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Functional metagenomic analysis reveals potential inflammatory triggers associated with genetic risk for autoimmune disease
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Immune-mediated necrotizing myopathy: A comprehensive review of the pathogenesis, clinical features, and treatments
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Impact of coding risk variant IFNGR2 on the B cell-intrinsic IFN-γ signaling pathway in multiple sclerosis
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Soluble form of immune checkpoints in autoimmune diseases
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Reconstituted CD74+ NK cells trigger chronic graft versus host disease after allogeneic bone marrow transplantation
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Cellular pathways and molecular events that shape autoantibody production in COVID-19
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Inflammation dynamically regulates steroid hormone metabolism and action within macrophages in rheumatoid arthritis
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Pin1 maintains the effector program of pathogenic Th17 cells in autoimmune neuroinflammation
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Adding salt to foods and risk of psoriasis: A prospective cohort study
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Successful long-term systemic sclerosis treatment by high-frequent low-dose B cell-depleting therapy
Successful long-term systemic sclerosis treatment by high-frequent low-dose B cell-depleting therapy
ObjectivesSystemic sclerosis (SSc) is a multiorgan disease with a 10-year mortality rate of up to 50 %. B cell-depleting t...
Cannabinoid receptor 2 selective agonist alleviates systemic sclerosis by inhibiting Th2 differentiation through JAK/SOCS3 signaling
Cannabinoid receptor 2 selective agonist alleviates systemic sclerosis by inhibiting Th2 differentiation through JAK/SOCS3 signaling
Systemic sclerosis (SSc) is a rare disease that affects approximately 10–20 individuals per million each year. It is chara...
Autoreactivity to self-antigens LL37 and ADAMTSL5 influences the clinical response to risankizumab in psoriatic patients
Autoreactivity to self-antigens LL37 and ADAMTSL5 influences the clinical response to risankizumab in psoriatic patients
Psoriasis is a chronic inflammatory skin disease affecting 2–3% of individuals in Europe and 4 % in USA [1]. It is mediate...
The autoimmune response induced by α-synuclein peptides drives neuronal cell death and glial cell activation
The autoimmune response induced by α-synuclein peptides drives neuronal cell death and glial cell activation
Parkinson's disease (PD) is a progressive neurodegenerative disorder associated with the loss of dopaminergic neurons and ...
Immune interplay from circulation to local lesion in pemphigus pathogenesis
Immune interplay from circulation to local lesion in pemphigus pathogenesis
Pemphigus is the typical autoimmune blistering disease (AIBD) caused by pathogenic autoantibodies targeting to the keratin...
Outcome and prognosis of isolated carotid vasculitis
Outcome and prognosis of isolated carotid vasculitis
MethodsWe performed a retrospective multicenter study of 36 patients (median age at diagnosis was 37 [IQR 27–45] years and...
Microchimeric cells promote production of rheumatoid arthritis-specific autoantibodies
Microchimeric cells promote production of rheumatoid arthritis-specific autoantibodies
Volume 146, June 2024, 103238Author links open overlay panel, , , , , , Highlights•DBA/2 mice “unable” to produce RA-speci...
Decoding CD4+ T cell transcriptome in giant cell arteritis: Novel pathways and altered cross-talk with monocytes
Decoding CD4+ T cell transcriptome in giant cell arteritis: Novel pathways and altered cross-talk with monocytes
BackgroundGiant cell arteritis (GCA) is an immune-mediated large-vessels vasculitis with complex etiology. Although the pa...
CD72 is an inhibitory pattern recognition receptor that recognizes ribosomes and suppresses production of anti-ribosome autoantibody
CD72 is an inhibitory pattern recognition receptor that recognizes ribosomes and suppresses production of anti-ribosome autoantibody
Systemic lupus erythematosus (SLE) is characterized by the production of autoantibodies to a vast array of self-antigens p...
Natural IgG protects against early dissemination of vesicular stomatitis virus
Natural IgG protects against early dissemination of vesicular stomatitis virus
Volume 146, June 2024, 103230Author links open overlay panel, , , , , , , , Highlights•FcRn deficiency minimally impacted ...