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Extrusion-Based Three-Dimensional Printing of Metronidazole Immediate Release Tablets: Impact of Processing Parameters and in Vitro Evaluation
Extrusion-Based Three-Dimensional Printing of Metronidazole Immediate Release Tablets: Impact of Processing Parameters and in Vitro Evaluation
The current study assessed the potential of a pneumatic 3D printer in developing a taste-masked tablet in a single step. M...
Modelling of Prednisolone Drug Encapsulation in Poly Lactic-co-Glycolic Acid Polymer Carrier Using Molecular Dynamics Simulations
Modelling of Prednisolone Drug Encapsulation in Poly Lactic-co-Glycolic Acid Polymer Carrier Using Molecular Dynamics Simulations
Prednisolone, a synthetic corticosteroid drug, is extensively utilized to treat inflammatory diseases and regulates metabo...
Fused Deposition Modeling-Based 3D Printing as a Versatile Technology to Manufacture Vaginal Films Incorporating Metronidazole
Fused Deposition Modeling-Based 3D Printing as a Versatile Technology to Manufacture Vaginal Films Incorporating Metronidazole
Bacterial Vaginosis (BV), characterized by the overgrowth of pathogenic bacterial species in the female genital tract, is ...
Screening of Polysaccharide Films Consisting of pH-Dependent Systems in Combination with Microbial Decomposition-Dependent Systems to Determine the Appropriate Coating for Colonic Drug Delivery
Screening of Polysaccharide Films Consisting of pH-Dependent Systems in Combination with Microbial Decomposition-Dependent Systems to Determine the Appropriate Coating for Colonic Drug Delivery
The study aimed to identify a film sensitive to microbial decomposition to select an appropriate coating for delivering dr...
Physicochemical Interactions Between Concomitantly Administered Anti-Retroviral and Anti-Malarial Drug
Physicochemical Interactions Between Concomitantly Administered Anti-Retroviral and Anti-Malarial Drug
To investigate the physicochemical interactions between concomitantly administered anti-malarial and antiretroviral drugs....
Melt Granulation Techniques as an Alternative Manufacturing Technology for the Generic Development of Apixaban 5 mg Immediate-Release Tablets: A Case Study
Melt Granulation Techniques as an Alternative Manufacturing Technology for the Generic Development of Apixaban 5 mg Immediate-Release Tablets: A Case Study
Apixaban (APX) is a poorly soluble drug; hence, a micronized active pharmaceutical ingredient (API) is widely used for man...
Gastroprotective Efficacy of Prebiotic-based Oral Formulation of Amoxicillin
Gastroprotective Efficacy of Prebiotic-based Oral Formulation of Amoxicillin
Amoxicillin's side effects are due to its propensity to disturb gut flora. Prebiotics can aid in reversing the dysbios...
Sustained Release of Liposomal Caffeine Using Novel Natural Fiber Interlaced Liposomal Technology: Development and Structural Characterisation
Sustained Release of Liposomal Caffeine Using Novel Natural Fiber Interlaced Liposomal Technology: Development and Structural Characterisation
Caffeine is a naturally occurring central nervous system stimulant, susceptible to absorb faster in the body, and new desi...
Design and Critical Characterization the Pharmaceutical Cocrystal of Azelnidipine With Coformers for Boosting Physicochemical Properties
Design and Critical Characterization the Pharmaceutical Cocrystal of Azelnidipine With Coformers for Boosting Physicochemical Properties
Azelnidipine, a BCS class II antihypertensive medication, is known for its low solubility and high permeability. In order ...
Optimizing Nateglinide Liquisolid Compacts: Achieving Formulation Excellence Through the Quality by Design Approach
Optimizing Nateglinide Liquisolid Compacts: Achieving Formulation Excellence Through the Quality by Design Approach
The present study aimed to improve the dissolution properties of nateglinide, an anionic drug with poor water solubility a...
Quality by Design (QbD) Enabled and Central-Composite Design Assisted Approach for Formulation of Oral Herbal Gastro-retentive In-situ Gel
Quality by Design (QbD) Enabled and Central-Composite Design Assisted Approach for Formulation of Oral Herbal Gastro-retentive In-situ Gel
The delivery of herbal medications is currently a growing area in pharmacy. One of the areas of interest for the scientist...
Development and Implementation of a Comprehensive Initiative to Educate Healthcare Providers and Patients in the United States about the Risk of Drug-Drug Interactions Associated with Nirmatrelvir/ritonavir during the COVID-19 Pandemic
Development and Implementation of a Comprehensive Initiative to Educate Healthcare Providers and Patients in the United States about the Risk of Drug-Drug Interactions Associated with Nirmatrelvir/ritonavir during the COVID-19 Pandemic
This case study describes the development of a comprehensive drug-drug interaction (DDI) education initiative for nirmatre...
Ensuring Product Safety: A Comprehensive Retrospective Study of USFDA Drug Recalls (2019–2023)
Ensuring Product Safety: A Comprehensive Retrospective Study of USFDA Drug Recalls (2019–2023)
Despite stringent regulations enforced by the United States Food and Drug Administration (USFDA), numerous drug products s...
Targeting Cancer with Sweet Precision: Saccharide-Grafted Erlotinib for Enhanced Drug Delivery
Targeting Cancer with Sweet Precision: Saccharide-Grafted Erlotinib for Enhanced Drug Delivery
This study aims to enhance the targeting of erlotinib by grafting saccharides—galactose, pectin, and chitosan via ox...
Improving Continuous Loss-in-weight Feeding Accuracy by a Novel Hopper Design
Improving Continuous Loss-in-weight Feeding Accuracy by a Novel Hopper Design
Powder feeding is a vital unit operation in the continuous manufacturing of pharmaceutical products. Loss-in-weight twin-s...
Improving the Doxorubicin Loading to PLGA Nanoparticles with TOPSIS-Based Taguchi Design Approach: Effect of the Water Phase
Improving the Doxorubicin Loading to PLGA Nanoparticles with TOPSIS-Based Taguchi Design Approach: Effect of the Water Phase
PLGA nanoparticles are one of the most investigated drug delivery systems among all polymeric nanoparticles. Although ther...
Preparation and Characterization of Electrospun Polyvinylpyrrolidone Nanofiber Mat Containing Phillyrea Latifolia L. Herbal Extract and Evaluation of Antioxidant Mechanism
Preparation and Characterization of Electrospun Polyvinylpyrrolidone Nanofiber Mat Containing Phillyrea Latifolia L. Herbal Extract and Evaluation of Antioxidant Mechanism
Fast-disintegrating dosage forms based on nanofibers hold promise as effective carriers for a diverse array of drugs. In t...
Development and In-Vitro Characterization of Capsaicin Microsponges Loaded Topical Gels for Management of Arthritis
Development and In-Vitro Characterization of Capsaicin Microsponges Loaded Topical Gels for Management of Arthritis
Arthritis is the one of the leading causes of disability among a large group of population. It is a slowly progressive dis...
Accelerated Approval for Cancer Drugs in the United States and the Clinical Evidence Required for Conversion to Regular Approval
Accelerated Approval for Cancer Drugs in the United States and the Clinical Evidence Required for Conversion to Regular Approval
Oncology products often leverage accelerated approval program to seek earlier launches in the United States. Little is kno...
Assessment of the HaLCon® Protein Analyzer for At-Line Titer Measurements in Biomanufacturing Applications
Assessment of the HaLCon® Protein Analyzer for At-Line Titer Measurements in Biomanufacturing Applications
With the increasing demand for intensified processes in biopharmaceutical manufacturing, there is a growing requirement fo...
Formulation, Evaluation and Optimization of Acitretin Loaded Transethosomes for the Management of Psoriasis
Formulation, Evaluation and Optimization of Acitretin Loaded Transethosomes for the Management of Psoriasis
Psoriasis is a chronic inflammatory skin disorder characterized by the development of red, scaly patches (National Psorias...
Formulation, Optimization and In Vitro Studies of Flutamide-loaded Nanostructured Lipid Carrier Based Oral Drug Delivery for Enhanced Anticancer Activity
Formulation, Optimization and In Vitro Studies of Flutamide-loaded Nanostructured Lipid Carrier Based Oral Drug Delivery for Enhanced Anticancer Activity
The purpose of this study was to formulate and evaluate nanostructured lipid carriers (NLCs) of the poorly water soluble a...
Insight into Binding and Interaction of Docking, Dynamics and Network Pharmacology to Explore the Target on Cancer Inhibitors
Insight into Binding and Interaction of Docking, Dynamics and Network Pharmacology to Explore the Target on Cancer Inhibitors
The bioefficacy of accessible chemical structures has been established, leading to some optimization to address these cons...
Increasing the Stability of Pellets Containing Lycopene by Using Dual-Coating
Increasing the Stability of Pellets Containing Lycopene by Using Dual-Coating
Lycopene (LYC) is a natural carotenoid, which has antioxidant, anti-inflammatory and anti-cancer properties. Nevertheless,...
Proactive Approaches to cGMP Compliance: Insights and Key Takeaways from USFDA Warning Letters to Pharmaceutical Industries Between 2019 and 2024
Proactive Approaches to cGMP Compliance: Insights and Key Takeaways from USFDA Warning Letters to Pharmaceutical Industries Between 2019 and 2024
This study aims to meticulously analyse the trends and recurrent challenges that emerge from Warning Letters (WLs) issued ...
Tailoring and Optimization of Nifedipine Controlled Release Organogel via Quality by Design Approach
Tailoring and Optimization of Nifedipine Controlled Release Organogel via Quality by Design Approach
The primary aim of this study was to optimize, characterize, and test a controlled-release organogel of nifedipine for ora...
Assessment of the Effect of Microneedle Pretreatment on Permeation of Hydrophilic and Hydrophobic Drugs Through Burn Eschar
Assessment of the Effect of Microneedle Pretreatment on Permeation of Hydrophilic and Hydrophobic Drugs Through Burn Eschar
Here, utilizing of microneedle roller as a physical enhancer of drug permeation through third-degree burn eschar has been ...
Improving Ampoule Opening Safety: An Exploratory Comparative Study on an Innovative Ampoule Opener
Improving Ampoule Opening Safety: An Exploratory Comparative Study on an Innovative Ampoule Opener
Ampoules are widely used in medical settings worldwide. However, there is a lack of research comparing the safety and effi...
Fluconazole-Niosome-Laden Contact Lens: A Promising Therapeutic Approach for Prolonged Ocular Delivery and Enhanced Antifungal Activity
Fluconazole-Niosome-Laden Contact Lens: A Promising Therapeutic Approach for Prolonged Ocular Delivery and Enhanced Antifungal Activity
Traditional routes of administration of fluconazole such as eye drops have a low therapeutic efficacy due to insufficient ...
Micelles-Encapsulated with Azithromycin and Ibuprofen for Synergistic Antibacterial at Different pH
Micelles-Encapsulated with Azithromycin and Ibuprofen for Synergistic Antibacterial at Different pH
To improve azithromycin’s antibacterial activity at different pH through combination therapy. Azithromycin- and ibup...
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