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Genomic strategies for drug repurposing
Genomic strategies for drug repurposing
Functional genomics, a multidisciplinary subject, investigates the functions of genes and their products in biological sys...
Bladder cancer: a retrospective audit at a single radiation oncology unit of an academic hospital in Johannesburg, South Africa
Bladder cancer: a retrospective audit at a single radiation oncology unit of an academic hospital in Johannesburg, South Africa
Bladder cancer (BCa) is one of the most common urological cancers and remains a leading cause of cancer-related mortality ...
Practical immunomodulatory landscape of glioblastoma multiforme (GBM) therapy
Practical immunomodulatory landscape of glioblastoma multiforme (GBM) therapy
Glioblastoma multiforme (GBM) is the most common harmful high-grade brain tumor with high mortality and low survival rate....
Association of IL-6 G-174C (rs1800795) variant with the susceptibility to hepatocellular carcinoma in patients with chronic hepatitis
Association of IL-6 G-174C (rs1800795) variant with the susceptibility to hepatocellular carcinoma in patients with chronic hepatitis
An ineffective immune response resulting from dysregulation of cytokine production might encourage viral persistence and c...
Utility of clinical, laboratory, and lymph node MYD88 L265P mutation in risk assessment of diffuse large B-cell lymphoma patients
Utility of clinical, laboratory, and lymph node MYD88 L265P mutation in risk assessment of diffuse large B-cell lymphoma patients
Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma and is characterized by heterogeneity in biolo...
Identification of an immune-related genes signature in lung adenocarcinoma to predict survival and response to immune checkpoint inhibitors
Identification of an immune-related genes signature in lung adenocarcinoma to predict survival and response to immune checkpoint inhibitors
Although advances in immune checkpoint inhibitor (ICI) research have provided a new treatment approach for lung adenocarci...
Serum uric acid level can predict asymptomatic brain metastasis at diagnosis in patients with small cell lung cancer
Serum uric acid level can predict asymptomatic brain metastasis at diagnosis in patients with small cell lung cancer
The aim of this study was to determine the relationship between serum uric acid level at diagnosis and asymptomatic brain ...
Dose advantage of abdominal deep inspiratory breath-hold (aDIBH) in postoperative adjuvant radiotherapy for left breast cancer
Dose advantage of abdominal deep inspiratory breath-hold (aDIBH) in postoperative adjuvant radiotherapy for left breast cancer
We explored the dosimetric efficacy of the abdominal deep inspiration breath hold (aDIBH) technique using an audio-guided ...
Interdependency and differential expression of ERK1 and ERK2 in breast and melanoma cell lines
Interdependency and differential expression of ERK1 and ERK2 in breast and melanoma cell lines
Regulatory mechanism of ERK1 and ERK2, their mechanisms of action, and how they impact on development, growth, and homeost...
Prognostic factors and outcome of relapsed/progressive pediatric Ewing sarcoma: single-center 10-year experience
Prognostic factors and outcome of relapsed/progressive pediatric Ewing sarcoma: single-center 10-year experience
Ewing sarcoma (ES) is the second most common primary malignant bone tumor in children and adolescents. Despite more intens...
ACTH-producing adrenocortical carcinoma: an exceedingly rare diagnosis
ACTH-producing adrenocortical carcinoma: an exceedingly rare diagnosis
Adrenocortical carcinoma is a very rare endocrinopathy that has a poor prognosis and is frequently associated with ACTH-in...
Correlations of pathomorphological parameters between lesions at the invasive front and lymph node metastases in colorectal cancer: a retrospective clinical study
Correlations of pathomorphological parameters between lesions at the invasive front and lymph node metastases in colorectal cancer: a retrospective clinical study
Lymph node (LN) metastasis is one of the most important indicators to evaluate stage, choose treatment strategy, and predi...
Assessment of peripheral dose as a function of distance and depth from cobalt-60 beam in water phantom using TLD-100
Assessment of peripheral dose as a function of distance and depth from cobalt-60 beam in water phantom using TLD-100
Innovations in cancer treatment have contributed to the improved survival rate of cancer patients. The cancer survival rat...
Evaluating circulating cell-free DNA and DNA integrity index as biomarkers in non-small cell lung cancer
Evaluating circulating cell-free DNA and DNA integrity index as biomarkers in non-small cell lung cancer
Analysis of free DNA molecules shed from tumour cells in plasma of patients referred as circulating tumour DNA (ctDNA) wit...
Predicting disease recurrence in breast cancer patients using machine learning models with clinical and radiomic characteristics: a retrospective study
Predicting disease recurrence in breast cancer patients using machine learning models with clinical and radiomic characteristics: a retrospective study
The goal is to use three different machine learning models to predict the recurrence of breast cancer across a very hetero...
Prognosis of transarterial chemoembolization-sorafenib compared to transarterial chemoembolization-alone in hepatocellular carcinoma stage C: a systematic review
Prognosis of transarterial chemoembolization-sorafenib compared to transarterial chemoembolization-alone in hepatocellular carcinoma stage C: a systematic review
This systematic review aims to compare the prognosis of treatment transarterial chemoembolization (TACE) combined with sor...
Breaking barriers: supporting hematopoietic stem cell transplant program through collaborative radiation therapy service from a physically distant center
Breaking barriers: supporting hematopoietic stem cell transplant program through collaborative radiation therapy service from a physically distant center
Total body irradiation (TBI) for hematopoietic stem cell transplant (HSCT) has certain distinct advantages, such as unifor...
Role of pre-operative endovascular embolization of a giant sacrococcygeal teratoma in neonate: a case report
Role of pre-operative endovascular embolization of a giant sacrococcygeal teratoma in neonate: a case report
Giant sacrococcygeal teratomas (SCTs) are at risk of perinatal morbidity and mortality due to their high vascularity. Pre-...
Evaluating the efficacy and safety of nivolumab and ipilimumab combination therapy compared to nivolumab monotherapy in advanced cancers (excluding melanoma): a systemic review and meta-analysis
Evaluating the efficacy and safety of nivolumab and ipilimumab combination therapy compared to nivolumab monotherapy in advanced cancers (excluding melanoma): a systemic review and meta-analysis
Nivolumab (Nivo) and ipilimumab (Ipi) have revolutionized cancer treatment by targeting different pathways. Their combinat...
miR-939, as an important regulator in various cancers pathogenesis, has diagnostic, prognostic, and therapeutic values: a review
miR-939, as an important regulator in various cancers pathogenesis, has diagnostic, prognostic, and therapeutic values: a review
MicroRNAs (miRNAs or miRs) are highly conserved non-coding RNAs with a short length (18–24 nucleotides) that directl...
Radio-anatomical evaluation of clinical and radiomic profile of multi-parametric magnetic resonance imaging of de novo glioblastoma multiforme
Radio-anatomical evaluation of clinical and radiomic profile of multi-parametric magnetic resonance imaging of de novo glioblastoma multiforme
Glioblastoma (GBM) is a fatal, fast-growing, and aggressive brain tumor arising from glial cells or their progenitors. It ...
Investigating the level of vitamin D receptor gene expression in two tumoral and healthy breast tissues in breast cancer patients and its association with prognostic factors
Investigating the level of vitamin D receptor gene expression in two tumoral and healthy breast tissues in breast cancer patients and its association with prognostic factors
Breast cancer is one of the most common cancers known among women. This study aimed to investigate the level of vitamin D ...
A comparative study in left-sided breast cancer treated with moderate deep inspiratory breath hold versus free breathing
A comparative study in left-sided breast cancer treated with moderate deep inspiratory breath hold versus free breathing
The moderate deep inspiratory breath hold (mDIBH) is a modality famed for cardiac sparing. Prospective studies based on th...
Immunochemistry-based quantification of tumor-infiltrating lymphocytes and immunoscore as prognostic biomarkers in bladder cancer
Immunochemistry-based quantification of tumor-infiltrating lymphocytes and immunoscore as prognostic biomarkers in bladder cancer
Tumor-infiltrating lymphocytes (TILs) and the derived immunoscore (IS) have gained considerable attention over the last de...
CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
CircRNAs and miRNAs are involved in the progression of tumor. CircMCTP2 is considered as a novel tumor promoter. However, ...
Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma
Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma
The progression of metastasis, a complex systemic disease, is facilitated by interactions between tumor cells and their is...
Developing an efficient method for melanoma detection using CNN techniques
Developing an efficient method for melanoma detection using CNN techniques
More and more genetic and metabolic abnormalities are now known to cause cancer, which is typically deadly. Any bodily par...
Significance of OCT3/4 and SOX2 antigens expression by leukemic blast cells in adult acute leukemia
Significance of OCT3/4 and SOX2 antigens expression by leukemic blast cells in adult acute leukemia
This study aimed to address the prognostic impact of SOX2 and OCT3/4 expression on adult acute leukemia patients’ ou...
Platelet-to-albumin ratio and radiation-induced lymphopenia—prognostic biomarker for carcinoma esophagus
Platelet-to-albumin ratio and radiation-induced lymphopenia—prognostic biomarker for carcinoma esophagus
Esophageal cancer has a poor survival outcome with 5-year OS at 16.7% despite treatment. Some inflammation-based prognosti...
PD-L1 expression and its significance in advanced NSCLC: real-world experience from a tertiary care center
PD-L1 expression and its significance in advanced NSCLC: real-world experience from a tertiary care center
Targeted therapies against programmed death ligand-1 (PD-L1) in non-small cell lung cancer (NSCLC) have revolutionized the...
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