SCI时时刷

search
Nanosuspensions technology as a master key for nature products drug delivery and In vivo fate
Available online 18 March 2023, 106425Author links open overlay panel, , , AbstractThe drug nanosuspensions is a universal...
Design, synthesis, and biological screening of a series of pyrazolo [1,5-a]quina-zoline derivatives as SIRT6 activators
Available online 12 March 2023, 106424Author links open overlay panel, , , , , ABSTRACTSIRT6 has emerged as a novel therap...
A profile of SGLT-2 inhibitors in hyponatremia: The evidence to date
Hyponatremia is the most common electrolyte disorder in clinical practice, which may lead to life-threatening complication...
Pharmacokinetics and pharmacodynamics of imatinib for optimal drug repurposing from cancer to COVID-19
Volume 184, 1 May 2023, 106418Author links open overlay panel, , , , , , , , , , , , , Highlights•This is the first study ...
Albumin-binding DARPins as scaffold improve the hypoglycemic and anti-obesity effects of exendin-4 in vivo
Volume 185, 1 June 2023, 106422Author links open overlay panel, , , , Highlights•Albumin-binding DARPins can be used as a ...
Evaluation of the 18F-labeled analog of the therapeutic all-D-enantiomeric peptide RD2 for amyloid β imaging
Volume 184, 1 May 2023, 106421Author links open overlay panel, , , , , , , , , , , , AbstractPositron emission tomography ...
Implementation of Quality by Design (QbD) for development of bilayer tablets
Bilayer tablets offer various drug release profiles for individual drugs incorporated in each layer of a bilayer tablet, w...
Discovery of ANO1 Inhibitors based on Machine learning and molecule docking simulation approaches
Calcium-activated chloride channels (CaCCs) are chloride channels that are regulated according to intracellular calcium io...
Dissolving microneedle patches-mediated percutaneous delivery of tetramethylpyrazine for rheumatoid arthritis treatment
Recently, transdermal treatment of rheumatoid arthritis (RA) has received increasing attention due to the advantages of im...
Mechanistic insights into the effect of drug content on adhesive properties of transdermal patch containing lidocaine
This study aims to shed light on the relationship between drug content and adhesive properties in drug-in-adhesive transde...
Pyrazole and pyrazoline derivatives as antimalarial agents: A key review
Volume 183, 1 April 2023, 106365Author links open overlay panel, , , Review highlights•The development of drug resistance ...
Design, synthesis and cytotoxic evaluation of a selective serotonin reuptake inhibitor (SSRI) by virtual screening
Volume 183, 1 April 2023, 106403Author links open overlay panel, , Highlights•A potencial SSRI (18a) was designed rational...
Preparation of hyaluronic acid-loaded Harmine polymeric micelles and in vitro effect anti-breast cancer
Volume 183, 1 April 2023, 106388Author links open overlay panel, , , , AbstractAimsTo prepare hyaluronic acid-loaded Harmi...
Development of a population pharmacokinetic model and optimal dosing regimen of leflunomide in Korean population
PurposeLeflunomide is an immunosuppressive drug indicated for the treatment of rheumatoid arthritis (RA). While the pharma...
The impact of possible improper use on the performance in vitro of NEXThaler in comparison with Ellipta inhaler
The correct use of dry powder inhalers by the patients is essential to ensure effective treatment and management of the di...