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Lafutidine Ameliorates Indomethacin-Induced Small Intestinal Damage in Rats by Modifying the Intestinal Mucosal Barrier, Inflammation, and Microbiota
Lafutidine Ameliorates Indomethacin-Induced Small Intestinal Damage in Rats by Modifying the Intestinal Mucosal Barrier, Inflammation, and Microbiota
<b><i>Introduction:</i></b> Nonsteroidal anti-inflammatory drug (NSAID)-induced small intestinal d...
Oncostatin M and Nivolumab Affect the Cytotoxic T-Cell Proportions and the Susceptibility to TRAIL-Induced Death in Non-Leukocyte Cell Subpopulations in Soft Tissue Sarcomas
Oncostatin M and Nivolumab Affect the Cytotoxic T-Cell Proportions and the Susceptibility to TRAIL-Induced Death in Non-Leukocyte Cell Subpopulations in Soft Tissue Sarcomas
<b><i>Introduction:</i></b> Soft tissue sarcomas (STSs) are malignant tumors arising from mesenchy...
Research Progress on the Anticancer Molecular Mechanism of Targets Regulating Cell Autophagy
Research Progress on the Anticancer Molecular Mechanism of Targets Regulating Cell Autophagy
<b><i>Background:</i></b> Autophagy is a lysosome-mediated catabolic process that maintains cell h...
Dantrolene Significantly Improves Cerebral Blood Flow in a Rat Model of Hemorrhagic Vasospasms
Dantrolene Significantly Improves Cerebral Blood Flow in a Rat Model of Hemorrhagic Vasospasms
<b><i>Introduction:</i></b> A cerebral vasospasm (CVSP) is a potent vasoconstriction of the cerebr...
Cardiometabolic Risk Factors in Atorvastatin-Treated Women with Euthyroid Autoimmune Thyroiditis
Cardiometabolic Risk Factors in Atorvastatin-Treated Women with Euthyroid Autoimmune Thyroiditis
<b><i>Introduction:</i></b> Autoimmune thyroiditis seems to be associated with increased cardiomet...
Rosuvastatin Potentiates Gonadotropin-Lowering Effects of Metformin in Postmenopausal Women: A Pilot Study
Rosuvastatin Potentiates Gonadotropin-Lowering Effects of Metformin in Postmenopausal Women: A Pilot Study
<b><i>Introduction:</i></b> Metformin reduces elevated levels of FSH and LH. In some studies, gona...
Alkaloids in Withania somnifera (L.) Dunal Root Extract Contribute to Its Anti-Inflammatory Activity
Alkaloids in Withania somnifera (L.) Dunal Root Extract Contribute to Its Anti-Inflammatory Activity
The anti-inflammatory properties of the medicinal plant <i>Withania somnifera (L.) Dunal</i> (WS) are generall...
Myo-Inositol Potentiates the Inhibitory Effect of Metformin on Prolactin Levels
Myo-Inositol Potentiates the Inhibitory Effect of Metformin on Prolactin Levels
<b><i>Introduction:</i></b> Metformin was found to reduce elevated levels of anterior pituitary ho...
Experimental Investigations of Monomethyl and Dimethyl Fumarate in an Astrocyte-Microglia Co-Culture Model of Inflammation
Experimental Investigations of Monomethyl and Dimethyl Fumarate in an Astrocyte-Microglia Co-Culture Model of Inflammation
<b><i>Introduction:</i></b> Multiple sclerosis (MS) is the most common chronic inflammatory, demye...
Melatonin Supports the Survival of Cholinergic Neurons in Organotypic Brain Slices of the Basal Nucleus of Meynert
Melatonin Supports the Survival of Cholinergic Neurons in Organotypic Brain Slices of the Basal Nucleus of Meynert
The nucleus basalis of Meynert (nBM) is the major source of cholinergic neurons in the basal forebrain, which require nerv...
DPP4 Inhibitor Sitagliptin Reduces Inflammatory Responses and Mast Cell Activation in Allergic Rhinitis
DPP4 Inhibitor Sitagliptin Reduces Inflammatory Responses and Mast Cell Activation in Allergic Rhinitis
<b><i>Introduction:</i></b> DPP4 is thought to be involved in certain immune processes and plays a...
Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis
Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis
<b><i>Introduction:</i></b> Neutrophils are a pivotal cell type in the K/BxN mouse model of rheuma...
The Aryl Hydrocarbon Receptor Ligand 6-Formylindolo(3,2-b)carbazole Promotes Estrogen Receptor Alpha and c-Fos Protein Degradation and Inhibits MCF-7 Cell Proliferation and Migration
The Aryl Hydrocarbon Receptor Ligand 6-Formylindolo(3,2-b)carbazole Promotes Estrogen Receptor Alpha and c-Fos Protein Degradation and Inhibits MCF-7 Cell Proliferation and Migration
<b><i>Introduction:</i></b> Worldwide, breast cancer is the most common cancer in women and is the...
Metformin’s Role in Hyperlactatemia and Lactic Acidosis in ICU Patients: A Systematic Review
Metformin’s Role in Hyperlactatemia and Lactic Acidosis in ICU Patients: A Systematic Review
<b><i>Introduction:</i></b> Metformin-treated patients may experience severe hyperlactatemia or la...
Comparative Efficacy and Safety of Thrombolytic Agents for Pulmonary Embolism: A Bayesian Network Meta-Analysis
Comparative Efficacy and Safety of Thrombolytic Agents for Pulmonary Embolism: A Bayesian Network Meta-Analysis
<b><i>Background:</i></b> Thrombolytic agents and anticoagulants are the two classes of medication...
Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway
Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway
<b><i>Introduction:</i></b> Hepatocellular carcinoma (HCC) is the most deadly cancer. Many signal ...
Inhibition of Kv7/M Channel Currents by Fangchinoline
Inhibition of Kv7/M Channel Currents by Fangchinoline
<b><i>Introduction:</i></b> Voltage-gated Kv7/M potassium channels play an essential role in the c...
Oral Administration of Artemisia argyi Polysaccharide Increases Estrogen Level and Maintains Blood Lipid Homeostasis in Ovariectomized Rats
Oral Administration of Artemisia argyi Polysaccharide Increases Estrogen Level and Maintains Blood Lipid Homeostasis in Ovariectomized Rats
<b><i>Introduction:</i></b> <i>Artemisia argyi</i> polysaccharide (AAP) has a benefici...
Optimal Antithrombotic Regimen in Left Atrial Appendage Occlusion: The Gordian Knot?
Optimal Antithrombotic Regimen in Left Atrial Appendage Occlusion: The Gordian Knot?
Percutaneous left atrial appendage occlusion (LAAO) is an option to reduce the risk of stroke in patients with atrial fibr...
Radioprotective Effect of Zinc Nanoparticles on Ionizing Radiation-induced Nephrotoxicity in Mice
Radioprotective Effect of Zinc Nanoparticles on Ionizing Radiation-induced Nephrotoxicity in Mice
<b><i>Introduction:</i></b> Ionizing radiation (IR) causes oxidative stress in kidneys and subsequ...
Osimertinib in the Treatment of EGFR Mutation-Positive Advanced Non-Small Cell Lung Cancer: A Meta-Analysis
Osimertinib in the Treatment of EGFR Mutation-Positive Advanced Non-Small Cell Lung Cancer: A Meta-Analysis
<b><i>Background:</i></b> Non-small cell lung cancer (NSCLC) accounts for about 85% of generally r...
High On-Treatment Platelet Reactivity: Aspirin versus Clopidogrel
High On-Treatment Platelet Reactivity: Aspirin versus Clopidogrel
<b><i>Background:</i></b> Antithrombotic regimen in patients on oral anticoagulation (OAC) post-pe...
Contents Vol. 107, 2022
Contents Vol. 107, 2022
Pharmacology...
Novel Treatment Options in Metastatic Esophageal Carcinoma: Checkpoint Inhibitors in Combination Therapies
Novel Treatment Options in Metastatic Esophageal Carcinoma: Checkpoint Inhibitors in Combination Therapies
<b><i>Background:</i></b> Metastatic esophageal carcinoma (EC) has a poor prognosis and only limit...
Protective Effects and Mechanisms of Flavonoids in Renal Ischemia-Reperfusion Injury
Protective Effects and Mechanisms of Flavonoids in Renal Ischemia-Reperfusion Injury
<b><i>Background:</i></b> Acute kidney injury (AKI) is a common and potentially fatal complication...
Factors Associated with Potentially Inappropriate Prescribing in Patients on Peritoneal Dialysis
Factors Associated with Potentially Inappropriate Prescribing in Patients on Peritoneal Dialysis
<b><i>Introduction:</i></b> Inappropriate prescribing is common in patients with end-stage kidney ...
Astragaloside IV Alleviates Atorvastatin-Induced Hepatotoxicity via AMPK/SIRT1 Pathway
Astragaloside IV Alleviates Atorvastatin-Induced Hepatotoxicity via AMPK/SIRT1 Pathway
<b><i>Introduction:</i></b> Atorvastatin (ATO) is often used to reduce blood lipids and prevent at...
Radioprotective Effect of Zinc Nanoparticles on Ionizing Radiation-Induced Nephrotoxicity in Miceds
Radioprotective Effect of Zinc Nanoparticles on Ionizing Radiation-Induced Nephrotoxicity in Miceds
<b><i>Introduction:</i></b> Ionizing radiation (IR) causes oxidative stress in kidneys and subsequ...
Luteolin Attenuates Diabetic Myocardial Hypertrophy by Inhibiting Proteasome Activity
Luteolin Attenuates Diabetic Myocardial Hypertrophy by Inhibiting Proteasome Activity
<b><i>Introduction:</i></b> Luteolin is a flavonoid polyphenolic compound exerting broad pharmacol...
LncRNA DDX11-AS1 Promotes Chemoresistance through LIN28A-Mediated ATG12 mRNA Stabilization in Breast Cancer
LncRNA DDX11-AS1 Promotes Chemoresistance through LIN28A-Mediated ATG12 mRNA Stabilization in Breast Cancer
<b><i>Introduction:</i></b> During breast cancer chemotherapy, the chemoresistance that frequently...
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