolo...
Identification of an immune-related genes signature in lung adenocarcinoma to predict survival and response to immune checkpoint inhibitors
Identification of an immune-related genes signature in lung adenocarcinoma to predict survival and response to immune checkpoint inhibitors
Although advances in immune checkpoint inhibitor (ICI) research have provided a new treatment approach for lung adenocarci...
Serum uric acid level can predict asymptomatic brain metastasis at diagnosis in patients with small cell lung cancer
Serum uric acid level can predict asymptomatic brain metastasis at diagnosis in patients with small cell lung cancer
The aim of this study was to determine the relationship between serum uric acid level at diagnosis and asymptomatic brain ...
Dose advantage of abdominal deep inspiratory breath-hold (aDIBH) in postoperative adjuvant radiotherapy for left breast cancer
Dose advantage of abdominal deep inspiratory breath-hold (aDIBH) in postoperative adjuvant radiotherapy for left breast cancer
We explored the dosimetric efficacy of the abdominal deep inspiration breath hold (aDIBH) technique using an audio-guided ...
Interdependency and differential expression of ERK1 and ERK2 in breast and melanoma cell lines
Interdependency and differential expression of ERK1 and ERK2 in breast and melanoma cell lines
Regulatory mechanism of ERK1 and ERK2, their mechanisms of action, and how they impact on development, growth, and homeost...
Prognostic factors and outcome of relapsed/progressive pediatric Ewing sarcoma: single-center 10-year experience
Prognostic factors and outcome of relapsed/progressive pediatric Ewing sarcoma: single-center 10-year experience
Ewing sarcoma (ES) is the second most common primary malignant bone tumor in children and adolescents. Despite more intens...
ACTH-producing adrenocortical carcinoma: an exceedingly rare diagnosis
ACTH-producing adrenocortical carcinoma: an exceedingly rare diagnosis
Adrenocortical carcinoma is a very rare endocrinopathy that has a poor prognosis and is frequently associated with ACTH-in...
Correlations of pathomorphological parameters between lesions at the invasive front and lymph node metastases in colorectal cancer: a retrospective clinical study
Correlations of pathomorphological parameters between lesions at the invasive front and lymph node metastases in colorectal cancer: a retrospective clinical study
Lymph node (LN) metastasis is one of the most important indicators to evaluate stage, choose treatment strategy, and predi...
Assessment of peripheral dose as a function of distance and depth from cobalt-60 beam in water phantom using TLD-100
Assessment of peripheral dose as a function of distance and depth from cobalt-60 beam in water phantom using TLD-100
Innovations in cancer treatment have contributed to the improved survival rate of cancer patients. The cancer survival rat...
Evaluating circulating cell-free DNA and DNA integrity index as biomarkers in non-small cell lung cancer
Evaluating circulating cell-free DNA and DNA integrity index as biomarkers in non-small cell lung cancer
Analysis of free DNA molecules shed from tumour cells in plasma of patients referred as circulating tumour DNA (ctDNA) wit...
Predicting disease recurrence in breast cancer patients using machine learning models with clinical and radiomic characteristics: a retrospective study
Predicting disease recurrence in breast cancer patients using machine learning models with clinical and radiomic characteristics: a retrospective study
The goal is to use three different machine learning models to predict the recurrence of breast cancer across a very hetero...
Prognosis of transarterial chemoembolization-sorafenib compared to transarterial chemoembolization-alone in hepatocellular carcinoma stage C: a systematic review
Prognosis of transarterial chemoembolization-sorafenib compared to transarterial chemoembolization-alone in hepatocellular carcinoma stage C: a systematic review
This systematic review aims to compare the prognosis of treatment transarterial chemoembolization (TACE) combined with sor...
Breaking barriers: supporting hematopoietic stem cell transplant program through collaborative radiation therapy service from a physically distant center
Breaking barriers: supporting hematopoietic stem cell transplant program through collaborative radiation therapy service from a physically distant center
Total body irradiation (TBI) for hematopoietic stem cell transplant (HSCT) has certain distinct advantages, such as unifor...
Role of pre-operative endovascular embolization of a giant sacrococcygeal teratoma in neonate: a case report
Role of pre-operative endovascular embolization of a giant sacrococcygeal teratoma in neonate: a case report
Giant sacrococcygeal teratomas (SCTs) are at risk of perinatal morbidity and mortality due to their high vascularity. Pre-...
Evaluating the efficacy and safety of nivolumab and ipilimumab combination therapy compared to nivolumab monotherapy in advanced cancers (excluding melanoma): a systemic review and meta-analysis
Evaluating the efficacy and safety of nivolumab and ipilimumab combination therapy compared to nivolumab monotherapy in advanced cancers (excluding melanoma): a systemic review and meta-analysis
Nivolumab (Nivo) and ipilimumab (Ipi) have revolutionized cancer treatment by targeting different pathways. Their combinat...
miR-939, as an important regulator in various cancers pathogenesis, has diagnostic, prognostic, and therapeutic values: a review
miR-939, as an important regulator in various cancers pathogenesis, has diagnostic, prognostic, and therapeutic values: a review
MicroRNAs (miRNAs or miRs) are highly conserved non-coding RNAs with a short length (18–24 nucleotides) that directl...
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