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Insights into the molecular underlying mechanisms and therapeutic potential of endoplasmic reticulum stress in sensorineural hearing loss
Insights into the molecular underlying mechanisms and therapeutic potential of endoplasmic reticulum stress in sensorineural hearing loss
1 Introduction Sensorineural hearing loss (SNHL) is one of the most common types of hearing loss (HL), which affects soci...
Retraction: Endothelial-monocyte activating polypeptide II suppresses the in vitro glioblastoma-induced angiogenesis by inducing autophagy
The publisher retracts the article cited above.Following publication, concerns were raised regarding the integrity of the ...
Circulating miR-134 in mesial temporal lobe epilepsy: implications in hippocampal sclerosis development and drug resistance
1 Introduction Epilepsy is a chronic neurological disease that affects more than 50 million persons worldwide, 80% of wh...
Sensory innervation in the prostate and a role for calcitonin gene-related peptide in prostatic epithelial proliferation
Introduction The prostate is a male accessory sex organ that plays a key role in reproductive function by maintaining sp...
VNS paired with training enhances recognition memory: mechanistic insights from proteomic analysis of the hippocampal synapse
1 Introduction Recognition memory is a fundamental component of cognitive health, allowing us to learn and remember new ...
A sex-specific effect of M4 muscarinic cholinergic autoreceptor deletion on locomotor stimulation by cocaine and scopolamine
1 Introduction Acetylcholine regulates numerous critical functions within the basal ganglia by activating nicotinic and m...
Chaperones vs. oxidative stress in the pathobiology of ischemic stroke
1 Introduction The global burden inflicted by ischemic stroke is dramatic: the annual number of new cases [7,630,803 in 2...
Excitatory neuron-prone prion propagation and excitatory neuronal loss in prion-infected mice
Introduction Prion diseases are fatal and intractable neurodegenerative disorders affecting both animals and humans, inc...
Calcium-sensor proteins but not bicarbonate ion activate retinal photoreceptor membrane guanylyl cyclase in photoreceptors
Introduction Vertebrate rods and cones respond to light by changing the permeability of cyclic nucleotide-gated cation c...
Development of KCC2 therapeutics to treat neurological disorders
Introduction The KCC2 transporter is the CNS neuron-specific Cl– extruder essential for the establishment and maintenance...
Mitochondrial pathways of copper neurotoxicity: focus on mitochondrial dynamics and mitophagy
1 Introduction Copper (Cu) is an essential element involved in a plethora of metabolic processes through its structural,...
Transcorneal electrical stimulation restores DNA methylation changes in retinal degeneration
Introduction Retinal degeneration is a major cause of irreversible blindness. It is projected that the incidence of reti...
Corrigendum: Mechanisms of mitophagy and oxidative stress in cerebral ischemia–reperfusion, vascular dementia, and Alzheimer's disease
• please read through all the templates before choosing• pick the most relevant text template(s) from the following page a...
Differential timing of mitochondrial activation in rat dorsal striatum induced by procedural learning and swimming
1 Introduction Aversive learning experiences are associated with the activation of the hypothalamic-pituitary-adrenal axi...
Cell-autonomous action of Slit2 in radial migration of cortical projection neurons
Introduction The cerebral cortex is a highly ordered brain structure with neurons organized into six distinct layers. Th...
TMAO is involved in sleep deprivation-induced cognitive dysfunction through regulating astrocytic cholesterol metabolism via SREBP2
1 Introduction Sleep loss appears common daily and has become a global public health issue. According to the World Healt...
Optogenetic elevation of postsynaptic cGMP in the hippocampal dentate gyrus enhances LTP and modifies mouse behaviors
Optogenetic elevation of postsynaptic cGMP in the hippocampal dentate gyrus enhances LTP and modifies mouse behaviors
Introduction The intracellular messengers, cyclic AMP (cAMP) and cyclic GMP (cGMP), are involved in the mechanisms of sy...
Toll-like receptors as a missing link in Notch signaling cascade during neurodevelopment
1 Notch and Toll—structural and signaling features During neurodevelopment, neural progenitor cells (NPCs) settled in th...
Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevoflurane
1 Introduction Sevoflurane is an anesthetic widely used in pediatric general anesthesia, whether it is safe to applicati...
Perinuclear compartment controls calcineurin/MEF2 signaling for axonal outgrowth of hippocampal neurons
1 Introduction A unique and fundamental characteristic of the nervous system during development is the ability of neuron...
Editorial: Antiviral drugs: neurotoxicity and neurodevelopmental effects
Several anti-viral drugs like those used to treat human immunodeficiency virus (HIV) infections have been associated with ...
Peptide discovery across the spectrum of neuroinflammation; microglia and astrocyte phenotypical targeting, mediation, and mechanistic understanding
1 Introduction Neuroinflammation, inflammation centering in the central nervous system (CNS), is the core biological feat...
Metabolomic profile of cerebral tissue after acoustically-mediated blood-brain barrier opening in a healthy rat model: a focus on the contralateral side
1 Introduction Microbubble-assisted ultrasound (MB-assisted US) is a promising modality for the efficient, safe, and tar...
Inhibition of midbrain cholinergic neurons impairs decision-making strategies during reversal learning
Introduction Behavioral flexibility refers to the ability to adjust behavior in response to contingency changes in the e...
Editorial: Regulators of synapse formation: understanding the molecular mechanisms and its dysregulation in neurodevelopmental disorders
and behavioral functions. This research topic comprises six articles that explore the latest discoveries in the molecular ...
Increased nuclear import characterizes aberrant nucleocytoplasmic transport in neurons from patients with spinocerebellar ataxia type 7
1 Introduction Spinocerebellar ataxia type 7 (SCA7) is a hereditary autosomal dominant neurodegenerative disorder charac...
The good, the bad, and the unknown nature of decreased GD3 synthase expression
1 Introduction Gangliosides, complex glycosphingolipids, challenging to investigate with common molecular biology method...
Regulation of adult neurogenesis: the crucial role of astrocytic mitochondria
1 Introduction Early childhood experiences, particularly sensory stimulation, are critical for brain development and are...
Effects of chronodisruption and alcohol consumption on gene expression in reward-related brain areas in female rats
Introduction Alcohol use disorder is a global public health concern, contributing to millions of premature deaths each y...
Reported race-associated differences in control and schizophrenia post-mortem brain transcriptomes implicate stress-related and neuroimmune pathways
Introduction Schizophrenia (SCZ) is a severe mental disorder affecting 1% of the world’s population, characterized by de...
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