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The Seventeenth International Conference on Endothelin (ET-17)
The Seventeenth International Conference on Endothelin (ET-17)
The Seventeenth International Conference on Endothelin (ET-17) was held during 4–7 October 2021 and because of the SARS-Co...
Cardiodiabetology: newer pharmacologic strategies for reducing cardiovascular disease risks
Cardiodiabetology: newer pharmacologic strategies for reducing cardiovascular disease risks
Globally, nearly 500 million adults currently have diabetes, which is expected to increase to approximately 700 million by...
Effect of 4-hydroxychalcone as preventive and curative treatment in Wistar rats with liver injury
Effect of 4-hydroxychalcone as preventive and curative treatment in Wistar rats with liver injury
The increasing prevalence and complications related to liver diseases (caused by infection, toxic agents, or metabolic syn...
Endothelin-1 alters BMP signaling to promote proliferation of pulmonary artery smooth muscle cells
Endothelin-1 alters BMP signaling to promote proliferation of pulmonary artery smooth muscle cells
Pulmonary arterial hypertension (PAH) is characterized by abnormal outgrowth of pulmonary artery smooth muscle cells (PASM...
Role of phospholipase C in catecholamine-induced increase in myocardial protein synthesis
Role of phospholipase C in catecholamine-induced increase in myocardial protein synthesis
The activation of the α1-adrenoceptor-(α1-AR) by norepinephrine results in the G-protein (Gqα) mediated increase in the ph...
Endurance training-induced cardiac remodeling in a guinea pig athlete's heart model
Endurance training-induced cardiac remodeling in a guinea pig athlete's heart model
Besides the health benefits of regular exercise, high-level training—above an optimal level—may have adverse effects. In t...
Oxygen sensor of the heart
Oxygen sensor of the heart
How oxygen is sensed by the heart and what mechanisms mediate its sensing remain poorly understood. As recent reports show...
Opioid receptor μ, not δ and κ, modulate food intake induced by ghrelin in laying chickens
Opioid receptor μ, not δ and κ, modulate food intake induced by ghrelin in laying chickens
Evidence from animal studies suggests that the opioidergic system and ghrelin have a regulatory role in food intake, but t...
Hemostasis and oxidative stress in chronic kidney disease in children and adolescents
Hemostasis and oxidative stress in chronic kidney disease in children and adolescents
Chronic kidney disease (CKD) can be defined as the progressive loss of renal function, characterized by a decreased glomer...
Innate and adaptive immune cells associate with arteriovenous fistula maturation and failure
Innate and adaptive immune cells associate with arteriovenous fistula maturation and failure
Creation of arteriovenous fistula (AVF) causes local injury, resulting in immune response of the body and infiltration of ...
The loss of endothelin-2 exhibits an anticancer effect in A549 human lung adenocarcinoma cell line
The loss of endothelin-2 exhibits an anticancer effect in A549 human lung adenocarcinoma cell line
Lung cancer is the leading cause of cancer-related deaths worldwide, and adenocarcinoma is the most common subtype of lung...
Future scope and challenges for congestive heart failure: moving toward development of pharmacotherapy
Future scope and challenges for congestive heart failure: moving toward development of pharmacotherapy
Heart failure is invariably associated with cardiac hypertrophy and impaired cardiac performance. Although several drugs h...
Anti-cancer potential of cannabis terpenes in a Taxol-resistant model of breast cancer
Anti-cancer potential of cannabis terpenes in a Taxol-resistant model of breast cancer
Chemotherapeutic resistance can limit breast cancer outcomes; therefore, the exploration of novel therapeutic options is w...
Endothelin antagonism reduces hemoglobin A1c in patients with pulmonary hypertension
Endothelin antagonism reduces hemoglobin A1c in patients with pulmonary hypertension
Our lab recently reported that the blockade of endothelin-1 (ET-1) receptors attenuates insulin resistance in obese mice; ...
Mechanism and effects of artesunate on the liver function of rats with type 1 diabetic periodontitis
Mechanism and effects of artesunate on the liver function of rats with type 1 diabetic periodontitis
Periodontitis is an inflammatory disease of the gums. Periodontitis in diabetic patients can aggravate insulin resistance;...