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Epigenome editing: a novel perspective towards ensuring global food security
Epigenome editing: a novel perspective towards ensuring global food security
The fact that the human population is projected to cross the mark of staggering 8.3 billion by the year 2030 has raised th...
Regulatory crosstalk between TGF-β signaling and miRNAs: a head and neck cancer perspective
Regulatory crosstalk between TGF-β signaling and miRNAs: a head and neck cancer perspective
Cancers originating from mucosal epithelium in the oral cavity, pharynx, larynx, and paranasal sinuses give rise to aggres...
Development of virus-resistant horticultural crops through CRISPR/Cas mediated genome editing: applications and future prospects
Development of virus-resistant horticultural crops through CRISPR/Cas mediated genome editing: applications and future prospects
Fruits and vegetables are sources of essential nutrients and are the cornerstone of balanced human diet. Horticultural cro...
Exploring the association of FTO rs9939609 and SIRT1 rs7069102 genetic variants with obesity: A case–control study in a sample of Pakistani population
Exploring the association of FTO rs9939609 and SIRT1 rs7069102 genetic variants with obesity: A case–control study in a sample of Pakistani population
Disturbances in energy homeostasis may result in positive energy balance and excessive body weight. Susceptibility to this...
Revealing the genomic diversity of North-western Indian people through 20 hypervariable genetic markers
Revealing the genomic diversity of North-western Indian people through 20 hypervariable genetic markers
To explore the genetic diversity within the North-western Indian population, a sample of 216 individuals, selected at rand...
Feeding the future: the role of nanotechnology in tailored nutrition
Feeding the future: the role of nanotechnology in tailored nutrition
With the advent of agriculture, humans kick-started selective processes and catalyzed the unintended development of novel ...
Advancements in bladder cancer detection: a comprehensive review on liquid biopsy and cell-free DNA analysis
Advancements in bladder cancer detection: a comprehensive review on liquid biopsy and cell-free DNA analysis
Bladder cancer (BC) represents a significant global health challenge, contributing to high mortality rates. The progressio...
A comprehensive molecular docking-based study to identify potential drug-candidates against the novel and emerging severe fever with thrombocytopenia syndrome virus (SFTSV) by targeting the nucleoprotein
A comprehensive molecular docking-based study to identify potential drug-candidates against the novel and emerging severe fever with thrombocytopenia syndrome virus (SFTSV) by targeting the nucleoprotein
Severe fever with thrombocytopenia syndrome (SFTS) is a newly emerging haemorrhagic fever that is caused by an RNA virus c...
Epigallocatechin gallate induces an up-regulation of LDLR accompanied by a reduction of idol in Hepg2 cells
Epigallocatechin gallate induces an up-regulation of LDLR accompanied by a reduction of idol in Hepg2 cells
Epigallocatechin gallate (EGCG), the primary catechin in green tea, has improved cholesterol metabolism. However, the mole...
Current approaches and future potential for delivering CRISPR/Cas components in oilseeds and millets
Current approaches and future potential for delivering CRISPR/Cas components in oilseeds and millets
Innovations and novel technologies are essential to address the needs of the future food system. Enhancing the genetics of...
Role of CRISPR/Cas9 based therapy in breast cancer: a future direction
Role of CRISPR/Cas9 based therapy in breast cancer: a future direction
Breast cancer, a prominent contributor to global cancer-related deaths, is a substantial health obstacle for women. Of all...
Do CRISPR-based disease diagnosis methods qualify as point-of-care diagnostics for plant diseases?
Do CRISPR-based disease diagnosis methods qualify as point-of-care diagnostics for plant diseases?
Effective plant disease management calls for a rapid, precise, and a convenient field-deployable method for early diagnosi...
Gene editing tool kit in millets: present status and future directions
Gene editing tool kit in millets: present status and future directions
Millets, the sixth most-grown group of crops in the drylands, support the livelihood of many small-holder farmers in the r...
Identification and validation of defense related candidate genes in Sesamum under artificial inoculation of Macrophomina phaseolina
Identification and validation of defense related candidate genes in Sesamum under artificial inoculation of Macrophomina phaseolina
Sesame (Sesamum indicum L.) suffers significant production loss due to the opportunistic fungus Macrophomina phaseolina wh...
New rules for sharing benefits from the use of digital sequence information
New rules for sharing benefits from the use of digital sequence information
It is important for scientists engaged in genome editing to appreciate that the international community is currently engag...
Limosilactobacillus fermentum LAB212 effectively ameliorates toxigenicity of aflatoxin
Limosilactobacillus fermentum LAB212 effectively ameliorates toxigenicity of aflatoxin
Aflatoxin, the most potent carcinogenic compound produced by Aspergillus flavus, is a common food contaminant. Scientists ...
Directed mutagenesis in plants through genome editing using guide RNA library
Directed mutagenesis in plants through genome editing using guide RNA library
Plants with genetic diversity have a higher rate of resilience and adaptation to environmental change. Crop species need t...
Epigenome editing strategies for plants: a mini review
Epigenome editing strategies for plants: a mini review
Recent development of genome editing (GE) tools has revolutionized crop improvement due to their ability to perform target...
Downregulation of badh2 gene is responsible for aroma in Kon Joha rice (Oryza sativa L.) of Assam
Downregulation of badh2 gene is responsible for aroma in Kon Joha rice (Oryza sativa L.) of Assam
The primary cause of aroma in rice grains is the reduced expression of the badh2 gene, which leads to an accumulation of 2...
Gene editing and therapy in acquired and inherited cardiovascular disorders
Gene editing and therapy in acquired and inherited cardiovascular disorders
Gene editing and therapy holds immense promise in addressing cardiovascular disorders by enabling precise modifications to...
Post-cellular biotic evolution in a nutshell
Post-cellular biotic evolution in a nutshell
The minimum requirements for post-cellular evolution from prokaryotes towards multicellular eukaryotes are outlined. The m...
Cytological variability vis-a-vis cross compatibility in Solanum nigrum (black berry nightshade) and S. villosum (red berry nightshade)
Cytological variability vis-a-vis cross compatibility in Solanum nigrum (black berry nightshade) and S. villosum (red berry nightshade)
The two medicinally potent taxa of genus Solanum, namely S. nigrum and S. villosum are strikingly similar in their phenoty...
Genome editing in peanuts: advancements, challenges and applications
Genome editing in peanuts: advancements, challenges and applications
Genome editing, a powerful technology for precise manipulation of DNA sequences, has revolutionized the field of agricultu...
Targeted genome editing for cotton improvement: prospects and challenges
Targeted genome editing for cotton improvement: prospects and challenges
Cotton is a highly profitable agricultural crop globally, valued for its valuable natural cellulosic fibres, renewable bio...
Assessment of cytotoxic and genotoxic effects of Colletotrichum gloeosporioides and C. capsici toxins on tobacco BY-2 cells
Assessment of cytotoxic and genotoxic effects of Colletotrichum gloeosporioides and C. capsici toxins on tobacco BY-2 cells
Phytopathogenic fungi like Colletotrichum spp. produce toxins composed of an array of host-specific and non-specific compo...
Strategies to utilize genome editing for increasing nitrogen use efficiency in crops
Strategies to utilize genome editing for increasing nitrogen use efficiency in crops
The genome editing techniques have the potential to revolutionize agriculture by enhancing nitrogen use efficiency (NUE) i...
Delineating biomonitoring potential of two crustose lichens Bacidia convexula and B. submedialis through elemental accumulation and microstructural parameters
Delineating biomonitoring potential of two crustose lichens Bacidia convexula and B. submedialis through elemental accumulation and microstructural parameters
Lichens possess unique characteristics, relying on a protective cortex and a filtration mechanism for absorption in the ab...
Cas9 variants expand the targeting scope of base editing systems in bacteria
Cas9 variants expand the targeting scope of base editing systems in bacteria
Base editors (BEs) consist of partially active Cas9 homologs fused to nucleobase-converting DNA deaminases along with cert...
Genome editing based trait improvement in crops: current perspective, challenges and opportunities
Genome editing based trait improvement in crops: current perspective, challenges and opportunities
The exponentially increasing population poses a serious threat to global food security. Concurrently, the climate change c...
Asexual propagation could be an escape to sustain the constraints of inefficient gametic system in the evolving endemic species: evidence from meiotic anomalies encountered in Aponogeton bruggenii (Aponogetonaceae)
Asexual propagation could be an escape to sustain the constraints of inefficient gametic system in the evolving endemic species: evidence from meiotic anomalies encountered in Aponogeton bruggenii (Aponogetonaceae)
The present study deals with the cytogenetics of Aponogeton bruggenii S.R.Yadav and Govekar (Aponogetonaceae) sporting ase...
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