×
Close
註冊
登入
主页
用户
博客
照片
视频
医学图书S馆
医学图书M馆
医学图书D馆
医学术语
群组
活动
用户工具
用户指南
问答
谁看过我
反馈
语言
English
中文
推广
×
Close
CN1699 Our Business - Guide for Agents
分类
Biophysics
7881
Global Medical University
4882
Allergy
1738
Anatomy & Morphology
1496
Andrology
414
Anesthesia & Intensive Care
1185
Anesthesiology
5284
Audiology & Speech-Language Pathology
317
Behavioral Sciences
100
Biochemical Research Methods
6609
Biochemistry & Molecular Biology
28676
Biodiversity Conservation
277
Biology
8019
Biotechnology & Applied Microbiology
7905
Cardiac & Cardiovascular Systems
30136
Cardiovascular & Respiratory Systems
1363
Cell & Tissue Engineering
633
Cell Biology
10599
Chemistry, Analytical
4113
Chemistry, Applied
10888
Chemistry, Medicinal
8322
Chemistry, Multidisciplinary
18292
Clinical Immunology & Infectious Disease
424
Clinical Medicine
8600
Clinical Neurology
15860
Clinical Psychology & Psychiatry
1262
Critical Care Medicine
3054
Dentistry, Oral Surgery & Medicine
12569
Dermatology
7528
Developmental Biology
6826
Ecology
637
Education, Scientific Disciplines
1826
Emergency Medicine
3857
Endocrinology, Metabolism & Nutrition
22927
Engineering, Biomedical
3479
Entomology
414
Environmental Medicine & Public Health
4532
Evolutionary Biology
245
Gastroenterology & Hepatology
11495
General & Internal Medicine
6855
Genetics & Heredity
14387
Geriatrics & Gerontology
4883
Gerontology
324
Health Care Sciences & Services
15210
Health Policy & Services
568
Hematology
5320
Immunology
24226
Infectious Diseases
13367
Integrative & Complementary Medicine
2658
Medical Ethics
1114
Medical Informatics
2033
Medical Laboratory Technology
433
Medicine, General & Internal
43645
Medicine, Legal
470
Medicine, Research & Experimental
17065
Microbiology
22327
Mycology
0
Nanoscience & Nanotechnology
4884
Neuroimaging
1224
Neurology
4287
Neurosciences
37990
Nursing
9057
Nutrition & Dietetics
7687
Obstetrics & Gynecology
7885
Oncology
50646
Ophthalmology
9261
Optics
3884
Orthopedics
11064
Orthopedics, Rehabilitation & Sports Medicine
1670
Otolaryngology
1464
Otorhinolaryngology
4675
Parasitology
1009
Pathology
4727
Pediatrics
20579
Peripheral Vascular Disease
4507
Pharmacology & Pharmacy
33059
Pharmacology/Toxicology
11838
Physiology
8762
Polymer Science
525
Primary Health Care
774
Psychiatry
18494
Psychology
4902
Psychology, Applied
81
Psychology, Biological
315
Psychology, Clinical
759
Psychology, Developmental
210
Psychology, Educational
132
Psychology, Experimental
112
Psychology, Mathematical
0
Psychology, Multidisciplinary
1546
Psychology, Psychoanalysis
41
Psychology, Social
106
Public Health & Health Care Science
2164
Public, Environmental & Occupational Health
26519
Quantum Science & Technology
0
Radiology, Nuclear Medicine & Imaging
11753
Radiology, Nuclear Medicine & Medical Imaging
7580
Rehabilitation
2880
Remote Sensing
0
Reproductive Biology
2680
Reproductive Medicine
1125
Research/Laboratory Medicine & Medical Technology
3796
Respiratory System
6869
Rheumatology
5577
Social Sciences, Biomedical
1137
Substance Abuse
2604
Surgery
32455
Toxicology
4123
Transplantation
917
Tropical Medicine
314
Urology & Nephrology
12403
Veterinary Sciences
35
Virology
2320
Zoology
0
渠道
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
205
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
0
CURRENT OPINION IN CHEMICAL BIOLOGY
258
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
274
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
4793
NATURE STRUCTURAL & MOLECULAR BIOLOGY
515
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE
24
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
0
BIOINTERPHASES
55
JOURNAL OF BIOMECHANICS
946
PHOTOCHEMISTRY AND PHOTOBIOLOGY
170
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
433
CELL BIOCHEMISTRY AND BIOPHYSICS
208
SCI时时刷
search
全部
推荐
+
Thermodynamic Integration Combined with Molecular Dynamic Simulations to Explore the Cross‐Resistance Mechanism of Isoniazid and Ethionamide
Abstract Tuberculosis is an ancient disease of mankind, and its causative bacterium is Mycobacterium tuberculosis. Isoniaz...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
The Dynamic Basis of Structural Order in Proteins
Abstract We compare the sequences of folded and intrinsically disordered proteins, using bioinformatic methods recently de...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
The X‐ray crystal structure of human A15C neuroglobin reveals both native/de novo disulfide bonds and unexpected ligand‐binding sites
Abstract Human neuroglobin (Ngb) contains a heme group and three Cys residues (Cys46, Cys55 and Cys120) in the polypeptide...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
In‐depth analysis of amino acid and nucleotide sequences of Hsp60: how conserved is this protein?
Abstract Chaperonin Hsp60, as a protein found in all organisms, is of great interest in medicine, since it is present in m...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Dynamics in an unusual acyl carrier protein from a ladderane lipid‐synthesizing organism
Abstract Anaerobic ammonium-oxidizing (anammox) bacteria express a distinct acyl carrier protein implicated in the biosynt...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Cover Image, Volume 90, Issue 1
Reverse Cover: © Science Photo Library RF/Getty Images
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Identification, analysis, and modeling of the YUCCA protein family genome‐wide in Coffea canephora
Abstract Auxin is involved in almost every aspect of plant growth and development, from embryogenesis to senescence. Indol...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Molecular dynamics and structural analysis of the binding of COP1 E3 ubiquitin ligase to β‐catenin and TRIB pseudokinases
Abstract Tribbles pseudokinases, TRIB1, TRIB2, and TRIB3 bind to Constitutive Photomorphogenic Protein 1 (COP1) E3 ligase ...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Crystal structure of O‐ureidoserine racemase found in the D‐cycloserine biosynthetic pathway
Abstract O-Ureidoserine racemase (DcsC) is an enzyme found from the biosynthetic gene cluster of antitubercular agent D-cy...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Isolation and characterization of ACE‐I inhibitory peptides from ribbonfish for a potential inhibitor of the main protease of SARS‐CoV‐2; an in‐silico analysis.
Abstract Recently, multi-functional fish peptides (FWPs) have gained a lot of attention because of their different biologi...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Issue Information ‐ Forthcoming
PDF ShareShare Please review our Terms and Conditions of Use...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Issue Information ‐ Table of Content
Volume 89, Issue 12 p. 1603-1606 PDF ShareShare ...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Wool fiber curvature is correlated with abundance of K38 and specific keratin associated proteins
Abstract Curvature in mammalian fibers, such as wool and human hair, is an important feature of the functional trait of co...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Scaling‐up a fragment‐based protein‐protein interaction method using a human reference interaction set
Abstract Protein-protein interactions (PPIs) are essential in understanding numerous aspects of protein function. Here, we...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Assessment of domain interactions in the fourteenth round of the Critical Assessment of Structure Prediction (CASP14)
error_outline You have to enabl...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
In Memoriam of Narayanaswamy Srinivasan (1962‐2021)
Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis St...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Substrate‐Assisted Activation and Selectivity of the Bacterial RavD Effector Deubiquitinylase
Abstract Deubiquitinylases (DUBs) catalyze the specific cleavage of ubiquitin linkages at distinct protein substrates. Pat...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
A novel chimeric protein with enhanced cytotoxic effects on breast cancer in vitro and in vivo
Abstract In our previous study, we reported the design and recombinant production of the p28-apoptin as a novel chimeric p...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Molecular insights into the inhibition of glutamate dehydrogenase by the dicarboxylic acid metabolites
Abstract Glutamate dehydrogenase (GDH) is a salient metabolic enzyme which catalyzes the NAD+- or NADP+-dependent reversib...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
A C‐term truncated EIF2Bγ protein encoded by an intronically polyadenylated isoform introduces unfavorable EIF2Bγ‐EIF2γ interactions
Abstract Eukaryotic translation initiates upon recruitment of the EIF2-GTP·Met-tRNAi ternary complex (TC) to the ribo...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Molecular investigation of the tandem Tudor domain and plant homeodomain histone binding domains of the epigenetic regulator UHRF2
Abstract Ubiquitin-like containing PHD and ring finger (UHRF)1 and UHRF2 are multidomain epigenetic proteins that play a c...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
The non‐prion SUP35 preexists in large chaperone‐containing molecular complexes
Abstract Prions, misfolded proteins that aggregate, cause an array of progressively deteriorating conditions to which curr...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Low‐frequency collective motion of DNA‐binding domain defines p53 function
Abstract Most mutations in the DNA-binding domain (DBD) of p53 inactivates or rescues the protein function interacting wit...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Pseudokinases repurpose flexibility signatures associated with the protein kinase fold for noncatalytic roles
Abstract The bilobal protein kinase-like fold in pseudokinases lack one or more catalytic residues, conserved in canonical...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Chemical reactivity and binding interactions in ribonucleic acid‐peptide complexes
Abstract The covalent and noncovalent backbone binding interactions in RNA-peptide complexes were studied by DFT methods. ...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Tripeptide loop closure: a detailed study of reconstructions based on Ramachandran distributions
Abstract Tripeptide loop closure (TLC) is a standard procedure to reconstruct protein backbone conformations, by solving a...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Boosting the analysis of protein interfaces with Multiple Interface String Alignments: illustration on the spikes of coronaviruses
Abstract We introduce Multiple Interface String Alignment (MISA), a visualization tool to display coherently various seque...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Functional antibody characterization via direct structural analysis and information‐driven protein‐protein docking
Abstract Detailed description of the mechanism of action of the therapeutic antibodies is essential for the functional cha...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Molecular investigation of the TTD and PHD histone binding domains of the epigenetic regulator UHRF2.
Abstract UHRF1 and UHRF2 are multi-domain epigenetic proteins that play a critical role in bridging crosstalk between hist...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
Mycobacterial membrane protein Large 3‐like‐family proteins in bacteria, protozoa, fungi, plants, and animals: A bioinformatics and structural investigation
Abstract Lipid transporters play an important role in most if not all organisms, ranging from bacteria to humans. For exam...
Proteins-structure Function And Bioinformatics
comment
0
thumb_up
0
阅读更多
Modal title
×
Modal title
×
分享
登入
Global News and Health Forum
Join Now!
馬上登入
記住我
忘記密碼?
或者使用
Linkedin