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Potential Risk Factors of Drug-Related Problems in Hospital-Based Mental Health Units: A Systematic Review
Potential Risk Factors of Drug-Related Problems in Hospital-Based Mental Health Units: A Systematic Review
Reducing the occurrence of drug-related problems is a global health concern. In mental health hospitals, drug-related prob...
Fully Liquid MenACWY-CRM Vaccine: Results from an Integrated Safety Analysis
Fully Liquid MenACWY-CRM Vaccine: Results from an Integrated Safety Analysis
The currently licensed quadrivalent MenACWY-CRM conjugate vaccine presentation consists of two vials (lyophilized MenA and...
Optimizing Safety Surveillance for COVID-19 Vaccines at the National Pharmacovigilance Centre Lareb: One Year of COVID-19 Vaccine Experience
Optimizing Safety Surveillance for COVID-19 Vaccines at the National Pharmacovigilance Centre Lareb: One Year of COVID-19 Vaccine Experience
Due to the COVID-19 vaccination campaign, national pharmacovigilance (PV) centres had to deal with high volumes of Individ...
Topiramate Utilization After Phentermine/Topiramate Approval for Obesity Management: Risk Minimization in the Era of Drug Repurposing
Topiramate Utilization After Phentermine/Topiramate Approval for Obesity Management: Risk Minimization in the Era of Drug Repurposing
The US FDA required a Risk Evaluation and Mitigation Strategy (REMS) for phentermine/topiramate, an anti-obesity medicatio...
Characterization of Serous Retinopathy Associated with Cobimetinib: Integrated Safety Analysis of Four Studies
Characterization of Serous Retinopathy Associated with Cobimetinib: Integrated Safety Analysis of Four Studies
Serous retinopathy can be associated with MEK inhibitors, including cobimetinib. We present results of an integrated safet...
A Population-Based Study of SGLT2 Inhibitor-Associated Postoperative Diabetic Ketoacidosis in Patients with Type 2 Diabetes
A Population-Based Study of SGLT2 Inhibitor-Associated Postoperative Diabetic Ketoacidosis in Patients with Type 2 Diabetes
Operations are a major precipitating factor for sodium-glucose co-transporter 2 inhibitor (SGLT2i)-associated diabetic ket...
Comparison of the MOdified NARanjo Causality Scale (MONARCSi) for Individual Case Safety Reports vs. a Reference Standard
Comparison of the MOdified NARanjo Causality Scale (MONARCSi) for Individual Case Safety Reports vs. a Reference Standard
In 2018, we published the MONARCSi algorithmic decision support tool showing high inter-rater agreement, moderate sensitiv...
Gastrointestinal Bleeding on Oral Anticoagulation: What is Currently Known
Gastrointestinal Bleeding on Oral Anticoagulation: What is Currently Known
Gastrointestinal bleeding (GIB) is the most common type of bleeding occurring in patients on oral anticoagulation. A meta-...
Prevalence, Causes and Severity of Medication Administration Errors in the Neonatal Intensive Care Unit: A Systematic Review and Meta-Analysis
Prevalence, Causes and Severity of Medication Administration Errors in the Neonatal Intensive Care Unit: A Systematic Review and Meta-Analysis
Neonates are at greater risk of preventable adverse drug events as compared to children and adults. This study aimed to es...
Safety of Apremilast in Patients with Psoriasis and Psoriatic Arthritis: Findings from the UK Clinical Practice Research Datalink
Safety of Apremilast in Patients with Psoriasis and Psoriatic Arthritis: Findings from the UK Clinical Practice Research Datalink
This real-world safety analysis was requested by the European Medicines Agency following approval of apremilast, an oral t...
Lost in Translation: A Multilingual Survey of Interlinguistic Variations in Terms Used in Pharmacovigilance
Lost in Translation: A Multilingual Survey of Interlinguistic Variations in Terms Used in Pharmacovigilance
Although English is the universal language of science, it is nevertheless the first language of only about 6% of the world...
Pediatric Drug Safety Surveillance: A 10-Year Analysis of Adverse Drug Reaction Reporting Data in Calabria, Southern Italy
Pediatric Drug Safety Surveillance: A 10-Year Analysis of Adverse Drug Reaction Reporting Data in Calabria, Southern Italy
The paucity of pediatric clinical trials has led to many medicines frequently prescribed to children without a license for...
High-Dose Intravenous Iron with Either Ferric Carboxymaltose or Ferric Derisomaltose: A Benefit-Risk Assessment
High-Dose Intravenous Iron with Either Ferric Carboxymaltose or Ferric Derisomaltose: A Benefit-Risk Assessment
The intravenous iron formulations ferric carboxymaltose (FCM) and ferric derisomaltose (FDI) offer the possibility of admi...
Therapeutic Management of Idiosyncratic Drug-Induced Liver Injury and Acetaminophen Hepatotoxicity in the Paediatric Population: A Systematic Review
Therapeutic Management of Idiosyncratic Drug-Induced Liver Injury and Acetaminophen Hepatotoxicity in the Paediatric Population: A Systematic Review
Drug-induced liver injury (DILI) is a rare but serious adverse event that can progress to acute liver failure (ALF). The e...
Conundrum of Clinical QTc Monitoring
Conundrum of Clinical QTc Monitoring
Fenichel RR, Malik M, Antzelevitch C, Sanguinetti M, Roden DM, Priori SG, Ruskin JN, Lipicky RJ, Cantilena LR. Drug-induce...