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Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease: An international overview
Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease: An international overview
Abstract Introduction The current practice of quantifying cerebrospinal fluid (CSF) biomarkers as an aid in the diagnosis ...
Whole genome sequencing–based copy number variations reveal novel pathways and targets in Alzheimer's disease
Whole genome sequencing–based copy number variations reveal novel pathways and targets in Alzheimer's disease
Abstract Introduction A few copy number variations (CNVs) have been reported for Alzheimer's disease (AD). However, there ...
In situ spatial glycomic imaging of mouse and human Alzheimer's disease brains
In situ spatial glycomic imaging of mouse and human Alzheimer's disease brains
Abstract N-linked protein glycosylation in the brain is an understudied facet of glucose utilization that impacts a myriad...
Risk of Alzheimer's disease and related dementia by sex and race/ethnicity: The Multiethnic Cohort Study
Risk of Alzheimer's disease and related dementia by sex and race/ethnicity: The Multiethnic Cohort Study
Abstract Introduction Data are limited for comparison of sex- and race/ethnicity-specific risks of Alzheimer's disease and...
A longitudinal investigation of Aβ, anxiety, depression, and mild cognitive impairment
A longitudinal investigation of Aβ, anxiety, depression, and mild cognitive impairment
Abstract Introduction We investigated the longitudinal relationship between cortical amyloid deposition, anxiety, and depr...
The protective gene dose effect of the APOE ε2 allele on gray matter volume in cognitively unimpaired individuals
The protective gene dose effect of the APOE ε2 allele on gray matter volume in cognitively unimpaired individuals
Abstract Introduction Harboring two copies of the apolipoprotein E (APOE) ε2 allele strongly protects against Alzhei...
Characteristics of subjective cognitive decline associated with amyloid positivity
Characteristics of subjective cognitive decline associated with amyloid positivity
Abstract Introduction The evidence for characteristics of persons with subjective cognitive decline (SCD) associated with ...
How good are medical and death records for identifying dementia?
How good are medical and death records for identifying dementia?
Abstract Introduction Retrospective studies using administrative data may be an efficient way to assess risk factors for d...
Effect of cognitive impairment on risk of death in Hispanic/Latino adults over the age of 50 residing in the United States with and without diabetes: Data from the Health and Retirement Study 1995–2014
Effect of cognitive impairment on risk of death in Hispanic/Latino adults over the age of 50 residing in the United States with and without diabetes: Data from the Health and Retirement Study 1995–2014
Abstract Objective To understand the relationship between mortality and cognitive function among older US Hispanic adults ...
Differential expression of tau species and the association with cognitive decline and synaptic loss in Alzheimer's disease
Differential expression of tau species and the association with cognitive decline and synaptic loss in Alzheimer's disease
Abstract Pathological tau proteins in patients with Alzheimer's disease (AD) mainly accumulate in the form of neurofibrill...
Adults with Down syndrome in randomized clinical trials targeting prevention of Alzheimer's disease
Adults with Down syndrome in randomized clinical trials targeting prevention of Alzheimer's disease
Abstract Introduction Adults with Down syndrome, the largest population genetically predisposed to high risk for Alzheimer...
Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance
Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance
Abstract Identifying genes underlying memory function will help characterize cognitively resilient and high-risk declining...
Impact of COVID‐19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research
Impact of COVID‐19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research
Abstract COVID-19 causes lasting neurological symptoms in some survivors. Like other infections, COVID-19 may increase ris...
Normal cerebrospinal fluid concentrations of PDGFRβ in patients with cerebral amyloid angiopathy and Alzheimer's disease
Normal cerebrospinal fluid concentrations of PDGFRβ in patients with cerebral amyloid angiopathy and Alzheimer's disease
Abstract Background: Cerebrospinal fluid (CSF) platelet-derived growth factor receptor-β (PDGFRβ) has been pro...
Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia
Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia
Abstract The presymptomatic stages of frontotemporal dementia (FTD) are still poorly defined and encompass a long accrual ...
Association of resting heart rate with cognitive decline and dementia in older adults: A population‐based cohort study
Association of resting heart rate with cognitive decline and dementia in older adults: A population‐based cohort study
Abstract Introduction: Resting heart rate (RHR) predicts future risk for cardiovascular disease (CVD). However, longitudin...
Body mass index in early adulthood and dementia in late life: Findings from a pooled cohort
Body mass index in early adulthood and dementia in late life: Findings from a pooled cohort
Abstract Introduction To examine the independent association of body mass index (BMI) in early adulthood with dementia inc...
Dementia is an age‐independent risk factor for severity and death in COVID‐19 inpatients
Dementia is an age‐independent risk factor for severity and death in COVID‐19 inpatients
Abstract Introduction Dementia has been associated with COVID-19 prevalence, but whether this reflects higher infection, o...
Health utility in preclinical and prodromal Alzheimer's disease for establishing the value of new disease‐modifying treatments—EQ‐5D data from the Swedish BioFINDER study
Health utility in preclinical and prodromal Alzheimer's disease for establishing the value of new disease‐modifying treatments—EQ‐5D data from the Swedish BioFINDER study
Abstract Quality of life and health utility are important outcomes for patients with Alzheimer's disease (AD) and central ...
Alzheimer's disease biomarkers in Black and non‐Hispanic White cohorts: A contextualized review of the evidence
Alzheimer's disease biomarkers in Black and non‐Hispanic White cohorts: A contextualized review of the evidence
Abstract Black Americans are disproportionately affected by dementia. To expand our understanding of mechanisms of this di...
What can 7T sodium MRI tell us about cellular energy depletion and neurotransmission in Alzheimer's disease?
What can 7T sodium MRI tell us about cellular energy depletion and neurotransmission in Alzheimer's disease?
Abstract The pathophysiological processes underlying the development and progression of Alzheimer's disease (AD) on the ne...
Plasma p‐tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau
Plasma p‐tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau
Abstract Introduction We examined the ability of plasma hyperphosphorylated tau (p-tau)181 to detect cognitive impairment ...
AAIC 2021: The promise of Alzheimer's research
AAIC 2021: The promise of Alzheimer's research
Please check your email for instructions on resetting your password. If you do not r...
Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation
Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation
Abstract Introduction Although dementia prevalence differs by race, it remains unclear whether cognition and neuropsychiat...
Different rates of cognitive decline in autosomal dominant and late‐onset Alzheimer disease
Different rates of cognitive decline in autosomal dominant and late‐onset Alzheimer disease
Abstract As prevention trials advance with autosomal dominant Alzheimer disease (ADAD) participants, understanding the sim...
Social cognition assessment for mild neurocognitive disorders
Social cognition assessment for mild neurocognitive disorders
Early View LETTER Jan Van den Stock, Corresponding Author KU Leuven, L...
Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease
Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease
Abstract Introduction Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with repetitive h...
The contribution of behavioral features to caregiver burden in FTLD spectrum disorders
The contribution of behavioral features to caregiver burden in FTLD spectrum disorders
Abstract Introduction Caregivers of patients with frontotemporal lobar degeneration (FTLD) spectrum disorders experience t...
Characterization of pre‐analytical sample handling effects on a panel of Alzheimer's disease–related blood‐based biomarkers: Results from the Standardization of Alzheimer's Blood Biomarkers (SABB) working group
Characterization of pre‐analytical sample handling effects on a panel of Alzheimer's disease–related blood‐based biomarkers: Results from the Standardization of Alzheimer's Blood Biomarkers (SABB) working group
Abstract Introduction Pre-analytical sample handling might affect the results of Alzheimer's disease blood-based biomarker...
Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal‐derived extracellular vesicles
Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal‐derived extracellular vesicles
Abstract Introduction Intellectual disability, accelerated aging, and early-onset Alzheimer-like neurodegeneration are key...
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