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Introduction to immunology and immune disorders
Introduction to immunology and immune disorders
The body has a collection of physical barriers to prevent infection, but once these are overcome, we rely on our immune sy...
The efficacy and safety of stepwise oral food challenge in children with hen’s egg allergy
The efficacy and safety of stepwise oral food challenge in children with hen’s egg allergy
Oral food challenge (OFC) is the gold standard for diagnosing food allergies (FAs) but carries the risk of anaphylactic re...
Non-immunoglobulin E-mediated food allergy
Non-immunoglobulin E-mediated food allergy
Non-immunoglobulin E (IgE)-mediated food allergies are characterized by delayed gastrointestinal (GI) manifestations that ...
Primary prevention of food allergy: beyond early introduction
Primary prevention of food allergy: beyond early introduction
Food allergy typically begins early in life and persists as a lifelong condition. Delayed introduction of allergenic foods...
Angioedema
Angioedema
Angioedema can occur in the absence of urticaria and can be broadly divided into three main categories: mast cell-mediated...
Canadian Society of Allergy and Clinical Immunology position statement: panel testing for food allergies
Canadian Society of Allergy and Clinical Immunology position statement: panel testing for food allergies
This position statement addresses the critical concerns and recommended practices surrounding the use of panel food testin...
Efficacy of probiotics as adjuvant therapy in bronchial asthma: a systematic review and meta-analysis
Efficacy of probiotics as adjuvant therapy in bronchial asthma: a systematic review and meta-analysis
Asthma is a chronic, heterogeneous disease characterized by airway inflammation. Asthma exacerbations significantly increa...
Zéro allergie research clinic: a clinical and research initiative in oral immunotherapy for managing IgE-mediated food allergy
Zéro allergie research clinic: a clinical and research initiative in oral immunotherapy for managing IgE-mediated food allergy
The Zéro allergie research clinic (Saguenay, Canada) is a clinical and research initiative in oral immunotherapy (OIT...
Safety and adherence of early oral immunotherapy for peanut allergy in a primary care setting: a retrospective cross-sectional study
Safety and adherence of early oral immunotherapy for peanut allergy in a primary care setting: a retrospective cross-sectional study
Peanut allergy is a common food allergy with potentially life-threatening implications. Early oral immunotherapy for peanu...
Eosinophil count testing in patients with asthma varies by healthcare provider type in the US: a retrospective study
Eosinophil count testing in patients with asthma varies by healthcare provider type in the US: a retrospective study
Patients with asthma with an eosinophilic phenotype may be eligible for additional treatment options to improve disease co...
A case report of fatal anaphylaxis on first exposure to rasburicase just before lymphoma treatment
A case report of fatal anaphylaxis on first exposure to rasburicase just before lymphoma treatment
Rasburicase, a recombinant urate oxidase enzyme, has potent efficacy in controlling uric acid and is widely used to preven...
Real-world experience: a retrospective pediatric chart review to determine why patients and caregivers discontinue oral immunotherapy
Real-world experience: a retrospective pediatric chart review to determine why patients and caregivers discontinue oral immunotherapy
Oral immunotherapy (OIT) is an increasingly utilized management strategy for IgE-mediated food allergy. Despite promising ...
Oral immunotherapy improves the quality of life of adults with food allergy
Oral immunotherapy improves the quality of life of adults with food allergy
Oral immunotherapy (OIT) has become the standard of care for children with food allergy (FA) and has substantially improve...
Infusion parameters, safety, and practical guidance for the manual administration of subcutaneous immunoglobulin 20% (Ig20Gly)
Infusion parameters, safety, and practical guidance for the manual administration of subcutaneous immunoglobulin 20% (Ig20Gly)
Primary immunodeficiency diseases (PIDs), also referred to as inborn errors of immunity, constitute a group of genetic con...
Osthole attenuates asthma-induced airway epithelial cell apoptosis and inflammation by suppressing TSLP/NF-κB-mediated inhibition of Th2 differentiation
Osthole attenuates asthma-induced airway epithelial cell apoptosis and inflammation by suppressing TSLP/NF-κB-mediated inhibition of Th2 differentiation
The aim of this study was to investigate the influence of osthole (OS) on asthma-induced airway epithelial cell apoptosis ...
Real-world outcomes of patients with hereditary angioedema with normal C1-inhibitor function and patients with idiopathic angioedema of unknown etiology in Canada
Real-world outcomes of patients with hereditary angioedema with normal C1-inhibitor function and patients with idiopathic angioedema of unknown etiology in Canada
Hereditary angioedema with normal C1-inhibitor function (HAE nC1-INH) and idiopathic angioedema of unknown etiology (AE-UN...
Severe exacerbation of facial dermatitis with swelling following introduction of abrocitinib in a patient with atopic dermatitis
Severe exacerbation of facial dermatitis with swelling following introduction of abrocitinib in a patient with atopic dermatitis
Abrocitinib, an oral small-molecule Janus kinase 1 (JAK1) inhibitor, has been widely accepted for the treatment of moderat...
fSCIG 10% in pediatric primary immunodeficiency diseases: a European post-authorization safety study
fSCIG 10% in pediatric primary immunodeficiency diseases: a European post-authorization safety study
The safety, tolerability, and immunogenicity of hyaluronidase-facilitated subcutaneous immunoglobulin (fSCIG) 10% (dual-vi...
Exploratory pharmacodynamics and efficacy of PF-06817024 in a Phase 1 study of patients with chronic rhinosinusitis and atopic dermatitis
Exploratory pharmacodynamics and efficacy of PF-06817024 in a Phase 1 study of patients with chronic rhinosinusitis and atopic dermatitis
PF-06817024 is a humanized antibody against interleukin-33 that has the potential to inhibit type 2 inflammation. An explo...
Focused allergic rhinitis practice parameter for Canada
Focused allergic rhinitis practice parameter for Canada
Allergic rhinitis (AR) is a prevalent disease in Canada that affects both children and adults. Several guidelines for the ...
The complexities of decision-making associated with on-demand treatment of hereditary angioedema (HAE) attacks
The complexities of decision-making associated with on-demand treatment of hereditary angioedema (HAE) attacks
Hereditary angioedema (HAE) is characterized by debilitating attacks of tissue swelling in various locations. While guidel...
Role of Th2, Th17 and Treg Cells and relevant cytokines in pathogenesis of allergic rhinitis
Role of Th2, Th17 and Treg Cells and relevant cytokines in pathogenesis of allergic rhinitis
To explore the role of different cells and molecules in the pathogenesis of allergic rhinitis (AR) with positive Artemisia...
Severe distributive shock, neutrophilic dermatosis, and ST-elevation myocardial infarction in the setting of azathioprine hypersensitivity syndrome
Severe distributive shock, neutrophilic dermatosis, and ST-elevation myocardial infarction in the setting of azathioprine hypersensitivity syndrome
Azathioprine is a purine synthesis inhibitor used as an immunosuppressive therapy for many immune-mediated diseases. Azath...
Knockdown of miR-155 alleviates skin damage in rats with chronic spontaneous urticaria by modulating the JAK/STAT signaling pathway
Knockdown of miR-155 alleviates skin damage in rats with chronic spontaneous urticaria by modulating the JAK/STAT signaling pathway
The aim of this study was to investigate the role and mechanisms of miR-155 in chronic spontaneous urticaria (CSU). The ex...
A real-world evaluation of the effectiveness and Sufficiency of Current Emergency Department Preventative Strategies for Reducing Emergency Department revisits in a Canadian children’s hospital: a retrospective cohort study
A real-world evaluation of the effectiveness and Sufficiency of Current Emergency Department Preventative Strategies for Reducing Emergency Department revisits in a Canadian children’s hospital: a retrospective cohort study
Despite asthma guidelines’ recommended emergency department preventative strategies (EDPS), repeat asthma-related em...
Therapeutic potential of the topical recombinant human interleukin-1 receptor antagonist in guinea pigs with allergic rhinitis
Therapeutic potential of the topical recombinant human interleukin-1 receptor antagonist in guinea pigs with allergic rhinitis
Recombinant human Interleukin receptor antagonist (rhIL-Ra) can bind to the IL-1 receptor on the cell membrane and reversi...
Anaphylaxis in a Swiss university emergency department: clinical characteristics and supposed triggers
Anaphylaxis in a Swiss university emergency department: clinical characteristics and supposed triggers
Anaphylaxis is the most severe form of acute systemic and potentially life-threatening reactions triggered by mast and bas...
Comparison of cytokine expression and disease severity between plasma cell-dominant and eosinophil-dominant patients in chronic rhinosinusitis with nasal polyps
Comparison of cytokine expression and disease severity between plasma cell-dominant and eosinophil-dominant patients in chronic rhinosinusitis with nasal polyps
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous disease characterized by inflammation of the nasal an...
Sublingual immunotherapy for allergy to shrimp: the nine-year clinical experience of a Midwest Allergy-Immunology practice
Sublingual immunotherapy for allergy to shrimp: the nine-year clinical experience of a Midwest Allergy-Immunology practice
Diet restrictions and fear of adverse reactions put a significant burden on the nutrition, growth and life style of childr...
Genetic links between atopy, allergy, and alopecia areata: insights from a Mendelian randomization study
Genetic links between atopy, allergy, and alopecia areata: insights from a Mendelian randomization study
Alopecia areata (AA), a prevalent form of autoimmune hair loss, has a not well-defined relationship with atopic and allerg...
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