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Blue Nail Discoloration: Literature Review and Diagnostic Algorithms
Blue Nail Discoloration: Literature Review and Diagnostic Algorithms
Blue nail discoloration is a distinctive clinical presentation, and diagnosis is challenging given the broad differential ...
Correction to: Ruxolitinib Cream 1.5%: A Review in Mild to Moderate Atopic Dermatitis
Correction to: Ruxolitinib Cream 1.5%: A Review in Mild to Moderate Atopic Dermatitis
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International L...
Correction to: Real-Life Barriers to Diagnosis of Early Mycosis Fungoides: An International Expert Panel Discussion
Correction to: Real-Life Barriers to Diagnosis of Early Mycosis Fungoides: An International Expert Panel Discussion
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International L...
Treatment Strategies for Chronic Pruritus and Eczema/Dermatitis in Older Adults Under the Category of Chronic Eczematous Eruptions of Aging (CEEA)
Treatment Strategies for Chronic Pruritus and Eczema/Dermatitis in Older Adults Under the Category of Chronic Eczematous Eruptions of Aging (CEEA)
Chronic eczematous eruptions of aging (CEEA) refers to a heterogenous group of longstanding, pruritic eczematous dermatose...
Treatment of Recurrent Melanoma Following Adjuvant Therapy
Treatment of Recurrent Melanoma Following Adjuvant Therapy
In the era of effective therapies in melanoma, notably the widespread use of two types of adjuvant treatments: anti-PD-1 i...
Stepping Down Treatment in Chronic Spontaneous Urticaria: What We Know and What We Don’t Know
Stepping Down Treatment in Chronic Spontaneous Urticaria: What We Know and What We Don’t Know
In chronic spontaneous urticaria (CSU), wheals, angioedema, or both appear spontaneously for > 6 weeks. Cu...
Efficacy and Safety of Baricitinib in Patients with Severe Alopecia Areata over 52 Weeks of Continuous Therapy in Two Phase III Trials (BRAVE-AA1 and BRAVE-AA2)
Efficacy and Safety of Baricitinib in Patients with Severe Alopecia Areata over 52 Weeks of Continuous Therapy in Two Phase III Trials (BRAVE-AA1 and BRAVE-AA2)
The oral Janus kinase (JAK) inhibitor baricitinib has demonstrated efficacy for severe alopecia areata (AA) over 36 weeks....
Efficacy and Safety of Dupilumab Maintained in Adults ≥ 60 Years of Age with Moderate-to-Severe Atopic Dermatitis: Analysis of Pooled Data from Four Randomized Clinical Trials
Efficacy and Safety of Dupilumab Maintained in Adults ≥ 60 Years of Age with Moderate-to-Severe Atopic Dermatitis: Analysis of Pooled Data from Four Randomized Clinical Trials
Adults aged ≥ 60 years are often underrepresented in atopic dermatitis (AD) clinical trials; age-related comorbiditi...
Stasis Dermatitis: An Overview of Its Clinical Presentation, Pathogenesis, and Management
Stasis Dermatitis: An Overview of Its Clinical Presentation, Pathogenesis, and Management
Stasis dermatitis is a chronic inflammatory skin disease of the lower extremities. It typically occurs in older individual...
Efficacy and Safety of Sonic Hedgehog Inhibitors in Basal Cell Carcinomas: An Updated Systematic Review and Meta-analysis (2009–2022)
Efficacy and Safety of Sonic Hedgehog Inhibitors in Basal Cell Carcinomas: An Updated Systematic Review and Meta-analysis (2009–2022)
Basal cell carcinoma (BCC) of the skin is the most common form of skin cancer in the United States. In life-threatening, a...
Review of Laser Treatments for Post-Inflammatory Hyperpigmentation in Skin of Color
Review of Laser Treatments for Post-Inflammatory Hyperpigmentation in Skin of Color
Post-inflammatory hyperpigmentation is an extremely common disorder of pigmentation in skin of color. It most frequently a...
Effects of Exercise and Dietary Modifications on Hidradenitis Suppurativa: A Systematic Review
Effects of Exercise and Dietary Modifications on Hidradenitis Suppurativa: A Systematic Review
Hidradenitis suppurativa affects up to 4% of the population worldwide. Many treatment options exist but these come with a ...
Patient-Reported Outcome Measures and Their Clinical Applications in Dermatology
Patient-Reported Outcome Measures and Their Clinical Applications in Dermatology
With more disease- and symptom-specific measures available and research pointing to increased usefulness, patient-reported...
Vitiligo Treatments: Review of Current Therapeutic Modalities and JAK Inhibitors
Vitiligo Treatments: Review of Current Therapeutic Modalities and JAK Inhibitors
Vitiligo is a chronic autoimmune disease characterized by loss of pigment of the skin, affecting 0.5–2% of the popul...
Muir–Torre Syndrome: A Cutaneous Finding Amidst Broader Malignancies
Muir–Torre Syndrome: A Cutaneous Finding Amidst Broader Malignancies
Muir–Torre syndrome (MTS) is a rare autosomal dominant genetic condition resulting from microsatellite instability w...
Syphilis in Dermatology: Recognition and Management
Syphilis in Dermatology: Recognition and Management
The incidence of syphilis has been increasing in the USA since 2000. Notably, the coronavirus disease 2019 pandemic negati...
Alcohol and Smoking Cessation as Potential Modulators for Smoking-Associated Psoriasis Risk in Postmenopausal Women: The Women’s Health Initiative
Alcohol and Smoking Cessation as Potential Modulators for Smoking-Associated Psoriasis Risk in Postmenopausal Women: The Women’s Health Initiative
The association of alcohol with psoriasis has been inconsistent among studies. We aimed (1) to determine whether alcohol c...
Hypertrophic Scars and Keloids: Advances in Treatment and Review of Established Therapies
Hypertrophic Scars and Keloids: Advances in Treatment and Review of Established Therapies
Hypertrophic scars and keloids can have significant detrimental effects on patients both psychosocially and functionally. ...
Review of an Anti-CD20 Monoclonal Antibody for the Treatment of Autoimmune Diseases of the Skin
Review of an Anti-CD20 Monoclonal Antibody for the Treatment of Autoimmune Diseases of the Skin
Biologic therapies targeting B-cells are emerging as an effective strategy to treat a variety of immune-mediated diseases....
Acknowledgment to Referees
Acknowledgment to Referees
Welcome to the first issue of the American Journal of Clinical Dermatology for 2023.I wish to...
The Impact of Hyperhidrosis on Quality of Life: A Review of the Literature
The Impact of Hyperhidrosis on Quality of Life: A Review of the Literature
Hyperhidrosis is a condition of excessive sweating, which can have profound physical and mental effects. Hyperhidrosis is ...
Development of Cutaneous T-Cell Lymphoma Following Biologic Treatment: A Systematic Review
Development of Cutaneous T-Cell Lymphoma Following Biologic Treatment: A Systematic Review
Cutaneous T-cell lymphoma following biologic therapy is extremely rare. The aim of this systematic review was to investiga...
Ruxolitinib Cream 1.5%: A Review in Mild to Moderate Atopic Dermatitis
Ruxolitinib Cream 1.5%: A Review in Mild to Moderate Atopic Dermatitis
Ruxolitinib cream 1.5% (OPZELURA™) is a topical formulation of ruxolitinib, a potent, selective inhibitor of Janus k...
Truncal Acne and Scarring: A Comprehensive Review of Current Medical and Cosmetic Approaches to Treatment and Patient Management
Truncal Acne and Scarring: A Comprehensive Review of Current Medical and Cosmetic Approaches to Treatment and Patient Management
Acne vulgaris is one of the most common skin disorders worldwide. It typically affects skin areas with a high density of s...
Early Itch Response with Abrocitinib Is Associated with Later Efficacy Outcomes in Patients with Moderate-to-Severe Atopic Dermatitis: Subgroup Analysis of the Randomized Phase III JADE COMPARE Trial
Early Itch Response with Abrocitinib Is Associated with Later Efficacy Outcomes in Patients with Moderate-to-Severe Atopic Dermatitis: Subgroup Analysis of the Randomized Phase III JADE COMPARE Trial
Abrocitinib, an oral Janus kinase 1 inhibitor, provided significant itch relief by week 2 in patients with moderate-to-sev...
The Current Treatment Landscape of Cutaneous Squamous Cell Carcinoma
The Current Treatment Landscape of Cutaneous Squamous Cell Carcinoma
Non-melanoma skin cancers (NMSCs) are the most common form of skin cancer worldwide. The global incidence of cutaneous squ...
Pharmacokinetics of Roflumilast Cream in Chronic Plaque Psoriasis: Data from Phase I to Phase III Studies
Pharmacokinetics of Roflumilast Cream in Chronic Plaque Psoriasis: Data from Phase I to Phase III Studies
Most patients with chronic plaque psoriasis receive topical treatment; however, available options lack a balance of effica...
Beyond the Hot Comb: Updates in Epidemiology, Pathogenesis, and Treatment of Central Centrifugal Cicatricial Alopecia from 2011 to 2021
Beyond the Hot Comb: Updates in Epidemiology, Pathogenesis, and Treatment of Central Centrifugal Cicatricial Alopecia from 2011 to 2021
Central centrifugal cicatricial alopecia (CCCA) is a form of scarring alopecia that predominantly affects middle-aged wome...
Real-Life Barriers to Diagnosis of Early Mycosis Fungoides: An International Expert Panel Discussion 
Real-Life Barriers to Diagnosis of Early Mycosis Fungoides: An International Expert Panel Discussion 
Mycosis fungoides (MF) is a rare, primary cutaneous T-cell lymphoma that is challenging to diagnose due to its heterogeneo...
Effect of Roflumilast Cream (ARQ-151) on Itch and Itch-Related Sleep Loss in Adults with Chronic Plaque Psoriasis: Patient-Reported Itch Outcomes of a Phase 2b Trial
Effect of Roflumilast Cream (ARQ-151) on Itch and Itch-Related Sleep Loss in Adults with Chronic Plaque Psoriasis: Patient-Reported Itch Outcomes of a Phase 2b Trial
Itch is the most bothersome symptom reported by patients with psoriasis. Safe and effective treatments for psoriasis that ...
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