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Activation of CTU2 expression by LXR promotes the development of hepatocellular carcinoma
Activation of CTU2 expression by LXR promotes the development of hepatocellular carcinoma
Cytosolic thiouridylase 2 (CTU2) is an enzyme modifying transfer RNAs post-transcriptionally, which has been implicated in...
DNA repair deficiencies and neurodegeneration
DNA repair deficiencies and neurodegeneration
Neurodegenerative diseases are the second most prevalent cause of death in industrialized countries. Alzheimer’s Disease i...
Comparison of different sources of mesenchymal stem cells: focus on inflammatory bowel disease
Comparison of different sources of mesenchymal stem cells: focus on inflammatory bowel disease
Inflammatory bowel disease (IBD) poses a significant challenge in modern medicine, with conventional treatments limited by...
Impact of prior antihypertensive treatment on COVID-19 outcomes, by active ingredient
Impact of prior antihypertensive treatment on COVID-19 outcomes, by active ingredient
To assess the impact of prior chronic treatment with angiotensin-converting enzyme inhibitors (ACEIs)/ angiotensin-recepto...
Evaluating the docetaxel effect in an animal model of polyarthritis
Evaluating the docetaxel effect in an animal model of polyarthritis
Rheumatoid arthritis (RA) is immune-mediated, inflammatory disease that affects synovial joints, and characterized by infl...
Genomic stress and impaired DNA repair in Alzheimer disease
Genomic stress and impaired DNA repair in Alzheimer disease
Alzheimer disease (AD) was first described in 1906 by German psychiatrist and neuroanatomist Dr. Alois Alzheimer [1]. In t...
Artemisia herba-alba: antioxidant capacity and efficacy in preventing chronic arthritis in vivo
Artemisia herba-alba: antioxidant capacity and efficacy in preventing chronic arthritis in vivo
Arthritis is a debilitating condition impacting the quality of life for millions worldwide, characterized by pain and infl...
The addition of mammalian cell culture medium impacts nanoparticle toxicity in zebrafish
The addition of mammalian cell culture medium impacts nanoparticle toxicity in zebrafish
Engineered nanomaterials (ENMs) are ubiquitous in contemporary applications, yet their environmental and human health impa...
Maximum tolerated dose and toxicity evaluation of orally administered docetaxel granule in mice
Maximum tolerated dose and toxicity evaluation of orally administered docetaxel granule in mice
Oral delivery of chemotherapy drugs is the most favorable and preferred route of drug administration. However, because of ...
Leveraging low-cost sensors to predict nitrogen dioxide for epidemiologic exposure assessment
Leveraging low-cost sensors to predict nitrogen dioxide for epidemiologic exposure assessment
Statistical models of air pollution enable intra-urban characterization of pollutant concentrations, benefiting exposure a...
The transcriptomic signature of respiratory sensitizers using an alveolar model
The transcriptomic signature of respiratory sensitizers using an alveolar model
Environmental contaminants are ubiquitous in the air we breathe and can potentially cause adverse immunological outcomes s...
CometChip enables parallel analysis of multiple DNA repair activities [DNA repair 106 (2021) 103176–103202]
CometChip enables parallel analysis of multiple DNA repair activities [DNA repair 106 (2021) 103176–103202]
Volume 138, June 2024, 103677Author links open overlay panelJing Ge a, Le P. Ngo a, Simran Kaushal a, Ian J. Tay a, Elina ...
Atopic dermatitis: treatment and innovations in immunotherapy
Atopic dermatitis: treatment and innovations in immunotherapy
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by itching and skin barrier dysfunction. Modera...
YTHDC1 promotes the malignant progression of gastric cancer by promoting ROD1 translocation to the nucleus
YTHDC1 promotes the malignant progression of gastric cancer by promoting ROD1 translocation to the nucleus
RNA-binding proteins (RBPs) make vital impacts on tumor progression and are important potential targets for tumor treatmen...
Administration of Gas6 attenuates lung fibrosis via inhibition of the epithelial-mesenchymal transition and fibroblast activation
Administration of Gas6 attenuates lung fibrosis via inhibition of the epithelial-mesenchymal transition and fibroblast activation
The epithelial-mesenchymal transition (EMT) and fibroblast activation are major events in idiopathic pulmonary fibrosis pa...
Evaluating acute toxicity of amino acid ionic liquids towards Poecilia reticulata fish for designing sustainable chemical processes
Evaluating acute toxicity of amino acid ionic liquids towards Poecilia reticulata fish for designing sustainable chemical processes
An acute toxicity study assessed the LC50 values for eight different amino acid ionic liquids (AAILs), featuring two catio...
Therapeutic effects of tetrandrine in inflammatory diseases: a comprehensive review
Therapeutic effects of tetrandrine in inflammatory diseases: a comprehensive review
Inflammation can be triggered by any factor. The primary pathological manifestations can be summarized as the deterioratio...
Vanillic acid protects mortality and toxicity induced by N-ethyl-N-nitrosourea in mice; in vivo model of chronic lymphocytic leukemia
Vanillic acid protects mortality and toxicity induced by N-ethyl-N-nitrosourea in mice; in vivo model of chronic lymphocytic leukemia
Alkylating agents such as N-Ethyl-N-Nitrosourea (ENU) are ubiquitous within living cells and in the environment. This stud...
Assessing developmental and transcriptional effects of PM2.5 on zebrafish embryos
Assessing developmental and transcriptional effects of PM2.5 on zebrafish embryos
Investigating fine particulate matter (PM2.5) toxicity is crucial for health risk assessment and pollution control. This s...