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Challenges in the management of primary central nervous system lymphoma
Primary central nervous system lymphoma (PCNSL) is an invasive extranodal non-Hodgkin lymphoma (NHL) confined to the centr...
A Systematic Review of Health-related Quality of Life Outcomes in Psychosocial Intervention Trials for Adolescent and Young Adult Cancer Survivors
Using the CRediT author statement format, individual author contributions to the manuscriptwere as follows:Karly M. Murphy...
Application of VEGF/VEGFR peptide vaccines in cancer: A systematic review of clinical trials
Angiogenic factors are crucial in the development of human cancers, and the most prominent is VEGF/VEGF receptors (VEGFRs)...
The 2022 Assisi Think Tank Meeting: White paper on optimising radiation therapy for breast cancer
Liesbeth Boersma, MD is radiation oncologist at Dept. Radiation Oncology making and innovation implementation. She is memb...
Therapeutic strategies targeting metabolic characteristics of cancer cells
Jiuwei Cui, chief physician, professor, doctoral tutor. She engaged in research on accurate diagnosis and treatment of tum...
Correlation of Bcl-2 expression with prognosis and survival in patients with head and neck cancer: A systematic review and meta-analysis
Fábio França Vieira e Silva, DDS, Pathology Expert, M.Sc. in Molecular Oncology, Ph.D. Dentist expert in Pathology and Mol...
Revisiting the role of alkylating agents in multiple myeloma: Up-to-date evidence and future perspectives
Multiple myeloma (MM) is a hematologic neoplasm characterized by a bone marrow (BM)-predominant proliferation of malignant...
Erythrocytes: Member of the immune system that should not be ignored
Erythrocytes (red blood cells, RBCs) are the most abundant blood cell in the blood and are the primary vehicle carrying ox...
From preclinical efficacy to 2022 (36.7 months median follow -up) updated CROWN trial, lorlatinib is the preferred 1st-line treatment of advanced ALK+ NSCLC
Sai-Hong Ignatius Ou is the Hamoui Salous Endowed chair in Thoracic Oncology Research and Health Science Clinical Professo...
The PANcreatic Disease ReseArch (PANDoRA) consortium: Ten years’ experience of association studies to understand the genetic architecture of pancreatic cancer
This multi-institutional review explored associations between radiation dose-volume histogram (DVH) parameters and cardiop...
Novel therapeutic strategies for recurrent SCLC
SCLC is an aggressive disease that accounts for approximately 15% of all lung cancer cases. Despite significant advancemen...
The prognostic role of p53 mutations in metastatic colorectal cancer: a systematic review and meta-analysis
Alessandro Ottaiano is an Oncologist working at the SSD-Innovative Therapies for Abdominal Metastases at the Department of...
A systematic review and meta-analysis on the Optimal Treatment duration of cHEckpoint inhibitoRS in solid tumors: the OTHERS study
In recent years, immunotherapy has gained growing importance in oncology and, immune checkpoint inhibitors (ICIs), specifi...
Efficacy of Stereotactic Radiosurgery as Single or Combined Therapy for Brain Metastasis: A Systematic Review and Meta-Analysis
Antonio Meola M.D. Ph.D graduated Summa cum Laude and Research Honors at the University of Pisa, Italy, in 2008, and compl...
The role of calcium channels in prostate cancer progression and potential as a druggable target for prostate cancer treatment
Prostate cancer (PCa) is the most diagnosed malignancy among men in various parts of the world (Kimura and Egawa, 2018). I...
IL-32 and its paradoxical role in neoplasia
In 1992, the cytokine-like natural killer cell transcript 4 (NK4) was discovered, which was shown to be selectively expres...
Preoperative treatments in borderline resectable and locally advanced pancreatic cancer: Current evidence and new perspectives
Pancreatic cancer (PC) represents the seventh most common cause of death worldwide, the fourth in the most developed count...
LncRNAs and related molecular basis in malignant pleural mesothelioma: Challenges and potential
Malignant pleural mesothelioma (MPM) is a rare but invasive cancer, which mainly arises from mesothelial tissues of pleura...
Efficacy and safety of adjuvant EGFR TKI alone and in combination with chemotherapy for resected EGFR mutation-positive non-small cell lung cancer: A Bayesian network meta-analysis
Lung cancer is the primary cause of cancer mortality worldwide, accounting for 11.4% of all cancers diagnosed in 2020 and ...
Clinical and molecular overview of immunotherapeutic approaches for malignant skin melanoma: Past, present and future
Melanomas are malignant tumors formed by the uncontrolled proliferation of atypical and genetically mutated melanocytes (C...
Effects and Moderators of Exercise Medicine on Cardiometabolic Outcomes in Men With Prostate Cancer Previously or Currently Undergoing Androgen Deprivation Therapy: An Individual Patient Data Meta-analysis
Pedro Lopez, PhD, is a postdoctoral fellow at the Exercise Medicine Research Institute (Edith Cowan University, Western Au...
Nano based-oncolytic viruses for cancer therapy
Cancer is one of the world's largest health problems.Based on global demographic characteristics, the incidence of cancer ...
DOSE AND VOLUME DE-ESCALATION OF RADIOTHERAPY IN HEAD AND NECK CANCER
Dr. Maria Jesus Garcia Anaya is currently a staff member in the Department of Radiation Oncology at the University Hospita...
Recent Advances and Research Progress in Biomarkers for Chronic Graft Versus Host Disease
Chronic graft versus host disease (cGVHD) is a major cause of nonrelapse morbidity and mortality and occurs in approximate...
Thrombosis and cachexia in cancer: two partners in crime?
Cancer is a prominent cause of mortality and a significant obstacle to improving life expectancy. Worldwide, the tumour ty...
“A Review of HER2 overexpression and somatic mutations in cancers”
Human Epidermal Growth Factor Receptor 2 (HER2) is a gene that encodes a growth factor receptor, which activates intracell...
Use of tumour bed boost radiotherapy in volume replacement oncoplastic breast surgery: A systematic review
Icro Meattini is Associate Professor at the Department of Clinical and Experimental Biomedical Sciences of the University ...
Late effects of childhood cancer survivors in Africa: A scoping review
Gertjan Kaspers is pediatric oncologist, professor at Amsterdam UMC and director Academy & Outreach at Princess Máxima...
Induction chemotherapy in locally advanced head and neck cancers, is there a best choice?
Hoda Mahdavi is an assistant professor in radiation oncology, and a medical educator of Iran University of Medical Science...
Current status of locally advanced rectal cancer therapy and future prospects
Colorectal cancer (CRC) is the third most commonly diagnosed malignancy. It accounts for more than 50,000 deaths annually ...
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