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Physiology-Based Indications to Improve Outcome of Awake Extracorporeal Membrane Oxygenation*
Physiology-Based Indications to Improve Outcome of Awake Extracorporeal Membrane Oxygenation*
Acute hypoxemic respiratory failure (AHRF) and its more severe form, acute respiratory distress syndrome (ARDS), imply a d...
Measuring Strain in the ICU*
Measuring Strain in the ICU*
What are our limits? The best team in the best hospital can reach a point where patients’ needs exceed the institution’s c...
Buprenorphine: Its Emerging Role as a Strategy to Reduce Full Opioid Agonist Use in the ICU*
Buprenorphine: Its Emerging Role as a Strategy to Reduce Full Opioid Agonist Use in the ICU*
Pain is common in critically ill adults at both rest and during procedures. Opioids have remained the analgesic mainstay i...
Seizures After Acute Subdural Hemorrhage: Call for More Monitoring*
Seizures After Acute Subdural Hemorrhage: Call for More Monitoring*
Departments of Neurology and Neurosurgery, David Geffen School of Medicine, UCLA, Los Angeles, CA. *See also ...
POSTCARDS from a SIESTA: Crossing the Translational and Generalizability Gap for Predictive Models of Acute Respiratory Distress Syndrome-Related Mortality*
POSTCARDS from a SIESTA: Crossing the Translational and Generalizability Gap for Predictive Models of Acute Respiratory Distress Syndrome-Related Mortality*
In this issue of Critical Care Medicine, the study by Villar et al (1) tests a new mortality prediction score in Spanish I...
Are We Ready for Biomarker-Guided Immune Modulation in Critical Care?*
Are We Ready for Biomarker-Guided Immune Modulation in Critical Care?*
1 Division of Critical Care Medicine, Department of Medicine, Western University, London, ON, Canada. 2 Depar...
Measuring Bundle Implementation Work Requires a Calibrated Scale*
Measuring Bundle Implementation Work Requires a Calibrated Scale*
Both authors: Pulmonary, Allergy and Critical Care Division, Department of Medicine, Perelman School of Medicine, U...
Climbing the Evidence Pyramid: Developing an Evidence-Based Approach to the Provision of Venovenous Extracorporeal Membrane Oxygenation*
Climbing the Evidence Pyramid: Developing an Evidence-Based Approach to the Provision of Venovenous Extracorporeal Membrane Oxygenation*
1 Department of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN...
Is It Time to Reconsider the Concept of “Salvage Therapy” in Refractory Shock?*
Is It Time to Reconsider the Concept of “Salvage Therapy” in Refractory Shock?*
Distributive shock is the most common form of circulatory failure and is characterized by a systemic arterial tone insuffi...
Trajectory After Tracheostomy: Sobering Data for Decision Makers*
Trajectory After Tracheostomy: Sobering Data for Decision Makers*
1 Department of Medicine, Jersey City Medical Center, Jersey City, NJ. 2 Critical Care Consult Service, Divis...
Harmonizing ICU Admission, Discharge, and Transfer Criteria to Improve Critical Care Capability
Harmonizing ICU Admission, Discharge, and Transfer Criteria to Improve Critical Care Capability
1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Maryland School of Medici...
Apples and Oranges—All ‘Vitamin C’ May Not Be Created Equal
Apples and Oranges—All ‘Vitamin C’ May Not Be Created Equal
1 Department of Intensive Care, Royal Adelaide Hospital, Adelaide, SA, Australia. 2 Preclinical Critical Care...
Immediate Fluid Bolus or Norepinephrine in Endotoxic Shock
Immediate Fluid Bolus or Norepinephrine in Endotoxic Shock
Cardiothoracic Anaesthesia Division, Department of Anaesthesiology and Critical Care, Jawaharlal Institute of Medic...
Practice Standards for the Use of Multimodality Neuromonitoring: A Delphi Consensus Process*
Practice Standards for the Use of Multimodality Neuromonitoring: A Delphi Consensus Process*
OBJECTIVES: To address areas in which there is no consensus for the technologies, effort, and tra
Does CytoSorb Pose Unique Challenges to Pooled Estimates in Meta-Analysis?*
Does CytoSorb Pose Unique Challenges to Pooled Estimates in Meta-Analysis?*
Systematic review and meta-analysis has transformed the way we interpret and apply evidence-based medicine (1). While nume...
Prone Positioning in Acute Respiratory Distress Syndrome: Don’t Stop Believing...*
Prone Positioning in Acute Respiratory Distress Syndrome: Don’t Stop Believing...*
All authors: Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, Department of Medicine, UC San D...
Lung and Diaphragm Protection During Mechanical Ventilation: Synchrony Matters*
Lung and Diaphragm Protection During Mechanical Ventilation: Synchrony Matters*
1 Departamento Ciencias de la Salud, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chil...
Prepare for the Next Surge, Not the Last One*
Prepare for the Next Surge, Not the Last One*
I write while sitting in an airport following a long and delayed cross-country flight, waiting for my misdirected luggage ...
Noninvasive Respiratory Support in Adult Patients With COVID-19: Current Role and Research Challenges*
Noninvasive Respiratory Support in Adult Patients With COVID-19: Current Role and Research Challenges*
1 Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. 2 Departm...
Primum Non Nocere: Time to Rethink Probiotic Therapy*
Primum Non Nocere: Time to Rethink Probiotic Therapy*
The human microbiome is a naturally diverse ecosystem of trillions of commensal bacteria. These bacteria outnumber human c...
Executive Summary: Guidelines for Evaluating New Fever in Adult Patients in the ICU
Executive Summary: Guidelines for Evaluating New Fever in Adult Patients in the ICU
1 Internal Medicine Services, National Institutes of Health Clinical Center, Bethesda, MD. 2 Clinical Pharmac...
Society of Critical Care Medicine and the Infectious Diseases Society of America Guidelines for Evaluating New Fever in Adult Patients in the ICU
Society of Critical Care Medicine and the Infectious Diseases Society of America Guidelines for Evaluating New Fever in Adult Patients in the ICU
RATIONALE: Fever is frequently an early indicator of infection and often requires rigorous diagno
Quality Improvement or Unintended Consequences?*
Quality Improvement or Unintended Consequences?*
Ongoing improvement in the quality of care is an important and essential goal for the healthcare system. Reporting of outc...
Running Wide Open: Strong Evidence for Bolus Fluids Selection in Pediatric Sepsis*
Running Wide Open: Strong Evidence for Bolus Fluids Selection in Pediatric Sepsis*
Scrutinizing long-established practices in medicine is foundational to the culture of continuous improvement, yet requires...
C5a-C5aR1 Axis Blockade in Patients With Severe COVID-19: Differences Between PANAMO and FORCE Study
C5a-C5aR1 Axis Blockade in Patients With Severe COVID-19: Differences Between PANAMO and FORCE Study
1 Department of Intensive Care Medicine, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands...
Unpacking Regionalization of Sepsis Care Using Hospital Capability Assessments*
Unpacking Regionalization of Sepsis Care Using Hospital Capability Assessments*
The theory of regionalized acute care seeks to align specific patients with hospitals that offer expertise and capabilitie...
An Important, Potentially Life-Threatening Cause of Acute Adult Disorders of Consciousness Is Missing From the Evaluation Done by Chang et al
An Important, Potentially Life-Threatening Cause of Acute Adult Disorders of Consciousness Is Missing From the Evaluation Done by Chang et al
1 CHU UCL Godinne Namur, UCL Louvain Medical School, Namur, Belgium. 2 ICU Brugmann University Hospital, ULB ...
Scientific Progress and a Diagnostic Dilemma*
Scientific Progress and a Diagnostic Dilemma*
1 Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, ...
Unraveling the Obesity Paradox in Sepsis Patients: Insights Into the Role of Body Composition and Adipose Distribution
Unraveling the Obesity Paradox in Sepsis Patients: Insights Into the Role of Body Composition and Adipose Distribution
1 Department of Critical-Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and...
The Omission of Double-Zero Events Has the Potential to Introduce Bias Into the Outcomes of a Meta-Analysis
The Omission of Double-Zero Events Has the Potential to Introduce Bias Into the Outcomes of a Meta-Analysis
1 Intensive Care Unit, Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, China. ...
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