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Dysregulation of insulin-like growth factor-1 signaling in postnatal bone elongation
Dysregulation of insulin-like growth factor-1 signaling in postnatal bone elongation
Insulin-like growth factor-1 (IGF-1) is a critical modulator of cell growth and survival, making it a central part of main...
Remembering the legacy of Professor Mohammad Hashemi: a pioneer in molecular genetic studies in southeast Iran (1965–2019)
Remembering the legacy of Professor Mohammad Hashemi: a pioneer in molecular genetic studies in southeast Iran (1965–2019)
Professor Mohammad Hashemi was a clinical biochemist and cancer genetic scientist. He has been chair and head of Departmen...
AKT1 participates in ferroptosis vulnerability by driving autophagic degradation of FTH1 in cisplatin-resistant ovarian cancer
AKT1 participates in ferroptosis vulnerability by driving autophagic degradation of FTH1 in cisplatin-resistant ovarian cancer
Resistance to cisplatin (DDP)-based chemotherapy is an important reason for the failure of ovarian cancer treatment. Howev...
Telomere biology and ribosome biogenesis: structural and functional interconnections
Telomere biology and ribosome biogenesis: structural and functional interconnections
Telomeres are nucleoprotein structures that play a pivotal role in the protection and maintenance of eukaryotic chromosome...
Mechanism of myocardial fibrosis regulation by IGF-1R in atrial fibrillation through the PI3K/Akt/FoxO3a pathway
Mechanism of myocardial fibrosis regulation by IGF-1R in atrial fibrillation through the PI3K/Akt/FoxO3a pathway
Atrial structural remodeling takes on a critical significance to the occurrence and maintenance of atrial fibrillation (AF...
Astrocyte-specific Ca2+ activity: Mechanisms of action, experimental tools, and roles in ethanol-induced dysfunction
Astrocyte-specific Ca2+ activity: Mechanisms of action, experimental tools, and roles in ethanol-induced dysfunction
Astrocytes are a subtype of non-neuronal glial cells that reside in the central nervous system. Astrocytes have extensive ...
Evaluation of biochemical profile and oxidative damage to lipids and proteins in patients with lysosomal acid lipase deficiency
Evaluation of biochemical profile and oxidative damage to lipids and proteins in patients with lysosomal acid lipase deficiency
Lysosomal acid lipase deficiency (LALD) is an inborn error of metabolism that lacks satisfactory treatment, which leads to...
Analysis of financial challenges faced by graduate students in Canada
Analysis of financial challenges faced by graduate students in Canada
Graduate students are vital to the creation of research and innovation in Canada. The National Graduate Student Finance Su...
Retraction: Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins
Retraction: Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins
© 2023 The Author(s). This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0), wh...
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an emerging pathogenic coronavirus, has been reported to cau...
High concentrations of fructose cause brain damage in mice
High concentrations of fructose cause brain damage in mice
Excessive fructose consumption is associated with the incidence of obesity and systemic inflammation, resulting in increas...
Mitogen- and stress-activated protein kinase (MSK1/2) regulated gene expression in normal and disease states
Mitogen- and stress-activated protein kinase (MSK1/2) regulated gene expression in normal and disease states
The mitogen- and stress-activated protein kinases (MSK) are epigenetic modifiers that regulate gene expression in normal a...
Structural features, intrinsic disorder, and modularity of a pyriform spidroin 1 core repetitive domain
Structural features, intrinsic disorder, and modularity of a pyriform spidroin 1 core repetitive domain
Orb-weaving spiders produce up to seven silk types, each with distinct biological roles, protein compositions, and mechani...
Retraction: Wnt5A regulates the expression of ROR2 tyrosine kinase receptor in ovarian cancer cells
Retraction: Wnt5A regulates the expression of ROR2 tyrosine kinase receptor in ovarian cancer cells
Hossein G., Arabzadeh S., Salehi-Dulabi Z., Dehghani-Ghobadi Z., Heidarian Y., Talebi-Juybari M. 2016. Wnt5A regulates the...
ERCC6 plays a promoting role in the progression of non-small cell lung cancer
ERCC6 plays a promoting role in the progression of non-small cell lung cancer
Although excision repair cross-complementing group 6 (ERCC6) has been reported to be associated with lung cancer risk, the...
Hedgehog signal activates AMPK via Smoothened to promote autophagy and lipid degradation in hepatocytes
Hedgehog signal activates AMPK via Smoothened to promote autophagy and lipid degradation in hepatocytes
Studies in the past decade have shown that lipid droplets stored in liver cells under starvation are encapsulated by autop...
Retraction: MicroRNA-181 inhibits proliferation and promotes apoptosis of chondrocytes in osteoarthritis by targeting PTEN
Retraction: MicroRNA-181 inhibits proliferation and promotes apoptosis of chondrocytes in osteoarthritis by targeting PTEN
© 2023 The Biochemistry and Cell Biology Editors. This work is licensed under a Creative Commons Attribution 4.0 Internati...
Retraction: Lentivirus-mediated angiopoietin-2 gene silencing decreases TNF-α induced apoptosis of alveolar epithelium cells
Retraction: Lentivirus-mediated angiopoietin-2 gene silencing decreases TNF-α induced apoptosis of alveolar epithelium cells
Sun N.-N., Li C., Zhou L., Peng Y., Zhang B., Qiu X.-M., et al. 2016. Lentivirus-mediated angiopoietin-2 gene silencing de...
Lipid-induced alteration in retinoic acid signaling leads to mitochondrial dysfunction in HepG2 and Huh7 cells
Lipid-induced alteration in retinoic acid signaling leads to mitochondrial dysfunction in HepG2 and Huh7 cells
A surfeit of mitochondrial reactive oxygen species (ROS) and inflammation serve as obligatory mediators of lipid-associate...
Maternal use of methamphetamine alters cardiovascular function in the adult offspring
Maternal use of methamphetamine alters cardiovascular function in the adult offspring
Methamphetamine is one of the most commonly used illicit drugs during pregnancy. Most studies investigating the impact of ...
Retraction: MiR-154 inhibits the growth of laryngeal squamous cell carcinoma by targeting GALNT7
Retraction: MiR-154 inhibits the growth of laryngeal squamous cell carcinoma by targeting GALNT7
© 2023 The Biochemistry and Cell Biology Editors. This work is licensed under a Creative Commons Attribution 4.0 Inter nat...
The nuclear receptor subfamily 4 group A1 in human disease
The nuclear receptor subfamily 4 group A1 in human disease
Nuclear receptor 4A1 (NR4A1), a member of the NR4A subfamily, acts as a gene regulator in a wide range of signaling pathwa...
Emerging roles for heterogeneous ribonuclear proteins in normal and malignant B cells
Emerging roles for heterogeneous ribonuclear proteins in normal and malignant B cells
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are among the most abundantly expressed RNA binding proteins in the cell...
RNA deadenylation complexes in development and diseases
RNA deadenylation complexes in development and diseases
RNA deadenylation, the process of shortening of the 3′ poly(A) tail of an RNA molecule, is one of the key steps of post-tr...
Epidermal melanocytes metabolize extracellular nucleotides by purinergic enzymes
Epidermal melanocytes metabolize extracellular nucleotides by purinergic enzymes
The human epidermal melanocyte (hEM) are melanin-producing cells that provide skin pigmentation and protection against ult...
GCN5 regulates ZBTB16 through acetylation, mediates osteogenic differentiation, and affects orthodontic tooth movement
GCN5 regulates ZBTB16 through acetylation, mediates osteogenic differentiation, and affects orthodontic tooth movement
In the process of orthodontic tooth movement (OTM), periodontal ligament fibroblasts (PDLFs) must undergo osteogenic diffe...
Effects of the omega-3 fatty acid DHA on histone and p53 acetylation in diffuse large B cell lymphoma
Effects of the omega-3 fatty acid DHA on histone and p53 acetylation in diffuse large B cell lymphoma
Diffuse large B cell lymphoma (DLBCL) often develops resistance and/or relapses in response to immunochemotherapy. Epigene...