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Ku70 silencing aggravates oxygen–glucose deprivation/reperfusion-induced injury by activation of the p53 apoptotic pathway in rat cortical astrocytes
Ku70 silencing aggravates oxygen–glucose deprivation/reperfusion-induced injury by activation of the p53 apoptotic pathway in rat cortical astrocytes
Oxidative stress-induced DNA damage is an important mechanism that leads to the death of neuronal cells after ischemic str...
Effect of bone marrow niche on hematopoietic stem cells
Effect of bone marrow niche on hematopoietic stem cells
Hematopoietic stem cells (HSCs) reside in a milieu that supports their functions, differentiation, and survival. This nich...
Protective effects of adipose-derived stem cells against testicular injury induced after ischemia–reperfusion by regulating autophagy
Protective effects of adipose-derived stem cells against testicular injury induced after ischemia–reperfusion by regulating autophagy
The damaged organ may experience severe pathological alterations as a result of tissue ischemia–reperfusion (I/R). T...
Effect of middle-age plasma therapy on ileum morphology, immune defense (IgA) and cell proliferation (Ki-67) of female aged rats
Effect of middle-age plasma therapy on ileum morphology, immune defense (IgA) and cell proliferation (Ki-67) of female aged rats
Blood plasma therapy, a new treatment method to eliminate the damage and deterioration caused by aging in many organ syste...
Co-culture of postnatal mouse spinal cord and skeletal muscle explants as an experimental model of neuromuscular interactions
Co-culture of postnatal mouse spinal cord and skeletal muscle explants as an experimental model of neuromuscular interactions
The intercommunication between nerves and muscles plays an important role in the functioning of our body, and its failure ...
A novel tape-free sample preparation method for human osteochondral cryosections for high throughput hyperspectral imaging
A novel tape-free sample preparation method for human osteochondral cryosections for high throughput hyperspectral imaging
Understanding the osteochondral junction, where non-mineralised cartilage and mineralised bone converge, is crucial for jo...
A hypothesis of mesenchymal stem cell osteogenic differentiation mediated by chelidonic acid through the calcium import: original research and computer simulation
A hypothesis of mesenchymal stem cell osteogenic differentiation mediated by chelidonic acid through the calcium import: original research and computer simulation
Chelidonic acid (ChA) is small molecule capable of inducing the differentiation of mesenchymal stem cells (MSCs) into oste...
On the long-term storage of tissue for fluorescence and electron microscopy: lessons learned from rat liver samples
On the long-term storage of tissue for fluorescence and electron microscopy: lessons learned from rat liver samples
Occasionally, tissue samples cannot be processed completely and are stored under varying conditions for extended periods. ...
Cratylia mollis lectin reduces inflammatory burden induced by multidrug-resistant Staphylococcus aureus in diabetic wounds
Cratylia mollis lectin reduces inflammatory burden induced by multidrug-resistant Staphylococcus aureus in diabetic wounds
In diabetes, tissue repair is impaired, increasing susceptibility to Staphylococcus aureus infections, a pathogen commonly...
PD-L1 expression and characterization of its carrier macrophages in placentas with acute and specifically post-SARS-CoV-2 infection
PD-L1 expression and characterization of its carrier macrophages in placentas with acute and specifically post-SARS-CoV-2 infection
At the beginning of the coronavirus disease 2019 (COVID-19) pandemic, uncertainties about the virus and its dangers during...
Fabrication of curcumin-incorporated human amniotic membrane extracellular matrix-derived scaffold to enhance full-thickness wound healing in diabetic rats
Fabrication of curcumin-incorporated human amniotic membrane extracellular matrix-derived scaffold to enhance full-thickness wound healing in diabetic rats
The multifactorial nature of diabetic wounds necessitates a mixed approach for successful treatment. Compensation of degen...
Polycomb protein Bmi1 promotes odontoblast differentiation by accelerating Wnt and BMP signaling pathways
Polycomb protein Bmi1 promotes odontoblast differentiation by accelerating Wnt and BMP signaling pathways
Bmi1 is a polycomb protein localized in stem cells and maintains their stemness. This protein is also reported to regulate...
Characterization of primary cilia in different epithelial cells of thyroid gland
Characterization of primary cilia in different epithelial cells of thyroid gland
The primary cilium (PC) is a biosensor with diverse functions, depending on cellular type. In the thyroid, where it was fi...
The amelioration effects of ankaferd blood stopper, platelet gel, and Momordica charantia on peripheral nerve injury in the rats: a stereological and ultrastructural study
The amelioration effects of ankaferd blood stopper, platelet gel, and Momordica charantia on peripheral nerve injury in the rats: a stereological and ultrastructural study
Peripheral nerve injuries are commonly encountered in clinical practice. Peripheral nerve injuries most commonly result in...
Immunoexpression of placental growth factor (PlGF) and soluble FMS-like tyrosine kinase 1 (sFlt-1) in the placental bed of preeclamptic women of African ancestry living with HIV infection
Immunoexpression of placental growth factor (PlGF) and soluble FMS-like tyrosine kinase 1 (sFlt-1) in the placental bed of preeclamptic women of African ancestry living with HIV infection
Preeclampsia, a severe pregnancy complication linked to defective placentation, poses significant maternal risks and is ch...
Anaplastic thyroid carcinoma: vimentin segregates at the invasive front of tumors in a murine xenograft model
Anaplastic thyroid carcinoma: vimentin segregates at the invasive front of tumors in a murine xenograft model
Anaplastic thyroid carcinoma (ATC) ranks among the most lethal human cancers. Increased migratory and invasive capabilitie...
Mechanisms of S-phase arrest and mitochondrial dysfunction in complex III by DHODH inhibitors in tumorigenic TNBC cells
Mechanisms of S-phase arrest and mitochondrial dysfunction in complex III by DHODH inhibitors in tumorigenic TNBC cells
Dihydroorotate dehydrogenase (DHODH) inhibitors have recently gained increasing research interest owing to their potential...
Distribution and volume of mitochondria in alveolar epithelial type 1 cells in infant and adult human lungs
Distribution and volume of mitochondria in alveolar epithelial type 1 cells in infant and adult human lungs
Alveolar epithelial type I (AE1) cells with their wide spatial expansion form approximately 95% of the outer surface area ...
Novel role of curcumin as inhibitor of β-amyloid-induced lamin fragmentation
Novel role of curcumin as inhibitor of β-amyloid-induced lamin fragmentation
Oligomer amyloid beta 42 (Aβ) is considered the key pathogenic molecule in Alzheimer disease (AD) and causes specific...
Complex shape markers can detect alterations in the spatial distribution of cell nuclei in human lung squamous cell carcinoma: a useful tool for automatic analysis?
Complex shape markers can detect alterations in the spatial distribution of cell nuclei in human lung squamous cell carcinoma: a useful tool for automatic analysis?
Lung cancer is the leading cause of cancer-related death. The use of computational methods to quantify changes that are no...
Expression of mRNA for molecules that regulate angiogenesis, endothelial cell survival, and vascular permeability is altered in endothelial cells isolated from db/db mouse hearts
Expression of mRNA for molecules that regulate angiogenesis, endothelial cell survival, and vascular permeability is altered in endothelial cells isolated from db/db mouse hearts
Metabolic syndrome (MetS) is a condition that includes symptoms, such as obesity, hyperglycemia, and hypertension, which e...
Be bold, start cold! cold formalin fixation of colorectal cancer specimens granted superior DNA and RNA quality for downstream molecular analysis
Be bold, start cold! cold formalin fixation of colorectal cancer specimens granted superior DNA and RNA quality for downstream molecular analysis
The use of cold formalin fixation (CFF; i.e., fixating tissue samples with 4 °C precooled formalin) recently...
Identification and culture of functional salivary gland ductal epithelial cells
Identification and culture of functional salivary gland ductal epithelial cells
Sialadenitis is a prevalent salivary gland disease resulting in decreased salivary flow rate. To date, little is known abo...
Specificity of widely used lectins as probed with oligosaccharide and plant polysaccharide arrays
Specificity of widely used lectins as probed with oligosaccharide and plant polysaccharide arrays
Glycan-binding specificity was studied for Jacalin, RCA 120, SBA, PHA-L, PHA-E, WGA, UEA, AAL, LTL, LEL, SNA, DSA, LCA, MA...
Anti-inflammatory and glial response maintain normal colon function in trimethyltin-treated rats
Anti-inflammatory and glial response maintain normal colon function in trimethyltin-treated rats
Studies on the contribution of enteric neuropathy and intestinal homeostasis to central nervous system degeneration using ...
iRhom2 deficiency reduces sepsis-induced mortality associated with the attenuation of lung macrophages in mice
iRhom2 deficiency reduces sepsis-induced mortality associated with the attenuation of lung macrophages in mice
Sepsis has a high mortality rate and leads to multi-organ failure, including lung injury. Inactive rhomboid protease famil...
HOXC10 promotes hypertrophic scar fibroblast fibrosis through the regulation of STMN2 and the TGF-β/Smad signaling pathway
HOXC10 promotes hypertrophic scar fibroblast fibrosis through the regulation of STMN2 and the TGF-β/Smad signaling pathway
The pathophysiology of hypertrophic scar (HS) shares similarities with cancer. HOXC10, a gene significantly involved in ca...
Somatostatin-immunoreactive neurons of the rat gut during the development
Somatostatin-immunoreactive neurons of the rat gut during the development
Somatostatin (SST) is a peptide expressed in the peripheral and central nervous systems, as well as in endocrine and immun...
Expression of SARS-CoV-2 entry molecules ACE2, NRP1, TMPRSS2, and FURIN in the reproductive tissues of male macaques
Expression of SARS-CoV-2 entry molecules ACE2, NRP1, TMPRSS2, and FURIN in the reproductive tissues of male macaques
Coronavirus disease 2019 (COVID-19) reportedly affects male reproductive function by causing spermatogenesis dysfunction a...
MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase–anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte
MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase–anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte
Oocyte meiotic maturation failure and chromosome abnormality is one of the main causes of infertility, abortion, and disea...
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