SCI时时刷

search
+
Art and craft material use patterns by pre-school and elementary school children at home and school: a year long survey for refining exposure assessments
Art and craft material use patterns by pre-school and elementary school children at home and school: a year long survey for refining exposure assessments
Use frequency and times are critical parameters for estimating realistic chemical exposures associated with the use of con...
Integrating NHANES and Toxicity Forecaster Data to Compare Pesticide Exposure and Bioactivity by Farmwork History and US Citizenship
Integrating NHANES and Toxicity Forecaster Data to Compare Pesticide Exposure and Bioactivity by Farmwork History and US Citizenship
medRxiv - The Preprint Server for Health Sciences
High-dose intravenous anakinra treatment is safe and effective in severe and critical COVID-19 patients: a propensity score-matched study in a single center
High-dose intravenous anakinra treatment is safe and effective in severe and critical COVID-19 patients: a propensity score-matched study in a single center
In COVID-19, severe disease course such as need of intensive care unit (ICU) as well as development of mortality is mainly...
Detection of DNA replication errors and 8-oxo-dGTP-mediated mutations in E. coli by Duplex DNA Sequencing
E. coli has been a model organism for genetic analysis for many decades [1], and it is still widely used to gain insights ...
The use of aflibercept (VEGF trap) in mitigating sulfur mustard-induced corneal neovascularization in a rabbit model
Sulfur mustard (SM)-induced ocular injury is characterized by an acute inflammatory response that may become chronic or en...
Pharmacological heat-shock protein inducers and chemical chaperones inhibit upregulation of interleukin-8 by oxidized phospholipids
Pharmacological heat-shock protein inducers and chemical chaperones inhibit upregulation of interleukin-8 by oxidized phospholipids
Oxidised phospholipids such as oxidised palmitoyl-arachidonoyl-phosphatidylcholine (OxPAPC) are increasingly recognised as...
Geographic and demographic variability in serum PFAS concentrations for pregnant women in the United States
Geographic and demographic variability in serum PFAS concentrations for pregnant women in the United States
While major pathways of human PFAS exposure are thought to be drinking water and diet, other pathways and sources have als...
The activation of spliced X-box binding protein 1 by isorhynchophylline therapy improves diabetic encephalopathy
The activation of spliced X-box binding protein 1 by isorhynchophylline therapy improves diabetic encephalopathy
The primary symptom of diabetic encephalopathy (DE), a kind of central diabetic neuropathy caused by diabetes mellitus (DM...
Preparation and characterization of activated carbon from agricultural wastes and their ability to remove chlorpyrifos from water
Chlorpyrifos is an organophosphate insecticide linked to neurological dysfunctions, endocrine disturbance, cardiovascular ...
An assessment of the ECETOC TRA Consumer tool performance as a screening level tool
An assessment of the ECETOC TRA Consumer tool performance as a screening level tool
The European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) Targeted Risk Assessment (TRA) Consumer tool wa...
Implementing a suspect screening method to assess occupational chemical exposures among US-based hairdressers serving an ethnically diverse clientele: a pilot study
Implementing a suspect screening method to assess occupational chemical exposures among US-based hairdressers serving an ethnically diverse clientele: a pilot study
There are over 700,000 hairdressers in the United States, and it is estimated that >90% are female and 31% are Blac...
Low-dose tributyltin triggers human chondrocyte senescence and mouse articular cartilage aging
Low-dose tributyltin triggers human chondrocyte senescence and mouse articular cartilage aging
Tributyltin (TBT) is known as an endocrine-disrupting chemical. This study investigated the effects and possible mechanism...
Development of a transcriptome-based determination of innate immune suppressor (TDIS) assay as an in vitro test for immunotoxicity
Development of a transcriptome-based determination of innate immune suppressor (TDIS) assay as an in vitro test for immunotoxicity
Immunotoxicity has been an important topic in toxicology since inadvertent exposures to xenobiotics were found to alter im...
Applying the adverse outcome pathway concept for assessing non-monotonic dose responses: biphasic effect of bis(2-ethylhexyl) phthalate (DEHP) on testosterone levels
Applying the adverse outcome pathway concept for assessing non-monotonic dose responses: biphasic effect of bis(2-ethylhexyl) phthalate (DEHP) on testosterone levels
Male reproduction is one of the primary health endpoints identified in rodent studies for some phthalates, such as DEHP (B...
Mycotoxins and cellular senescence: the impact of oxidative stress, hypoxia, and immunosuppression
Mycotoxins and cellular senescence: the impact of oxidative stress, hypoxia, and immunosuppression
Mycotoxins induce oxidative stress, hypoxia, and cause immunosuppressive effects. Moreover, emerging evidence show that my...
Perfluoroalkyl substances (PFASs) decrease the expression of recombination-activating genes (RAG1 and RAG2) in human B lymphoma Namalwa cells
Perfluoroalkyl substances (PFASs) decrease the expression of recombination-activating genes (RAG1 and RAG2) in human B lymphoma Namalwa cells
Per- and polyfluoroalkyl substances (PFASs) are omnipresent and have been shown to induce a wide range of adverse effects,...
iNKT17 cells play a pathogenic role in ethinylestradiol-induced cholestatic hepatotoxicity
iNKT17 cells play a pathogenic role in ethinylestradiol-induced cholestatic hepatotoxicity
IL-17 is closely associated with inflammation in intrahepatic cholestasis (IHC). Targeting IL-17 ameliorates IHC in mice. ...
Toxicokinetics of plasmatic VX in a swine model: comparison of a simple enzymatic titration method with a mass spectrometry method
Toxicokinetics of plasmatic VX in a swine model: comparison of a simple enzymatic titration method with a mass spectrometry method
Recent events have shown that organophosphorus nerve agents (OPNAs) are a serious threat. Cholinesterase inhibition by OPN...
Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture
Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture
The prenatal exposure to ethanol (Eth), fluconazole (FLUCO) and sodium valproate (VPA) is related to effects on developmen...
Reply to the opinion paper “The impact of stress on rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide: some theoretical concepts for scientific debate” by Silva et al.
Reply to the opinion paper “The impact of stress on rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide: some theoretical concepts for scientific debate” by Silva et al.
We thank the authors (Silva et al. 2022) for their interest in our paper Social isolation str...
Opioid toxicity: histamine, hypersensitivity, and MRGPRX2
Opioid toxicity: histamine, hypersensitivity, and MRGPRX2
Insights into the pathophysiology of many non-immune-mediated drug reactions referred to as toxicities, sensitivities, int...
CRISPR-based DNA methylation editing of NNT rescues the cisplatin resistance of lung cancer cells by reducing autophagy
CRISPR-based DNA methylation editing of NNT rescues the cisplatin resistance of lung cancer cells by reducing autophagy
Cisplatin is recommended as a first-line chemotherapeutic agent against advanced non-small cell lung cancer (NSCLC), but a...
Organotin and organochlorine toxicants activate key translational regulatory proteins in human immune cells
Organotin and organochlorine toxicants activate key translational regulatory proteins in human immune cells
Environmental contaminant exposures occur due to the widespread use of synthetic chemicals. Tributyltin (TBT), dibutyltin ...
Proactive therapeutic drug monitoring of vincristine in pediatric and adult cancer patients: current supporting evidence and future efforts
Proactive therapeutic drug monitoring of vincristine in pediatric and adult cancer patients: current supporting evidence and future efforts
Vincristine (VCR), an effective antitumor drug, has been utilized in several polytherapy regimens for acute lymphoblastic ...
Isolation of human TRPA1 channel from transfected HEK293 cells and identification of alkylation sites after sulfur mustard exposure
Isolation of human TRPA1 channel from transfected HEK293 cells and identification of alkylation sites after sulfur mustard exposure
Transient receptor potential (TRP) channels are important in the sensing of pain and other stimuli. They may be triggered ...
Histo-anatomical mutilations of developing chick brain induced by in-ovo fluoride and bifenthrin exposure
Comparative developing brain histo-anatomical pathologies of Fluoride ions and Bifenthrin in-ovo exposures were explored i...
Anti-inflammatory and antioxidant activities of Gymnema Sylvestre extract rescue acute respiratory distress syndrome in rats via modulating the NF-κB/MAPK pathway
Anti-inflammatory and antioxidant activities of Gymnema Sylvestre extract rescue acute respiratory distress syndrome in rats via modulating the NF-κB/MAPK pathway
Acute respiratory distress syndrome (ARDS) is one of the major causes of mortality in COVID-19 patients, due to limited th...
Pterostilbene attenuates hemin-induced dysregulation of macrophage M2 polarization via Nrf2 activation in experimental hyperglycemia
Pterostilbene attenuates hemin-induced dysregulation of macrophage M2 polarization via Nrf2 activation in experimental hyperglycemia
Macrophages exhibit a high degree of plasticity that is physiologically relevant in wound healing, and disruption in norma...
Silver nanoparticles exert toxic effects in human monocytes and macrophages associated with the disruption of Δψm and release of pro-inflammatory cytokines
Silver nanoparticles exert toxic effects in human monocytes and macrophages associated with the disruption of Δψm and release of pro-inflammatory cytokines
Silver nanoparticles (AgNP) are the most widely produced type of nanoparticles due to their antimicrobial and preservative...
Interactions of Alcohol and Combination Antiretroviral (cART) drug in Diabetic Male Sprague Dawley Rats: Hippocampal Perturbations and Toxicosis
Hippocampal pathology in diabetes is constantly investigated but the resultant health impact of the concomitant presence o...
阅读更多
format_indent_increase