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Comprehensive genomic profiling for advanced hepatocellular carcinoma in clinical practice
Comprehensive genomic profiling for advanced hepatocellular carcinoma in clinical practice
Although several therapeutic agents show efficacy in advanced hepatocellular carcinoma (HCC), biomarkers such as comprehen...
Non-cirrhotic portal fibrosis/idiopathic portal hypertension: APASL recommendations for diagnosis and management
Non-cirrhotic portal fibrosis/idiopathic portal hypertension: APASL recommendations for diagnosis and management
Since the Asian Pacific Association for the Study of the Liver (APASL) published guidelines on non-cirrhotic portal fibros...
Optimal threshold of portal pressure gradient for patients with ascites after covered TIPS: a multicentre cohort study
Optimal threshold of portal pressure gradient for patients with ascites after covered TIPS: a multicentre cohort study
Transjugular intrahepatic portosystemic shunt (TIPS) is recommended for treating recurrent and refractory ascites. However...
Impact of graft type on outcomes following liver transplantation for primary sclerosing cholangitis
Impact of graft type on outcomes following liver transplantation for primary sclerosing cholangitis
Limited data exists regarding impact of graft type on outcomes following liver transplantation (LT) in Primary Sclerosing ...
Metabolic (dysfunction)-associated fatty liver disease metrics and contributions to liver research
Metabolic (dysfunction)-associated fatty liver disease metrics and contributions to liver research
The international consensus to revise non-alcoholic fatty liver disease to metabolic (dysfunction)-associated fatty liver ...
Adipokine/hepatokines profiling of fatty liver in adolescents and young adults: cross-sectional and prospective analyses of the BCAMS study
Adipokine/hepatokines profiling of fatty liver in adolescents and young adults: cross-sectional and prospective analyses of the BCAMS study
The underlying connections between obesity and non-alcoholic fatty liver disease (NAFLD) are not fully understood. One pot...
Appendicular skeletal muscle mass is associated with metabolic dysfunction-associated steatotic liver disease severity in young men: a cross-sectional and longitudinal study
Appendicular skeletal muscle mass is associated with metabolic dysfunction-associated steatotic liver disease severity in young men: a cross-sectional and longitudinal study
Although appendicular skeletal muscle mass (ASM) has been linked to the severity of hepatic steatosis, investigations of i...
Treatment of portal vein thrombosis in cirrhosis is associated with no survival advantage: a retrospective controlled study
Treatment of portal vein thrombosis in cirrhosis is associated with no survival advantage: a retrospective controlled study
Portal vein thrombosis (PVT) is associated with increased mortality post-transplant, but treatment of the clot is not defi...
Dynamic role of exosomal long non-coding RNA in liver diseases: pathogenesis and diagnostic aspects
Dynamic role of exosomal long non-coding RNA in liver diseases: pathogenesis and diagnostic aspects
Liver disease has emerged as a significant health concern, characterized by high rates of morbidity and mortality. Circula...
Is it necessary to distinguish between combined hepatocellular carcinoma-cholangiocarcinoma with less than 10% of cholangiocarcinoma components versus hepatocellular carcinoma?
Is it necessary to distinguish between combined hepatocellular carcinoma-cholangiocarcinoma with less than 10% of cholangiocarcinoma components versus hepatocellular carcinoma?
Whether there are differences in recurrence-free survival (RFS) prognosis between combined hepatocellular carcinoma-cholan...
Liver fibrosis is closely linked with metabolic-associated diseases in patients with autoimmune hepatitis
Liver fibrosis is closely linked with metabolic-associated diseases in patients with autoimmune hepatitis
This cross-sectional study aimed to investigate the impact of metabolic-associated diseases (MADs) on patients with autoim...
Diagnosis and management of pediatric acute liver failure: consensus recommendations of the Indian Society of Pediatric Gastroenterology, Hepatology, and Nutrition (ISPGHAN)
Diagnosis and management of pediatric acute liver failure: consensus recommendations of the Indian Society of Pediatric Gastroenterology, Hepatology, and Nutrition (ISPGHAN)
Timely diagnosis and management of pediatric acute liver failure (PALF) is of paramount importance to improve survival. Th...
Is laparoscopic hepatectomy superior to radiofrequency ablation in treating small hepatocellular carcinoma?
Is laparoscopic hepatectomy superior to radiofrequency ablation in treating small hepatocellular carcinoma?
National Natural Science Foundation of China, NSFC82073345, shuanghu yuan, Natural Science Innovation and Development Join...
Clinical features and mortality outcomes of patients with MASLD only compared to those with MAFLD and MASLD
Clinical features and mortality outcomes of patients with MASLD only compared to those with MAFLD and MASLD
The applicability of the proposed metabolic dysfunction-associated steatotic liver disease (MASLD) definition has not been...
Delicate and thin fibrous septa indicate a regression tendency in metabolic dysfunction-associated steatohepatitis patients with advanced fibrosis
Delicate and thin fibrous septa indicate a regression tendency in metabolic dysfunction-associated steatohepatitis patients with advanced fibrosis
Metabolic dysfunction-associated steatohepatitis (MASH)-related fibrosis is reversible. However, the dynamic morphology ch...
Acute presentation of autoimmune hepatitis –from acute hepatitis to ALF and ACLF-
Acute presentation of autoimmune hepatitis –from acute hepatitis to ALF and ACLF-
Acute presentation of autoimmune hepatitis (AIH) occurs in 22–43% of all AIH cases, and is not a rare condition. Rat...
The relationship between CXCR6+CD8+T cells and clinicopathological parameters in patients with primary biliary cholangitis
The relationship between CXCR6+CD8+T cells and clinicopathological parameters in patients with primary biliary cholangitis
CXCR6+CD8+T cells have been implicated in the pathogenesis of various liver and autoimmune diseases. However, their involv...
Mesenchymal stem cells-derived exosomes alleviate liver fibrosis by targeting Hedgehog/SMO signaling
Mesenchymal stem cells-derived exosomes alleviate liver fibrosis by targeting Hedgehog/SMO signaling
Despite increasing knowledge regarding the cellular and molecular mechanisms of liver fibrogenesis, there is currently no ...
Identification of PANoptosis-relevant subgroups and predicting signature to evaluate the prognosis and immune landscape of patients with biliary tract cancer
Identification of PANoptosis-relevant subgroups and predicting signature to evaluate the prognosis and immune landscape of patients with biliary tract cancer
This study conducted molecular subtyping of biliary tract cancer patients based on 19 PANoptosis-related gene signatures. ...
Acute-on-chronic liver failure in metabolic dysfunction-associated fatty liver disease patients: a disease multiplier
Acute-on-chronic liver failure in metabolic dysfunction-associated fatty liver disease patients: a disease multiplier
Acute-on-chronic liver failure (ACLF) is a syndrome of liver failure due to an acute hepatic insult leading to liver failu...
Liver and cardiovascular outcomes in lean non-alcoholic fatty liver disease: an updated systematic review and meta-analysis of about 1 million individuals
Liver and cardiovascular outcomes in lean non-alcoholic fatty liver disease: an updated systematic review and meta-analysis of about 1 million individuals
Non-alcoholic fatty liver disease (NAFLD) is present in lean people. However, the magnitude of the prognostic hepatic and ...
Dual-etiology MAFLD: the interactions between viral hepatitis B, viral hepatitis C, alcohol, and MAFLD
Dual-etiology MAFLD: the interactions between viral hepatitis B, viral hepatitis C, alcohol, and MAFLD
Metabolic dysfunction-associated fatty liver disease (MAFLD) and viral hepatitis due to chronic hepatitis B virus (HBV) or...
Metabolic dysfunction associated fatty liver disease in healthy weight individuals
Metabolic dysfunction associated fatty liver disease in healthy weight individuals
Metabolic dysfunction associated fatty liver disease (MAFLD) is an increasing public health problem, affecting one third o...
The impact of artificial liver support system on intestinal microbiota and serum bile acid profiles in patients with acute-on-chronic liver failure: a prospective cohort study
The impact of artificial liver support system on intestinal microbiota and serum bile acid profiles in patients with acute-on-chronic liver failure: a prospective cohort study
Acute-on-chronic liver failure (ACLF) patients exhibit an imbalance in intestinal microbiota, and bile acids (BAs) can aff...
Management and treatment of severe immune-related hepatotoxicity based on clinical and pathological characteristics
Management and treatment of severe immune-related hepatotoxicity based on clinical and pathological characteristics
The management of severe immune-related hepatotoxicity (irH) needs to be further optimized. This study aims to analyze the...
Role of gut microbiota and immune cells in metabolic-associated fatty liver disease: clinical impact
Role of gut microbiota and immune cells in metabolic-associated fatty liver disease: clinical impact
In 2020, a revised definition of fatty liver disease associated with metabolic dysfunction (MAFLD) was proposed to replace...
Treating extrahepatic portal-vein obstruction with cavernoma using radiological interventions: pushing the boundaries
Treating extrahepatic portal-vein obstruction with cavernoma using radiological interventions: pushing the boundaries
Intagliata NM, Caldwell SH, Tripodi A. Diagnosis, development, and treatment of portal vein thrombosis in patients with an...
Hepatic arterial infusion chemotherapy plus camrelizumab and apatinib for advanced hepatocellular carcinoma
Hepatic arterial infusion chemotherapy plus camrelizumab and apatinib for advanced hepatocellular carcinoma
There is limited information on combination of hepatic arterial infusion chemotherapy (HAIC) and systemic therapy for adva...
Clinical significance of circulating biomarkers of immune-checkpoint molecules with atezolizumab plus bevacizumab therapy in unresectable hepatocellular carcinoma
Clinical significance of circulating biomarkers of immune-checkpoint molecules with atezolizumab plus bevacizumab therapy in unresectable hepatocellular carcinoma
The aims of this study were to identify clinically significant biomarkers of a response to atezolizumab plus bevacizumab (...
Risk of hepatocellular carcinoma occurrence after antiviral therapy for patients with chronic hepatitis C Infection: a systematic review and meta-analysis
Risk of hepatocellular carcinoma occurrence after antiviral therapy for patients with chronic hepatitis C Infection: a systematic review and meta-analysis
The risk of hepatocellular carcinoma (HCC) occurrence following antiviral therapy in patients with chronic hepatitis C (CH...
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