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Using the global randomization test as a Mendelian randomization falsification test for the exclusion restriction assumption
Using the global randomization test as a Mendelian randomization falsification test for the exclusion restriction assumption
Mendelian randomization may give biased causal estimates if the instrument affects the outcome not solely via the exposure...
On the study of fetal growth restriction: time to abandon SGA
On the study of fetal growth restriction: time to abandon SGA
Wilcox AJ, Skjaerven R. Birth weight and perinatal mortality: the effect of gestational age. AJPH. 1992;82(3):378–82.Artic...
The Danish Nationwide Electrocardiogram (ECG) Cohort
The Danish Nationwide Electrocardiogram (ECG) Cohort
The electrocardiogram (ECG) is a non-invasive diagnostic tool holding significant clinical importance in the diagnosis and...
Antihypertensive drug targets and breast cancer risk: a two-sample Mendelian randomization study
Antihypertensive drug targets and breast cancer risk: a two-sample Mendelian randomization study
Findings on the correlation between the use of antihypertensive medication and the risk of breast cancer (BC) have been in...
Dimensions of health data Integrity
Dimensions of health data Integrity
Health data integrity, as an emergent concept, stands to reshape the lifecycle of data-driven healthcare and research, ens...
Does having siblings really protect against childhood atopic diseases? A total population and within-family analysis
Does having siblings really protect against childhood atopic diseases? A total population and within-family analysis
The association between having older siblings and decreased risk for atopic symptoms is well-established. This has been in...
The Rotterdam Study. Design update and major findings between 2020 and 2024
The Rotterdam Study. Design update and major findings between 2020 and 2024
The Rotterdam Study is a population-based cohort study, started in 1990 in the district of Ommoord in the city of Rotterda...
Occupational exposure to diesel exhausts and liver and pancreatic cancers: a systematic review and meta-analysis
Occupational exposure to diesel exhausts and liver and pancreatic cancers: a systematic review and meta-analysis
Diesel exhaust (DE) is human carcinogen with sufficient evidence only for lung cancer. Systematic evidence on other cancer...
Partial substitution of red meat or processed meat with plant-based foods and the risk of colorectal cancer
Partial substitution of red meat or processed meat with plant-based foods and the risk of colorectal cancer
Shifting from animal-based to plant-based diets could reduce colorectal cancer (CRC) incidence. Currently, the impacts of ...
Assessing the importance of primary care diagnoses in the UK Biobank
Assessing the importance of primary care diagnoses in the UK Biobank
The UK Biobank has made general practitioner (GP) data (censoring date 2016–2017) available for approximately 45% of...
Vitamin D and human health: evidence from Mendelian randomization studies
Vitamin D and human health: evidence from Mendelian randomization studies
We summarized the current evidence on vitamin D and major health outcomes from Mendelian randomization (MR) studies. PubMe...
Higher-order evidence
Higher-order evidence
Higher-order evidence is evidence about evidence. Epidemiologic examples of higher-order evidence include the settings whe...
Menopausal hormone therapy and risk of sarcoidosis: a population-based nested case–control study in Sweden
Menopausal hormone therapy and risk of sarcoidosis: a population-based nested case–control study in Sweden
Sarcoidosis incidence peaks in women between 50 and 60 years old, which coincides with menopause, suggesting that certain ...
Cohort profile: the China surgery and anesthesia cohort (CSAC)
Cohort profile: the China surgery and anesthesia cohort (CSAC)
The China Surgery and Anaesthesia Cohort (CSAC) study was launched in July 2020 and is an ongoing prospective cohort study...
A diet-wide association study for liver cancer risk: findings from a prospective cohort study in Chinese men
A diet-wide association study for liver cancer risk: findings from a prospective cohort study in Chinese men
Dietary factors have been extensively investigated as possible risk factors for liver cancer, but the evidence is inconclu...
Agricultural activities and risk of Alzheimer’s disease: the TRACTOR project, a nationwide retrospective cohort study
Agricultural activities and risk of Alzheimer’s disease: the TRACTOR project, a nationwide retrospective cohort study
Data regarding Alzheimer’s disease (AD) occurrence in farming populations is lacking. This study aimed to investigat...
The pitfalls of focusing on cardiovascular disease mortality to explain differences in life expectancy
The pitfalls of focusing on cardiovascular disease mortality to explain differences in life expectancy
Third, we think, non-health related factors (attitudes, culture, values) that constitute a population should receive more ...
Re: Statistical inference and effect measures in abstracts of randomized trials, 1975-2021
Re: Statistical inference and effect measures in abstracts of randomized trials, 1975-2021
Stang and Rothman recently presented an informative systematic review of statistical inference and effect measures in abst...
Authors’ Reply: Statistical inference and effect measures in abstracts of randomized trials, 1975-2021
Authors’ Reply: Statistical inference and effect measures in abstracts of randomized trials, 1975-2021
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Cohort profile: Beijing Healthy Aging Cohort Study (BHACS)
Cohort profile: Beijing Healthy Aging Cohort Study (BHACS)
The Beijing Healthy Aging Cohort Study (BHACS) was established to supplement the limited data of a large representative co...