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Distribution and volume of mitochondria in alveolar epithelial type 1 cells in infant and adult human lungs
Distribution and volume of mitochondria in alveolar epithelial type 1 cells in infant and adult human lungs
Alveolar epithelial type I (AE1) cells with their wide spatial expansion form approximately 95% of the outer surface area ...
Novel role of curcumin as inhibitor of β-amyloid-induced lamin fragmentation
Novel role of curcumin as inhibitor of β-amyloid-induced lamin fragmentation
Oligomer amyloid beta 42 (Aβ) is considered the key pathogenic molecule in Alzheimer disease (AD) and causes specific...
Complex shape markers can detect alterations in the spatial distribution of cell nuclei in human lung squamous cell carcinoma: a useful tool for automatic analysis?
Complex shape markers can detect alterations in the spatial distribution of cell nuclei in human lung squamous cell carcinoma: a useful tool for automatic analysis?
Lung cancer is the leading cause of cancer-related death. The use of computational methods to quantify changes that are no...
Expression of mRNA for molecules that regulate angiogenesis, endothelial cell survival, and vascular permeability is altered in endothelial cells isolated from db/db mouse hearts
Expression of mRNA for molecules that regulate angiogenesis, endothelial cell survival, and vascular permeability is altered in endothelial cells isolated from db/db mouse hearts
Metabolic syndrome (MetS) is a condition that includes symptoms, such as obesity, hyperglycemia, and hypertension, which e...
Be bold, start cold! cold formalin fixation of colorectal cancer specimens granted superior DNA and RNA quality for downstream molecular analysis
Be bold, start cold! cold formalin fixation of colorectal cancer specimens granted superior DNA and RNA quality for downstream molecular analysis
The use of cold formalin fixation (CFF; i.e., fixating tissue samples with 4 °C precooled formalin) recently...
Identification and culture of functional salivary gland ductal epithelial cells
Identification and culture of functional salivary gland ductal epithelial cells
Sialadenitis is a prevalent salivary gland disease resulting in decreased salivary flow rate. To date, little is known abo...
Specificity of widely used lectins as probed with oligosaccharide and plant polysaccharide arrays
Specificity of widely used lectins as probed with oligosaccharide and plant polysaccharide arrays
Glycan-binding specificity was studied for Jacalin, RCA 120, SBA, PHA-L, PHA-E, WGA, UEA, AAL, LTL, LEL, SNA, DSA, LCA, MA...
Anti-inflammatory and glial response maintain normal colon function in trimethyltin-treated rats
Anti-inflammatory and glial response maintain normal colon function in trimethyltin-treated rats
Studies on the contribution of enteric neuropathy and intestinal homeostasis to central nervous system degeneration using ...
iRhom2 deficiency reduces sepsis-induced mortality associated with the attenuation of lung macrophages in mice
iRhom2 deficiency reduces sepsis-induced mortality associated with the attenuation of lung macrophages in mice
Sepsis has a high mortality rate and leads to multi-organ failure, including lung injury. Inactive rhomboid protease famil...
HOXC10 promotes hypertrophic scar fibroblast fibrosis through the regulation of STMN2 and the TGF-β/Smad signaling pathway
HOXC10 promotes hypertrophic scar fibroblast fibrosis through the regulation of STMN2 and the TGF-β/Smad signaling pathway
The pathophysiology of hypertrophic scar (HS) shares similarities with cancer. HOXC10, a gene significantly involved in ca...
Somatostatin-immunoreactive neurons of the rat gut during the development
Somatostatin-immunoreactive neurons of the rat gut during the development
Somatostatin (SST) is a peptide expressed in the peripheral and central nervous systems, as well as in endocrine and immun...
Expression of SARS-CoV-2 entry molecules ACE2, NRP1, TMPRSS2, and FURIN in the reproductive tissues of male macaques
Expression of SARS-CoV-2 entry molecules ACE2, NRP1, TMPRSS2, and FURIN in the reproductive tissues of male macaques
Coronavirus disease 2019 (COVID-19) reportedly affects male reproductive function by causing spermatogenesis dysfunction a...
MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase–anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte
MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase–anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte
Oocyte meiotic maturation failure and chromosome abnormality is one of the main causes of infertility, abortion, and disea...
Effects of ∆-9 tetrahydrocannabinol on the small intestine altered by high fructose diet: A Histopathological study
Effects of ∆-9 tetrahydrocannabinol on the small intestine altered by high fructose diet: A Histopathological study
The consumption of fructose is increasing day by day. Understanding the impact of increasing fructose consumption on the s...
Establishment of a 3D organoid culture model for the investigation of adult slow-cycling putative intestinal stem cells
Establishment of a 3D organoid culture model for the investigation of adult slow-cycling putative intestinal stem cells
The study of intestinal stem cells is a prerequisite for the development of therapies aimed at regenerating the gut. To en...
Distribution and morphologic characterization of telocytes in rat ovary and uterus: insights from ultrastructural and immunohistochemical analysis
Distribution and morphologic characterization of telocytes in rat ovary and uterus: insights from ultrastructural and immunohistochemical analysis
Telocytes (TCs) are characterized by a small oval-shaped cell body with long prolongations that are called telopods (Tps)....
Stage-specific expression of Toll-like receptors in the seminiferous epithelium of mouse testis
Stage-specific expression of Toll-like receptors in the seminiferous epithelium of mouse testis
Genes encoding Toll-like receptors (TLRs) are expressed by germ cells in the mouse testis. Nevertheless, the expression of...
Immunohistochemical analysis and distribution of epithelial mast cells in the rat larynx and trachea
Immunohistochemical analysis and distribution of epithelial mast cells in the rat larynx and trachea
Mast cells (MCs) in rat airways have been classified into two subtypes: epithelial MCs and connective tissue MCs (CTMCs). ...
FOXM1 requires IDH1 for late genes expression in mitotic cells
FOXM1 requires IDH1 for late genes expression in mitotic cells
Isocitrate dehydrogenase 1 (IDH1) is a metabolic enzyme that converts isocitrate to α-ketoglutarate in cells. However...
Changes in human skin composition due to intrinsic aging: a histologic and morphometric study
Changes in human skin composition due to intrinsic aging: a histologic and morphometric study
Skin represents the main barrier against the external environment, but also plays a role in human relations, as one of the...
Short and long-term 2100 MHz radiofrequency radiation causes endoplasmic reticulum stress in rat testis
Short and long-term 2100 MHz radiofrequency radiation causes endoplasmic reticulum stress in rat testis
Long-term radiofrequency radiation (RFR) exposure, which adversely affects organisms, deteriorates testicular functions. M...
An alternative approach of TUNEL assay to specifically characterize DNA fragmentation in cell model systems
An alternative approach of TUNEL assay to specifically characterize DNA fragmentation in cell model systems
DNA damage is one of the most important effects induced by chemical agents. We report a comparative analysis of DNA fragme...
Studies on the effect of curcumin and quercetin in the liver of male albino rats exposed to gamma irradiation
Studies on the effect of curcumin and quercetin in the liver of male albino rats exposed to gamma irradiation
Ionizing radiation produces deleterious effects on living organisms. The present investigation has been carried out to stu...
Placental neutrophil reverse trans-migration and maternal serum neutrophil extracellular trap expression in HIV infection co-morbid pre-eclampsia in women of African ancestry
Placental neutrophil reverse trans-migration and maternal serum neutrophil extracellular trap expression in HIV infection co-morbid pre-eclampsia in women of African ancestry
Neutrophil extracellular traps (NETs) and placental neutrophil reverse transmigration (r-TM) are implicated in the pathoge...
Sustained inactivation of the Polycomb PRC1 complex induces DNA repair defects and genomic instability in epigenetic tumors
Sustained inactivation of the Polycomb PRC1 complex induces DNA repair defects and genomic instability in epigenetic tumors
Cancer initiation and progression are typically associated with the accumulation of driver mutations and genomic instabili...
Glyoxal-methyl-ethylene sulfonic acid fixative enhances the fixation of cytoskeletal structures for Förster resonance energy transfer measurements
Glyoxal-methyl-ethylene sulfonic acid fixative enhances the fixation of cytoskeletal structures for Förster resonance energy transfer measurements
Förster resonance energy transfer (FRET) serves as a tool for measuring protein–protein interactions using vari...
The emerging role of the semaphorin family in cartilage and osteoarthritis
The emerging role of the semaphorin family in cartilage and osteoarthritis
In the pathogenesis of osteoarthritis, various signaling pathways may influence the bone joint through a common terminal p...
Dynamic chromosome association with nuclear organelles in living cells
Dynamic chromosome association with nuclear organelles in living cells
The development of progressively sophisticated tools complemented by the integration of live cell imaging enhances our und...
Effect of elevated temperature and hydrocortisone addition on the proliferation of fibroblasts
Effect of elevated temperature and hydrocortisone addition on the proliferation of fibroblasts
Hyperthermia along with hydrocortisone (HC) are proven teratogens that can negatively influence embryo development during ...
Visualizing histone H4K20me1 in knock-in mice expressing the mCherry-tagged modification-specific intracellular antibody
Visualizing histone H4K20me1 in knock-in mice expressing the mCherry-tagged modification-specific intracellular antibody
During development and differentiation, histone modifications dynamically change locally and globally, associated with tra...
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