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LACTATE IMPAIRS VASCULAR PERMEABILITY BY INHIBITING HSPA12B EXPRESSION VIA GPR81-DEPENDENT SIGNALING IN SEPSIS
LACTATE IMPAIRS VASCULAR PERMEABILITY BY INHIBITING HSPA12B EXPRESSION VIA GPR81-DEPENDENT SIGNALING IN SEPSIS
Introduction: Sepsis impaired vascular integrity results in multiple organ failure. Circulating lact
HOSPITAL CHARACTERISTICS ARE ASSOCIATED WITH CLINICAL OUTCOMES IN PATIENTS WITH CARDIOGENIC SHOCK
HOSPITAL CHARACTERISTICS ARE ASSOCIATED WITH CLINICAL OUTCOMES IN PATIENTS WITH CARDIOGENIC SHOCK
Background: Regionalized systems of care for the management of cardiogenic shock (CS) are increasing
Necroptosis, Pyroptosis, Ferroptosis in Sepsis and Treatment
Necroptosis, Pyroptosis, Ferroptosis in Sepsis and Treatment
As a global major health problem and a leading cause of death, sepsis is defined as a failure of hom
Selepressin in Septic Shock
Selepressin in Septic Shock
Sepsis and septic shock usually show a high mortality rate and frequently need of intensive care uni
Exosomal Transfer of DNA Methyl-Transferase mRNA Induces an Immunosuppressive Phenotype in Human Monocytes
Exosomal Transfer of DNA Methyl-Transferase mRNA Induces an Immunosuppressive Phenotype in Human Monocytes
Introduction: Survivors of sepsis exhibit persistent immunosuppression. Epigenetic events may be
Fecal Microbiota Transfer Attenuates Gut Dysbiosis and Functional Deficits After Traumatic Brain Injury
Fecal Microbiota Transfer Attenuates Gut Dysbiosis and Functional Deficits After Traumatic Brain Injury
Background: Traumatic brain injury (TBI) is an underrecognized public health threat. Survivors of
Defining Sepsis Phenotypes—Two Murine Models of Sepsis and Machine Learning
Defining Sepsis Phenotypes—Two Murine Models of Sepsis and Machine Learning
Introduction: The immunobiology defining the clinically apparent differences in response to sepsi
A Limited Role for AMD3100 Induced Stem Cell Mobilization for Modulation of Thoracic Trauma Outcome
A Limited Role for AMD3100 Induced Stem Cell Mobilization for Modulation of Thoracic Trauma Outcome
Thoracic trauma is a major cause of mortality due to the associated inflammatory acute respiratory d
The Pyruvate Dehydrogenase Complex Mitigates LPS-Induced Endothelial Barrier Dysfunction by Metabolic Regulation
The Pyruvate Dehydrogenase Complex Mitigates LPS-Induced Endothelial Barrier Dysfunction by Metabolic Regulation
Sepsis is a fatal health issue induced by an aberrant host response to infection, and it correlates
Defining Endotheliopathy in Murine Polytrauma Models
Defining Endotheliopathy in Murine Polytrauma Models
Introduction: “Endotheliopathy of trauma” is recognized as endothelial dysfunction following trau
A Comprehensive Appraisal of Risk Prediction Models for Cardiogenic Shock
A Comprehensive Appraisal of Risk Prediction Models for Cardiogenic Shock
Despite advances in early revascularization, percutaneous hemodynamic support platforms, and systems
Inflammasome-related Markers upon ICU Admission do not Correlate with Outcome in Critically Ill COVID-19 Patients
Inflammasome-related Markers upon ICU Admission do not Correlate with Outcome in Critically Ill COVID-19 Patients
Purpose: The development of targeted biological therapies for coronavirus disease 2019 (COVID-19)
Contribution of IL-38 in Lung Immunity during Pseudomonas Aeruginosa-induced Pneumonia
Contribution of IL-38 in Lung Immunity during Pseudomonas Aeruginosa-induced Pneumonia
Objective: Interleukin-38 (IL-38), a new type of cytokine, is involved in processes such as tissu
Thromboelastography for Predicting Disseminated Intravascular Coagulation (DIC) in Sepsis
Thromboelastography for Predicting Disseminated Intravascular Coagulation (DIC) in Sepsis
Department of Critical Care Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India Departm...
What's New in Shock, December 2021?
What's New in Shock, December 2021?
For many of us, this is a time of holidays and giving of gifts. Our authors in this issue of Shock bring us the gift of ex...
What's New in Shock, November 2021?
What's New in Shock, November 2021?
The November issue of SHOCK offers a particularly abundant selection of important reports both in terms of quantity (more ...
What's New in Shock, October 2021?
What's New in Shock, October 2021?
As L.M. Montgomery puts it in her classic children's novel Anne of Green Gables – “I’m so glad I live in a world where the...
What's New in Shock, September 2021?
What's New in Shock, September 2021?
The September issue of Shock covers the wide scope of the Journal, encompassing injury, inflammation, and sepsis: laborato...
What's New in Shock, July 2021?
What's New in Shock, July 2021?
As we enter the summer months, the July issue of Shock offers a refreshing combination of clinical, translational, and bas...
What's New in Shock, June 2021?
What's New in Shock, June 2021?
It is our honor to author the June, “What's New in Shock” commentary as we have the privilege of reviewing an article from...