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Responding to extreme climates
A recent study found that soil microbial communities show consistent and predictable responses to extreme climatic events.
Commensals find their niche
A recent study shows that the commensal bacterium Lactiplantibacillus plantarum recognizes the foregut of the fruit fly as...
Author Correction: Examining the healthy human microbiome concept
APC Microbiome Ireland, University College Cork, Cork, IrelandRaphaela Joos, Katy Boucher, Aonghus Lavelle, Marcus J. Clae...
Gut phages fuel food addiction
Gut phages fuel food addiction
In this study, Castells-Nobau et al. show that bacteriophages present in the gut microbiome contribute to the regulation o...
Linking innate immune evasion to pandemic potential
In this journal club, Lucy Thorne discusses a paper that compares pandemic and non-pandemic HIV and shows that the ability...
Campylobacter spreads colorectal cancer
Campylobacter spreads colorectal cancer
This study shows that the Campylobacter jejuni-derived genotoxin named cytolethal distending toxin promotes colorectal can...
Metagenomics for drug discovery
In this study, Padhi et al. demonstrate the potential of metagenomics-based approaches for the discovery of natural produc...
Methanogens implicated by DNA evidence
Methanogens implicated by DNA evidence
This Genome Watch article highlights recent findings that expand the known diversity of methanogenic archaea and the metag...
Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions
Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions
Shigella sonnei is a major cause of diarrhoea globally and is increasing in prevalence relative to other Shigella because ...
The consequences of SARS-CoV-2 within-host persistence
The consequences of SARS-CoV-2 within-host persistence
SARS-CoV-2 causes an acute respiratory tract infection that resolves in most people in less than a month. Yet some people ...
Antibiotic-recalcitrant Salmonella during infection
Antibiotic-recalcitrant Salmonella during infection
Antibiotic-recalcitrant infections, defined as the prolonged carriage of pathogenic bacteria even in the presence of antib...
Predicting phage–host specificity
In a recent study, Gaborieau, Vaysset, Tesson et al. developed a method to predict phage–host specificity using geno...
Designer viral receptors
In a recent study, Liu, Huang, Guo, McCallum et al. present a method to create functional, customized coronavirus receptor...
Iron gatekeeper in malaria
Loveridge and Sigala uncover a divalent metal transporter that is required for cellular iron metabolism in Plasmodium falc...
Hepatitis B and D virus entry
Hepatitis B and D virus entry
Hepatitis B virus (HBV) entry is the initial step of viral infection, leading to the formation of covalently closed circul...
Gut microbiota clocks in stress
Gut microbiota clocks in stress
In this study, Tofani et al. demonstrate that the gut microbiota regulates stress responsiveness in mice via the circadian...
Waning resistance
This study provides insights into how adaptive changes in evolved microbial communities can affect pathogen invasion.
A mimic targets intracellular Staphylococcus aureus
In this study, Ge et al. develop a mimic of natural killer cells to target and eliminate intracellular Staphylococcus aureus.
A river of resistant genes uncovered by metagenomics
A river of resistant genes uncovered by metagenomics
This Genome Watch discusses the use of metagenomic sequencing to investigate resistome dynamics in river ecosystems and th...
Gender justice and prioritizing women and girls in the HIV response
A strategic dialogue on ‘gender justice in the HIV response’ held at the 25th International AIDS Conference hi...
The microbial phosphorus cycle in aquatic ecosystems
The microbial phosphorus cycle in aquatic ecosystems
Phosphorus is an essential element for life, and phosphorus cycling is crucial to planetary habitability. In aquatic envir...
In tandem towards resistance
In tandem towards resistance
This study shows that high-level resistance in methicillin-resistant Staphylococcus aureus involves an alternative mode of...
Streptococcus pneumoniae epidemiology, pathogenesis and control
Streptococcus pneumoniae epidemiology, pathogenesis and control
Infections caused by Streptococcus pneumoniae (also known as pneumococci) pose a threat to human health. Pneumococcal infe...
Microbiome-colonizing RNAs
This study describes the discovery of a previously uncharacterized phylogenetically distinct group of viroid-like human mi...
Anti-defence islands in plasmids
Anti-defence islands in plasmids
This new study shows that the leading region of plasmids has a key role in overcoming host immunity by functioning as R...
Examining the healthy human microbiome concept
Examining the healthy human microbiome concept
Human microbiomes are essential to health throughout the lifespan and are increasingly recognized and studied for their ro...
Harnessing symbiotic bacteria for disease control
Harnessing symbiotic bacteria for disease control
This Genome Watch explores recent transcriptomic and metatranscriptomic analyses that revealed the key role of secondary e...
Diversity and ecology of microbial sulfur metabolism
Diversity and ecology of microbial sulfur metabolism
Sulfur plays a pivotal role in interactions within the atmosphere, lithosphere, pedosphere, hydrosphere and biosphere, and...
Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention
Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention
Bloodstream infections (BSIs) are common in hospitals, often life-threatening and increasing in prevalence. Microorganisms...
A gut bacterium trims mucosal immunity
A gut bacterium trims mucosal immunity
In this study, Lu et al. identify the gut symbiont Tomasiella immunophila as a contributor to the degradation of murine se...