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Tearing CRISPR apart
Tearing CRISPR apart
This study shows that the anti-CRISPR protein AcrIF25 inhibits the type I-F CRISPR–Cas system by pulling apart the f...
The indoors microbiome and human health
The indoors microbiome and human health
Indoor environments serve as habitat for humans and are replete with various reservoirs and niches for microorganisms. Mic...
Getting wound closure with Alcaligenes
Getting wound closure with Alcaligenes
In this study, White et al. report that Alcaligenes faecalis mediates wound repair in diabetic foot ulcers.
The interplay between diet and the gut microbiome: implications for health and disease
The interplay between diet and the gut microbiome: implications for health and disease
Diet has a pivotal role in shaping the composition, function and diversity of the gut microbiome, with various diets havin...
Indirect intervention
This study shows that accounting for spillover effects increased the cost-effectiveness of combined malaria-elimination in...
Cross-kingdom nutrient exchange in the plant–arbuscular mycorrhizal fungus–bacterium continuum
Cross-kingdom nutrient exchange in the plant–arbuscular mycorrhizal fungus–bacterium continuum
The association between plants and arbuscular mycorrhizal fungi (AMF) affects plant performance and ecosystem functioning....
Malaria vaccines: a new era of prevention and control
Malaria vaccines: a new era of prevention and control
Malaria killed over 600,000 people in 2022, a death toll that has not improved since 2015. Additionally, parasites and mos...
Busting Cryptococcus with brilacidin
In this study, Diehl et al. report that brilacidin could be a promising antifungal drug against Cryptococcus neoformans.
The pathobiology of human fungal infections
The pathobiology of human fungal infections
Human fungal infections are a historically neglected area of disease research, yet they cause more than 1.5 million deaths...
Bacterial barcoding facilitates plant microbiome studies
Bacterial barcoding facilitates plant microbiome studies
This month’s Genome Watch highlights the use of genetic barcoding towards a better understanding of plant–micr...
Bacteria curb emissions in farmland
Bacteria curb emissions in farmland
In this study, Hiis et al. demonstrate that the N2O-respiring bacterial strain Cloacibacterium sp. CB-01 can reduce nitrou...
Pertussis vaccines, epidemiology and evolution
Pertussis vaccines, epidemiology and evolution
Pertussis, which is caused by Bordetella pertussis, has plagued humans for at least 800 years, is highly infectious ...
Gassy archaea
This study shows that archaea produce catalytically active ultraminimal as well as hybrid [FeFe] hydrogenases.
Enterococcus faecium: evolution, adaptation, pathogenesis and emerging therapeutics
Enterococcus faecium: evolution, adaptation, pathogenesis and emerging therapeutics
The opportunistic pathogen Enterococcus faecium colonizes humans and a wide range of animals, endures numerous stresses, r...
A virus hastens ageing in flies
In this study, Niggs et al. show that Drosophila A virus infection modulates epithelial turnover in the intestine of Droso...
Supra-structures to target lipid II
Supra-structures to target lipid II
This study reports that plectasin uses a supramolecular antimicrobial mode of action, whereby the oligomerized peptide seq...
ESKAPE pathogens: antimicrobial resistance, epidemiology, clinical impact and therapeutics
ESKAPE pathogens: antimicrobial resistance, epidemiology, clinical impact and therapeutics
The rise of antibiotic resistance and a dwindling antimicrobial pipeline have been recognized as emerging threats to publi...
Co‐evolution of early Earth environments and microbial life
Co‐evolution of early Earth environments and microbial life
Two records of Earth history capture the evolution of life and its co-evolving ecosystems with interpretable fidelity: the...
Foodborne bacterial pathogens: genome-based approaches for enduring and emerging threats in a complex and changing world
Foodborne bacterial pathogens: genome-based approaches for enduring and emerging threats in a complex and changing world
Foodborne illnesses pose a substantial health and economic burden, presenting challenges in prevention due to the diverse ...
The gut–airway microbiome axis in health and respiratory diseases
The gut–airway microbiome axis in health and respiratory diseases
Communication between the gut and remote organs, such as the brain or the cardiovascular system, has been well established...
Fat, Desulfovibrio and cancer
This study by Chen et al. reveals that a high-fat diet leads to a predominance of Desulfovibrio species in the gut, correl...
Discovering molecular paradigms of microbial carcinogenesis
In this Journal Club, Carrie Shaffer discusses a study revealing that infection with CagA-positive Helicobacter pylori str...
Breaking through the concept barrier to develop broad-spectrum antiviral counter-measures
In this Journal Club, Yi Shi discusses a paper reporting that influenza virus infection in humans induces broadly cross-re...
Defending against plasmids
This study reports the mechanism of plasmid clearance by the DNA defence module DdmDE of the Vibrio cholerae seventh pande...
Tracking pathogen evolution through climate change
Tracking pathogen evolution through climate change
This Genome Watch article discusses the application of sequencing methods for monitoring the rise of infectious diseases a...
Viruses on the move
Viruses on the move
This study shows how two umbravirus-like viruses induce systemic infection in the plant host in the absence of virus-encod...
A mosquito symbiont controls flaviviruses
A mosquito symbiont controls flaviviruses
In this study, Zhang et al. report that a bacterial symbiont residing in the gut of Aedes albopictus mosquitoes protects t...
Bacteriocin diversity, function, discovery and application as antimicrobials
Bacteriocin diversity, function, discovery and application as antimicrobials
Bacteriocins are potent antimicrobial peptides that are produced by bacteria. Since their discovery almost a century ago, ...
Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance
Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance
The ecological and evolutionary mechanisms of antimicrobial resistance (AMR) emergence within patients and how these vary ...
Mycetocola to the rescue
In this study, Carrasco Flores et al. report that the bacterium Mycetocola lacteus protects the microalga Chlamydomonas re...