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The association of myocardial infarction with cancer incidence
The association of myocardial infarction with cancer incidence
In this commentary, the authors discuss the potential mechanisms for the finding of an association between myocardial infa...
The influence of growth and sex hormones on risk of alzheimer’s disease: a mendelian randomization study
The influence of growth and sex hormones on risk of alzheimer’s disease: a mendelian randomization study
Alzheimer’s disease is more prevalent in women, possibly due to sex or growth hormones but existing evidence is inco...
Falsification of the instrumental variable conditions in Mendelian randomization studies in the UK Biobank
Falsification of the instrumental variable conditions in Mendelian randomization studies in the UK Biobank
Mendelian randomization (MR) is an increasingly popular approach to estimating causal effects. Although the assumptions un...
Synergistic effect of non-alcoholic fatty liver disease and history of gestational diabetes to increase risk of type 2 diabetes
Synergistic effect of non-alcoholic fatty liver disease and history of gestational diabetes to increase risk of type 2 diabetes
Whether non-alcoholic fatty liver disease (NAFLD) improves risk prediction for subsequent type 2 diabetes mellitus (T2DM) ...
Residential proximity to petrol stations and risk of childhood leukemia
Residential proximity to petrol stations and risk of childhood leukemia
Petrol stations emit benzene and other contaminants that have been associated with an increased risk of childhood leukemia...
Towards an integrated and life-course approach to the epidemiology of dementia
Towards an integrated and life-course approach to the epidemiology of dementia
Livingston G, Sommerlad A, Orgeta V, et al. Dementia prevention, intervention, and care. Lancet. 2017;390(10113):2673–734....
Lympho-hematopoietic malignancies risk after exposure to low dose ionizing radiation during cardiac catheterization in childhood
Lympho-hematopoietic malignancies risk after exposure to low dose ionizing radiation during cardiac catheterization in childhood
Pediatric patients with congenital heart disease (CHD) often undergo low dose ionizing radiation (LDIR) from cardiac cathe...
COVID-19 mortality and use of intensive care among ethnic minorities – a national register-based Danish population study
COVID-19 mortality and use of intensive care among ethnic minorities – a national register-based Danish population study
Migrants and ethnic minorities are disproportionately affected by the Coronavirus Disease 2019 (COVID-19) pandemic compare...
The role of environmental factors on sporadic Creutzfeldt-Jakob disease mortality: evidence from an age-period-cohort analysis
The role of environmental factors on sporadic Creutzfeldt-Jakob disease mortality: evidence from an age-period-cohort analysis
Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common form of prion diseases. The causes of sCJD are still unknown ...
The association of a combined healthy lifestyle with the risk of postmenopausal breast cancer subtypes in the Netherlands Cohort Study
The association of a combined healthy lifestyle with the risk of postmenopausal breast cancer subtypes in the Netherlands Cohort Study
The association between combined healthy lifestyle and postmenopausal breast cancer risk has been studied in various cohor...
Lipidomics and pancreatic cancer risk in two prospective studies
Lipidomics and pancreatic cancer risk in two prospective studies
Pancreatic ductal carcinoma (PDAC) is highly fatal with limited understanding of mechanisms underlying its carcinogenesis....
Cohort profile update: Tehran cardiometabolic genetic study
Cohort profile update: Tehran cardiometabolic genetic study
The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study that conducts periodic follow-ups...
Dietary patterns, brain morphology and cognitive performance in children: Results from a prospective population-based study
Dietary patterns, brain morphology and cognitive performance in children: Results from a prospective population-based study
Dietary patterns in childhood have been associated with child neurodevelopment and cognitive performance, while the underl...
Leveraging family history data to disentangle time-varying effects on disease risk using lifecourse mendelian randomization
Leveraging family history data to disentangle time-varying effects on disease risk using lifecourse mendelian randomization
Lifecourse Mendelian randomization is a causal inference technique which harnesses genetic variants with time-varying effe...
The intricate connection between diabetes mellitus and Parkinson’s disease
The intricate connection between diabetes mellitus and Parkinson’s disease
Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endoc...
Age-specific effects of weight-based body size on fracture risk in later life: a lifecourse Mendelian randomisation study
Age-specific effects of weight-based body size on fracture risk in later life: a lifecourse Mendelian randomisation study
Musculoskeletal conditions, including fractures, can have severe and long-lasting consequences. Higher body mass index in ...
Lessons from the Singapore cohorts showcase symposium—open call for collaborations
Lessons from the Singapore cohorts showcase symposium—open call for collaborations
Singapore Lipidomics Incubator (SLING), Life Sciences Institute, National University of Singapore, Singapore, SingaporeAnn...
Vitamin D status during pregnancy: a role in intergenerational reproductive health?
Vitamin D status during pregnancy: a role in intergenerational reproductive health?
Ginde AA, Sullivan AF, Mansbach JM, Camargo CA. Jr. Vitamin D insufficiency in pregnant and nonpregnant women of childbear...
The underwhelming German life expectancy
The underwhelming German life expectancy
This article contributes to the discussion on the determinants of diverging life expectancy in high-income countries, with...
Diabetes mellitus, prediabetes and the risk of Parkinson’s disease: a systematic review and meta-analysis of 15 cohort studies with 29.9 million participants and 86,345 cases
Diabetes mellitus, prediabetes and the risk of Parkinson’s disease: a systematic review and meta-analysis of 15 cohort studies with 29.9 million participants and 86,345 cases
A diagnosis of diabetes mellitus and prediabetes has been associated with increased risk of Parkinson’s disease (PD)...
Evaluating the harmonisation potential of diverse cohort datasets
Evaluating the harmonisation potential of diverse cohort datasets
Data discovery, the ability to find datasets relevant to an analysis, increases scientific opportunity, improves rigour an...
Plant-based dietary patterns and the risk of digestive system cancers in 3 large prospective cohort studies
Plant-based dietary patterns and the risk of digestive system cancers in 3 large prospective cohort studies
Little is known about the relation between plant-based dietary patterns and digestive system cancers. This study investiga...
Estimated preventable COVID-19-associated deaths due to non-vaccination in the United States
Estimated preventable COVID-19-associated deaths due to non-vaccination in the United States
While some studies have previously estimated lives saved by COVID-19 vaccination, we estimate how many deaths could have b...
What is the role of puberty in the development of islet autoimmunity and progression to type 1 diabetes?
What is the role of puberty in the development of islet autoimmunity and progression to type 1 diabetes?
In many populations, the peak period of incidence of type 1 diabetes (T1D) has been observed to be around 10–14&...
Inferring fetal growth restriction as rare, severe, and stable over time
Inferring fetal growth restriction as rare, severe, and stable over time
Reduced birthweight is a marker of pathologies that impair growth and also decrease survival. However, “fetal growth...
Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study
Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study
Despite increasing therapeutic options to treat rheumatoid arthritis (RA), many patients fail to reach treatment targets. ...
Target parameters and bias in non-causal change-score analyses with measurement errors
Target parameters and bias in non-causal change-score analyses with measurement errors
In studies where the outcome is a change-score, it is often debated whether or not the analysis should adjust for the base...
Healthy lifespan inequality: morbidity compression from a global perspective
Healthy lifespan inequality: morbidity compression from a global perspective
Current measures of population health lack indicators capturing the variability in age-at-morbidity onset, an important ma...
Profile of the multicenter cohort of the German Cancer Consortium’s Clinical Communication Platform
Profile of the multicenter cohort of the German Cancer Consortium’s Clinical Communication Platform
Treatment concepts in oncology are becoming increasingly personalized and diverse. Successively, changes in standards of c...
All-cause mortality among Danish nursing home residents before and during the COVID-19 pandemic: a nationwide cohort study
All-cause mortality among Danish nursing home residents before and during the COVID-19 pandemic: a nationwide cohort study
A substantial part of mortality during the COVID-19-pandemic occurred among nursing home residents which caused alarm in m...
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