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Astragaloside IV Alleviates Atorvastatin-Induced Hepatotoxicity via AMPK/SIRT1 Pathway
Astragaloside IV Alleviates Atorvastatin-Induced Hepatotoxicity via AMPK/SIRT1 Pathway
<b><i>Introduction:</i></b> Atorvastatin (ATO) is often used to reduce blood lipids and prevent at...
Radioprotective Effect of Zinc Nanoparticles on Ionizing Radiation-Induced Nephrotoxicity in Miceds
Radioprotective Effect of Zinc Nanoparticles on Ionizing Radiation-Induced Nephrotoxicity in Miceds
<b><i>Introduction:</i></b> Ionizing radiation (IR) causes oxidative stress in kidneys and subsequ...
Luteolin Attenuates Diabetic Myocardial Hypertrophy by Inhibiting Proteasome Activity
Luteolin Attenuates Diabetic Myocardial Hypertrophy by Inhibiting Proteasome Activity
<b><i>Introduction:</i></b> Luteolin is a flavonoid polyphenolic compound exerting broad pharmacol...
LncRNA DDX11-AS1 Promotes Chemoresistance through LIN28A-Mediated ATG12 mRNA Stabilization in Breast Cancer
LncRNA DDX11-AS1 Promotes Chemoresistance through LIN28A-Mediated ATG12 mRNA Stabilization in Breast Cancer
<b><i>Introduction:</i></b> During breast cancer chemotherapy, the chemoresistance that frequently...
The Choice between Intravenous and Subcutaneous Immunoglobulins: Aspects for Consideration
The Choice between Intravenous and Subcutaneous Immunoglobulins: Aspects for Consideration
<b><i>Background:</i></b> Intravenous immunoglobulin and subcutaneous immunoglobulin preparations ...
Effects of Bile Duct Ligation and Ghrelin Treatment on the Colonic Barrier and Microbiome of Mice
Effects of Bile Duct Ligation and Ghrelin Treatment on the Colonic Barrier and Microbiome of Mice
<b><i>Introduction:</i></b> Cholestatic liver disease (CLD) is associated with intestinal barrier ...
No Evident Prognostic Benefit of Statin Use in Diffuse Large B-Cell Lymphoma Patients with Unfavorable Disease Features Treated with R-DA-EPOCH
No Evident Prognostic Benefit of Statin Use in Diffuse Large B-Cell Lymphoma Patients with Unfavorable Disease Features Treated with R-DA-EPOCH
Recent reports indicate that patients with aggressive non-Hodgkin lymphomas might benefit if concomitantly receiving stati...
Electrophysiological Safety Profile of Antiestrogenic Therapies in the Isolated Rabbit Heart
Electrophysiological Safety Profile of Antiestrogenic Therapies in the Isolated Rabbit Heart
<b><i>Introduction:</i></b> Hormone-mediated therapies are on the rise and are key therapies in th...
Effects of Rapamycin on the Expression of Redox Enzymes in Aortic Vascular Smooth Muscle Cells from Marfan Syndrome Mice
Effects of Rapamycin on the Expression of Redox Enzymes in Aortic Vascular Smooth Muscle Cells from Marfan Syndrome Mice
Activation of the mechanistic target of rapamycin (mTOR) pathway has been implicated in an increasing number of diseases, ...
The Safety and Efficacy of Clonidine in Hemodialysis Patients: A Systematic Review and Meta-Analysis
The Safety and Efficacy of Clonidine in Hemodialysis Patients: A Systematic Review and Meta-Analysis
<b><i>Background:</i></b> Clonidine is a frequently prescribed long-term antihypertensive medicati...
PKCβ Inhibition Promotes TXNIP Degradation to Ameliorate Pancreatic β-Cell Dysfunction
PKCβ Inhibition Promotes TXNIP Degradation to Ameliorate Pancreatic β-Cell Dysfunction
<b><i>Introduction:</i></b> Pancreatic β-cell dysfunction is largely regulated by TXNIP accumulati...
Tigecycline-Associated Coagulopathy: A Single-Center Retrospective Analysis
Tigecycline-Associated Coagulopathy: A Single-Center Retrospective Analysis
<b><i>Introduction:</i></b> The purpose of this study was to assess clinical characteristics and r...
Cytotoxic Effects of the Schweinfurthin Analog 5′-Methylschweinfurthin G in Malignant Plasma Cells
Cytotoxic Effects of the Schweinfurthin Analog 5′-Methylschweinfurthin G in Malignant Plasma Cells
<b><i>Introduction:</i></b> Multiple myeloma (MM) is a B plasma cell malignancy currently incurabl...
Quercetin and Osteoarthritis: A Mechanistic Review on the Present Documents
Quercetin and Osteoarthritis: A Mechanistic Review on the Present Documents
<b><i>Background:</i></b> Osteoarthritis (OA), as one of the chronic debilitating conditions, affe...
NMT1 Enhances the Stemness of NSCLC Cells by Activating the PI3K/AKT Pathway
NMT1 Enhances the Stemness of NSCLC Cells by Activating the PI3K/AKT Pathway
<b><i>Introduction:</i></b> Abundant studies have disclosed that proteins can function as pivotal ...
Treatment with Living Drugs: Pharmaceutical Aspects of CAR T Cells
Treatment with Living Drugs: Pharmaceutical Aspects of CAR T Cells
<b><i>Background:</i></b> Adoptive therapy with genetically modified T cells achieves spectacular ...
Beta-Sitosterol Modulates the Migration of Vascular Smooth Muscle Cells via the PPARG/AMPK/mTOR Pathway
Beta-Sitosterol Modulates the Migration of Vascular Smooth Muscle Cells via the PPARG/AMPK/mTOR Pathway
<b><i>Introduction:</i></b> The increased migration of vascular smooth muscle cells (VSMCs) is an ...
Diet-Induced Obesity Disrupts Histamine-Dependent Oleoylethanolamide Signaling in the Mouse Liver
Diet-Induced Obesity Disrupts Histamine-Dependent Oleoylethanolamide Signaling in the Mouse Liver
<b><i>Introduction:</i></b> Previous work suggests the existence of a paracrine signaling mechanis...
EIF5A2 Is Involved in the Biological Process of Cervical Cancer Cells through AGR2
EIF5A2 Is Involved in the Biological Process of Cervical Cancer Cells through AGR2
<b><i>Introduction:</i></b> Cervical cancer is a severe malignant tumor that endangers the health ...
Antidepressants Are Poor Inhibitors of Heat-Evoked Ion Currents Mediated by TRPM2
Antidepressants Are Poor Inhibitors of Heat-Evoked Ion Currents Mediated by TRPM2
<b><i>Introduction:</i></b> The heat and redox-sensitive ion channel TRPM2 was reported to be a ca...
Fenretinide Reduces Intestinal Mucin-2-Positive Goblet Cells in Chronic Alcohol Abuse
Fenretinide Reduces Intestinal Mucin-2-Positive Goblet Cells in Chronic Alcohol Abuse
<b><i>Introduction:</i></b> Alcohol-induced thickening of the gut mucosal layer and increased expr...