SCI时时刷

search
+
Angelica sinensis polysaccharides promote extramedullary stress erythropoiesis via ameliorating splenic glycolysis and EPO/STAT5 signaling-regulated macrophages
Angelica sinensis polysaccharides promote extramedullary stress erythropoiesis via ameliorating splenic glycolysis and EPO/STAT5 signaling-regulated macrophages
Conventional treatments exhibit various side effects on chronic stress anemia. Extramedullary stress erythropoiesis is a c...
TUG1 exacerbates cerebral ischemia-reperfusion injury through miR-340-5p-mediated PTEN
TUG1 exacerbates cerebral ischemia-reperfusion injury through miR-340-5p-mediated PTEN
Long non-coding RNAs (LncRNAs) play a substantial role in the process of cerebral ischemia-reperfusion injury (CIRI). The ...
Pre-mating exposure with hesperidin protects N-ethyl-N-nitrosourea-induced neurotoxicity and congenital abnormalities in next generation of mice as a model of glioma
Pre-mating exposure with hesperidin protects N-ethyl-N-nitrosourea-induced neurotoxicity and congenital abnormalities in next generation of mice as a model of glioma
Chemical carcinogen-induced oxidative stress has a key role in cell signaling linked to the development of cancer. Oxidati...
Wood calamint ameliorates ethanol-induced stomach injury in rats by augmentation of hsp/bax and inflammatory mechanisms
Wood calamint ameliorates ethanol-induced stomach injury in rats by augmentation of hsp/bax and inflammatory mechanisms
Clinopodium menthifolium (wood calamint) is a folkloric medicinal plant ingested as a treatment for many human disorders i...
Protective effect of rubber seed oil on human endothelial cells
Protective effect of rubber seed oil on human endothelial cells
This study was conducted to characterize the antioxidant and anti-inflammatory properties of Rubber Seed Oil (RSO) against...
Interleukin-10 deficiency induces thoracic perivascular adipose tissue whitening and vascular remodeling
Interleukin-10 deficiency induces thoracic perivascular adipose tissue whitening and vascular remodeling
Absence of endogenous IL-10 reduces total thoracic PVAT. Brown adipose PVAT whitening is observed in thoracic aortas from ...
Anshen Shumai Decoction inhibits post-infarction inflammation and myocardial remodeling through suppression of the p38 MAPK/c-FOS/EGR1 pathway
Anshen Shumai Decoction inhibits post-infarction inflammation and myocardial remodeling through suppression of the p38 MAPK/c-FOS/EGR1 pathway
Anshen Shumai Decoction (ASSMD) is traditionally employed to manage coronary artery disease arrhythmias. Its protective ef...
Ucf-101 alleviates Ischaemia/Reperfusion induced retinal inflammation and injury via suppressing oxidative damage
Ucf-101 alleviates Ischaemia/Reperfusion induced retinal inflammation and injury via suppressing oxidative damage
The Omi/HtrA2 inhibitor 5-[5-(2-nitrophenyl) furfuryliodine]-1,3-diphenyl-2-thiobarbituric acid (Ucf-101) has shown neurop...
SPP-5 affects larval arrest via insulin signaling pathway in Caenorhabditis elegans
SPP-5 affects larval arrest via insulin signaling pathway in Caenorhabditis elegans
Diapause is an endocrine-mediated metabolic and growth arrest state in response to unfavorable external environments. The ...
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells
Background: Sorting nexin 14 (SNX14) is a member of the sorting junction protein family. Its specific roles in cancer deve...
STAT1 aggravates kidney injury by NOD-like receptor (NLRP3) signaling in MRL-lpr mice
STAT1 aggravates kidney injury by NOD-like receptor (NLRP3) signaling in MRL-lpr mice
Systemic lupus erythematosus (SLE) is a persistent autoimmune disorder that can culminate in lupus nephritis (LN), an intr...
Zinc-alkaline phosphatase at sites of aortic calcification
Zinc-alkaline phosphatase at sites of aortic calcification
Zinc (Zn) is a normal trace element in mineralizing tissues, but it is unclear whether it is primarily bound to the minera...
Altered DNA methylation and Dnmt expression in obese uterus may cause implantation failure
Altered DNA methylation and Dnmt expression in obese uterus may cause implantation failure
Obesity is defined by increased adipose tissue volume and has become a major risk factor for reproduction. Recent studies ...
KLF9 regulates osteogenic differentiation of mesenchymal stem cells
KLF9 regulates osteogenic differentiation of mesenchymal stem cells
Osteoporosis is a progressive skeletal disease which is characterized by reduced bone mass and degradation of bone microst...
Aβ1−42 stimulates an increase in autophagic activity through tunicamycin-induced endoplasmic reticulum stress in HTR-8/SVneo cells and late-onset pre-eclampsia
Aβ1−42 stimulates an increase in autophagic activity through tunicamycin-induced endoplasmic reticulum stress in HTR-8/SVneo cells and late-onset pre-eclampsia
Environmental changes can trigger endoplasmic reticulum (ER) stress and misfolded protein accumulation, potentially leadin...
Exercise protects the hypothalamus morphology from the deleterious effects of high sucrose diet consumption
Exercise protects the hypothalamus morphology from the deleterious effects of high sucrose diet consumption
A growing body of evidence suggests that elevated sucrose intake may contribute to the development of neurological disorde...
Bioinformatics proved the existence of potential hub genes activating autophagy to participate in cartilage degeneration in osteonecrosis of the femoral head
Bioinformatics proved the existence of potential hub genes activating autophagy to participate in cartilage degeneration in osteonecrosis of the femoral head
The obvious degeneration of articular cartilage occurs in the late stage of osteonecrosis of the femoral head (ONFH), whic...
Induction of Peroxiredoxin 1 by Hypoxia Promotes Cellular Autophagy and Cell Proliferation in Oral Leukoplakia via HIF-1α/BNIP3 Pathway
Induction of Peroxiredoxin 1 by Hypoxia Promotes Cellular Autophagy and Cell Proliferation in Oral Leukoplakia via HIF-1α/BNIP3 Pathway
Hypoxia is a key trigger in the transformation of oral leukoplakia into oral cancer. However, it is still too early to det...
Design and application of Cd2+ polypeptide fluorescent probes based on Aggregation Induced Emission (AIE)
Design and application of Cd2+ polypeptide fluorescent probes based on Aggregation Induced Emission (AIE)
Cadmium is a toxic heavy metal, which is both an environmental pollutant, and a threat to human health. A fluorescent prob...
Content and tissue expression of Collagen I, Collagen IV, and Laminin in the Extracellular Matrix in Prostate Adenocarcinoma
Content and tissue expression of Collagen I, Collagen IV, and Laminin in the Extracellular Matrix in Prostate Adenocarcinoma
Prostate cancer is one of the most common neoplasm in the male population. It is not known why some tumors become more agg...
Prenatal aripiprazole induces alterations of rat placenta: a histological, immunohistochemical and ultrastructural study
Prenatal aripiprazole induces alterations of rat placenta: a histological, immunohistochemical and ultrastructural study
Antipsychotic drugs (APDs) are used to treat many psychiatric illnesses as schizophrenia. Typical antipsychotic drugs (TAP...
An overview on liposarcoma subtypes: Genetic alterations and recent advances in therapeutic strategies
An overview on liposarcoma subtypes: Genetic alterations and recent advances in therapeutic strategies
Liposarcoma (LPS) is a rare malignancy of adipocytic differentiation. According to World Health Organization classificatio...
miR-199a-5p modulates choroidal neovascularization by regulating Wnt7b/Wnt/β-catenin signaling pathway
miR-199a-5p modulates choroidal neovascularization by regulating Wnt7b/Wnt/β-catenin signaling pathway
Choroidal neovascularization (CNV) can be seen in many fundus diseases, and lead to fundus exudation, bleeding, or vision ...
Evaluation of histological and ultrastructural changes provoked by prenatal tramadol on postnatal cortical cerebellar neuronal development in rats: possible implication of Ki67, GFAP and MicroRNA-7/P53 signalling trajectories
Evaluation of histological and ultrastructural changes provoked by prenatal tramadol on postnatal cortical cerebellar neuronal development in rats: possible implication of Ki67, GFAP and MicroRNA-7/P53 signalling trajectories
Tramadol is a novel centrally acting analgesic. Despite, its implementation during pregnancy may impair neuronal survival ...
Expression of LC3A, LC3B and p62/SQSTM1 autophagy proteins in hepatocellular carcinoma (HCC) tissues and the predicted microRNAs involved in the autophagy-related pathway
Expression of LC3A, LC3B and p62/SQSTM1 autophagy proteins in hepatocellular carcinoma (HCC) tissues and the predicted microRNAs involved in the autophagy-related pathway
Autophagy plays multifaceted roles in regulating hepatocellular carcinoma (HCC) and the mechanisms involved are under-expl...
Human neural stem cell secretome relieves endoplasmic reticulum stress-induced apoptosis and improves neuronal functions after traumatic brain injury in a rat model
Human neural stem cell secretome relieves endoplasmic reticulum stress-induced apoptosis and improves neuronal functions after traumatic brain injury in a rat model
Neural stem cell secretome (NSC-S) plays an important role in neuroprotection and recovery. Studies have shown that endopl...
Subcellular expression of MTA1, HIF1A and p53 in primary tumor predicts aggressive triple negative breast cancers: a meta-analysis based study
Subcellular expression of MTA1, HIF1A and p53 in primary tumor predicts aggressive triple negative breast cancers: a meta-analysis based study
The prevalence of TNBC in India is higher compared to western countries. There is a multitude of biomarkers associated wit...
Germ cell-specific gene 2 accelerates cell cycle in epithelial ovarian cancer by inhibiting GSK3α-p27 cascade
Germ cell-specific gene 2 accelerates cell cycle in epithelial ovarian cancer by inhibiting GSK3α-p27 cascade
Epithelial ovarian cancer (EOC) is one of the most common malignant gynecological tumors with rapid growth potential and p...
Effect of Oxygen–Glucose Deprivation of Microglia-Derived Exosomes on Hippocampal Neurons: A Study on miR-124 and Inflammatory Cytokines
Effect of Oxygen–Glucose Deprivation of Microglia-Derived Exosomes on Hippocampal Neurons: A Study on miR-124 and Inflammatory Cytokines
Stroke is a cerebrovascular disease that threatens human health. Developing safe and effective drugs and finding therapeut...
Chronic unpredictable mild stress increases serum aldosterone without affecting corticosterone levels and induces hepatic steatosis and renal injury in young adult male rats
Chronic unpredictable mild stress increases serum aldosterone without affecting corticosterone levels and induces hepatic steatosis and renal injury in young adult male rats
Stress is often associated with anxiety and depressive symptoms in adolescents. Stress is associated with components of me...
阅读更多
format_indent_increase