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Antibodies, Vol. 12, Pages 2: The Seroprevalence and Seropositivity of SARS-CoV-2 among Healthcare Workers during the Third Pandemic Wave

Background: Due to the unclear protective role of produced antibodies and the need for seroepidemiologic studies, we surve...

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Antibodies, Vol. 12, Pages 1: Philosophical Approach to Neural Autoantibodies in Psychiatric Disease—Multi-Systemic Dynamic Continuum from Protective to Harmful Autoimmunity in Neuronal Systems

(1) Background: philosophical views are important to enable a general and multi-systemic view of the potential understandi...

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Antibodies, Vol. 11, Pages 78: Delivery of Drugs into Cancer Cells Using Antibody–Drug Conjugates Based on Receptor-Mediated Endocytosis and the Enhanced Permeability and Retention Effect

Innumerable people worldwide die of cancer every year, although pharmaceutical therapy has actualized many benefits in hum...

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Antibodies, Vol. 11, Pages 77: Heparin-Independent and Heparin-Dependent Anti-CXCL4 Antibodies Have a Reciprocal Expression in a Systemic Sclerosis Patients’ Cohort

Systemic sclerosis (SSc) is a chronic disease characterized by skin/internal organ fibrosis, vasculopathy and autoimmunity...

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Antibodies, Vol. 11, Pages 76: SARS-CoV-2 Virus-like Particles (VLPs) Specifically Detect Humoral Immune Reactions in an ELISA-Based Platform

A key in controlling the SARS-CoV-2 pandemic is the assessment of the immune status of the population. We explored the uti...

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Antibodies, Vol. 11, Pages 75: Epitope Mapping of Anti-Mouse CCR3 Monoclonal Antibodies Using Flow Cytometry

The CC chemokine receptor 3 (CCR3) is a receptor for CC chemokines, including CCL5/RANTES, CCL7/MCP-3, and CCL11/eotaxin. ...

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Antibodies, Vol. 11, Pages 74: A Defucosylated Anti-EpCAM Monoclonal Antibody (EpMab-37-mG2a-f) Exerts Antitumor Activity in Xenograft Model

The epithelial cell adhesion molecule (EpCAM) is a stem cell and carcinoma antigen, which mediates cellular adhesion and p...

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Antibodies, Vol. 11, Pages 70: Neutralizing and Total/IgG Spike Antibody Responses Following Homologous CoronaVac vs. BNT162b2 Vaccination Up to 90 Days Post-Booster

Introduction: We documented the total spike antibody (S-Ab), IgG S-Ab and neutralizing antibody (N-Ab) responses of BNT162...

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Antibodies, Vol. 11, Pages 71: Structural Investigation of Therapeutic Antibodies Using Hydroxyl Radical Protein Footprinting Methods

Commercial monoclonal antibodies are growing and important components of modern therapies against a multitude of human dis...

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Antibodies, Vol. 11, Pages 69: Seroprevalence of Anti-SARS-CoV-2 Antibodies in Chattogram Metropolitan Area, Bangladesh

Seroprevalence studies of COVID-19 are used to assess the degree of undetected transmission in the community and different...

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Antibodies, Vol. 11, Pages 67: Rational Design and In Vivo Characterization of mRNA-Encoded Broadly Neutralizing Antibody Combinations against HIV-1

Monoclonal antibodies have been used successfully as recombinant protein therapy; however, for HIV, multiple broadly neutr...

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Antibodies, Vol. 11, Pages 64: Integrating Single Domain Antibodies into Field-Deployable Rapid Assays

Single domain antibodies (sdAb) are the recombinant variable heavy domains derived from camelid heavy-chain antibodies. Wh...

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Antibodies, Vol. 11, Pages 65: IMGT® Nomenclature of Engineered IGHG Variants Involved in Antibody Effector Properties and Formats

The constant region of the immunoglobulin (IG) or antibody heavy gamma chain is frequently engineered to modify the effect...

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Antibodies, Vol. 11, Pages 68: Shared 6mer Peptides of Human and Omicron (21K and 21L) at SARS-CoV-2 Mutation Sites

We investigated the short sequences involving Omicron 21K and Omicron 21L variants to reveal any possible molecular mimicr...

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Antibodies, Vol. 11, Pages 61: Yeast Surface Display Platform for Rapid Selection of an Antibody Library via Sequential Counter Antigen Flow Cytometry

Yeast surface display techniques have been increasingly employed as a tool for both the discovery and affinity maturation ...

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Antibodies, Vol. 11, Pages 66: A Simple Method for the Prediction of Therapeutic Proteins (Monoclonal and Polyclonal Antibodies and Non-Antibody Proteins) for First-in-Pediatric Dose Selection: Application of Salisbury Rule

In order to conduct a pediatric clinical trial, it is important to optimize pediatric dose as accurately as possible. In t...

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Antibodies, Vol. 11, Pages 60: High-Resolution Epitope Mapping and Affinity Binding Analysis Comparing a New Anti-Human LAG3 Rabbit Antibody Clone to the Commonly Used Mouse 17B4 Clone

Lymphocyte activation gene 3 (LAG3) is a T cell inhibitory receptor that promotes tumor cell immune escape and is a potent...

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Antibodies, Vol. 11, Pages 62: IgY Antibodies as Biotherapeutics in Biomedicine

Since the discovery of antibodies by Emil Von Behring and Shibasaburo Kitasato during the 19th century, their potential fo...

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Antibodies, Vol. 11, Pages 59: Investigation of Possible Factors Influencing the Neutralizing Anti-SARS-CoV-2 Antibody Titer after Six Months from the Second Vaccination Dose in a Sample of Italian Nursing Home Personnel

The titer of the anti-SARS-CoV-2 antibodies produced after vaccination shows a relevant decay over time, as demonstrated i...

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Antibodies, Vol. 11, Pages 58: Role of HLA-I Structural Variants and the Polyreactive Antibodies They Generate in Immune Homeostasis

Cell-surface HLA-I molecules consisting of β2-microglobulin (β2m) associated heavy chains (HCs), referre...

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Antibodies, Vol. 11, Pages 57: In Vitro and In Vivo Characterization of a Broadly Neutralizing Anti-SARS-CoV-2 Antibody Isolated from a Semi-Immune Phage Display Library

Neutralizing antibodies targeting the receptor-binding domain (RBD) of SARS-CoV-2 are among the most promising strategies ...

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Antibodies, Vol. 11, Pages 56: Alternative Routes of Administration for Therapeutic Antibodies—State of the Art

Background: For the past two decades, there has been a huge expansion in the development of therapeutic antibodies, with 6...

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Antibodies, Vol. 11, Pages 55: Mitochondrial Autoantibodies and the Role of Apoptosis in Pemphigus Vulgaris

Pemphigus vulgaris (PV) is an IgG autoantibody-mediated, potentially fatal mucocutaneous disease manifested by progressive...

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Antibodies, Vol. 11, Pages 54: Anticalin N- or C-Terminal on a Monoclonal Antibody Affects Both Production and In Vitro Functionality

Bispecific antibodies (BsAbs) represent an important advance in innovative therapeutic strategies. Among the countless for...

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Antibodies, Vol. 11, Pages 53: Quantitation and Identification of Therapeutic Anti-CD22 Monoclonal Antibodies in a Cell-Based ELISA Method

Since they lack native soluble membrane antigens, the analysis and selection of antigen-specific antibodies are commonly p...

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Antibodies, Vol. 11, Pages 52: IgG Avidity Test as a Tool for Discrimination between Recent and Distant Toxoplasma gondii Infection—Current Status of Studies

Toxoplasma gondii, an obligate intracellular protozoan parasite, is the causative agent of one of the most prevalent zoono...

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Antibodies, Vol. 11, Pages 51: On the Rapid Calculation of Binding Affinities for Antigen and Antibody Design and Affinity Maturation Simulations

The accurate and efficient calculation of protein-protein binding affinities is an essential component in antibody and ant...

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Antibodies, Vol. 11, Pages 50: Fc-Dependent Immunomodulation Induced by Antiviral Therapeutic Antibodies: New Perspectives for Eliciting Protective Immune Responses

The multiple mechanisms of action of antiviral monoclonal antibodies (mAbs) have made these molecules a potential therapeu...

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Antibodies, Vol. 11, Pages 49: Therapeutic Potential of Intrabodies for Cancer Immunotherapy: Current Status and Future Directions

Tumor cells are characterized by overexpressed tumor-associated antigens or mutated neoantigens, which are expressed on th...

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Antibodies, Vol. 11, Pages 48: Understanding and Modulating Antibody Fine Specificity: Lessons from Combinatorial Biology

Combinatorial biology methods such as phage and yeast display, suitable for the generation and screening of huge numbers o...

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