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Ado-trastuzumab emtansine associated spider telangiectasia
Ado-trastuzumab emtansine associated spider telangiectasia
IntroductionBreast cancer is the most common cancer in women. Human epidermal growth factor receptor 2 (HER2) positivity r...
Can pharmacotherapeutic follow-up after allogeneic hematopoietic stem cell transplantation improve medication compliance?
Can pharmacotherapeutic follow-up after allogeneic hematopoietic stem cell transplantation improve medication compliance?
BackgroundAllogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) is currently one of the most effective therapies ...
Cutaneous Stevens Johnson – Toxic Epidermal Necrolysis Immunotherapy related Toxicities in Lung Cancer Patients
Cutaneous Stevens Johnson – Toxic Epidermal Necrolysis Immunotherapy related Toxicities in Lung Cancer Patients
Introduction:New Immuno- Checkpoint inhibitors (ICIs) functioning as PD-1- PDL-1 blockers are nowadays used in a majority ...
Cancer procoagulant inhibitors: New drugs for an old target
Cancer procoagulant inhibitors: New drugs for an old target
1. Wun, T, White, RH. Epidemiology of cancer-related venous thromboembolism. Best Pract Res Clin Haematol 2009; 22: 9–23. ...
Hepatitis B reactivation after oral capecitabine treatment in a rectum cancer patient with isolated anti-HBc IgG positivity
Hepatitis B reactivation after oral capecitabine treatment in a rectum cancer patient with isolated anti-HBc IgG positivity
IntroductionHepatitis B virus (HBV) reactivation in the setting of chemotherapy and immunosuppressive therapy is associate...
Health-related quality of life among cervical cancer patients at Kenyatta National Hospital
Health-related quality of life among cervical cancer patients at Kenyatta National Hospital
BackgroundPrevious study showed that health-related quality of life (HRQoL) was adversely affected during treatment of cer...
Nephrotic syndrome induced by cetuximab in a patient with metastatic colorectal cancer
Nephrotic syndrome induced by cetuximab in a patient with metastatic colorectal cancer
IntroductionCetuximab, an anti-EGFR monoclonal antibody, often cause skin toxicity, most commonly acneiform rash. We prese...
Addressing the Challenges of Novel Oncology and Hematology Treatments Across Sites of Care: Specialty Pharmacy Solutions
Addressing the Challenges of Novel Oncology and Hematology Treatments Across Sites of Care: Specialty Pharmacy Solutions
BackgroundThe number of Food and Drug Administration (FDA) approvals for anticancer therapies has significantly increased ...
Necrotizing leg gangrene from invasive cutaneous Kaposi sarcoma, reversed by pegylated liposomal doxorubicin
Necrotizing leg gangrene from invasive cutaneous Kaposi sarcoma, reversed by pegylated liposomal doxorubicin
IntroductionAlthough rare, Kaposi sarcoma is the most common malignant neoplasm associated with human immunodeficiency vir...
Newly approved anti-CD19 monoclonal antibodies for the treatment of relapsed or refractory diffuse large B-cell lymphoma
Newly approved anti-CD19 monoclonal antibodies for the treatment of relapsed or refractory diffuse large B-cell lymphoma
Objective: This article summarizes the background, clinical trials, and place in therapy for the first two anti-CD19 monoc...
Osimertinib induced cardiac failure and QT-prolongation in a patient with advanced pulmonary adenocarcinoma
Osimertinib induced cardiac failure and QT-prolongation in a patient with advanced pulmonary adenocarcinoma
IntroductionOsimertinib is a third-generation tyrosine kinase inhibitor (TKI) of epidermal growth factor receptor (EGFR) u...
Multiple rechallenges with anti-PD-1 immunotherapy in patients with checkpoint inhibitor-related pneumonitis: A report of two cases
Multiple rechallenges with anti-PD-1 immunotherapy in patients with checkpoint inhibitor-related pneumonitis: A report of two cases
IntroductionWith the expanding use of immune checkpoint inhibitors (ICIs) in patients with various types of cancers, many ...
Veliparib for the treatment of solid malignancies
Veliparib for the treatment of solid malignancies
ObjectiveVeliparib is a poly adenosine diphosphate ribose polymerase (PARP) −1 and −2 inhibitor with chemo-sensitizing and...
Panitumumab Associated Acute Pancreatitis
Panitumumab Associated Acute Pancreatitis
Introduction The addition of panitumumab to chemotherapy in wild-type metastatic colon cancer contributes to survival. Whi...
Chemotherapy-induced neutropenia among breast Cancer patients in a tertiary care hospital: Risk and consequences
Chemotherapy-induced neutropenia among breast Cancer patients in a tertiary care hospital: Risk and consequences
Study objectiveTo identify the risk factors that may predispose breast cancer patients to Chemotherapy-induced neutropenia...
Evaluation of awareness about importance of high fever in leukemia and lymphoma patients receiving chemotherapy among healthcare professionals working in pharmacies other than hospital pharmacies: A survey from a Central Anatolian city
Evaluation of awareness about importance of high fever in leukemia and lymphoma patients receiving chemotherapy among healthcare professionals working in pharmacies other than hospital pharmacies: A survey from a Central Anatolian city
IntroductionPharmacy staff are part of the healthcare delivery. In some cases, the patient goes to the pharmacy before the...
Retrospective study evaluating immune-related adverse events in cancer patients treated with pembrolizumab
Retrospective study evaluating immune-related adverse events in cancer patients treated with pembrolizumab
IntroductionPembrolizumab has been on the market for several years, but most of the safety data is based on clinical trial...
Immediate severe hypersensitivity reaction to etoposide phosphate: Case report and review of the literature
Immediate severe hypersensitivity reaction to etoposide phosphate: Case report and review of the literature
IntroductionHypersensitivity reactions from intravenous (IV) etoposide have been rarely reported, with these being seen mo...
Impact of the insertion of the clinical pharmacist in the Allogeneic Hematopoietic Stem Cells Transplantation team
Impact of the insertion of the clinical pharmacist in the Allogeneic Hematopoietic Stem Cells Transplantation team
IntroductionAllogeneic Hematopoietic Stem Cells Transplantation (allo-HSCT) is capable of curing patients with neoplastic ...
Thrombotic Thrombocytopenic Purpura associated with Pembrolizumab
Thrombotic Thrombocytopenic Purpura associated with Pembrolizumab
IntroductionThrombotic thrombocytopenic purpura (TTP) is a life threatening type of thrombotic microangiopathy (TMA) cause...
Azacitidine-induced massive pericardial effusion in a child with myelodysplastic syndrome
Azacitidine-induced massive pericardial effusion in a child with myelodysplastic syndrome
IntroductionPericardial effusions are rare yet potentially fatal conditions in children. Azacitidine is a DNA-hypomethylat...
Lichen planopilaris-like eruption in chronic myeloid leukemia patient during treatment with nilotinib as second-line therapy
Lichen planopilaris-like eruption in chronic myeloid leukemia patient during treatment with nilotinib as second-line therapy
IntroductionChronic myeloid leukemia (CML) is a malignant clonal disorder of hematopoietic stem cells characterized by a t...
Pro-BNP in the differential diagnosis of dyspnea in patients treated with immune-checkpoint inhibitors: Case Report
Pro-BNP in the differential diagnosis of dyspnea in patients treated with immune-checkpoint inhibitors: Case Report
IntroductionImmune checkpoint inhibitors (ICI) induced cardiac toxicity can present with non-specific symptoms and signs. ...
Progressive Multifocal Leukoencephalopathy Among Ibrutinib Treatment In Chronic Lymphocytic Leukemia
Progressive Multifocal Leukoencephalopathy Among Ibrutinib Treatment In Chronic Lymphocytic Leukemia
Introduction:Both chronic lymphocytic leukemia (CLL) itself and the drugs used for its treatment, pose a risk for progress...
Potential negative pharmacodynamic interaction of spironolactone and abiraterone in two prostate cancer patients
Potential negative pharmacodynamic interaction of spironolactone and abiraterone in two prostate cancer patients
IntroductionSpironolactone when combined with abiraterone in metastatic castration-resistant prostate cancer (mCRPC) may t...
The impact of medication reconciliation and review in patients using oral chemotherapy
The impact of medication reconciliation and review in patients using oral chemotherapy
Background and aimVerifying and reviewing a patients medication list can detect and reduce drug related problems (DRPs). H...
Tyrosine kinase inhibitor nilotinib induced palmoplantar erythrodysesthesia: A rare case
Tyrosine kinase inhibitor nilotinib induced palmoplantar erythrodysesthesia: A rare case
IntroductionNilotinib is a second generation Tyrosine Kinase inhibitor (TKI) used in the treatment of Chronic Myeloid Leuk...
Myocarditis and diaphragmatic rhabdomyolysis with respiratory failure in a patient with metastatic melanoma treated with Nivolumab
Myocarditis and diaphragmatic rhabdomyolysis with respiratory failure in a patient with metastatic melanoma treated with Nivolumab
IntroductionImmunotherapy dramatically changed history of melanoma patients with a clinical benefit never seen before. Nev...
Daratumumab Monotherapy for Heavily Pre-treated and Refractory Myeloma: Results from a UK Multicentre Real World Cohort
Daratumumab Monotherapy for Heavily Pre-treated and Refractory Myeloma: Results from a UK Multicentre Real World Cohort
Daratumumab is the first anti-CD38 targeting monoclonal antibody approved as monotherapy in multiply relapsed myeloma pati...
A pilot study about methods to reduce prescription errors in a chemotherapy day unit – Aspects to consider in pharmacist verification process
A pilot study about methods to reduce prescription errors in a chemotherapy day unit – Aspects to consider in pharmacist verification process
IntroductionPrescribing errors can happen unintentionally during the prescribing process, or when choosing a treatment the...
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