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Mining microbiomes for microproteins
Mining microbiomes for microproteins
This Genome Watch discusses strategies to detect small open reading frames and study microproteins encoded in microbiomes ...
Overcoming research challenges in resource-limited settings: perspectives from Thailand
This Comment highlights the challenges and rewards of researchers working in resource-limited settings, specifically Thail...
Bacterial contact killing
This study reports that bacteria protect plants against filamentous fungal infections via intercellular contacts between t...
A kill switch for tuberculosis
A kill switch for tuberculosis
In two recent studies, Smith, Su, Wallach et al. engineered a safer version of Bacille Calmette–Guerin with strong p...
Stopping Marburg virus in its tracks
In this study, Cross, Woolsey, Prasad et al. report obeldesivir as a promising post-exposure prophylaxis for filoviruses.
Opposing forces
Opposing forces
This study shows that metabolites from both an infecting pathogen and the gut microbiota of the host are major determinant...
Microbial interactions lead to ecosystem function
In this Journal Club, Flora Vincent revisits a paper that summarized the ecological roles of microorganisms in the ocean e...
Norovirus replication, host interactions and vaccine advances
Norovirus replication, host interactions and vaccine advances
Human noroviruses (HuNoVs) are the leading cause of acute gastroenteritis worldwide in all age groups and cause significan...
Microbial secondary metabolites: advancements to accelerate discovery towards application
Microbial secondary metabolites: advancements to accelerate discovery towards application
Microbial secondary metabolites not only have key roles in microbial processes and relationships but are also valued in va...
Microbiota–neuroepithelial signalling across the gut–brain axis
Microbiota–neuroepithelial signalling across the gut–brain axis
Research over the past two decades has established a remarkable ability of the gut microbiota to modulate brain activity a...
Taking the jump to humans
In a recent study, Lin et al. uncovered that a single substitution in the bovine influenza H5N1 haemagglutinin protein swi...
Responding to extreme climates
A recent study found that soil microbial communities show consistent and predictable responses to extreme climatic events.
Commensals find their niche
A recent study shows that the commensal bacterium Lactiplantibacillus plantarum recognizes the foregut of the fruit fly as...
Author Correction: Examining the healthy human microbiome concept
APC Microbiome Ireland, University College Cork, Cork, IrelandRaphaela Joos, Katy Boucher, Aonghus Lavelle, Marcus J. Clae...
Gut phages fuel food addiction
Gut phages fuel food addiction
In this study, Castells-Nobau et al. show that bacteriophages present in the gut microbiome contribute to the regulation o...
Linking innate immune evasion to pandemic potential
In this journal club, Lucy Thorne discusses a paper that compares pandemic and non-pandemic HIV and shows that the ability...
Campylobacter spreads colorectal cancer
Campylobacter spreads colorectal cancer
This study shows that the Campylobacter jejuni-derived genotoxin named cytolethal distending toxin promotes colorectal can...
Metagenomics for drug discovery
In this study, Padhi et al. demonstrate the potential of metagenomics-based approaches for the discovery of natural produc...
Methanogens implicated by DNA evidence
Methanogens implicated by DNA evidence
This Genome Watch article highlights recent findings that expand the known diversity of methanogenic archaea and the metag...
Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions
Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions
Shigella sonnei is a major cause of diarrhoea globally and is increasing in prevalence relative to other Shigella because ...
The consequences of SARS-CoV-2 within-host persistence
The consequences of SARS-CoV-2 within-host persistence
SARS-CoV-2 causes an acute respiratory tract infection that resolves in most people in less than a month. Yet some people ...
Antibiotic-recalcitrant Salmonella during infection
Antibiotic-recalcitrant Salmonella during infection
Antibiotic-recalcitrant infections, defined as the prolonged carriage of pathogenic bacteria even in the presence of antib...
Predicting phage–host specificity
In a recent study, Gaborieau, Vaysset, Tesson et al. developed a method to predict phage–host specificity using geno...
Designer viral receptors
In a recent study, Liu, Huang, Guo, McCallum et al. present a method to create functional, customized coronavirus receptor...
Iron gatekeeper in malaria
Loveridge and Sigala uncover a divalent metal transporter that is required for cellular iron metabolism in Plasmodium falc...
Hepatitis B and D virus entry
Hepatitis B and D virus entry
Hepatitis B virus (HBV) entry is the initial step of viral infection, leading to the formation of covalently closed circul...
Gut microbiota clocks in stress
Gut microbiota clocks in stress
In this study, Tofani et al. demonstrate that the gut microbiota regulates stress responsiveness in mice via the circadian...
Waning resistance
This study provides insights into how adaptive changes in evolved microbial communities can affect pathogen invasion.
A mimic targets intracellular Staphylococcus aureus
In this study, Ge et al. develop a mimic of natural killer cells to target and eliminate intracellular Staphylococcus aureus.
A river of resistant genes uncovered by metagenomics
A river of resistant genes uncovered by metagenomics
This Genome Watch discusses the use of metagenomic sequencing to investigate resistome dynamics in river ecosystems and th...
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