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Synthesis and applications of the sulfur containing analogues of cyclic carbonates
Cyclic thiocarbonates are the sulfur containing analogues of the well-studied cyclic carbonates and are relatively poorly ...
Chiral sulfide and selenide catalysts for asymmetric halocyclizations and related reactions
Asymmetric organocatalysis using well-designed artificial chiral molecular catalysts is one of the most reliable methods t...
Chiral phosphoric acid-catalyzed Friedel-Crafts reaction of 2,5-disubstituted and 2-monosubstituted pyrroles with isoindolinone-derived ketimines
Enantioselective reaction between 2,5-disubstituted pyrroles and diaryl-ketimines, generated in situ from isoindolinone-de...
A Structure Activity Relationship Study of 3,4’-Dimethoxyflavone for ArlRS Inhibition in Staphylococcus aureus
Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are difficult to treat due to their resistance to ...
Kinetic resolution of sulfoxides with high enantioselectivity by a new homologue of methionine sulfoxide reductase B
Optically pure sulfoxides are noteworthy compounds that find wide applications in various industrial fields. Here we repor...
Copper-catalyzed radical-mediated intermolecular cyanomonofluoroalkylation of alkenes and alkynes
A novel copper-catalyzed three-component reaction of monofluoroalkylation agents, alkenes and TMSCN is described. In addit...
Deoxygenation of oximes for the synthesis of pyrrolines via hydroimination cyclization
Herein, we report the generation of iminyl radicals through photocatalytic deoxygenation of oximes with trivalent phosphin...
Nickel-catalyzed reductive coupling of arylcarboxylic acid 2-pyridyl esters with alkyl methanesulfonates: access to alkyl aryl ketones
Alkyl aryl ketones were synthesized via nickel-catalyzed reductive coupling reaction of arylcarboxylic acid (2-pyridyl)est...
Hydrogen Bond Directed High Fidelity Optical Detection of Picric Acid: Single Driver through Diverse Road towards Same Destiny
High-fidelity optical detection of picric acid is the urge of the time due to its toxic and explosive nature. Moreover, Pi...
Synthesis, conformational stability and molecular structure of 4-aryl- and 4,5-diaryl-1,8-bis(dimethylamino)naphthalenes
4-Bromo- and 4,5-dibromo-1,8-bis(dimethylamino)naphthalenes were arylated with arylboronic acids under Suzuki reaction con...
From Oximes to Tertiary Alcohols in Water, at Room Temperature in Air: Hybrid One-pot Tandem Assembly of Enzymatic Deoximation and RLi/RMgX Reagents
The highly efficient biodeoximation of aromatic ketoximes, promoted by the enzymatic oxidative system laccase/TEMPO/O2 has...
Photocatalytic synthesis of azaheterocycle-fused piperidines and pyrrolidines via tandem difunctionalization of unactivated alkenes
A variety of azaheterocycle-fused piperidines and pyrrolidines bearing CF3 and CHF2 functionalities were achieved using CF...
Correction: An asymmetric metal-templated route to amino acids with an isoquinolone core via a Rh(III)-catalyzed coupling of aryl hydroxamates with chiral propargylglycine Ni(II) complexes
Correction for ‘An asymmetric metal-templated route to amino acids with an isoquinolone core via a Rh(iii)-catalyzed coupl...
Synthesis of Quinazolinones via Cp*Co(III)-Catalyzed C-H Functionalization of Primary Amides with Oxadiazolones
Multi-heteroatom heterocycle synthesis through direct C-H bond activation is methodologically appealing but synthetically ...
Kinetic analysis for highly effective triplex formation between small molecule-peptide nucleic acid conjugate probe and Influenza A virus RNA promoter region at neutral pH
In order to overcome pH limitations of triplex-forming peptide nucleic acid (PNA) for the binding to double-stranded RNA (...
Catalytic Aminomethylative Etherification of N-Allenamides with N,O-Acetals Enabled by Lewis/Brønsted Acid Catalysis
A novel copper-catalyzed aminomethylative etherification of N-allenamides/ alkoxyallenes with N,O-acetals have been realiz...
Formal Synthesis of Cyclotheonellazole A
A convergent procedure for the formal synthesis of cyclotheonellazole A has been developed with high yields and excellent ...
Cu(II)-catalyzed domino construction of spironaphthalenones by dearomatization of β-naphthols and using N, N-dimethylaminoethanol as a C1 synthon
Herein, a Cu(II)-catalyzed facile construction of synthetically valuable spiro compounds from β-Naphthols under air is rep...
Modular Synthesis of Fluorinated 2H-Thiophenes via [4+1] Cyclization of Enaminothiones
An efficient and straightforward synthetic method has been disclosed to construct trifluoromethyl 2H-thiophenes through [4...
Thia-Michael Addition: The Route to Promising Opportunities for Fast and Cysteine-Specific Modification
Over the last few decades, design and discovery of chemical reactions that enable modification of proteins at pre-determin...
Correction: An efficient metal free synthesis of 2-aminobenzothiozoles – a greener approach
Correction for ‘An efficient metal free synthesis of 2-aminobenzothiozoles – a greener approach’ by Krithika Ganesh et al....
Ru(II)-Catalyzed Oxidative Coupling of Sulfoxonium Ylides with Amines: Efficient Synthesis of α-Ketoamides and Indolo[2,1-a]isoquinolines
The first use of sulfoxonium ylides for the synthesis of α-ketoamides is described via Ru(II)-catalyzed amidation reaction...
Defluorinative Alkylation of 1-Trifluoromethyl Alkenes with Alkyl Radicals Derived from Visible-Light Induced Deoxygenation of Xanthate Salts: Synthesis of gem-Difluoroalkenes
Catalyst- and metal-free difluoroallylation of alkyl precursors with trifluoromethyl alkenes for the synthesis of gem-difl...
Nickel-Catalysed Enantioselective Reaction of Secondary Phosphine Oxides and Activated Vinylcyclopropanes
Activated vinylcyclopropanes (VCPs) can form zwitterionic π-allylmetal species in the presence of transition metals and ar...
Stabilizing the hydroperoxyflavin intermediate formation via peptide appendage: A neutral flavoenzyme model
A bioinspired mimic for the stabilization of hydroperoxyflavin intermediate formation was designed and investigated for th...
Synthesis of 1,2-diaminotruxinic δ-cyclobutanes by BF3-controlled [2+2]-photocycloaddition of 5(4H)-oxazolones. Stereoselective expansion of δ-cyclobutanes to give highly substituted pyrrolidine-2,5-dicarboxylates
The irradiation of (Z)-4-arylidene-5(4H)-oxazolones 1a-1u with blue light (465 nm) in presence of the photosensitizer [Ru(...
Synthesis and Ring-Opening Metathesis Polymerisation of O-Alkoxy Benzothiadiazole Paracyclophane-1,9-dienes
Ortho-diethylhexyloxyphenylene benzothiadiazole paracyclophane-1,9-diene as a mixture of diastereomers was synthesized by ...
Host-guest complexation of phthalimide-derived strigolactone mimics with cyclodextrins. Application in agriculture against parasitic weeds
Parasitic weeds are noxious plants that damage crops of economic relevance, especially in Mediterranean and African countr...
Factors influencing on-resin depsipeptide bond formation: Case studies on daptomycin- and brevicidine-derived sequences
Depsipeptides are an important class of bioactive natural products, where a growing number of genome-mined structures that...
Bimodal structural tuning of pyrrole-2-carboxamide-based transmembrane ion transport system
Pyrrole-2-carboxamide moiety is well known for its presence in various natural products and its use in anion receptor syst...
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