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CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
CircRNAs and miRNAs are involved in the progression of tumor. CircMCTP2 is considered as a novel tumor promoter. However, ...
Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma
Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma
The progression of metastasis, a complex systemic disease, is facilitated by interactions between tumor cells and their is...
Developing an efficient method for melanoma detection using CNN techniques
Developing an efficient method for melanoma detection using CNN techniques
More and more genetic and metabolic abnormalities are now known to cause cancer, which is typically deadly. Any bodily par...
Significance of OCT3/4 and SOX2 antigens expression by leukemic blast cells in adult acute leukemia
Significance of OCT3/4 and SOX2 antigens expression by leukemic blast cells in adult acute leukemia
This study aimed to address the prognostic impact of SOX2 and OCT3/4 expression on adult acute leukemia patients’ ou...
Platelet-to-albumin ratio and radiation-induced lymphopenia—prognostic biomarker for carcinoma esophagus
Platelet-to-albumin ratio and radiation-induced lymphopenia—prognostic biomarker for carcinoma esophagus
Esophageal cancer has a poor survival outcome with 5-year OS at 16.7% despite treatment. Some inflammation-based prognosti...
PD-L1 expression and its significance in advanced NSCLC: real-world experience from a tertiary care center
PD-L1 expression and its significance in advanced NSCLC: real-world experience from a tertiary care center
Targeted therapies against programmed death ligand-1 (PD-L1) in non-small cell lung cancer (NSCLC) have revolutionized the...
Peripheral Neutrophil to Lymphocyte Ratio (NLR), a cogent clinical adjunct for Ki-67 in breast cancer
Peripheral Neutrophil to Lymphocyte Ratio (NLR), a cogent clinical adjunct for Ki-67 in breast cancer
Clinical utility of Ki-67 immunohistochemistry (IHC) in breast cancer (BC) is mainly limited to decide for the use of chem...
Metabolic syndrome and breast cancer risk
Metabolic syndrome and breast cancer risk
Limited data are available on metabolic syndrome and its relation to breast cancer risk in Egypt. We aimed to study metabo...
REC8 regulates neuroblastoma cell proliferation, migration, invasion, and angiogenesis via STAT3/VEGF signaling
REC8 regulates neuroblastoma cell proliferation, migration, invasion, and angiogenesis via STAT3/VEGF signaling
Neuroblastoma, one of the most prevalent childhood cancers, is often treated with surgery, radiation, and chemotherapy. Ho...
Review of current literature on gestational trophoblastic neoplasia
Review of current literature on gestational trophoblastic neoplasia
Gestational Trophoblastic Neoplasia (GTN) is a disease of the reproductive age group with an incidence rate of <1% ...
Ameloblastic fibro-dentinoma: a rare mixed odontogenic tumor case report with review of literature
Ameloblastic fibro-dentinoma: a rare mixed odontogenic tumor case report with review of literature
Ameloblastic fibro-dentinoma is considered a rare, benign, mixed odontogenic tumor that occurs mainly in the posterior man...
Stem cell therapy for hepatocellular carcinoma and end-stage liver disease
Stem cell therapy for hepatocellular carcinoma and end-stage liver disease
Hepatocellular carcinoma (HCC) is a major health problem worldwide, especially for patients who are suffering from end-sta...
Micronuclei detection in oral cytologic smear: does it add diagnostic value?
Micronuclei detection in oral cytologic smear: does it add diagnostic value?
Screening and early diagnosis of oral squamous cell carcinoma (OSCC) are directly associated with increased survival rate ...
Mandibular small cell osteosarcoma: a case report and review of literature
Mandibular small cell osteosarcoma: a case report and review of literature
Small cell osteosarcoma is an extremely rare histopathological variant of conventional osteosarcoma. Due to nonspecific sy...
Outcome and prognostic factors of pediatric patients with Hodgkin lymphoma: a single-center experience
Outcome and prognostic factors of pediatric patients with Hodgkin lymphoma: a single-center experience
Hodgkin lymphoma (HL) is a highly curable malignant tumor. Risk-adapted treatment for children with HL aims to maximize su...
The relationship between coping self-efficacy and B cells in breast cancer patients
The relationship between coping self-efficacy and B cells in breast cancer patients
Breast cancer is the most common tumor among women throughout the world. Diagnosis and treatment of breast cancer are asso...
Mechanisms of HIF-driven immunosuppression in tumour microenvironment
Mechanisms of HIF-driven immunosuppression in tumour microenvironment
Hypoxia arises due to insufficient oxygen delivery to rapidly proliferating tumour cells that outpace the available blood ...
Prognostic value of S100A4 and Glypican-3 in hepatocellular carcinoma in cirrhotic HCV patients
Prognostic value of S100A4 and Glypican-3 in hepatocellular carcinoma in cirrhotic HCV patients
Both S100A4 and Glypican-3 have been known to be engaged in HCC development and progression. This study aimed to evaluate ...
Bioinformatic analysis of KIT juxtamembrane domain mutations in Syrian GIST patients: jigsaw puzzle completed
Bioinformatic analysis of KIT juxtamembrane domain mutations in Syrian GIST patients: jigsaw puzzle completed
The huge number of detected somatic KIT mutations highlights the necessity of in silico analyses that are almost absent in...
Immunohistochemical expression of P53 protein in nephroblastoma: a predictor of unfavorable prognosis
Immunohistochemical expression of P53 protein in nephroblastoma: a predictor of unfavorable prognosis
Immunohistochemical expression of P53 protein is so closely related to status of mutation of P53 gene which is tightly lin...