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The need for evolutionary theory in cancer research
The need for evolutionary theory in cancer research
Sir Richard Peto is well known for proposing puzzling paradoxes in cancer biology—some more well-known than others. ...
On the evolution of concepts of causal and preventive interdependence in epidemiology in the late 20th century
On the evolution of concepts of causal and preventive interdependence in epidemiology in the late 20th century
The 1970s and 1980s saw the appearance of many papers on the topics of synergy, antagonism, and similar concepts of causal...
Thoughts on Miettinen’s “Causal and preventive interdependence: Elementary Principles.”
Thoughts on Miettinen’s “Causal and preventive interdependence: Elementary Principles.”
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Demystifying the black box: from ignorance to observation to mechanism in cancer research
Demystifying the black box: from ignorance to observation to mechanism in cancer research
Brennan P, Davey-Smith G. Identifying novel causes of cancers to enhance cancer prevention: new strategies are needed. J N...
Kidney function and risk of dementia: Observational study, meta-analysis, and two-sample mendelian randomization study
Kidney function and risk of dementia: Observational study, meta-analysis, and two-sample mendelian randomization study
Whether impaired kidney function is associated with increased risk of developing dementia is unclear. We investigated the ...
1976: the year epidemiology became Miettinenian
1976: the year epidemiology became Miettinenian
Morabia A. Has epidemiology become infatuated with methods? A historical perspective on the place of methods during the cl...
Zinc supplement use and risk of aggressive prostate cancer: a 30-year follow-up study
Zinc supplement use and risk of aggressive prostate cancer: a 30-year follow-up study
Zinc supplementation was hypothesized to have therapeutic potential against prostate cancer, but its influence on prostate...
A population-based cohort study of sex and risk of severe outcomes in covid-19
A population-based cohort study of sex and risk of severe outcomes in covid-19
There is a male sex disadvantage in morbidity and mortality due to COVID-19. Proposed explanations to this disparity inclu...
Framework and baseline examination of the German National Cohort (NAKO)
Framework and baseline examination of the German National Cohort (NAKO)
The German National Cohort (NAKO) is a multidisciplinary, population-based prospective cohort study that aims to investiga...
On Explaining Peto’s Paradox.
On Explaining Peto’s Paradox.
Peto R. The need for ignorance in cancer research. In Duncan, R. editor. the Encyclopedia of Medical Ignorance. 1984; pp. ...
Cohort profile: the Food Chain Plus (FoCus) cohort
Cohort profile: the Food Chain Plus (FoCus) cohort
The Food Chain Plus (FoCus) cohort was launched in 2011 for population-based research related to metabolic inflammation. T...
Inflammation, sauna bathing, and all-cause mortality in middle-aged and older Finnish men: a cohort study
Inflammation, sauna bathing, and all-cause mortality in middle-aged and older Finnish men: a cohort study
Inflammation and sauna bathing are each related to the risk of all-cause mortality. The interplay between inflammation, sa...
SARS-CoV-2 infections in professional orchestra and choir musicians—a prospective cohort study
SARS-CoV-2 infections in professional orchestra and choir musicians—a prospective cohort study
During the COVID-19 pandemic, rehearsal and concert activities of professional orchestras and choirs were severely restric...
Years of life lost during the Covid-19 pandemic in Sweden considering variation in life expectancy by level of geriatric care
Years of life lost during the Covid-19 pandemic in Sweden considering variation in life expectancy by level of geriatric care
The Covid-19 pandemic has not affected the population evenly. This must be acknowledged when it comes to understanding the...
The methodologies to assess the effectiveness of non-pharmaceutical interventions during COVID-19: a systematic review
The methodologies to assess the effectiveness of non-pharmaceutical interventions during COVID-19: a systematic review
Non-pharmaceutical interventions, such as school closures and stay-at-home orders, have been implemented around the world ...
Estimating conditional vaccine effectiveness
Estimating conditional vaccine effectiveness
Vaccine effectiveness for COVID-19 is typically estimated for different outcomes that often are hierarchical in severity (...
The long-term relation between physical activity and executive function in the Rotterdam Study
The long-term relation between physical activity and executive function in the Rotterdam Study
Research on the association between physical inactivity and cognitive decline and dementia is dominated by studies with sh...
Spatio-temporal clustering of amyotrophic lateral sclerosis in France: A population-based study
Spatio-temporal clustering of amyotrophic lateral sclerosis in France: A population-based study
To assess spatial aggregates of amyotrophic lateral sclerosis (ALS) incident cases, using a solid geo-epidemiological stat...
A longitudinal evaluation of alcohol intake throughout adulthood and colorectal cancer risk
A longitudinal evaluation of alcohol intake throughout adulthood and colorectal cancer risk
Alcohol intake is an established risk factor for colorectal cancer (CRC); however, there is limited knowledge on whether c...
Identifying potential causal effects of age at menopause: a Mendelian randomization phenome-wide association study
Identifying potential causal effects of age at menopause: a Mendelian randomization phenome-wide association study
Age at natural menopause (ANM) is associated with a range of health-related traits, including bone health, female reproduc...