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Effect of N-acetylcysteine on hair follicle changes in mouse model of cyclophosphamide-induced alopecia: histological and biochemical study
Effect of N-acetylcysteine on hair follicle changes in mouse model of cyclophosphamide-induced alopecia: histological and biochemical study
Chemotherapy-induced alopecia (CIA) represents one of the most severe side effects of chemotherapy, which forces some pati...
Imaging extrachromosomal DNA (ecDNA) in cancer
Imaging extrachromosomal DNA (ecDNA) in cancer
Extrachromosomal DNA (ecDNA) are circular regions of DNA that are found in many cancers. They are an important means of on...
Antioxidant supplementation may effect DNA methylation patterns, apoptosis, and ROS levels in developing mouse embryos
Antioxidant supplementation may effect DNA methylation patterns, apoptosis, and ROS levels in developing mouse embryos
This study was designed to address the question: does antioxidant-containing embryo culture media affect DNA methyltransfe...
A brief history of the Feulgen reaction
A brief history of the Feulgen reaction
One hundred years ago, Robert Feulgen published a landmark paper in which he described the first method to stain DNA in ce...
Circ_100549 promotes tumor progression in lung adenocarcinoma through upregulation of BIRC6
Circ_100549 promotes tumor progression in lung adenocarcinoma through upregulation of BIRC6
Lung adenocarcinoma (LUAD) is a subtype of lung cancer with high incidence and mortality globally. Emerging evidence sugge...
Chromatin structure and dynamics: one nucleosome at a time
Chromatin structure and dynamics: one nucleosome at a time
Eukaryotic genomes store information on many levels, including their linear DNA sequence, the posttranslational modificati...
Reliable detection of RNA in hippocampus sections of mice by FISH up to a post-mortem delay of 24 h
Reliable detection of RNA in hippocampus sections of mice by FISH up to a post-mortem delay of 24 h
Proteins can be successfully localized in post-mortem (PM) brain tissue sections if the time until PM tissue sampling is n...
Identification of neutrophils and eosinophils in upper airway mucosa with immunofluorescence multiplex image cytometry
Identification of neutrophils and eosinophils in upper airway mucosa with immunofluorescence multiplex image cytometry
Characterization of inflammation in chronic rhinosinusitis with (CRSwNP) and without nasal polyps (CRSsNP) is an ongoing r...
Inhibition of Notch3/Hey1 ameliorates peribiliary hypoxia by preventing hypertrophic hepatic arteriopathy in biliary atresia progression
Inhibition of Notch3/Hey1 ameliorates peribiliary hypoxia by preventing hypertrophic hepatic arteriopathy in biliary atresia progression
Emerging evidence indicates the presence of vascular abnormalities and ischemia in bil...
Increased endocytosis rate and enhanced lysosomal pathway of silica-coated superparamagnetic nanoparticles into M-HeLa cells compared with cultured primary motor neurons
Increased endocytosis rate and enhanced lysosomal pathway of silica-coated superparamagnetic nanoparticles into M-HeLa cells compared with cultured primary motor neurons
The unique properties of superparamagnetic iron oxide nanoparticles (SPIONs) enable their use as magnetic biosensors, targ...
Oxygen levels affect oviduct epithelium functions in air–liquid interface culture
Oxygen levels affect oviduct epithelium functions in air–liquid interface culture
Key reproductive events such as fertilization and early embryonic development occur in the lumen of the oviduct. Since inv...
MOTS-c regulates pancreatic alpha and beta cell functions in vitro
MOTS-c regulates pancreatic alpha and beta cell functions in vitro
The aim of this study is to determine the influence of the mitochondrial open-reading-frame of the twelve S rRNA-c (MOTS-c...
Molecular characterization of ANKRD1 in rhabdomyosarcoma cell lines: expression, localization, and proteasomal degradation
Molecular characterization of ANKRD1 in rhabdomyosarcoma cell lines: expression, localization, and proteasomal degradation
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in children and adolescents. Respecting the age of the pa...
The secretome from human-derived mesenchymal stem cells augments the activity of antitumor plant extracts in vitro
The secretome from human-derived mesenchymal stem cells augments the activity of antitumor plant extracts in vitro
Cancer is understood as a multifactorial disease that involve multiple cell types and phenotypes in the tumor microenviron...
Role of Wisteria floribunda agglutinin binding glycans in carcinogenesis and metastasis of cholangiocarcinoma
Role of Wisteria floribunda agglutinin binding glycans in carcinogenesis and metastasis of cholangiocarcinoma
Aberrant glycosylation is an important factor in facilitating tumor progression and therapeutic resistance. In this study,...
The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study
The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study
Apelin-13 is a peptide hormone that regulates pancreatic endocrine functions, and its benefits on the endocrine pancreas a...
Fibrosis and expression of extracellular matrix proteins in human interventricular septum in aortic valve stenosis and regurgitation
Fibrosis and expression of extracellular matrix proteins in human interventricular septum in aortic valve stenosis and regurgitation
Valvular heart disease leads to ventricular pressure and/or volume overload. Pressure overload leads to fibrosis, which mi...
Effectiveness of cannabidiol (CBD) on histopathological changes and gene expression in hepatocellular carcinoma (HCC) model in male rats: the role of Hedgehog (Hh) signaling pathway
Effectiveness of cannabidiol (CBD) on histopathological changes and gene expression in hepatocellular carcinoma (HCC) model in male rats: the role of Hedgehog (Hh) signaling pathway
The third most prevalent malignancy to cause mortality is hepatocellular carcinoma (HCC). The Hedgehog (Hh) signaling path...
Addressing radiotherapy-induced fibrosis: the potential of platelet-rich plasma and infliximab for improved breast cancer management
Addressing radiotherapy-induced fibrosis: the potential of platelet-rich plasma and infliximab for improved breast cancer management
Breast cancer treatment encompasses various therapeutic modalities, including surgery, radiotherapy, and chemotherapy. Bre...
Studying the topology of peroxisomal acyl-CoA synthetases using self-assembling split sfGFP
Studying the topology of peroxisomal acyl-CoA synthetases using self-assembling split sfGFP
Peroxisomes are membrane-bounded organelles that contain enzymes involved in multiple lipid metabolic pathways. Several of...
The peroxisome: an update on mysteries 3.0
The peroxisome: an update on mysteries 3.0
Peroxisomes are highly dynamic, oxidative organelles with key metabolic functions in cellular lipid metabolism, such as th...
JNK inhibition enhances cell–cell adhesion impaired by desmoglein 3 gene disruption in keratinocytes
JNK inhibition enhances cell–cell adhesion impaired by desmoglein 3 gene disruption in keratinocytes
c-Jun NH2-terminal protein kinase (JNK) and p38 are stress-activated mitogen-activated protein kinases (MAPK) that are pho...
The crucial role of SETDB1 in structural and functional transformation of epithelial cells during regeneration after intestinal ischemia reperfusion injury
The crucial role of SETDB1 in structural and functional transformation of epithelial cells during regeneration after intestinal ischemia reperfusion injury
Su (var) 3–9, enhancer of seste, trithorax (SET)-domain bifurcated histone lysine methyltransferase (SETDB1) plays a...
From complexity to clarity: unravelling tumor heterogeneity through the lens of tumor microenvironment for innovative cancer therapy
From complexity to clarity: unravelling tumor heterogeneity through the lens of tumor microenvironment for innovative cancer therapy
Despite the tremendous clinical successes recorded in the landscape of cancer therapy, tumor heterogeneity remains a formi...
Insulin granule morphology and crinosome formation in mice lacking the pancreatic β cell-specific phogrin (PTPRN2) gene
Insulin granule morphology and crinosome formation in mice lacking the pancreatic β cell-specific phogrin (PTPRN2) gene
We recently reported that phogrin, also known as IA-2β or PTPRN2, forms a complex with the insulin receptor in pancre...
Optimization of PAS stain and similar Schiff’s based methods for glycogen demonstration in liver tissue
Optimization of PAS stain and similar Schiff’s based methods for glycogen demonstration in liver tissue
Demonstration of glycogen in tissue holds considerable diagnostic relevance across various pathological conditions, partic...
Allyl isothiocyanate regulates oxidative stress, inflammation, cell proliferation, cell cycle arrest, apoptosis, angiogenesis, invasion and metastasis via interaction with multiple cell signaling pathways
Allyl isothiocyanate regulates oxidative stress, inflammation, cell proliferation, cell cycle arrest, apoptosis, angiogenesis, invasion and metastasis via interaction with multiple cell signaling pathways
Cancer growth is a molecular mechanism initiated by genetic and epigenetic modifications that are involved in cell prolife...
Placental progesterone and its receptor in HIV-infected pre-eclamptic women
Placental progesterone and its receptor in HIV-infected pre-eclamptic women
Given the high prevalence of HIV infection and pre-eclampsia (PE) in South Africa, this study evaluated and compared the p...
Editorial: Histochemistry and Cell Biology implements new submission guidelines for image presentation and image analysis
Editorial: Histochemistry and Cell Biology implements new submission guidelines for image presentation and image analysis
Journal “Instructions for authors” typically describe in more or less detail how manuscript figures should be prepared for...
Local fractal dimension of collagen detects increased spatial complexity in fibrosis
Local fractal dimension of collagen detects increased spatial complexity in fibrosis
Increase of collagen content and reorganization characterizes fibrosis but quantifying the latter remains challenging. Spa...
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