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Expression of LC3A, LC3B and p62/SQSTM1 autophagy proteins in hepatocellular carcinoma (HCC) tissues and the predicted microRNAs involved in the autophagy-related pathway
Expression of LC3A, LC3B and p62/SQSTM1 autophagy proteins in hepatocellular carcinoma (HCC) tissues and the predicted microRNAs involved in the autophagy-related pathway
Autophagy plays multifaceted roles in regulating hepatocellular carcinoma (HCC) and the mechanisms involved are under-expl...
Human neural stem cell secretome relieves endoplasmic reticulum stress-induced apoptosis and improves neuronal functions after traumatic brain injury in a rat model
Human neural stem cell secretome relieves endoplasmic reticulum stress-induced apoptosis and improves neuronal functions after traumatic brain injury in a rat model
Neural stem cell secretome (NSC-S) plays an important role in neuroprotection and recovery. Studies have shown that endopl...
Subcellular expression of MTA1, HIF1A and p53 in primary tumor predicts aggressive triple negative breast cancers: a meta-analysis based study
Subcellular expression of MTA1, HIF1A and p53 in primary tumor predicts aggressive triple negative breast cancers: a meta-analysis based study
The prevalence of TNBC in India is higher compared to western countries. There is a multitude of biomarkers associated wit...
Germ cell-specific gene 2 accelerates cell cycle in epithelial ovarian cancer by inhibiting GSK3α-p27 cascade
Germ cell-specific gene 2 accelerates cell cycle in epithelial ovarian cancer by inhibiting GSK3α-p27 cascade
Epithelial ovarian cancer (EOC) is one of the most common malignant gynecological tumors with rapid growth potential and p...
Effect of Oxygen–Glucose Deprivation of Microglia-Derived Exosomes on Hippocampal Neurons: A Study on miR-124 and Inflammatory Cytokines
Effect of Oxygen–Glucose Deprivation of Microglia-Derived Exosomes on Hippocampal Neurons: A Study on miR-124 and Inflammatory Cytokines
Stroke is a cerebrovascular disease that threatens human health. Developing safe and effective drugs and finding therapeut...
Chronic unpredictable mild stress increases serum aldosterone without affecting corticosterone levels and induces hepatic steatosis and renal injury in young adult male rats
Chronic unpredictable mild stress increases serum aldosterone without affecting corticosterone levels and induces hepatic steatosis and renal injury in young adult male rats
Stress is often associated with anxiety and depressive symptoms in adolescents. Stress is associated with components of me...
Differential tempol effects in prostatic cancer: angiogenesis and short- and long-term treatments
Differential tempol effects in prostatic cancer: angiogenesis and short- and long-term treatments
Prostate cancer (PCa) is the second cause of cancer death among men worldwide. Several processes are involved in the devel...
New insights into the treatment of polycystic ovary syndrome: HKDC1 promotes the growth of ovarian granulocyte cells by regulating mitochondrial function and glycolysis
New insights into the treatment of polycystic ovary syndrome: HKDC1 promotes the growth of ovarian granulocyte cells by regulating mitochondrial function and glycolysis
Polycystic ovary syndrome (PCOS) is an endocrine disease, and its pathogenesis and treatment are still unclear. Hexokinase...
Quercetin promotes ATG5-mediating autophagy-dependent ferroptosis in gastric cancer
Quercetin promotes ATG5-mediating autophagy-dependent ferroptosis in gastric cancer
Quercetin has been documented to possess a multitude of pharmacological effects, encompassing antioxidant, antiviral, anti...
Regulatory role of N-myc downregulated genes in amelogenesis in rats
Regulatory role of N-myc downregulated genes in amelogenesis in rats
Cytodifferentiation of odontogenic cells, a late stage event in odontogenesis is based on gene regulation. However, studie...
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice
The activation of toll-like receptor 3 (TLR3) has been reported to attenuate astrocytes injury in central nervous system, ...
BLVRA exerts its biological effects to induce malignant properties of hepatocellular carcinoma cells via Wnt/β-catenin pathway
BLVRA exerts its biological effects to induce malignant properties of hepatocellular carcinoma cells via Wnt/β-catenin pathway
The function of Biliverdin Reductase A (BLVRA) in hepatocellular carcinoma (HCC) cells proliferation, invasion and migrati...
LRRC1 knockdown downregulates MACF1 to inhibit the malignant progression of acute myeloid leukemia by inactivating β-catenin/c-Myc signaling
LRRC1 knockdown downregulates MACF1 to inhibit the malignant progression of acute myeloid leukemia by inactivating β-catenin/c-Myc signaling
Acute myeloid leukemia (AML) is a hematologic disease associated with genetic abnormalities. This study aimed to explore t...
The lncRNA lnc-TSI antagonizes sorafenib resistance in hepatocellular carcinoma via downregulating miR-4726-5p expression and upregulating KCNMA1 expression
The lncRNA lnc-TSI antagonizes sorafenib resistance in hepatocellular carcinoma via downregulating miR-4726-5p expression and upregulating KCNMA1 expression
Acquired drug resistance is a main reason for limiting the application of sorafenib in HCC treatment. This study aimed to ...
Knockout of KDM3A in MDA-MB-231 breast cancer cells inhibits tumor malignancy and promotes apoptosis
Knockout of KDM3A in MDA-MB-231 breast cancer cells inhibits tumor malignancy and promotes apoptosis
The histone lysine demethylase 3 A (KDM3A) is vital for the regulation of cancer physiology and pathophysiology. ...
Sestrin2 ameliorates diabetic retinopathy by regulating autophagy and ferroptosis
Sestrin2 ameliorates diabetic retinopathy by regulating autophagy and ferroptosis
Diabetic retinopathy (DR) is a serious microvascular complication of diabetes. The aim of this study was to explore the ef...
VNS improves VSMC metabolism and arteriogenesis in infarcted hearts through m/n-AChR-Akt-SDF-1α in adult male rats
VNS improves VSMC metabolism and arteriogenesis in infarcted hearts through m/n-AChR-Akt-SDF-1α in adult male rats
Vagal nerve stimulation (VNS) provides a novel therapeutic strategy for injured hearts by activating cholinergic anti-infl...
Oncogenic lncRNA FAM215A promotes the malignant cell phenotypes of acute myeloid leukemia (AML) cell lines
Oncogenic lncRNA FAM215A promotes the malignant cell phenotypes of acute myeloid leukemia (AML) cell lines
Acute myeloid leukemia (AML) is a form of blood cancer that arise as a result of clonal proliferation of malignant myeloid...
Orientin alleviates ox-LDL-induced oxidative stress, inflammation and apoptosis in human vascular endothelial cells by regulating Sestrin 1 (SESN1)-mediated autophagy
Orientin alleviates ox-LDL-induced oxidative stress, inflammation and apoptosis in human vascular endothelial cells by regulating Sestrin 1 (SESN1)-mediated autophagy
Endothelial cells are a crucial component of the vessel-tissue wall and exert an important role in atherosclerosis (AS). T...
TOB1 and TOB2 mark distinct RNA processing granules in differentiating lens fiber cells
TOB1 and TOB2 mark distinct RNA processing granules in differentiating lens fiber cells
Differentiation of lens fiber cells involves a complex interplay of signals from growth factors together with tightly regu...
Silenced-C5ar1 improved multiple organ injury in sepsis rats via inhibiting neutrophil extracellular trap
Silenced-C5ar1 improved multiple organ injury in sepsis rats via inhibiting neutrophil extracellular trap
Sepsis has a systemic inflammatory response syndrome caused by infection. While neutrophils play contradictory roles in di...
Overview of the compromised mucosal integrity in celiac disease
Overview of the compromised mucosal integrity in celiac disease
Intestinal epithelium is a dynamic cellular layer that lines the small-bowel and makes a relatively impenetrable barrier t...
LOC102549726/miR-760-3p network is involved in the progression of ISO-induced pathological cardiomyocyte hypertrophy via endoplasmic reticulum stress
LOC102549726/miR-760-3p network is involved in the progression of ISO-induced pathological cardiomyocyte hypertrophy via endoplasmic reticulum stress
Pathological cardiac hypertrophy (CH) is featured by myocyte enlargement and cardiac malfunction. Multiple signaling pathw...
Investigation of miR-26b and miR-27b expressions and the effect of quercetin on fibrosis in experimental pulmonary fibrosis
Investigation of miR-26b and miR-27b expressions and the effect of quercetin on fibrosis in experimental pulmonary fibrosis
In this study, investigation of the effects of Quercetin on Bleomycin-induced pulmonary fibrosis and fibrosis-associated m...
The circSNX14 functions as a tumor suppressor via the miR-562/ LATS2 pathway in hepatocellular carcinoma cells
The circSNX14 functions as a tumor suppressor via the miR-562/ LATS2 pathway in hepatocellular carcinoma cells
Circular RNAs (circRNAs) play critical roles in the initiation and progression of various cancers. However, the potential ...
Mitochondria as a target for exercise-mitigated type 2 diabetes
Mitochondria as a target for exercise-mitigated type 2 diabetes
Type 2 diabetes mellitus (T2DM) is one of most common metabolic diseases and continues to be a leading cause of death worl...
Effects of abnormal expression of CD73 on malignant phenotype of nasopharyngeal carcinoma
Effects of abnormal expression of CD73 on malignant phenotype of nasopharyngeal carcinoma
Cluster of differentiation (CD) 73, encoded by the NT5E gene, plays important enzymatic and non-enzymatic roles in cells. ...
Osteopontin: an essential regulatory protein in idiopathic pulmonary fibrosis
Osteopontin: an essential regulatory protein in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic lung disease characterized by abnormal proliferation and act...
Intra-articular delivery of geraniol encapsulated by pH/redox-responsive nanogel ameliorates osteoarthritis by regulating oxidative stress and inflammation
Intra-articular delivery of geraniol encapsulated by pH/redox-responsive nanogel ameliorates osteoarthritis by regulating oxidative stress and inflammation
Osteoarthritis (OA) remains a challenging condition due to limited drug bioavailability within the avascular and dense car...
The ratio of alpha-calcitonin gene-related peptide to substance P is associated with the transition of bone metabolic states during aging and healing
The ratio of alpha-calcitonin gene-related peptide to substance P is associated with the transition of bone metabolic states during aging and healing
Alpha-calcitonin gene-related peptide (αCGRP) and substance P (SP) are functionally correlated sensory neuropeptides ...
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