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Spontaneous activity in peripheral sensory nerves: a systematic review
Spontaneous activity in peripheral sensory nerves: a systematic review
In the peripheral nervous system, spontaneous activity in sensory neurons is considered to be one of
Patient engagement in pain research: no gain without the people in pain
Patient engagement in pain research: no gain without the people in pain
Haroutounian, Simon; Holzer, Katherine J.; Kerns, Robert D.; Veasley, Christin; Dworkin, Robert H.; T...
[11C]-PBR28 positron emission tomography signal as an imaging marker of joint inflammation in knee osteoarthritis
[11C]-PBR28 positron emission tomography signal as an imaging marker of joint inflammation in knee osteoarthritis
Although inflammation is known to play a role in knee osteoarthritis (KOA), inflammation-specific im
Whole-genome methylation profiling reveals regions associated with painful temporomandibular disorders and active recovery processes
Whole-genome methylation profiling reveals regions associated with painful temporomandibular disorders and active recovery processes
Temporomandibular disorders (TMDs), collectively representing one of the most common chronic pain co
Lower individual alpha frequency in individuals with chronic low back pain and fear of movement
Lower individual alpha frequency in individuals with chronic low back pain and fear of movement
Significant progress has been made in linking measures of individual alpha frequency (IAF) and pain.
Remifentanil-induced hyperalgesia in healthy volunteers: a systematic review and meta-analysis of randomized controlled trials
Remifentanil-induced hyperalgesia in healthy volunteers: a systematic review and meta-analysis of randomized controlled trials
Recent literature suggests that the withdrawal of remifentanil (RF) infusion can be associated with
A step towards better understanding chronic overlapping pain conditions
A step towards better understanding chronic overlapping pain conditions
aDepartment of Rheumatology, McGill University, Montreal, QC, Canada bAlan Edwards Pain Management Unit, McGi...
The association between parent mental health and pediatric chronic pain: a systematic review and meta-analysis
The association between parent mental health and pediatric chronic pain: a systematic review and meta-analysis
Mental health problems are common among parents of children with chronic pain and associated with wo
Updated recommendations on measures for clinical trials in pediatric chronic pain: a multiphase approach from the Core Outcomes in Pediatric Persistent Pain (Core-OPPP) Workgroup
Updated recommendations on measures for clinical trials in pediatric chronic pain: a multiphase approach from the Core Outcomes in Pediatric Persistent Pain (Core-OPPP) Workgroup
Many gaps remain in finding effective, safe, and equitable treatments for children and adolescents w
Secondary somatosensory cortex glutamatergic innervation of the thalamus facilitates pain
Secondary somatosensory cortex glutamatergic innervation of the thalamus facilitates pain
Although the secondary somatosensory cortex (SII) is known to be involved in pain perception, its ro
Assessing spontaneous sensory neuron activity using in vivo calcium imaging
Assessing spontaneous sensory neuron activity using in vivo calcium imaging
Heightened spontaneous activity in sensory neurons is often reported in individuals living with chro
Patient engagement in designing, conducting, and disseminating clinical pain research: IMMPACT recommended considerations
Patient engagement in designing, conducting, and disseminating clinical pain research: IMMPACT recommended considerations
In the traditional clinical research model, patients are typically involved only as participants. Ho
The Mas-related G protein–coupled receptor d (Mrgprd) mediates pain hypersensitivity in painful diabetic neuropathy
The Mas-related G protein–coupled receptor d (Mrgprd) mediates pain hypersensitivity in painful diabetic neuropathy
Painful diabetic neuropathy (PDN) is one of the most common and intractable complications of diabete
School bullying and peer relationships in children with chronic pain
School bullying and peer relationships in children with chronic pain
Preliminary evidence suggests that there are significant associations between bullying and chronic p
Duloxetine improves chronic orofacial pain and comorbid depressive symptoms in association with reduction of serotonin transporter protein through upregulation of ubiquitinated serotonin transporter protein
Duloxetine improves chronic orofacial pain and comorbid depressive symptoms in association with reduction of serotonin transporter protein through upregulation of ubiquitinated serotonin transporter protein
Chronic orofacial pain (COP) is relieved by duloxetine (DLX) and frequently causes depressive sympto
New ICD-11 diagnostic criteria for chronic secondary musculoskeletal pain associated with Parkinson disease
New ICD-11 diagnostic criteria for chronic secondary musculoskeletal pain associated with Parkinson disease
aDepartment of Neurology, Center for Neurorehabilitation, Valens, Switzerland bDepartment of Neurology, Phili...
Reply to Cohen et al. (2024): Conditioned pain: fact or fiction?
Reply to Cohen et al. (2024): Conditioned pain: fact or fiction?
aDepartment of Experimental Clinical and Health Psychology, Ghent University, Ghent, Belgium bResearch Group ...
“Conditioned pain” remains unproven and unlikely (comment on Kang et al. PAIN 2023; 164: 2596–2605)
“Conditioned pain” remains unproven and unlikely (comment on Kang et al. PAIN 2023; 164: 2596–2605)
aIndependent Scholar, Sydney, Australia bIndependent Scholar, Perth, Australia cDepartment of Physical ...
Was it “conditioned” or “suggested” pain? Reply to S. Kang et al.
Was it “conditioned” or “suggested” pain? Reply to S. Kang et al.
aDepartment of Medicine and Health Science “Vincenzo Tiberio”, University of Molise, c/o Cardarelli Hospital, Campo...
Reply to Esposto and Cioeta (2023): Clarification regarding classical conditioning and conditioned pain
Reply to Esposto and Cioeta (2023): Clarification regarding classical conditioning and conditioned pain
aDepartment of Experimental Clinical and Health Psychology, Ghent University, Ghent, Belgium bResearch Group ...
Machine learning study of the extended drug–target interaction network informed by pain related voltage-gated sodium channels
Machine learning study of the extended drug–target interaction network informed by pain related voltage-gated sodium channels
Pain is a significant global health issue, and the current treatment options for pain management hav
Machine learning-based identification of determinants for rehabilitation success and future healthcare use prevention in patients with high-grade, chronic, nonspecific low back pain: an individual data 7-year follow-up analysis on 154,167 individuals
Machine learning-based identification of determinants for rehabilitation success and future healthcare use prevention in patients with high-grade, chronic, nonspecific low back pain: an individual data 7-year follow-up analysis on 154,167 individuals
To individually prescribe rehabilitation contents, it is of importance to know and quantify factors
Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain
Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain
The voltage-gated sodium channel NaV1.7 is an essential component of human pain signaling. Changes i
Readiness of nociceptor cell bodies to generate spontaneous activity results from background activity of diverse ion channels and high input resistance
Readiness of nociceptor cell bodies to generate spontaneous activity results from background activity of diverse ion channels and high input resistance
Nociceptor cell bodies generate “spontaneous” discharge that can promote ongoing pain in persistent
Can virtual reality enhance the patient experience during awake invasive procedures? A systematic review of randomized controlled trials
Can virtual reality enhance the patient experience during awake invasive procedures? A systematic review of randomized controlled trials
Procedural anxiety and pain negatively affect surgical outcomes and the patient experience during aw
Effects of virtual reality on psychophysical measures of pain: superiority to imagination and nonimmersive conditions
Effects of virtual reality on psychophysical measures of pain: superiority to imagination and nonimmersive conditions
Virtual reality (VR) has been shown to be effective in pain management. However, to date, little is
Reliability of quantitative sensory testing in the assessment of somatosensory function after high-frequency stimulation–induced sensitisation of central nociceptive pathways
Reliability of quantitative sensory testing in the assessment of somatosensory function after high-frequency stimulation–induced sensitisation of central nociceptive pathways
The high frequency stimulation (HFS) model can be used alongside quantitative sensory testing (QST)
The effect of experimental emotion induction on experimental pain: a systematic review and meta-analysis
The effect of experimental emotion induction on experimental pain: a systematic review and meta-analysis
The idea that emotions can influence pain is generally recognized. However, a synthesis of the numer
Inflammation, lipid dysregulation, and transient receptor potential cation channel subfamily V member 4 signaling perpetuate chronic vulvar pain
Inflammation, lipid dysregulation, and transient receptor potential cation channel subfamily V member 4 signaling perpetuate chronic vulvar pain
Localized provoked vulvodynia is characterized by chronic vulvar pain that disrupts every aspect of
Benign or painful? The interpretation of pain and fear of progression in rheumatoid arthritis
Benign or painful? The interpretation of pain and fear of progression in rheumatoid arthritis
People with chronic pain tend to interpret ambiguous information as health-related, more so than peo
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