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Merkel Cell Carcinoma: Integrating Epidemiology, Immunology, and Therapeutic Updates
Merkel Cell Carcinoma: Integrating Epidemiology, Immunology, and Therapeutic Updates
Merkel cell carcinoma (MCC) is a rare skin cancer characterized by neuroendocrine differentiation. Its carcinogenesis is b...
Ultrasound Surveillance in Melanoma Management: Bridging Diagnostic Promise with Real-World Adherence: A Systematic Review and Meta-Analysis
Ultrasound Surveillance in Melanoma Management: Bridging Diagnostic Promise with Real-World Adherence: A Systematic Review and Meta-Analysis
Ultrasound surveillance has become the new standard of care in stage III melanoma after the 2017 Multicenter Selective Lym...
Secondary Bacterial Infections in Patients with Atopic Dermatitis or Other Common Dermatoses
Secondary Bacterial Infections in Patients with Atopic Dermatitis or Other Common Dermatoses
Secondary bacterial infections of common dermatoses such as atopic dermatitis, ectoparasitosis, and varicella zoster virus...
Early and Sustained Improvements in Symptoms and Quality of Life with Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: 52-Week Results from Two Phase III Randomized Clinical Trials (Measure Up 1 and Measure Up 2)
Early and Sustained Improvements in Symptoms and Quality of Life with Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: 52-Week Results from Two Phase III Randomized Clinical Trials (Measure Up 1 and Measure Up 2)
Atopic dermatitis is a chronic inflammatory disease characterized by increased itch, skin pain, poor sleep quality, and ot...
Tree-Based Machine Learning to Identify Predictors of Psoriasis Incidence at the Neighborhood Level: A Populational Study from Quebec, Canada
Tree-Based Machine Learning to Identify Predictors of Psoriasis Incidence at the Neighborhood Level: A Populational Study from Quebec, Canada
Psoriasis is a major global health burden affecting ~ 60 million people worldwide. Existing studies on psoriasis focused o...
Small-Molecule Inhibitors and Biologics for Palmoplantar Psoriasis and Palmoplantar Pustulosis: A Systematic Review and Network Meta-Analysis
Small-Molecule Inhibitors and Biologics for Palmoplantar Psoriasis and Palmoplantar Pustulosis: A Systematic Review and Network Meta-Analysis
The comparative efficacy of biologics and small-molecule inhibitors in treating palmoplantar psoriasis (PP) and palmoplant...
Rapidly Evolving Pre- and Post-surgical Systemic Treatment of Melanoma
Rapidly Evolving Pre- and Post-surgical Systemic Treatment of Melanoma
With the development of effective BRAF-targeted and immune-checkpoint immunotherapies for metastatic melanoma, clinical tr...
The Impact of Dermatologic Adverse Events on the Quality of Life of Oncology Patients: A Review of the Literature
The Impact of Dermatologic Adverse Events on the Quality of Life of Oncology Patients: A Review of the Literature
Dermatologic adverse events resulting from oncologic therapy are common and negatively impact patients’ quality of l...
Therapeutic Strategies in BRAF V600 Wild-Type Cutaneous Melanoma
Therapeutic Strategies in BRAF V600 Wild-Type Cutaneous Melanoma
There have been many recent advances in melanoma therapy. While 50% of melanomas have a BRAF mutation and are a target for...
Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program
Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program
The ALLEGRO phase 2a and 2b/3 studies demonstrated that ritlecitinib, an oral JAK3/TEC family kinase inhibitor, is efficac...
Treatment of Psoriasis Patients with Latent Tuberculosis Using IL-17 and IL-23 Inhibitors: A Retrospective, Multinational, Multicentre Study
Treatment of Psoriasis Patients with Latent Tuberculosis Using IL-17 and IL-23 Inhibitors: A Retrospective, Multinational, Multicentre Study
Tuberculosis has a major global impact. Immunocompetent hosts usually control this disease, resulting in an asymptomatic l...
The Skin Microbiome and its Significance for Dermatologists
The Skin Microbiome and its Significance for Dermatologists
The skin is a physical and immunological barrier to the external environment. Its large surface area is colonized by diver...
OX40 in the Pathogenesis of Atopic Dermatitis—A New Therapeutic Target
OX40 in the Pathogenesis of Atopic Dermatitis—A New Therapeutic Target
Atopic dermatitis (AD) is a chronic, heterogeneous, inflammatory disease characterized by skin lesions, pruritus, and pain...
Real-World Use of Ruxolitinib Cream: Safety Analysis at 1 Year
Real-World Use of Ruxolitinib Cream: Safety Analysis at 1 Year
Ruxolitinib cream is the first topical Janus kinase (JAK) inhibitor approved in the United States (US) for the treatment o...
Targeted Systemic Therapies for Adults with Atopic Dermatitis: Selecting from Biologics and JAK Inhibitors
Targeted Systemic Therapies for Adults with Atopic Dermatitis: Selecting from Biologics and JAK Inhibitors
Therapeutic options for people with moderate or severe atopic dermatitis refractory to topical therapy have rapidly expand...
Mucocutaneous Manifestations of Recreational Drug Use
Mucocutaneous Manifestations of Recreational Drug Use
Recreational drug use is increasingly common in the dermatology patient population and is often associated with both gener...
Advancements in Bullous Pemphigoid Treatment: A Comprehensive Pipeline Update
Advancements in Bullous Pemphigoid Treatment: A Comprehensive Pipeline Update
Bullous pemphigoid (BP) is a common autoimmune bullous disease affecting mainly the elderly, with rising incidence due to ...
Pressure and Skin: A Review of Disease Entities Driven or Influenced by Mechanical Pressure
Pressure and Skin: A Review of Disease Entities Driven or Influenced by Mechanical Pressure
Skin perceives and reacts to external mechanical forces to create resistance against the external environment. Excessive o...
Pityriasis Rubra Pilaris: An Updated Review of Clinical Presentation, Etiopathogenesis, and Treatment Options
Pityriasis Rubra Pilaris: An Updated Review of Clinical Presentation, Etiopathogenesis, and Treatment Options
Pityriasis rubra pilaris (PRP) is a rare papulosquamous reaction pattern with a significant impact on quality of life. Typ...
Recent Advances in Treatment of Systemic Sclerosis and Morphea
Recent Advances in Treatment of Systemic Sclerosis and Morphea
Systemic sclerosis (SSc) and morphea are autoimmune sclerosing diseases that cause significant morbidity, and in the case ...
Rare Autoinflammatory Neutrophilic Dermatoses in Pregnancy: Literature Review
Rare Autoinflammatory Neutrophilic Dermatoses in Pregnancy: Literature Review
Rare cases of autoinflammatory neutrophilic dermatoses (AINDs) have been reported in patients during pregnancy with associ...
Treat-to-Target in Atopic Dermatitis
Treat-to-Target in Atopic Dermatitis
Atopic dermatitis is one of the most common inflammatory skin diseases among children and adults. Over the last 5 years, t...
Author Correction: Efficacy and Safety of Apremilast for the Treatment of Japanese Patients with Palmoplantar Pustulosis: Results from a Phase 2, Randomized, Placebo-Controlled Study
Author Correction: Efficacy and Safety of Apremilast for the Treatment of Japanese Patients with Palmoplantar Pustulosis: Results from a Phase 2, Randomized, Placebo-Controlled Study
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International ...
Review of Teledermatology: Lessons Learned from the COVID-19 Pandemic
Review of Teledermatology: Lessons Learned from the COVID-19 Pandemic
Utilization of telemedicine for dermatology has greatly expanded since the start of the COVID-19 pandemic, with over 500 n...
Photodynamic Therapy in Treating a Subset of Basal Cell Carcinoma: Strengths, Shortcomings, Comparisons with Surgical Modalities, and Potential Role as Adjunctive Therapy
Photodynamic Therapy in Treating a Subset of Basal Cell Carcinoma: Strengths, Shortcomings, Comparisons with Surgical Modalities, and Potential Role as Adjunctive Therapy
Basal cell carcinoma (BCC) is the most common skin cancer, for which there are multiple treatment options, including the g...
Correction to: Assessment of Efficacy and Safety Outcomes Beyond Week 16 in Clinical Trials of Systemic Agents Used for the Treatment of Moderate to Severe Atopic Dermatitis in Combination with Topical Corticosteroids
Correction to: Assessment of Efficacy and Safety Outcomes Beyond Week 16 in Clinical Trials of Systemic Agents Used for the Treatment of Moderate to Severe Atopic Dermatitis in Combination with Topical Corticosteroids
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International ...
What’s New in Cutaneous T-Cell Lymphoma-Associated Pruritus
What’s New in Cutaneous T-Cell Lymphoma-Associated Pruritus
Cutaneous T-cell lymphomas are a heterogenous group of lymphomas that cause various skin manifestations. Severe pruritus o...
Atopic Dermatitis: Fertility, Pregnancy, and Treatment Perspectives
Atopic Dermatitis: Fertility, Pregnancy, and Treatment Perspectives
Hormonal and immunologic changes during pregnancy can contribute to the development of different dermatoses, the most comm...
Correction to: AtopyReg®, the Prospective Italian Patient Registry for Moderate-to-Severe Atopic Dermatitis in Adults: Baseline Demographics, Disease Characteristics, Comorbidities, and Treatment History
Correction to: AtopyReg®, the Prospective Italian Patient Registry for Moderate-to-Severe Atopic Dermatitis in Adults: Baseline Demographics, Disease Characteristics, Comorbidities, and Treatment History
Dermatology Section, Department of Medicine and Surgery, University of Perugia, Perugia, ItalyLuca Stingeni, Rossella Mari...
Non-invasive Skin Imaging in Cutaneous Lymphomas
Non-invasive Skin Imaging in Cutaneous Lymphomas
The diagnosis of cutaneous lymphomas is challenging and requires skin tissue for histology and immunophenotyping using imm...
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