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Evaluation of a Novel Skin Emollient Cream on Skin Lipidome and Lipid Organization
Evaluation of a Novel Skin Emollient Cream on Skin Lipidome and Lipid Organization
<b><i>Introduction:</i></b> The <i>stratum corneum</i> (SC) matrix is composed of free...
The Effects of Mucopolysaccharide Polysulfate on Steroid-Induced Tight Junction Barrier Dysfunction in Human Epidermal Keratinocytes and a 3D Skin Model
The Effects of Mucopolysaccharide Polysulfate on Steroid-Induced Tight Junction Barrier Dysfunction in Human Epidermal Keratinocytes and a 3D Skin Model
Introduction: The long-term use of topical corticosteroids (TCS) is associated with side effects such as skin atrophy and ...
The epidermal environment’s influence on the dermal environment in response to external stress
The epidermal environment’s influence on the dermal environment in response to external stress
Introduction: The outermost layer of the skin, the epidermis, is directly exposed to external stress (e.g., irradiation, a...
Skin physiology, mucosal functions and symptoms are modulated by grass pollen and ozone double exposure in allergic patients
Skin physiology, mucosal functions and symptoms are modulated by grass pollen and ozone double exposure in allergic patients
Introduction: Along with climate changes, we see an increase in allergic symptoms and the number of pollen-allergic patien...
Alterations in Epidermal Biophysical Properties in Autistic Children
Alterations in Epidermal Biophysical Properties in Autistic Children
Autism is a neurodevelopmental disorder. Individuals with autism can exhibit multiple neurological symptoms such as defici...
Development of an In Vitro Functional Assay to Evaluate the Occlusive Properties of Moisturizers on Dry Skin
Development of an In Vitro Functional Assay to Evaluate the Occlusive Properties of Moisturizers on Dry Skin
Introduction: Dry skin is a hallmark of impaired skin barrier function. Moisturizers are a mainstay of treatment to help t...
Skin care in neonates and infants - a scoping review
Skin care in neonates and infants - a scoping review
Background Skin care is a basic, daily activity performed by formal and informal caregivers from birth until end of life. ...
Evaluation of a novel skin emollient cream on skin lipidome and lipids organization
Evaluation of a novel skin emollient cream on skin lipidome and lipids organization
Introduction: The stratum corneum (SC) matrix is composed of free fatty acids, cholesterol and ceramides (CERs), which pla...
MAPK/AP-1 signaling pathway is involved in the protection mechanism of bone marrow mesenchymal stem cells-derived exosomes against Ultraviolet-induced photoaging in human dermal fibroblasts
MAPK/AP-1 signaling pathway is involved in the protection mechanism of bone marrow mesenchymal stem cells-derived exosomes against Ultraviolet-induced photoaging in human dermal fibroblasts
Introduction: The role of bone marrow mesenchymal stem cells derived exosomes (BMSCs-exo) in skin photoaging was explored ...
Permethrin steal effect by unmasked corneocytic keratin in topical therapy of scabies
Permethrin steal effect by unmasked corneocytic keratin in topical therapy of scabies
Introduction: The use of epicutaneously applied permethrin in the treatment of common scabies is considered to be the firs...
Application of topical Sandalore® increases epidermal dermcidin synthesis in organ-cultured human skin ex vivo.
Application of topical Sandalore® increases epidermal dermcidin synthesis in organ-cultured human skin ex vivo.
Introduction: Several olfactory receptors (ORs) are expressed in human skin, where they regulate skin pigmentation, barrie...
Dermal and Transdermal Macromolecule Delivery Using Enhancer Molecules and Colloidal Carrier Systems – Part 2: Percutaneous Administration of Heparin
Dermal and Transdermal Macromolecule Delivery Using Enhancer Molecules and Colloidal Carrier Systems – Part 2: Percutaneous Administration of Heparin
<b><i>Introduction:</i></b> Heparin is a commonly used anti-coagulant administered either by intra...
Microinjury-Induced Tumor Necrosis Factor-α Surge Stimulates Hair Regeneration in Mice
Microinjury-Induced Tumor Necrosis Factor-α Surge Stimulates Hair Regeneration in Mice
<b><i>Introduction:</i></b> Tumor necrosis factor (TNF)-α released after follicular injury such as...
Histamine skin prick tests: from established diagnostic technique to advanced experimental biomarker
Histamine skin prick tests: from established diagnostic technique to advanced experimental biomarker
Introduction Skin prick tests have a long history as diagnostic and pharmacodynamic biomarker. Besides visual assessments ...
A Phase I Study to Evaluate the Safety and Pharmacokinetics of SHR0302 Base Ointment in Healthy Adult Volunteers
A Phase I Study to Evaluate the Safety and Pharmacokinetics of SHR0302 Base Ointment in Healthy Adult Volunteers
Introduction: SHR0302 is a highly selective JAK1 inhibitor. This study aims to investigate the safety, tolerability, and p...
Development of an efficient extraction methodology to analyse potential inflammatory biomarkers from sebum
Development of an efficient extraction methodology to analyse potential inflammatory biomarkers from sebum
Introduction: Proteins, such as cytokines and chemokines, are present in varying concentrations in a range of biofluids, ...
Contents Vol. 35, 2022
Contents Vol. 35, 2022
Skin Pharmaco...
Trichoscopic diagnosis of structural hair defects in a clinical setting: A Cross-sectional analytical study
Trichoscopic diagnosis of structural hair defects in a clinical setting: A Cross-sectional analytical study
Background: Trichoscopy is a simple, non-invasive procedure practiced in the diagnosis of a multitude of scalp and hair di...
Dermal and transdermal macromolecule delivery using enhancer molecules and colloidal carrier systems. Part II: Percutaneous administration of heparin
Dermal and transdermal macromolecule delivery using enhancer molecules and colloidal carrier systems. Part II: Percutaneous administration of heparin
Introduction: Heparin is a commonly used anticoagulant administered either by intravenous or subcutaneous injection for a ...
Free fatty acids induce lipid accumulation, autophagy and apoptosis in human sebocytes
Free fatty acids induce lipid accumulation, autophagy and apoptosis in human sebocytes
Background: A disruption of sebocyte differentiation and lipogenesis has fatal consequences and can cause a wide spectrum ...
Topically confined enhancement of cutaneous microcirculation by cold plasma
Topically confined enhancement of cutaneous microcirculation by cold plasma
Introduction: We aim to explore potentials and modalities of cold atmospheric pressure plasma (CAP) for the subsequent dev...
Challenges in noninvasive skin biomarker measurements in daily practice: a longitudinal study on skin surface protein detection by the Transdermal Analysis Patch in pediatric psoriasis
Challenges in noninvasive skin biomarker measurements in daily practice: a longitudinal study on skin surface protein detection by the Transdermal Analysis Patch in pediatric psoriasis
Introduction: Skin surface proteins are potential biomarkers in psoriasis and can be measured noninvasively with the Trans...
Direct and Indirect Effects of Blue Light Exposure on Skin: A Review of Published Literature
Direct and Indirect Effects of Blue Light Exposure on Skin: A Review of Published Literature
The growing use of electronic devices and other artificial light sources in recent decades has changed the pattern of expo...
Sinomenine suppressed keratinocyte proliferation and imiquimod-induced psoriasis-like dermatitis by regulating lncRNA XIST
Sinomenine suppressed keratinocyte proliferation and imiquimod-induced psoriasis-like dermatitis by regulating lncRNA XIST
Background: Psoriasis is a chronic inflammatory skin disease. Sinomenine (SIN) has anti-inflammatory and antioxidant effec...
Acidic skin care promotes cutaneous microbiome recovery and skin physiology in an acute stratum corneum stress model
Acidic skin care promotes cutaneous microbiome recovery and skin physiology in an acute stratum corneum stress model
Introduction: Skin microbiome and skin physiology are important indicators of the epidermal homeostasis status. Stress mod...
Expression of Signal Transducer and Activator of Transcription-3 in Androgenetic Alopecia: A case control study
Expression of Signal Transducer and Activator of Transcription-3 in Androgenetic Alopecia: A case control study
Background: Signal transducer and activator of transcription (STAT)-3 belongs to a group of latent transcription factors p...
Evaluation of an efficient and skin-adherent semisolid sunscreen nanoformulation
Evaluation of an efficient and skin-adherent semisolid sunscreen nanoformulation
Introduction: Sunscreens are substances applied on the skin surface to protect the skin from the harmful effects of UV lig...
Comparison of lipid foam cream and basic cream on epidermal reconstruction in mild atopic eczema
Comparison of lipid foam cream and basic cream on epidermal reconstruction in mild atopic eczema
Introduction: Basic therapy is of central importance in the treatment of atopic eczema. Using electron microscopic images,...
The emerging therapeutic targets for scar management: genetic and epigenetic landscapes
The emerging therapeutic targets for scar management: genetic and epigenetic landscapes
Wound healing is a complex process including hemostasis, inflammation, proliferation, and remodeling during which an orche...
Dexamethasone, a synthetic glucocorticoid, induces the activity of androgen receptor in human dermal papilla cells
Dexamethasone, a synthetic glucocorticoid, induces the activity of androgen receptor in human dermal papilla cells
Psychosocial stress stimulates the secretion of glucocorticoids (GCs), which are stress-related neurohormones. GCs are sec...
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