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Biomedicines, Vol. 11, Pages 90: The Association between Vitamin D and the Components of Male Fertility: A Systematic Review
Objective: Previous systematic reviews of the effects of vitamin D on the components of male fertility have been inconclus...
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Biomedicines, Vol. 11, Pages 88: HAT- and HDAC-Targeted Protein Acetylation in the Occurrence and Treatment of Epilepsy
Epilepsy is a common and severe chronic neurological disorder. Recently, post-translational modification (PTM) mechanisms,...
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Biomedicines, Vol. 11, Pages 89: Central Sensitization and Psychological State Distinguishing Complex Regional Pain Syndrome from Other Chronic Limb Pain Conditions: A Cluster Analysis Model
Complex regional pain syndrome (CRPS) taxonomy has been updated with reported subtypes and is defined as primary pain alon...
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Biomedicines, Vol. 11, Pages 86: Inadequacy of Vitamin D Does Not Interfere with Body Weight Loss in Women of Reproductive Age after Roux-en-Y Gastric Bypass
Objective: To assess the influence of vitamin D on body weight loss in women who had previously undergone Roux-en-Y gastri...
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Biomedicines, Vol. 11, Pages 87: Toxin-like Peptides from the Bacterial Cultures Derived from Gut Microbiome Infected by SARS-CoV-2—New Data for a Possible Role in the Long COVID Pattern
It has been 3 years since the beginning of the SARS-CoV-2 outbreak, however it is as yet little known how to care for the ...
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Biomedicines, Vol. 11, Pages 84: A Review on Music Interventions for Frontotemporal Aphasia and a Proposal for Alternative Treatments
Frontotemporal dementia (FTD) is a rare neurodegenerative disease, characterized by behavioral and language impairments. P...
Biomedicines
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Biomedicines, Vol. 11, Pages 85: Potential Inhibitors of SARS-CoV-2 Main Protease (Mpro) Identified from the Library of FDA-Approved Drugs Using Molecular Docking Studies
The Corona Virus Infectious Disease-2019 (COVID-19) outbreak originated at Wuhan, China, in December 2019. It has already ...
Biomedicines
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Biomedicines, Vol. 11, Pages 83: Impact of Liver Metastases and Number of Metastatic Sites on Immune-Checkpoint Inhibitors Efficacy in Patients with Different Solid Tumors: A Retrospective Study
Background: ICIs have dramatically improved patient outcomes in different malignancies. However, the impact of liver metas...
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Biomedicines, Vol. 11, Pages 77: FT3 to FT4 Conversion Ratio May Be an Independent Prognostic Factor in Pancreatic Cancer Patients
Preclinical evidence suggests that T4 can promote tumor growth while T3 can act conversely; therefore, the fT3 and fT4 con...
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Biomedicines, Vol. 11, Pages 76: FIB-4 Index and Neutrophil-to-Lymphocyte-Ratio as Death Predictor in Coronary Artery Disease Patients
Nonalcoholic fatty liver disease (NAFLD)-associated liver fibrosis is likely related to coronary artery disease (CAD) by t...
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Biomedicines, Vol. 11, Pages 81: Gingival Overgrowths Revealing PTEN Hamartoma Tumor Syndrome: Report of Novel PTEN Pathogenic Variants
PTEN hamartoma tumor syndrome (PHTS), is a spectrum of disorders caused by mutations of PTEN, in which non-cancerous growt...
Biomedicines
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Biomedicines, Vol. 11, Pages 82: Onset of Action of Selected Second-Generation Antipsychotics (Pines)–A Systematic Review and Meta-Analyses
Recommendations for duration of treatment with antipsychotics before considering a switch vary from 2 to 8 weeks, although...
Biomedicines
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Biomedicines, Vol. 11, Pages 80: The Effects of Transcranial Direct Current Stimulation in Obsessive–Compulsive Disorder Symptoms: A Meta-Analysis and Integrated Electric Fields Modeling Analysis
Transcranial direct current stimulation (tDCS) has been showing promising effects for the treatment of obsessive&ndash...
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Biomedicines, Vol. 11, Pages 70: New Opportunities in Heart Failure with Preserved Ejection Fraction: From Bench to Bedside… and Back
Heart failure with preserved ejection fraction (HFpEF) is a growing public health problem in nearly 50% of patients with h...
Biomedicines
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Biomedicines, Vol. 11, Pages 75: Ketamine Inhalation Alters Behavior and Lower Urinary Tract Function in Mice
We aimed to evaluate behavioral and lower urinary tract changes in mice using a novel ketamine inhalation model mimicking ...
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Biomedicines, Vol. 11, Pages 73: New Approach to Chronic Back Pain Treatment: A Case Control Study
Background and objective: Our study compares the clinical outcome of chronic low back pain present for over six months tre...
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Biomedicines, Vol. 11, Pages 74: Cannabidiol Decreases Intestinal Inflammation in the Ovariectomized Murine Model of Postmenopause
Cannabidiol (CBD) (25 mg/kg peroral) treatment was shown to improve metabolic outcomes in ovariectomized (OVX) mice defici...
Biomedicines
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Biomedicines, Vol. 11, Pages 61: The 2-Oxoglutarate Carrier Is S-Nitrosylated in the Spinal Cord of G93A Mutant hSOD1 Mice Resulting in Disruption of Mitochondrial Glutathione Transport
Mitochondrial oxidative stress and dysfunction are strongly implicated in the pathogenesis of amyotrophic lateral sclerosi...
Biomedicines
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Biomedicines, Vol. 11, Pages 69: Molecular Subtyping in Muscle-Invasive Bladder Cancer on Predicting Survival and Response of Treatment
Molecular classifications for urothelial bladder cancer appear to be promising in disease prognostication and prediction. ...
Biomedicines
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Biomedicines, Vol. 11, Pages 68: Indisulam Reduces Viability and Regulates Apoptotic Gene Expression in Pediatric High-Grade Glioma Cells
Pediatric high-grade glioma (pHGG) is one of the most aggressive brain tumors. Treatment includes surgery, radiotherapy, c...
Biomedicines
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Biomedicines, Vol. 11, Pages 66: Doppler Ultrasound Selection and Follow-Up of the Internal Mammary Artery as Coronary Graft
The impact of coronary artery disease (CAD) on all-cause mortality and overall disabilities is well-established. Percutane...
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Biomedicines, Vol. 11, Pages 67: GraphATT-DTA: Attention-Based Novel Representation of Interaction to Predict Drug-Target Binding Affinity
Drug-target binding affinity (DTA) prediction is an essential step in drug discovery. Drug-target protein binding occurs a...
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Biomedicines, Vol. 11, Pages 64: The Latest Approach of Immunotherapy with Endosomal TLR Agonists Improving NK Cell Function: An Overview
Toll-like receptors (TLRs) are the most well-defined pattern recognition receptors (PRR) of several cell types recognizing...
Biomedicines
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Biomedicines, Vol. 11, Pages 65: Low-Dose Metformin Treatment Reduces In Vitro Growth of the LL/2 Non-small Cell Lung Cancer Cell Line
Lung cancer maintains a relatively small survival rate (~19%) over a 5-year period and up to 80–85% of all lung ...
Biomedicines
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Biomedicines, Vol. 11, Pages 62: Patisiran Enhances Muscle Mass after Nine Months of Treatment in ATTRv Amyloidosis: A Study with Bioelectrical Impedance Analysis and Handgrip Strength
Background and aims. Hereditary transthyretin amyloidosis with polyneuropathy (ATTRv) is caused by mutations in the TTR ge...
Biomedicines
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Biomedicines, Vol. 11, Pages 63: FDG PET Imaging of the Pain Matrix in Neuropathic Pain Model Rats
Pain is an unpleasant subjective experience that is usually modified by complex multidimensional neuropsychological proces...
Biomedicines
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Biomedicines, Vol. 11, Pages 60: Gamma-Synuclein Dysfunction Causes Autoantibody Formation in Glaucoma Patients and Dysregulation of Intraocular Pressure in Mice
Dysregulation of intraocular pressure (IOP) is one of the main risk factors for glaucoma. γ-synuclein is a membe...
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Biomedicines, Vol. 11, Pages 57: The Effect of Earthing Mat on Stress-Induced Anxiety-like Behavior and Neuroendocrine Changes in the Rat
Grounding is a therapeutic technique that involves doing activities that “ground” or electrically reco...
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Biomedicines, Vol. 11, Pages 56: The Role of LINC01564, RAMS11, CBX4 and TOP2A in Hepatocellular Carcinoma
Background: Hepatocellular carcinoma (HCC) is the most common histologic type of primary liver cancers worldwide. Hepatiti...
Biomedicines
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Biomedicines, Vol. 11, Pages 55: Methylenetetrahydrofolate Reductase 677T Allele Is a Risk Factor for Arterial Thrombosis in Chinese Han Patients with Antiphospholipid Syndrome
Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by the persistent presence of antiphosphol...
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