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Patient-Reported Hair Loss and Its Impacts as Measured by the Alopecia Areata Patient Priority Outcomes Instrument in Patients Treated with Ritlecitinib: The ALLEGRO Phase 2b/3 Randomized Clinical Trial
Patient-Reported Hair Loss and Its Impacts as Measured by the Alopecia Areata Patient Priority Outcomes Instrument in Patients Treated with Ritlecitinib: The ALLEGRO Phase 2b/3 Randomized Clinical Trial
The ALLEGRO phase 2b/3 study investigated the efficacy and safety of ritlecitinib in patients with alopecia areata (AA). T...
From Compression to Itch: Exploring the Link Between Nerve Compression and Neuropathic Pruritus
From Compression to Itch: Exploring the Link Between Nerve Compression and Neuropathic Pruritus
Neuropathic itch is a type of chronic pruritus resulting from neural dysfunction along the afferent pathway. It is often a...
Oral Roflumilast in Patients with Psoriasis: A Real-World Cohort Study
Oral Roflumilast in Patients with Psoriasis: A Real-World Cohort Study
Funding None. Conflicts of ...
Pembrolizumab for the First-Line Treatment of Recurrent Locally Advanced or Metastatic Merkel Cell Carcinoma: Results from the Single-Arm, Open-Label, Phase III KEYNOTE-913 Study
Pembrolizumab for the First-Line Treatment of Recurrent Locally Advanced or Metastatic Merkel Cell Carcinoma: Results from the Single-Arm, Open-Label, Phase III KEYNOTE-913 Study
The phase III KEYNOTE-913 study was conducted to evaluate the efficacy and safety of pembrolizumab as first-line therapy i...
The Potential Role of Cannabidiol in Cosmetic Dermatology: A Literature Review
The Potential Role of Cannabidiol in Cosmetic Dermatology: A Literature Review
Cannabidiol (CBD) is a non-psychotropic cannabinoid with multiple pharmacological properties. Cannabidiol has attracted gr...
Comparing Tretinoin to Other Topical Therapies in the Treatment of Skin Photoaging: A Systematic Review
Comparing Tretinoin to Other Topical Therapies in the Treatment of Skin Photoaging: A Systematic Review
Many morphological and histological changes take place in aging skin. Topical tretinoin is the gold standard anti-aging ag...
Deciphering the Etiologies of Adult Erythroderma: An Updated Guide to Presentations, Diagnostic Tools, Pathophysiologies, and Treatments
Deciphering the Etiologies of Adult Erythroderma: An Updated Guide to Presentations, Diagnostic Tools, Pathophysiologies, and Treatments
Erythroderma, an inflammatory skin condition characterized by widespread erythema with variable degrees of exfoliation, pu...
KECORT Study: An International e-Delphi Study on the Treatment of KEloids Using Intralesional CORTicosteroids in Clinical Practice
KECORT Study: An International e-Delphi Study on the Treatment of KEloids Using Intralesional CORTicosteroids in Clinical Practice
Intralesional corticosteroid administration (ICA) is a first-line keloid treatment. However, it faces significant variabil...
Chronic Hand Eczema
Chronic Hand Eczema
Chronic hand eczema (CHE) is a complex, challenging, and frequently multifactorial skin disease of the hands. It is very c...
Predicting the Time to Relapse Following Withdrawal from Different Biologics in Patients with Psoriasis who Responded to Therapy: A 12-Year Multicenter Cohort Study
Predicting the Time to Relapse Following Withdrawal from Different Biologics in Patients with Psoriasis who Responded to Therapy: A 12-Year Multicenter Cohort Study
For patients with psoriasis, discontinuation of biologics following remission has become more common in daily practice. We...
A Practice Approach to Acne Fulminans in Adolescents
A Practice Approach to Acne Fulminans in Adolescents
Acne fulminans (AF) is a severe form of inflammatory acne commonly associated with adolescents. It is characterized by an ...
Update on Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management
Update on Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the most severe cutaneous adverse reactions ...
Image-Based Artificial Intelligence in Psoriasis Assessment: The Beginning of a New Diagnostic Era?
Image-Based Artificial Intelligence in Psoriasis Assessment: The Beginning of a New Diagnostic Era?
Psoriasis, a chronic inflammatory skin disease, affects millions of people worldwide. It imposes a significant burden on p...
Predictors and Management of Inadequate Response to JAK Inhibitors in Alopecia Areata
Predictors and Management of Inadequate Response to JAK Inhibitors in Alopecia Areata
Alopecia areata is a common autoimmune disorder characterized by non-scarring hair loss on the scalp or other hair-bearing...
Advances in the Application of Noninvasive Skin Imaging Techniques in Acne Scars
Advances in the Application of Noninvasive Skin Imaging Techniques in Acne Scars
Acne scarring is a common sequela of acne vulgaris, which seriously affects facial esthetics. The treatment options for ac...
Human Inborn Errors of Immunity in Pyoderma Gangrenosum: A Systematic Review
Human Inborn Errors of Immunity in Pyoderma Gangrenosum: A Systematic Review
Pyoderma gangrenosum (PG) is a rare ulcerative neutrophilic dermatosis that can be associated with primary immunodeficienc...
Efficacy and Safety of Brodalumab, an Anti-interleukin-17 Receptor A Monoclonal Antibody, for Palmoplantar Pustulosis: 16-Week Results of a Randomized Clinical Trial
Efficacy and Safety of Brodalumab, an Anti-interleukin-17 Receptor A Monoclonal Antibody, for Palmoplantar Pustulosis: 16-Week Results of a Randomized Clinical Trial
Palmoplantar pustulosis (PPP), a refractory skin disease characterized by repeated eruptions of sterile pustules and vesic...
Lichen Planus: What is New in Diagnosis and Treatment?
Lichen Planus: What is New in Diagnosis and Treatment?
Lichen planus (LP), an idiopathic, multifaceted chronic inflammatory disease with a heterogeneous clinical presentation, a...
Sequencing of Targeted Therapy in Psoriasis: Does it Matter?
Sequencing of Targeted Therapy in Psoriasis: Does it Matter?
With the continued development of biologics for the treatment of psoriasis, some patients have achieved optimal control, b...
Association Between Biologic Exposure and the Risk of Depression in Patients with Psoriasis: A Retrospective Analysis of Large US Administrative Claims Data
Association Between Biologic Exposure and the Risk of Depression in Patients with Psoriasis: A Retrospective Analysis of Large US Administrative Claims Data
Funding AbbVie funded the study. AbbVie participated in the study d...
The Current State of Systemic Therapy of Metastatic Uveal Melanoma
The Current State of Systemic Therapy of Metastatic Uveal Melanoma
Uveal melanoma (UM) is genetically a distinct tumor compared to cutaneous melanoma (CM), and due to its low mutational bur...
Integrated Safety Update of Abrocitinib in 3802 Patients with Moderate-to-Severe Atopic Dermatitis: Data from More than 5200 Patient-Years with Up to 4 Years of Exposure
Integrated Safety Update of Abrocitinib in 3802 Patients with Moderate-to-Severe Atopic Dermatitis: Data from More than 5200 Patient-Years with Up to 4 Years of Exposure
Abrocitinib, an oral, once-daily, Janus kinase 1-selective inhibitor, is efficacious in moderate-to-severe atopic dermatit...
Evaluation of the Tolerability of Hedgehog Pathway Inhibitors in the Treatment of Advanced Basal Cell Carcinoma: A Narrative Review of Treatment Strategies
Evaluation of the Tolerability of Hedgehog Pathway Inhibitors in the Treatment of Advanced Basal Cell Carcinoma: A Narrative Review of Treatment Strategies
Hedgehog pathway inhibitors (HHIs) have broadened the treatment options available for patients with advanced basal cell ca...
Adherence to Hidradenitis Suppurativa Treatment
Adherence to Hidradenitis Suppurativa Treatment
Hidradenitis suppurativa (HS) is a chronic, debilitating skin condition that requires multimodal treatment. Adherence rema...
Switching to Interleukin-23 Inhibitors After Ineffectiveness of Ustekinumab: Evaluating Real-World Outcomes in Psoriasis Treatment
Switching to Interleukin-23 Inhibitors After Ineffectiveness of Ustekinumab: Evaluating Real-World Outcomes in Psoriasis Treatment
Funding This study was supported by The University Medical Center S...
Managing the Patient with Psoriasis and Metabolic Comorbidities
Managing the Patient with Psoriasis and Metabolic Comorbidities
Epidemiological data demonstrate strong associations between psoriasis and metabolic comorbidities, including obesity, hyp...
Management and Long-Term Outcomes of Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) in Children: A Scoping Review
Management and Long-Term Outcomes of Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) in Children: A Scoping Review
Drug reaction with eosinophilia and systemic symptoms (DReSS) is known to cause mortality and long-term sequelae in the pe...
Approach to the Atypical Wound
Approach to the Atypical Wound
The heterogeneity of atypical wounds can present diagnostic and therapeutic challenges; however, as the prevalence of atyp...
Dupilumab Safety and Efficacy up to 1 Year in Children Aged 6 Months to 5 Years with Atopic Dermatitis: Results from a Phase 3 Open-Label Extension Study
Dupilumab Safety and Efficacy up to 1 Year in Children Aged 6 Months to 5 Years with Atopic Dermatitis: Results from a Phase 3 Open-Label Extension Study
Pediatric patients with moderate-to-severe atopic dermatitis (AD) often experience a high disease burden and have a high r...
Efficacy, Safety, and Long-Term Disease Control of Ruxolitinib Cream Among Adolescents with Atopic Dermatitis: Pooled Results from Two Randomized Phase 3 Studies
Efficacy, Safety, and Long-Term Disease Control of Ruxolitinib Cream Among Adolescents with Atopic Dermatitis: Pooled Results from Two Randomized Phase 3 Studies
Atopic dermatitis (AD), a highly pruritic, inflammatory skin disease, affects approximately 7% of adolescents globally. A ...
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