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Prognostic significance of liver stiffness in patients with primary biliary cholangitis: validation of Baveno VII criteria
Prognostic significance of liver stiffness in patients with primary biliary cholangitis: validation of Baveno VII criteria
The role of liver stiffness measurements (LSM) in patients with primary biliary cholangitis (PBC) remains to be further el...
Prevalence and incidence of MAFLD and associated anthropometric parameters among prepubertal children of the Shanghai Birth Cohort
Prevalence and incidence of MAFLD and associated anthropometric parameters among prepubertal children of the Shanghai Birth Cohort
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common chronic liver disease in adolescent and ad...
The MAPS-CRAFITY score: a novel efficacy predictive tool for unresectable hepatocellular carcinoma treated with targeted therapy plus immunotherapy
The MAPS-CRAFITY score: a novel efficacy predictive tool for unresectable hepatocellular carcinoma treated with targeted therapy plus immunotherapy
Body composition parameters (BCPs) are associated with mortality in patients with hepatocellular carcinoma (HCC). Our purp...
ChIP-seq analysis found IL21R, a target gene of GTF2I–the susceptibility gene for primary biliary cholangitis in Chinese Han
ChIP-seq analysis found IL21R, a target gene of GTF2I–the susceptibility gene for primary biliary cholangitis in Chinese Han
Aimed to identify a new susceptibility gene associated with primary biliary cholangitis (PBC) in Chinese Han and investiga...
How does alcohol use impact morbidity and mortality of liver cirrhosis? A systematic review and dose–response meta-analysis
How does alcohol use impact morbidity and mortality of liver cirrhosis? A systematic review and dose–response meta-analysis
Alcohol consumption is the most important risk factor responsible for the disease burden of liver cirrhosis (LC). Estimate...
Propensity score matched analysis and risk stratification of donors with G6PD deficiency in living donor liver transplantation
Propensity score matched analysis and risk stratification of donors with G6PD deficiency in living donor liver transplantation
Glucose 6 phosphate dehydrogenase (G6PD) deficiency (G6PDd) can trigger hemolysis following surgical stress. Differentiati...
Development of a transformer model for predicting the prognosis of patients with hepatocellular carcinoma after radiofrequency ablation
Development of a transformer model for predicting the prognosis of patients with hepatocellular carcinoma after radiofrequency ablation
Radiofrequency ablation (RFA) is a widely accepted, minimally invasive treatment modality for patients with hepatocellular...
Impact of elobixibat on liver tumors, microbiome, and bile acid levels in a mouse model of nonalcoholic steatohepatitis
Impact of elobixibat on liver tumors, microbiome, and bile acid levels in a mouse model of nonalcoholic steatohepatitis
Elevated bile acid levels have been associated with liver tumors in fatty liver. Ileal bile acid transporter inhibitors ma...
Von Willebrand factor processing in patients with advanced chronic liver disease and its relation to portal hypertension and clinical outcome
Von Willebrand factor processing in patients with advanced chronic liver disease and its relation to portal hypertension and clinical outcome
Endothelial dysfunction and portal hypertension (PH) are reflected by increased von Willebrand factor antigen (VWF-Ag) lev...
Distinct on-treatment HCC risks associated with different decompensation events in HBV patients with cirrhosis
Distinct on-treatment HCC risks associated with different decompensation events in HBV patients with cirrhosis
Long-term treatment with nucleoside analog (NA) reduces the risks for decompensation and hepatocellular carcinoma (HCC) in...
Live donor liver transplantation for pediatric acute liver failure: challenges and outcomes
Live donor liver transplantation for pediatric acute liver failure: challenges and outcomes
This study aimed at studying the challenges and outcomes of live-donor liver transplantation (LDLT) for pediatric acute li...
Management of adults with Alagille syndrome
Management of adults with Alagille syndrome
Alagille syndrome (ALGS) is a complex rare genetic disorder that involves multiple organ systems and is historically regar...
Anti-PD-L1 antibodies promote cellular proliferation by activating the PD-L1–AXL signal relay in liver cancer cells
Anti-PD-L1 antibodies promote cellular proliferation by activating the PD-L1–AXL signal relay in liver cancer cells
Immune checkpoint inhibitors (ICIs) are emerging treatments for advanced hepatocellular carcinoma (HCC); however, evidence...
Current understanding and future perspectives on the impact of changing NAFLD to MAFLD on global epidemiology and clinical outcomes
Current understanding and future perspectives on the impact of changing NAFLD to MAFLD on global epidemiology and clinical outcomes
For the first time in nearly half a century, fatty liver disease has undergone a change in name and definition, from the e...
Mixed mode of artificial liver support in patients with acute-on-chronic liver failure: a retrospective cohort study
Mixed mode of artificial liver support in patients with acute-on-chronic liver failure: a retrospective cohort study
Different modes of artificial liver support (ALS) therapy can improve the survival of patients with acute-on-chronic liver...
Post-transplant inflammatory cytokine signature adds value for predicting tumor recurrence after liver transplantation for hepatocellular carcinoma
Post-transplant inflammatory cytokine signature adds value for predicting tumor recurrence after liver transplantation for hepatocellular carcinoma
Cytokines are key regulators of post-transplant inflammation responses which reconstitute post-transplant hepatic and syst...
3D automatic liver and spleen assessment in predicting overt hepatic encephalopathy before TIPS: a multi-center study
3D automatic liver and spleen assessment in predicting overt hepatic encephalopathy before TIPS: a multi-center study
Overt hepatic encephalopathy (HE) should be predicted preoperatively to identify suitable candidates for transjugular intr...
Asia–Pacific association for study of liver guidelines on management of ascites in liver disease
Asia–Pacific association for study of liver guidelines on management of ascites in liver disease
Eslam M, Sarin SK, Wong VWS, et al. The Asian Pacific Association for the Study of the Liver clinical practice guidelines ...
Long-term clinical outcomes of adults with metabolic dysfunction-associated fatty liver disease: a single-centre prospective cohort study with baseline liver biopsy
Long-term clinical outcomes of adults with metabolic dysfunction-associated fatty liver disease: a single-centre prospective cohort study with baseline liver biopsy
There are limited data on the long-term adverse clinical outcomes of adults with metabolic dysfunction-associated fatty li...
Lymphatic drainage dysfunction via narrowing of the lumen of cisterna chyli and thoracic duct after luminal dilation
Lymphatic drainage dysfunction via narrowing of the lumen of cisterna chyli and thoracic duct after luminal dilation
The chronological pattern of extrahepatic lymphatic vessel progression in the course of chronic liver disease has not been...
Alcohol-related hepatitis admissions decline in 2021 after a 2020 surge attributed to the COVID-19 pandemic
Alcohol-related hepatitis admissions decline in 2021 after a 2020 surge attributed to the COVID-19 pandemic
We previously investigated the impact of the COVID-19 pandemic on alcohol-related liver disease (ARLD), finding that admis...
Oxidative stress-related markers as prognostic factors for patients with primary sclerosing cholangitis in Japan
Oxidative stress-related markers as prognostic factors for patients with primary sclerosing cholangitis in Japan
Primary sclerosing cholangitis (PSC) is a rare chronic liver disease. The mechanisms and prediction of PSC progression are...
MEX3A determines in vivo hepatocellular carcinoma progression and induces resistance to sorafenib in a Hippo-dependent way
MEX3A determines in vivo hepatocellular carcinoma progression and induces resistance to sorafenib in a Hippo-dependent way
Hepatocellular carcinoma (HCC) is most common malignant tumor worldwide, and one of the most lethal malignancies. MEX3A, R...
Prospects for treatment of esophageal varices considering the safety of endoscopic band ligation
Prospects for treatment of esophageal varices considering the safety of endoscopic band ligation
In a large cohort validation, Pfisterer et al. evaluated the incidence of PRB within 30 days after EBL. They found that on...
Perioperative safety, oncologic outcome, and risk factors of salvage liver resection for initially unresectable hepatocellular carcinoma converted by transarterial chemoembolization plus tyrosine kinase inhibitor and anti-PD-1 antibody: a retrospective multicenter study of 83 patients
Perioperative safety, oncologic outcome, and risk factors of salvage liver resection for initially unresectable hepatocellular carcinoma converted by transarterial chemoembolization plus tyrosine kinase inhibitor and anti-PD-1 antibody: a retrospective multicenter study of 83 patients
To assess the perioperative safety, oncological outcomes, and determinants influencing the oncological outcomes of salvage...
Targeting immuno-metabolism and anti-viral immune responses in chronic hepatitis B
Targeting immuno-metabolism and anti-viral immune responses in chronic hepatitis B
Chronic hepatitis B (CHB), caused by the hepatitis B virus (HBV), is a worldwide burd...
Consensus on the tertiary prevention of primary liver cancer
Consensus on the tertiary prevention of primary liver cancer
To effectively prevent recurrence, improve the prognosis and increase the survival rate of primary liver cancer (PLC) pati...
Hepatitis B virus-related intrahepatic cholangiocarcinoma originates from hepatocytes
Hepatitis B virus-related intrahepatic cholangiocarcinoma originates from hepatocytes
Hepatitis B virus (HBV) infection is one of the most common risk factors for intrahepatic cholangiocarcinoma (ICC). Howeve...
Liver fibrosis quantified by image morphometry predicts clinical outcomes in patients with non-alcoholic fatty liver disease
Liver fibrosis quantified by image morphometry predicts clinical outcomes in patients with non-alcoholic fatty liver disease
Liver fibrosis predicts adverse clinical outcomes, such as liver-related death (LRD) and hepatocellular carcinoma (HCC) in...
Clathrin light chain A facilitates small extracellular vesicle uptake to promote hepatocellular carcinoma progression
Clathrin light chain A facilitates small extracellular vesicle uptake to promote hepatocellular carcinoma progression
Endocytosis is a fundamental process for internalizing small extracellular vesicles (sEVs). The present study aimed to elu...
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