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Cannabis use disorder in patients with chronic pain: overestimation and underestimation in a cross-sectional observational study in 3 German pain management centres
Cannabis use disorder in patients with chronic pain: overestimation and underestimation in a cross-sectional observational study in 3 German pain management centres
There are concerns that cannabis use disorder (CUD) may develop in patients with chronic pain prescr
Structural brain connectivity predicts early acute pain after mild traumatic brain injury
Structural brain connectivity predicts early acute pain after mild traumatic brain injury
Mild traumatic brain injury (mTBI), is a leading cause of disability worldwide, with acute pain mani
Enhanced sodium channel inactivation by temperature and FHF2 deficiency blocks heat nociception
Enhanced sodium channel inactivation by temperature and FHF2 deficiency blocks heat nociception
Transient voltage-gated sodium currents are essential for the initiation and conduction of action po
Predictive models for fentanyl dose requirement and postoperative pain using clinical and genetic factors in patients undergoing major breast surgery
Predictive models for fentanyl dose requirement and postoperative pain using clinical and genetic factors in patients undergoing major breast surgery
Fentanyl exhibits interindividual variability in its dose requirement due to various nongenetic and
Novel proresolving lipid mediator mimetic 3-oxa-PD1n-3 docosapentaenoic acid reduces acute and chronic itch by modulating excitatory and inhibitory synaptic transmission and astroglial secretion of lipocalin-2 in mice
Novel proresolving lipid mediator mimetic 3-oxa-PD1n-3 docosapentaenoic acid reduces acute and chronic itch by modulating excitatory and inhibitory synaptic transmission and astroglial secretion of lipocalin-2 in mice
Specialized proresolving mediators (SPMs) have demonstrated potent analgesic actions in animal model
The contribution of endocytosis to sensitization of nociceptors and synaptic transmission in nociceptive circuits
The contribution of endocytosis to sensitization of nociceptors and synaptic transmission in nociceptive circuits
Chronic pain involves sensitization of nociceptors and synaptic transmission of painful signals in n
Placebo effects on cutaneous pain and itch: a systematic review and meta-analysis of experimental results and methodology
Placebo effects on cutaneous pain and itch: a systematic review and meta-analysis of experimental results and methodology
Placebo effects, positive treatment outcomes that go beyond treatment processes, can alter sensation
Resting-state electroencephalography and magnetoencephalography as biomarkers of chronic pain: a systematic review
Resting-state electroencephalography and magnetoencephalography as biomarkers of chronic pain: a systematic review
Reliable and objective biomarkers promise to improve the assessment and treatment of chronic pain. R
Do “central sensitization” questionnaires reflect measures of nociceptive sensitization or psychological constructs? A systematic review and meta-analyses
Do “central sensitization” questionnaires reflect measures of nociceptive sensitization or psychological constructs? A systematic review and meta-analyses
Central sensitization (CS) is defined as an increased nociceptive responsiveness due to sensitizatio
Kappa opioid receptor agonists produce sexually dimorphic and prolactin-dependent hyperalgesic priming
Kappa opioid receptor agonists produce sexually dimorphic and prolactin-dependent hyperalgesic priming
Repeated stress produces hyperalgesic priming in preclinical models, but underlying mechanisms remai
AIBP regulates TRPV1 activation in chemotherapy-induced peripheral neuropathy by controlling lipid raft dynamics and proximity to TLR4 in dorsal root ganglion neurons
AIBP regulates TRPV1 activation in chemotherapy-induced peripheral neuropathy by controlling lipid raft dynamics and proximity to TLR4 in dorsal root ganglion neurons
Nociceptive afferent signaling evoked by inflammation and nerve injury is mediated by the opening of
Structural plasticity of axon initial segment in spinal cord neurons underlies inflammatory pain
Structural plasticity of axon initial segment in spinal cord neurons underlies inflammatory pain
Physiological or pathology-mediated changes in neuronal activity trigger structural plasticity of th
Neuroendocrine mechanisms in oxaliplatin-induced hyperalgesic priming
Neuroendocrine mechanisms in oxaliplatin-induced hyperalgesic priming
Stress plays a major role in the symptom burden of oncology patients and can exacerbate cancer chemo
Huntington-associated protein 1 inhibition contributes to neuropathic pain by suppressing Cav1.2 activity and attenuating inflammation
Huntington-associated protein 1 inhibition contributes to neuropathic pain by suppressing Cav1.2 activity and attenuating inflammation
Although pain dysfunction is increasingly observed in Huntington disease, the underlying mechanisms
Nerve injury increases native CaV2.2 trafficking in dorsal root ganglion mechanoreceptors
Nerve injury increases native CaV2.2 trafficking in dorsal root ganglion mechanoreceptors
Neuronal N-type (CaV2.2) voltage-gated calcium channels are essential for neurotransmission from pri
Towards harmonizing the concepts and definitions of pain in the World Health Organization's Family of International Classifications
Towards harmonizing the concepts and definitions of pain in the World Health Organization's Family of International Classifications
1. Introduction Consistency of language is essential to facilitate high-quality care and patient education, hig...
Molecular taxonomy of nociceptors and pruriceptors
Molecular taxonomy of nociceptors and pruriceptors
1. Introduction The ability to feel the warmth of the sun or the coolness of a breeze on a summer's day; a plea...
The genesis of the unequal burden of pain: a selective review examining social inequities and unheard voices
The genesis of the unequal burden of pain: a selective review examining social inequities and unheard voices
1. Introduction The impact of the COVID-19 pandemic continues to be revealed. It has challenged the healthcare ...
Plasma morphine and morphine-6-glucuronide during chronic morphine therapy for cancer pain: plasma profiles, steady-state concentrations and the consequences of renal failure: erratum
Plasma morphine and morphine-6-glucuronide during chronic morphine therapy for cancer pain: plasma profiles, steady-state concentrations and the consequences of renal failure: erratum
In the above article which published in the October 1991 issue of PAIN, the authors wish to correct a mistake in Table 1. ...
Antibody-induced pain-like behavior and bone erosion: links to subclinical inflammation, osteoclast activity, and acid-sensing ion channel 3–dependent sensitization: erratum
Antibody-induced pain-like behavior and bone erosion: links to subclinical inflammation, osteoclast activity, and acid-sensing ion channel 3–dependent sensitization: erratum
In the above article which published in the August 2022 issue of PAIN, the authors wish to correct a mistake in the acknow...
Stimulated whole-blood cytokine/chemokine responses are associated with interstitial cystitis/bladder pain syndrome phenotypes and features of nociplastic pain: a multidisciplinary approach to the study of chronic pelvic pain research network study
Stimulated whole-blood cytokine/chemokine responses are associated with interstitial cystitis/bladder pain syndrome phenotypes and features of nociplastic pain: a multidisciplinary approach to the study of chronic pelvic pain research network study
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a common and debilitating disease with poor
Chronic temporomandibular disorders are associated with higher propensity to develop central sensitization: a case–control study
Chronic temporomandibular disorders are associated with higher propensity to develop central sensitization: a case–control study
Temporomandibular disorders (TMD) include a group of musculoskeletal disorders that may involve incr
Insights from studying a large cohort of patients
Insights from studying a large cohort of patients
aDepartment of Anesthesiology and Intensive Care, Jena University Hospital, Jena, Germany bDepartment of Anes...
Referred sensation location can be altered by a strong heterotopic nociceptive stimulus: implications for clinical pain conditions
Referred sensation location can be altered by a strong heterotopic nociceptive stimulus: implications for clinical pain conditions
Referred sensations (RS) are a common clinical phenomenon in patients with musculoskeletal pain; how
Predicting placebo analgesia in patients with chronic pain using natural language processing: a preliminary validation study
Predicting placebo analgesia in patients with chronic pain using natural language processing: a preliminary validation study
Patients with chronic pain show large placebo effects in clinical trials, and inert pills can lead t
Patterns of patient outcomes following specialist pain management in Australasia: a latent class analysis using the electronic Persistent Pain Outcomes Collaboration database
Patterns of patient outcomes following specialist pain management in Australasia: a latent class analysis using the electronic Persistent Pain Outcomes Collaboration database
The increasing demand for pain management and limited resources available highlight the need to meas
Pro-opiomelanocortin neurons in the nucleus of the solitary tract mediate endorphinergic endogenous analgesia in mice
Pro-opiomelanocortin neurons in the nucleus of the solitary tract mediate endorphinergic endogenous analgesia in mice
The nucleus of the solitary tract (NTS) contains pro-opiomelanocortin (POMC) neurons that are 1 of t
Dose–response relationship and effect modifier of stabilisation exercises in nonspecific low back pain: a project-wide individual patient data re-analysis on 1483 intervention participants
Dose–response relationship and effect modifier of stabilisation exercises in nonspecific low back pain: a project-wide individual patient data re-analysis on 1483 intervention participants
This planned MiSpEx-Network reanalysis was designed to derive a dose–response relationship under con
Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice
Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice
Descending control of nociception (DCN; also known as conditioned pain modulation [CPM], the behavio
Randomized controlled trial of intrathecal oxytocin on speed of recovery after hip arthroplasty
Randomized controlled trial of intrathecal oxytocin on speed of recovery after hip arthroplasty
Recovery from surgery is quicker in the postpartum period, and this may reflect oxytocin action in t
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