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Design of Abuse-Deterrent Formulations Using Various Types of Thermal Deformed Starch (TDS)
Design of Abuse-Deterrent Formulations Using Various Types of Thermal Deformed Starch (TDS)
In recent years, the problem of drug abuse has emerged and is becoming more serious. Drug abuse can be secretly and illega...
Development and Pharmaceutical Evaluation of Azelaic Acid and Vitamin E Oil-Based Nanoemulgel of Tacrolimus for Topical Application in Plaque Psoriasis
Development and Pharmaceutical Evaluation of Azelaic Acid and Vitamin E Oil-Based Nanoemulgel of Tacrolimus for Topical Application in Plaque Psoriasis
Psoriasis is characterized by moisture- and lipid-deficient skin with an elevated epidermal keratinocyte hyperproliferatio...
New Insight into Acidifier-Induced Enhancement of Dissolution of Weakly Basic Drug, Dipyridamole
New Insight into Acidifier-Induced Enhancement of Dissolution of Weakly Basic Drug, Dipyridamole
Most studies regarding acidifiers focused on their role in improving the dissolution performance of a drug by altering the...
Para-Hydroxy Benzoic Acid Coformer Enable Enhanced Solubility, Dissolution, and Antifungal Activity of Ketoconazole Cocrystals
Para-Hydroxy Benzoic Acid Coformer Enable Enhanced Solubility, Dissolution, and Antifungal Activity of Ketoconazole Cocrystals
The present investigation was aimed at preparing ketoconazole cocrystals using phenolic acid coformers. The slow solvent e...
Synthesis and Anticancerogenic Effect of New Generation Ruthenium-Based Nanoparticle from Homalothecium sericeum with Eco-Friendly Method
Synthesis and Anticancerogenic Effect of New Generation Ruthenium-Based Nanoparticle from Homalothecium sericeum with Eco-Friendly Method
Green synthesis is a simple, inexpensive, and highly efficient method for the preparation of nanoparticles. In this study,...
Cross-Linked β-Cyclodextrin Based Nanosponges for Allyl Methyl Sulfide Delivery-Physicochemical Characterization and In Vitro Study
Cross-Linked β-Cyclodextrin Based Nanosponges for Allyl Methyl Sulfide Delivery-Physicochemical Characterization and In Vitro Study
Our work aims to cross-linked cyclodextrin-based nanosponges for allyl methyl sulfide delivery, physicochemical characteri...
Backgrounded Membrane Imaging—A Valuable Alternative for Particle Detection of Biotherapeutics?
Backgrounded Membrane Imaging—A Valuable Alternative for Particle Detection of Biotherapeutics?
The presence of visible and sub-visible particles is a critical quality attribute of biotherapeutics that needs to be moni...
Hydrogel-Forming Microarray Patches–Mediated Transdermal Delivery of Telmisartan from Polyethylene Glycol Reservoir
Hydrogel-Forming Microarray Patches–Mediated Transdermal Delivery of Telmisartan from Polyethylene Glycol Reservoir
In this study, we developed a transdermal delivery system of telmisartan to overcome its shortcomings through a hydrogel-f...
Gastroretentive Floating Microsponges of Mitiglinide: Design, Preparation, and Pharmacokinetic Evaluation
Gastroretentive Floating Microsponges of Mitiglinide: Design, Preparation, and Pharmacokinetic Evaluation
Gastroretentive floating microsponges are interesting because they remain buoyant for a long time and release the drug gra...
Lipid Complex-Itraconazole in Thermosensitive Mucoadhesive Vaginal Gel to Enhance the Effectiveness of Therapy for Vulvovaginal Candidiasis: Formulation, Optimization, Characterization, and Ex vivo Evaluation
Lipid Complex-Itraconazole in Thermosensitive Mucoadhesive Vaginal Gel to Enhance the Effectiveness of Therapy for Vulvovaginal Candidiasis: Formulation, Optimization, Characterization, and Ex vivo Evaluation
This study aimed to produce lipid complex-ITR (CL-ITR) to enhance the solubility of ITR which is then made into an in situ...
Mucoadhesive Films of Docetaxel with Ceramide as an Adjuvant Monitoring Polymer-Drug Partitioning for Optimal Drug Release
Mucoadhesive Films of Docetaxel with Ceramide as an Adjuvant Monitoring Polymer-Drug Partitioning for Optimal Drug Release
Millions of individuals worldwide are affected by cancer, with increasing instances by 1% annually and strikingly high mor...
Polyoxyethylene Lauryl Ether (Brij-35) and Poloxamer 407–Based Non-ionic Surfactant Vesicles for Dissolution Enhancement of Tacrolimus
Polyoxyethylene Lauryl Ether (Brij-35) and Poloxamer 407–Based Non-ionic Surfactant Vesicles for Dissolution Enhancement of Tacrolimus
This study aimed to develop niosomes using polyoxyethylene lauryl ether (Brij-35) and poloxamer 407 surfactants for dissol...
Development and Characterization of Soy Lecithin Liposome as Potential Drug Carrier Systems for Doxorubicin
Development and Characterization of Soy Lecithin Liposome as Potential Drug Carrier Systems for Doxorubicin
The phospholipids from plant origins play an important role in different techniques, especially in drug delivery applicati...
Study of the Bacteria Location in a Closed Chamber for Their Inactivation by High Ozone Concentration
Study of the Bacteria Location in a Closed Chamber for Their Inactivation by High Ozone Concentration
This paper is aimed to an experimental study carried out on a new sterilization technique with gaseous ozone produced insi...
Passive Targeted Drug Delivery of Venlafaxine HCl to the Brain by Modified Chitosan Nanoparticles: Characterization, Cellular Safety Assessment, and In Vivo Evaluation
Passive Targeted Drug Delivery of Venlafaxine HCl to the Brain by Modified Chitosan Nanoparticles: Characterization, Cellular Safety Assessment, and In Vivo Evaluation
Generalized anxiety is one of the most frequent anxiety problems. This study aimed to improve the distribution of venlafax...
Enhancing Solubility and Dissolution Behavior of Finasteride Using Solid Dispersion Technique by Carrier Screening and the New Preparation Instrument
Enhancing Solubility and Dissolution Behavior of Finasteride Using Solid Dispersion Technique by Carrier Screening and the New Preparation Instrument
The purpose of this study was to improve the solubility and dissolution rate of finasteride (FIN) by searching for an opti...
Effect of Active Pharmaceutical Ingredient, Lipid Composition, and Thermal Processing on the Physical Stability of Local Anesthetic-loaded Lipid Microparticles
Effect of Active Pharmaceutical Ingredient, Lipid Composition, and Thermal Processing on the Physical Stability of Local Anesthetic-loaded Lipid Microparticles
This study investigates the effects of heat annealing, drug, and lipid composition on the physical stability of solid lipi...
Using of Oxygen Species in the Sterilization of Medical Equipment and Assessment of the Test Results
Using of Oxygen Species in the Sterilization of Medical Equipment and Assessment of the Test Results
Medical equipment used in the health sector require complete sterilization to protect patients from infection. This study ...
A Quality by Design Paradigm for Albumin-Based Nanoparticles: Formulation Optimization and Enhancement of the Antitumor Activity
A Quality by Design Paradigm for Albumin-Based Nanoparticles: Formulation Optimization and Enhancement of the Antitumor Activity
Albumin nanoparticles are promising carriers for therapeutic agents, owing to their biocompatibility, safety, and versatil...
Design of a Production Planning System in a Pharmaceutical Factory: Spreadsheet Model and Case Study
Design of a Production Planning System in a Pharmaceutical Factory: Spreadsheet Model and Case Study
This work focuses on developing a production planning tool for small- and medium-sized enterprises (SMEs) in pharmaceutica...
Residence Time Distribution-Based Smith Predictor: an Advanced Feedback Control for Dead Time–Dominated Continuous Powder Blending Process
Residence Time Distribution-Based Smith Predictor: an Advanced Feedback Control for Dead Time–Dominated Continuous Powder Blending Process
In continuous manufacturing (CM), the material traceability and process dynamics can be investigated by residence time dis...
Development of a Statistical Approach for Microbial Monitoring in Non-sterile Pharmaceutical Environments
Development of a Statistical Approach for Microbial Monitoring in Non-sterile Pharmaceutical Environments
Little attention has generally been given to non-sterile pharmaceutical manufacturing, because these products represent le...
Development and in Vitro/In Vivo Evaluation of Itopride Hydrochloride Expanding Tablets
Development and in Vitro/In Vivo Evaluation of Itopride Hydrochloride Expanding Tablets
Gastroretentive drug delivery systems (GRDDS) have attracted interest for enhancement of absorption and bioavailability of...
Application of Amorphous Solid Dispersion Technology for Improving the Physicochemical Properties, Saturation Solubility, and In Vitro Dissolution of Withania somnifera Methanolic Root Powder Extract
Application of Amorphous Solid Dispersion Technology for Improving the Physicochemical Properties, Saturation Solubility, and In Vitro Dissolution of Withania somnifera Methanolic Root Powder Extract
Withania somnifera is a xerophytic plant whose methanolic extract of root powder has exhibited effectiveness against vario...
Editorial: Biologics and Parenterals: Major Newsmakers
Editorial: Biologics and Parenterals: Major Newsmakers
Dear Readers of the Journal of Pharmaceutical Innovation:It seems that when one opens a pharm...
Development, Optimization and In Vitro Characterization of Eudragit-Ganciclovir Nanosuspension or Treating Herpes Simplex Keratitis
Development, Optimization and In Vitro Characterization of Eudragit-Ganciclovir Nanosuspension or Treating Herpes Simplex Keratitis
In the present study, we aimed to optimize, formulate and characterize Eudragit-based nanosuspension of Ganciclovir (GCV-N...
Mucoadhesive Oro-Gel–Containing Chitosan Lipidic Nanoparticles for the Management of Oral Squamous Cell Carcinoma
Mucoadhesive Oro-Gel–Containing Chitosan Lipidic Nanoparticles for the Management of Oral Squamous Cell Carcinoma
The aim of this research work was to develop a mucoadhesive oro-gel–containing resveratrol loaded folate conjugated ...
Solubility Enhancement of Aripiprazole via Mesoporous Silica: Preparation, Characterization, In vitro Drug Release, and Solubility Determination
Solubility Enhancement of Aripiprazole via Mesoporous Silica: Preparation, Characterization, In vitro Drug Release, and Solubility Determination
Hollow types of mesoporous silica have been extensively used as drug delivery carriers owing to their excessive drug loadi...
QbD Enabled Formulation Development of Nanoemulsion of Nimodipine for Improved Biopharmaceutical Performance
QbD Enabled Formulation Development of Nanoemulsion of Nimodipine for Improved Biopharmaceutical Performance
The objective of the current research is to formulate a nanoemulsion (NE) of nimodipine (ND) to improve its oral bioavaila...
Nanospanlastics as a Novel Approach for Improving the Oral Delivery of Resveratrol in Lipopolysaccharide-Induced Endotoxicity in Mice
Nanospanlastics as a Novel Approach for Improving the Oral Delivery of Resveratrol in Lipopolysaccharide-Induced Endotoxicity in Mice
Resveratrol (RSV) is a natural polyphenolic compound that has numerous biological effects. Owing to its poor bioavailabili...
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