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Prognostic and diagnostic roles of prolyl 4-hydroxylase subunit α members in breast cancer
Aim: We aimed to evaluate the diagnostic and prognostic values of P4HAs in breast cancer (BC) patients. Materials & me...
Osteopontin and galectin-3 as biomarkers of maladaptive right ventricular remodeling in pulmonary hypertension
Aim: This study assessed the utility of osteopontin (OPN) and galectin-3 (Gal-3) as biomarkers of maladaptive right ventri...
The potential of miR-499 plasmatic level as a biomarker of obstructive sleep apnea syndrome
Background: Obstructive sleep apnea syndrome (OSAS) is one of the most common sleep-related breathing disorders. The aim o...
Pre-analytical sample handling effects on blood cytokine levels: quality control of a COVID-19 biobank
Aim: We investigated the effect of pre-analytical sample handling variations on coronavirus disease 2019-relevant circulat...
Novel kidney injury biomarkers in a large cohort of children with sickle cell anemia
Aim: The aim of this study was to compare novel kidney injury biomarkers in sickle cell anemia (SCA) children with and wit...
Increased levels of circulating circular RNA (hsa_circ_0013587) may serve as a novel biomarker for pancreatic cancer
Aim: Circular RNA can serve as a biomarker for early diagnosis of pancreatic cancer. Materials & methods: Analyzed the...
Lymphocyte-to-monocyte ratio predicts survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
Aim: Lymphocyte-to-monocyte ratio (LMR) predicts overall survival (OS) in patients with colorectal cancer. We explored LMR...
Predictive value of circulating sex hormone-binding globulin for gestational diabetes: a meta-analysis
Aim: To detect predictive value of preconception or early pregnancy sex hormone-binding globulin (SHBG) for subsequent ges...
Associations between serum lipids and mannose levels in coronary artery disease among nondiabetic patients
Aim: Nondiabetic patients have been studied to determine whether modest elevations in plasma mannose levels may be associa...
Breast invasive ductal carcinoma diagnosis with a three-miRNA panel in serum
Aim: Breast cancer, especially invasive ductal carcinoma (IDC), is the cause of a great clinical burden. miRNA could be co...
National Early Warning Score 2 and laboratory predictors correlate with clinical deterioration in hospitalized patients with COVID-19
Aim: We aimed to determine the prognostic values of the National Early Warning Score 2 (NEWS2) and laboratory parameters d...
Ceruloplasmin expression in renal cell carcinoma correlates with higher-grade and shortened survival
Aim: We aimed to explore ceruloplasmin (CP) expression in clear cell renal cell carcinoma (ccRCC). Materials & methods...
Novel molecular biomarkers and diagnosis of acute appendicitis in children
Reliable and efficient diagnosis of pediatric appendicitis is essential for the establishment of a clinical management pla...
Sialic acid as a potential biomarker for cardiovascular disease, diabetes and cancer
Cardiovascular disease (CVD), diabetes and cancer pose increasing global healthcare burdens. New biomarkers could enable e...
Predicting long-term cardiovascular outcomes in myocardial infarction survivors using multiple biomarkers
Aim: Although there are short- and long-term prognostic studies in patients with myocardial infarction (MI), the data that...
Urinary iodine concentration and radioactive iodine therapeutic response in patients with differentiated thyroid cancer
Aim: Urinary iodine concentration (UIC) may assess radioactive iodine ablation. Materials & methods: According the 201...
Computational analysis of MRIs predicts osteosarcoma chemoresponsiveness
Aim: This study aimed to improve osteosarcoma chemoresponsiveness prediction by optimization of computational analysis of ...
High expression of DNAJA1 (HDJ2) predicts unfavorable survival outcomes in breast cancer
Aim: DNAJA1 is associated with several cancers, but its biomarker potential in breast cancer is not adequately known. Mate...
Association between the rs3733846 in the flanking region of miR-143/145 and risk of cervical squamous cell carcinoma
Aim: To investigate the effect of rs3733846 in the flanking region of miR-143/145 on susceptibility to cervical squamous c...
Low miR-1231 expression predicts poor prognosis in non-small-cell lung cancer and accelerates cell proliferation, migration and invasion
Aim: miRNAs have been found to be involved in the tumor progression. This study aimed to assess the prognostic significanc...
AKP and GGT level can provide an early prediction of first-line treatment efficacy in colorectal cancer patients with hepatic metastases
Aim: It is important to early evaluate or predict the efficacy to avoid ineffective treatment for most colorectal cancer (...
Translation of a circulating miRNA signature of melanoma into a solid tissue assay to improve diagnostic accuracy and precision
Aim: Successful treatment of cutaneous melanoma depends on early and accurate diagnosis of clinically suspicious melanocyt...
Correlation of autophagy-related genes for predicting clinical prognosis in colorectal cancer
Aim: Autophagy plays a controversial role in cancer. The role of autophagy-related genes (ARGs) in colorectal cancer (CRC)...
Screening for regenerative therapy responders in heart failure
Risk of outcome variability challenges therapeutic innovation. Selection of the most suitable candidates is predicated on ...
Panitumumab and cetuximab affect differently miRNA expression in colorectal cancer cells
Structured abstract Background & aim: Resistance to anti-EGFR monoclonal antibodies in metastatic colorectal cancer (C...
Investigating ADAMTS7 and ADAMTS12 levels in prediabetic and Type 2 diabetic patients
Background: This study aims to investigate the role of ADAMTS7 and ADAMTS12 on atherosclerosis and inflammation in prediab...
AKP and GGT level can provide early prediction of first-line treatment efficacy in colorectal cancer patients with hepatic metastases
Aim: It is important to early evaluate or predict the efficacy to avoid ineffective treatment for most colorectal cancer (...
Systemic immune–inflammation index predicts new onset atrial fibrillation after ST elevation myocardial infarction
Aim: To investigate the predictive capacity of a systemic immune–inflammation index (SII) in detecting new onset atrial fi...