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ANALYSIS OF THE RELATIONSHIP BETWEEN EARLY SERUM PHOSPHATE LEVELS AND SHORT-TERM MORTALITY IN SEPTIC PATIENTS: A RETROSPECTIVE STUDY BASED ON MIMIC-IV
ANALYSIS OF THE RELATIONSHIP BETWEEN EARLY SERUM PHOSPHATE LEVELS AND SHORT-TERM MORTALITY IN SEPTIC PATIENTS: A RETROSPECTIVE STUDY BASED ON MIMIC-IV
Objective: The aim of the study is to explore the impact of early serum phosphate levels on the prog
THE IL-33/ST2 AXIS PROMOTES ACUTE RESPIRATORY DISTRESS SYNDROME BY NATURAL KILLER T CELLS
THE IL-33/ST2 AXIS PROMOTES ACUTE RESPIRATORY DISTRESS SYNDROME BY NATURAL KILLER T CELLS
Acute respiratory distress syndrome (ARDS) is characterized by uncontrolled inflammation, which mani
BODY TEMPERATURE VARIATION AFTER PACKED CELL TRANSFUSION IN ADULT PATIENTS WITH SEPSIS—WHERE WILL THE PENDULUM STOP?
BODY TEMPERATURE VARIATION AFTER PACKED CELL TRANSFUSION IN ADULT PATIENTS WITH SEPSIS—WHERE WILL THE PENDULUM STOP?
Background: Critically ill patients with sepsis often require packed cell transfusions (PCTs). Packe
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS
Blast lung injuries (BLIs) are frequent because of industrial accidents and terrorist groups. Bone m
GLOBAL SIGNATURES OF THE MICROBIOME AND METABOLOME DURING HOSPITALIZATION OF SEPTIC PATIENTS
GLOBAL SIGNATURES OF THE MICROBIOME AND METABOLOME DURING HOSPITALIZATION OF SEPTIC PATIENTS
Background: The gut plays an important role in the development of sepsis and acts as one of the poss
THE EFFECTS OF DNASE I AND LOW-MOLECULAR-WEIGHT HEPARIN IN A MURINE MODEL OF POLYMICROBIAL ABDOMINAL SEPSIS
THE EFFECTS OF DNASE I AND LOW-MOLECULAR-WEIGHT HEPARIN IN A MURINE MODEL OF POLYMICROBIAL ABDOMINAL SEPSIS
Introduction: Cell-free DNA (CFDNA) has emerged as a prognostic biomarker in patients with sepsis. C
THE 19TH CONGRESS OF THE EUROPEAN SHOCK SOCIETY (ESS)
THE 19TH CONGRESS OF THE EUROPEAN SHOCK SOCIETY (ESS)
THE 19TH CONGRESS OF THE EUROPEAN SHOCK SOCIETY (ESS) : Shock &#...
MACROPHAGE SWITCHING: POLARIZATION AND MOBILIZATION AFTER TRAUMA
MACROPHAGE SWITCHING: POLARIZATION AND MOBILIZATION AFTER TRAUMA
Introduction: Trauma alters the immune response in numerous ways, affecting both the innate and adap
ALKBH5 ALLEVIATES HYPOXIA POSTCONDITIONING INJURY IN d-GALACTOSE–INDUCED SENESCENT CARDIOMYOCYTES BY REGULATING STAT3
ALKBH5 ALLEVIATES HYPOXIA POSTCONDITIONING INJURY IN d-GALACTOSE–INDUCED SENESCENT CARDIOMYOCYTES BY REGULATING STAT3
Ischemic postconditioning (I/Post) reduces I/R injury by activating endogenous cardioprotection mech
RISK OF HOSPITAL MORTALITY IN CRITICALLY ILL PATIENTS WITH TRANSIENT AND PERSISTENT THROMBOCYTOPENIA: A RETROSPECTIVE STUDY
RISK OF HOSPITAL MORTALITY IN CRITICALLY ILL PATIENTS WITH TRANSIENT AND PERSISTENT THROMBOCYTOPENIA: A RETROSPECTIVE STUDY
Background: Thrombocytopenia (TP), a common occurrence among patients admitted to the intensive care
LACTATE IMPAIRS VASCULAR PERMEABILITY BY INHIBITING HSPA12B EXPRESSION VIA GPR81-DEPENDENT SIGNALING IN SEPSIS
LACTATE IMPAIRS VASCULAR PERMEABILITY BY INHIBITING HSPA12B EXPRESSION VIA GPR81-DEPENDENT SIGNALING IN SEPSIS
Introduction: Sepsis impaired vascular integrity results in multiple organ failure. Circulating lact
EFFECTS OF 2-METHYL-2-THIAZOLINE ON CIRCULATORY DYNAMICS AND INTESTINAL VASCULAR SYSTEM IN RABBITS WITH ENDOTOXIC SHOCK
EFFECTS OF 2-METHYL-2-THIAZOLINE ON CIRCULATORY DYNAMICS AND INTESTINAL VASCULAR SYSTEM IN RABBITS WITH ENDOTOXIC SHOCK
We hypothesized that circulatory and jejunal mucosal blood flow would improve after 2-methyl-2thiazo
HOSPITAL CHARACTERISTICS ARE ASSOCIATED WITH CLINICAL OUTCOMES IN PATIENTS WITH CARDIOGENIC SHOCK
HOSPITAL CHARACTERISTICS ARE ASSOCIATED WITH CLINICAL OUTCOMES IN PATIENTS WITH CARDIOGENIC SHOCK
Background: Regionalized systems of care for the management of cardiogenic shock (CS) are increasing
A 29-MRNA HOST RESPONSE WHOLE-BLOOD SIGNATURE IMPROVES PREDICTION OF 28-DAY MORTALITY AND 7-DAY INTENSIVE CARE UNIT CARE IN ADULTS PRESENTING TO THE EMERGENCY DEPARTMENT WITH SUSPECTED ACUTE INFECTION AND/OR SEPSIS
A 29-MRNA HOST RESPONSE WHOLE-BLOOD SIGNATURE IMPROVES PREDICTION OF 28-DAY MORTALITY AND 7-DAY INTENSIVE CARE UNIT CARE IN ADULTS PRESENTING TO THE EMERGENCY DEPARTMENT WITH SUSPECTED ACUTE INFECTION AND/OR SEPSIS
Background: Risk stratification of emergency department patients with suspected acute infections and
Necroptosis, Pyroptosis, Ferroptosis in Sepsis and Treatment
Necroptosis, Pyroptosis, Ferroptosis in Sepsis and Treatment
As a global major health problem and a leading cause of death, sepsis is defined as a failure of hom
Selepressin in Septic Shock
Selepressin in Septic Shock
Sepsis and septic shock usually show a high mortality rate and frequently need of intensive care uni
Impaired Lymphocyte Responses in Pediatric Sepsis Vary by Pathogen Type and are Associated with Features of Immunometabolic Dysregulation
Impaired Lymphocyte Responses in Pediatric Sepsis Vary by Pathogen Type and are Associated with Features of Immunometabolic Dysregulation
Background: Sepsis is the leading cause of death in hospitalized children worldwide. Despite its
Circular RNA UBAP2 (hsa_circ_0007367) Correlates with Microcirculatory Perfusion and Predicts Outcomes of Cardiogenic Shock Patients Undergoing Extracorporeal Membrane Oxygenation Support
Circular RNA UBAP2 (hsa_circ_0007367) Correlates with Microcirculatory Perfusion and Predicts Outcomes of Cardiogenic Shock Patients Undergoing Extracorporeal Membrane Oxygenation Support
Background: Severe microcirculatory disturbance is common in patients with cardiogenic shock nece
Exosomal Transfer of DNA Methyl-Transferase mRNA Induces an Immunosuppressive Phenotype in Human Monocytes
Exosomal Transfer of DNA Methyl-Transferase mRNA Induces an Immunosuppressive Phenotype in Human Monocytes
Introduction: Survivors of sepsis exhibit persistent immunosuppression. Epigenetic events may be
Fecal Microbiota Transfer Attenuates Gut Dysbiosis and Functional Deficits After Traumatic Brain Injury
Fecal Microbiota Transfer Attenuates Gut Dysbiosis and Functional Deficits After Traumatic Brain Injury
Background: Traumatic brain injury (TBI) is an underrecognized public health threat. Survivors of
Whole Blood Selective Aortic Arch Perfusion for Exsanguination Cardiac Arrest: Assessing Myocardial Tolerance to the Duration of Cardiac Arrest
Whole Blood Selective Aortic Arch Perfusion for Exsanguination Cardiac Arrest: Assessing Myocardial Tolerance to the Duration of Cardiac Arrest
Introduction: Selective aortic arch perfusion (SAAP) is an endovascular technique that consists o
Defining Sepsis Phenotypes—Two Murine Models of Sepsis and Machine Learning
Defining Sepsis Phenotypes—Two Murine Models of Sepsis and Machine Learning
Introduction: The immunobiology defining the clinically apparent differences in response to sepsi
A Limited Role for AMD3100 Induced Stem Cell Mobilization for Modulation of Thoracic Trauma Outcome
A Limited Role for AMD3100 Induced Stem Cell Mobilization for Modulation of Thoracic Trauma Outcome
Thoracic trauma is a major cause of mortality due to the associated inflammatory acute respiratory d
The Pyruvate Dehydrogenase Complex Mitigates LPS-Induced Endothelial Barrier Dysfunction by Metabolic Regulation
The Pyruvate Dehydrogenase Complex Mitigates LPS-Induced Endothelial Barrier Dysfunction by Metabolic Regulation
Sepsis is a fatal health issue induced by an aberrant host response to infection, and it correlates
Defining Endotheliopathy in Murine Polytrauma Models
Defining Endotheliopathy in Murine Polytrauma Models
Introduction: “Endotheliopathy of trauma” is recognized as endothelial dysfunction following trau
Redox Potential Correlates with Changes in Metabolite Concentrations Attributable to Pathways Active in Oxidative Stress Response in Swine Traumatic Shock
Redox Potential Correlates with Changes in Metabolite Concentrations Attributable to Pathways Active in Oxidative Stress Response in Swine Traumatic Shock
Introduction: Oxidation-reduction (redox) reactions, and the redox potential (RP) that must be ma
A Comprehensive Appraisal of Risk Prediction Models for Cardiogenic Shock
A Comprehensive Appraisal of Risk Prediction Models for Cardiogenic Shock
Despite advances in early revascularization, percutaneous hemodynamic support platforms, and systems
Inflammasome-related Markers upon ICU Admission do not Correlate with Outcome in Critically Ill COVID-19 Patients
Inflammasome-related Markers upon ICU Admission do not Correlate with Outcome in Critically Ill COVID-19 Patients
Purpose: The development of targeted biological therapies for coronavirus disease 2019 (COVID-19)
Contribution of IL-38 in Lung Immunity during Pseudomonas Aeruginosa-induced Pneumonia
Contribution of IL-38 in Lung Immunity during Pseudomonas Aeruginosa-induced Pneumonia
Objective: Interleukin-38 (IL-38), a new type of cytokine, is involved in processes such as tissu
MicroRNA-136-5p from Endothelial Progenitor Cells-released Extracellular Vesicles Mediates TXNIP to Promote the Dissolution of Deep Venous Thrombosis
MicroRNA-136-5p from Endothelial Progenitor Cells-released Extracellular Vesicles Mediates TXNIP to Promote the Dissolution of Deep Venous Thrombosis
Objective: Endothelial progenitor cells-released extracellular vesicles (EPCs-EVs) have previousl
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