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Developing generic templates to shape the future for conducting integrated research platform trials
Developing generic templates to shape the future for conducting integrated research platform trials
Interventional clinical studies conducted in the regulated drug research environment are designed using International Coun...
Investigating the use of finerenone in children with chronic kidney disease and proteinuria: design of the FIONA and open-label extension studies
Investigating the use of finerenone in children with chronic kidney disease and proteinuria: design of the FIONA and open-label extension studies
Proteinuria is a modifiable risk factor for chronic kidney disease (CKD) progression in children. Finerenone, a selective,...
Engaging Fathers for Effective Child Nutrition and Development in Tanzania (EFFECTS): study protocol for a five-arm, cluster-randomized trial
Engaging Fathers for Effective Child Nutrition and Development in Tanzania (EFFECTS): study protocol for a five-arm, cluster-randomized trial
Globally, 144 million children under 5 years are undernourished and 250 million do not meet their developmental potential....
Estimands for clinical endpoints in tuberculosis treatment randomized controlled trials: a retrospective application in a completed trial
Estimands for clinical endpoints in tuberculosis treatment randomized controlled trials: a retrospective application in a completed trial
Randomized trials for the treatment of tuberculosis (TB) rely on a composite primary outcome to capture unfavorable treatm...
EFFects of Exposure and Cognitive behavioral Therapy for chronic BACK pain (“EFFECT-BACK”): study protocol for a randomized controlled trial
EFFects of Exposure and Cognitive behavioral Therapy for chronic BACK pain (“EFFECT-BACK”): study protocol for a randomized controlled trial
Chronic back pain is a widespread medical condition associated with high socioeconomic costs and increasing prevalence. De...
Transdiagnostic and tailored internet intervention to improve mental health among university students: Research protocol for a randomized controlled trial
Transdiagnostic and tailored internet intervention to improve mental health among university students: Research protocol for a randomized controlled trial
Emerging adulthood is often associated with mental health problems. About one in three university students report symptoms...
Study protocol: a core outcome set for perioperative exercise clinical effectiveness trials for lung cancer patients
Study protocol: a core outcome set for perioperative exercise clinical effectiveness trials for lung cancer patients
Outcome assessment in perioperative exercise trials for lung cancer is heterogeneous, often omitting those that are import...
Coenzyme Q10 supplementation in burn patients: a double-blind placebo-controlled randomized clinical trial
Coenzyme Q10 supplementation in burn patients: a double-blind placebo-controlled randomized clinical trial
Burn injuries are important medical problems that, aside from skin damage, cause a systemic response including inflammatio...