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Hematopoietic differentiation at single-cell resolution in NPM1-mutated AML
Hematopoietic differentiation at single-cell resolution in NPM1-mutated AML
Mason EF, Hasserjian RP, Aggarwal N, Seegmiller AC, Pozdnyakova O. Blast phenotype and comutations in acute myeloid leukem...
I-OPen: inferior outcomes of penta-refractory compared to penta-exposed multiple myeloma patients
I-OPen: inferior outcomes of penta-refractory compared to penta-exposed multiple myeloma patients
Multiple myeloma (MM) is a clinically and biologically heterogeneous malignancy characterized by structural and numerical ...
The prognostic value of the MASS in a multi-center cohort of patients with newly diagnosed multiple myeloma
The prognostic value of the MASS in a multi-center cohort of patients with newly diagnosed multiple myeloma
Multiple myeloma (MM) emerges as a heterogeneous disease with a considerable diversity in tumor biology, ...
Defining new reference intervals for serum free light chains in individuals with chronic kidney disease: Results of the iStopMM study
Defining new reference intervals for serum free light chains in individuals with chronic kidney disease: Results of the iStopMM study
Serum free light chain (FLC) concentration is greatly affected by kidney function. Using a large prospective population-ba...
Iopofosine I-131 treatment in late-line patients with relapsed/refractory multiple myeloma post anti-BCMA immunotherapy
Kazandjian D. Multiple myeloma epidemiology and survival: a unique malignancy. Semin Oncol. 2016;43:676–81.Article  ...
High response rates with single-agent belantamab mafodotin in relapsed systemic AL amyloidosis
High response rates with single-agent belantamab mafodotin in relapsed systemic AL amyloidosis
Eleven patients were included (eight male, three female). Baseline characteristics and responses are illustrated in Table ...
Smoldering multiple myeloma current treatment algorithms
Smoldering multiple myeloma current treatment algorithms
Smoldering multiple myeloma (SMM) is an asymptomatic condition that occupies a space between monoclonal gammopathy of unde...
Two-drug versus three-drug induction chemotherapy in pediatric acute myeloid leukemia: a randomized controlled trial
Two-drug versus three-drug induction chemotherapy in pediatric acute myeloid leukemia: a randomized controlled trial
The benefit of three-drug induction chemotherapy over a two-drug induction has not been evaluated in pediatric acute myelo...
Determining drug dose in the era of targeted therapies: playing it (un)safe?
Determining drug dose in the era of targeted therapies: playing it (un)safe?
Targeted therapies against phosphatidylinositol 3-kinase (PI3K), Bruton’s tyrosine kinase (BTK), and B-cell lymphoma...
Phenotypically-defined stages of leukemia arrest predict main driver mutations subgroups, and outcome in acute myeloid leukemia
Phenotypically-defined stages of leukemia arrest predict main driver mutations subgroups, and outcome in acute myeloid leukemia
Classifications of acute myeloid leukemia (AML) patients rely on morphologic, cytogenetic, and molecular features. Here we...
Myeloma precursor disease (MGUS) among rescue and recovery workers exposed to the World Trade Center disaster
Myeloma precursor disease (MGUS) among rescue and recovery workers exposed to the World Trade Center disaster
An elevated risk of myeloma precursor disease, monoclonal gammopathy of undetermined significance (MGUS), was identified a...
Differential prognostic impact of cytopenic phenotype in prefibrotic vs overt primary myelofibrosis
Differential prognostic impact of cytopenic phenotype in prefibrotic vs overt primary myelofibrosis
A CP was associated with older age, higher CD34 + cell count, higher prevalence of BM fibrosis grade 3, lower JAK2 mutant ...
Racial differences as predictors of outcomes in young patients with multiple myeloma
Racial differences as predictors of outcomes in young patients with multiple myeloma
In our institutional database, we identified 258 individuals who developed MM before age 50 (median age = 46; range: 17–50...
Predicting the outcome for patients with myelofibrosis undergoing an allogeneic hemopoietic stem cell transplant
Predicting the outcome for patients with myelofibrosis undergoing an allogeneic hemopoietic stem cell transplant
Cervantes F, Dupriez B, Pereira A, Passamonti F, Reilly JT, Morra E, et al. New prognostic scoring system for primary myel...
BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma
BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma
Bromodomain-containing protein 9 (BRD9), an essential component of the SWI/SNF chromatin remodeling complex termed ncBAF, ...
Long-term follow-up of cladribine treatment in hairy cell leukemia: 30-year experience in a multicentric Italian study
Long-term follow-up of cladribine treatment in hairy cell leukemia: 30-year experience in a multicentric Italian study
Hairy cell leukemia (HCL) is a rare lymphoproliferative disease with an excellent prognosis after treatment with cladribin...