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Recent Advances in Green Multi-Component Reactions for Heterocyclic Compound Construction
Multi-component reactions (MCRs) are processes in which three or more reactants are introduced in one pot to deliver final...
Recent Progress on the Electro-Organic Synthesis for the 1,2-Difunctionalization of Alkenes
Recent years have witnessed significant achievements in electro-organic chemistry, particularly in the difunctionalization...
An efficient direct electrolysis method for the synthesis of 1,1,1,3,3,3-hexafluoroisopropyxy substituted imidazo[1,2-a]pyridines
Electrochemical oxidative cross-dehydrogenative-coupling (CDC) is an ideal strategy to develop C3-alkoxylation of imidazo[...
Disulfide Mediated Ruthenium Catalyzed Direct C-H Thiolation in Benzoxazinone Systems: Selective Synthesis of ortho-Thiolated 2- Arylbenzoxazinones
2-Arylbenzoxazinone undergoes direct ortho-C-H thiolation by using diaryl disulfide in presence of Ru(II)-phosphine cataly...
FeCl3-Catalyzed Oxidative Diselenylation of Pyrrole-tethered Indoles
A mild and efficient FeCl3-catalyzed oxidative diselenylation of pyrrole-tethered indoles has been reached by using RSeSeR...
Bromide-promoted cascade annulation of isocyanobiaryls with aldehydes through photoredox catalysis
Herein, we report a cascade annulation of readily available isocyanobiaryls with simple aldehydes via photoredox catalysis...
Atmospheric Oxygen Mediated Oxidation Coupling of Primary and Secondary Alcohols: Synthesis of Pyrazolo[1,5-a]pyrimidines
An atmospheric oxygen-mediated oxidative coupling of primary and secondary alcohols for the synthesis of nitrogen-containi...
Cross-coupling reaction of cyclic quaternary ammonium salts with arylzinc reagents, arylboron reagents, and silylboronate
The nickel-catalyzed reaction of benzocyclic quaternary ammonium salts with arylzinc reagents or arylboron reagents afford...
Unexpected amine-triggered skeletal modification of fascaplysin and its derivatives: a rapid access to δ, γ-biscarbolines
An unsuccessful attempt to directly construct alkaloid iheyamine A from fascaplysin framework resulted in the discovery of...
Ag(I)-Promoted fragment coupling of peptide thioamides
Despite advances in solid phase peptide synthesis and peptide ligation, challenges remain in the assembly of polypeptides ...
I2-Catalyzed Benzylation of NH-Sulfoximines with Diarylme-thanes and Al-kylarenes
A practical transition metal-free approach for the selective benzylation of NH-sulfoximines has been disclosed by using si...
High-yielding Total Synthesis of Embelin, Rapanone, and Irisoquin A, D, F
A simple and sustainable three- and four-step sequences of di-OH-protection/mono-OMe-deprotection/OrgRC and di-OH-protecti...
Regioselective synthesis of 5-azaindazoles based on the intramolecular amination reaction of 5-acyl-4-pyridones with hydrazines
The labile tautomerism of N-unsubstituted 5-acyl-4-pyridones, which exist in the form of 4-pyridone or 4-hydroxypyridine d...
Retraction: Thiourea dioxide promoted efficient organocatalytic one-pot synthesis of a library of novel heterocyclic compounds
Retraction of ‘Thiourea dioxide promoted efficient organocatalytic one-pot synthesis of a library of novel heterocyclic co...
Monoterpenoid Selenophenes Derived from (-)-Carvone with GPx-like activity
Organoselenium compounds have been recognized as potential therapeutic agents against several diseases. Specifically, the ...
Cp*Co(III)-catalyzed ortho-alkylation/alkenylation of anilides
A highly practical and efficient Cp*Co(III)-catalyzed C–H alkylation/alkenylation reaction of anilides with maleimides and...
Correction: A novel platinum(II) complex with a berberine derivative as a potential antitumor agent targeting G-quadruplex DNA
Correction for ‘A novel platinum(ii) complex with a berberine derivative as a potential antitumor agent targeting G-quadru...
Facile synthesis of the unknown 6,7-dihydrofuro[3,4-c]pyridines and 3,4-diaryloylpyridines from N-propargyl β-enaminones
In this paper, we have uncovered a new reaction of N-homopropargylic β-enaminones, i.e. N-(4-phenyl-3-butynyl)-β-enaminone...
Copper (I) Catalyzed Coupling of Alkynyl Glycosides: Synthesis of Buta 1,3-Diyne Linked Disaccharides and Dinucleosides
Herein we report copper-catalyzed coupling of alkynyl glycosides facilitating the synthesis of buta 1,3 diyne linked disac...
Direct Organocatalytic Chemoselective Synthesis of Pharmaceutically Active Benzothiazole/Benzoxazole-Triazoles
Benzothiazole and benzoxazole heterocyclic rings containing 1,4,5-trisubstituted-1,2,3-triazoles are well-known for their ...
A silicon rhodamine 1,2-dioxetane chemiluminophore for in vivo near-infrared imaging
Near-infrared (NIR) chemiluminescent probes have attracted increasing attention in recent years due to their attractive pr...
Preparation of Ethynylsulfonamides and Study of Their Reactivity with Nucleophilic Amino Acids
The development of covalent drugs, particularly those utilizing Michael acceptors, has garnered significant attention in r...
Halonium and Chalconium Salt-Catalyzed Schiff Condensation: Kinetics and DFT Insights into Organocatalyst Activity Parameters
Schiff condensation between 4-methylbenzaldehyde and 2-aminopyridine, catalyzed by chloronium, bromonium, iodonium triflat...
Recent Progress in C–S Bond Formation via Electron Donor-Acceptor Photoactivation
Recent advancements in C–S bond formation via electron donor-acceptor (EDA) photoactivation have been highlighted. EDA com...
Palladium-catalyzed allylic C-H alkylation of terminal olefins with 3-carboxamide oxindoles
A novel palladium-catalyzed allylic C-H alkylation of terminal olefins with 3-carboxamide oxindoles is described. A variet...
Photocatalyst-free formate-mediated C-O cleavage by EDA complex and SCS strategy for synthesis of diaryl 1,4-diketone in air
Under mild visible light conditions, formates facilitate C-O cleavage via the EDA complex and SCS strategy, yielding the α...
DNA-compatible one-pot synthesis of multi-substituted dihydrofuran via pyridinium ylide-mediated cyclization
Synthesis of chemically diverse heterocyclic scaffolds in DNA-encoded libraries is highly demanded. We herein reported a c...
Scalable Synthesis of (±)-Gregatin A via 1, 3-dipolar Cycloaddition Strategy
A 6-step gram-scale synthesis of fungal polyketide (±)-gregatin A was described. The synthetic route features an inte...
DBU-catalyzed annulation strategy for modular assembly of 2,3-difunctionalized dihydrobenzofurans
An organocatalytic approach for the construction of 2,3-dihydrobenzofuran scaffold through a formal [4+1] annulation of 2-...
Strain-promoted azide-alkyne cycloaddition enhanced by the secondary interactions†
Azide-alkyne cycloaddition of cyclooct-2-yn-1-ol and 2-(azidophenyl)boronic acid proceeded rapidly at room temperature wit...
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