SCI时时刷

search
+
Silencing DOCK2 Attenuates Cardiac Fibrosis Following Myocardial Infarction in Mice Via Targeting PI3K/Akt and Wnt/β-Catenin Pathways
Silencing DOCK2 Attenuates Cardiac Fibrosis Following Myocardial Infarction in Mice Via Targeting PI3K/Akt and Wnt/β-Catenin Pathways
Cardiac fibrosis following myocardial infarction (MI) seriously affects the prognosis and survival rate of patients. This ...
Comprehensive Quality Analysis of Conventional and Novel Biomarkers in Diagnosing and Predicting Prognosis of Coronary Artery Disease, Acute Coronary Syndrome, and Heart Failure, a Comprehensive Literature Review
Comprehensive Quality Analysis of Conventional and Novel Biomarkers in Diagnosing and Predicting Prognosis of Coronary Artery Disease, Acute Coronary Syndrome, and Heart Failure, a Comprehensive Literature Review
Coronary artery disease (CAD), acute coronary syndrome (ACS), and heart failure (HF) are major global health issues with h...
Blood Pressure Variability After Non-invasive Low-level Tragus Stimulation in Acute Heart Failure
Blood Pressure Variability After Non-invasive Low-level Tragus Stimulation in Acute Heart Failure
Higher blood pressure (BP) variability (BPV) was shown to be strong predictors of poor cardiovascular outcomes in heart fa...
High-intensity Focused Ultrasound-A New Choice to Conduct Pulmonary Artery Denervation
High-intensity Focused Ultrasound-A New Choice to Conduct Pulmonary Artery Denervation
This research aimed to explore whether high-intensity focused ultrasound (HIFU) could conduct pulmonary artery denervation...
Plasma Biomarker Screening Based on Proteomic Signature of Patients with Resistant Hypertension
Plasma Biomarker Screening Based on Proteomic Signature of Patients with Resistant Hypertension
Resistant hypertension (RH) poses a significant health challenge, yet its underlying pathogenesis remains unclear. This st...
Circulating circ_0069094 is Correlated with the Present and Endothelial Injury of Acute Coronary Syndrome
Circulating circ_0069094 is Correlated with the Present and Endothelial Injury of Acute Coronary Syndrome
To investigate the impacts of circ_0069094 on acute coronary syndrome. Real-time polymerase chain reaction was used to det...
TMAO Impairs Mouse Aortic Vasodilation by Inhibiting TRPV4 Channels in Endothelial Cells
TMAO Impairs Mouse Aortic Vasodilation by Inhibiting TRPV4 Channels in Endothelial Cells
Trimethylamine oxide (TMAO) is an intestinal flora metabolite associated with risk of cardiovascular diseases. Transient r...
Morphological Features of the Vertebrobasilar System Predict Ischemic Stroke Risk in Spontaneous Vertebral Artery Dissection
Morphological Features of the Vertebrobasilar System Predict Ischemic Stroke Risk in Spontaneous Vertebral Artery Dissection
The vertebral artery’s morphological characteristics are crucial in spontaneous vertebral artery dissection (sVAD). ...
Differential Expression of mRNA in Peripheral Blood Mononuclear Cells May Predict Postoperative Atrial Fibrillation in Coronary Artery Bypass Surgery Patients
Differential Expression of mRNA in Peripheral Blood Mononuclear Cells May Predict Postoperative Atrial Fibrillation in Coronary Artery Bypass Surgery Patients
Postoperative Atrial Fibrillation (POAF) frequently follows Coronary Artery Bypass Grafting (CABG) surgery. This prospecti...
Short-term S100A8/A9 Blockade Promotes Cardiac Neovascularization after Myocardial Infarction
Short-term S100A8/A9 Blockade Promotes Cardiac Neovascularization after Myocardial Infarction
Acute-phase inhibition of the pro-inflammatory alarmin S100A8/A9 improves cardiac function post-myocardial infarction (MI)...
Prediction of Left Ventricle Pressure Indices Via a Machine Learning Approach Combining ECG, Pulse Oximetry, and Cardiac Sounds: a Preclinical Feasibility Study
Prediction of Left Ventricle Pressure Indices Via a Machine Learning Approach Combining ECG, Pulse Oximetry, and Cardiac Sounds: a Preclinical Feasibility Study
Heart failure (HF) is defined as the inability of the heart to meet body oxygen demand requiring an elevation in left vent...
Gut Microbiota as Predictive Biomarker for Chronic Heart Failure in Patients with Different Nutritional Risk
Gut Microbiota as Predictive Biomarker for Chronic Heart Failure in Patients with Different Nutritional Risk
To examine the relationship between gut microbiota and disease development in chronic heart failure patients with differen...
Vaccarin Ameliorates Doxorubicin-Induced Cardiotoxicity via Inhibition of p38 MAPK Mediated Mitochondrial Dysfunction
Vaccarin Ameliorates Doxorubicin-Induced Cardiotoxicity via Inhibition of p38 MAPK Mediated Mitochondrial Dysfunction
Doxorubicin is a frequently used chemotherapeutic agent for treating various malignancies. However, it leads to severe car...
CRISPR/Cas9 Mediated Deletion of the Uox Gene Generates a Mouse Model of Hyperuricemia with Multiple Complications
CRISPR/Cas9 Mediated Deletion of the Uox Gene Generates a Mouse Model of Hyperuricemia with Multiple Complications
Hyperuricemia is a common metabolic disorder with severe complications. We aimed to develop a mouse model for spontaneous ...
Modulating the Expression of Exercise-induced lncRNAs: Implications for Cardiovascular Disease Progression
Modulating the Expression of Exercise-induced lncRNAs: Implications for Cardiovascular Disease Progression
Recent research shows exercise is good for heart health, emphasizing the importance of physical activity. Sedentary behavi...
Novel Genetic Variants Associated with Primary Myocardial Fibrosis in Sudden Cardiac Death Victims
Novel Genetic Variants Associated with Primary Myocardial Fibrosis in Sudden Cardiac Death Victims
Myocardial fibrosis is a common finding in victims of sudden cardiac death (SCD). Whole exome sequencing was performed in ...
Extracellular Vesicles to Predict Outcomes After Transcatheter Aortic Valve Implantation – a Prospective, Multicenter Cohort Study
Extracellular Vesicles to Predict Outcomes After Transcatheter Aortic Valve Implantation – a Prospective, Multicenter Cohort Study
Transcatheter aortic valve implantation (TAVI) is an established treatment for aortic stenosis (AS) in patients at interme...
Mitochondria-Associated Organelle Crosstalk in Myocardial Ischemia/Reperfusion Injury
Mitochondria-Associated Organelle Crosstalk in Myocardial Ischemia/Reperfusion Injury
Organelle damage is a significant contributor to myocardial ischemia/reperfusion (I/R) injury. This damage often leads to ...
Exosome is a Fancy Mobile Sower of Ferroptosis
Exosome is a Fancy Mobile Sower of Ferroptosis
Exosomes, nano-sized small extracellular vesicles, have been shown to serve as mediators between intercellular communicati...
Differential Effects of Pharmacologic and Mechanical Support on Right-Left Ventricular Coupling
Differential Effects of Pharmacologic and Mechanical Support on Right-Left Ventricular Coupling
Percutaneous ventricular assist devices are increasingly relied on to maintain perfusion for cardiogenic shock patients. O...
Protective Mechanisms of SGLTi in Ischemic Heart Disease
Protective Mechanisms of SGLTi in Ischemic Heart Disease
Ischemic heart disease (IHD) is a common clinical cardiovascular disease with high morbidity and mortality. Sodium glucose...
Pathogenic Autoimmunity in Atherosclerosis Evolves from HSP60-Reactive CD4 + T Cells
Pathogenic Autoimmunity in Atherosclerosis Evolves from HSP60-Reactive CD4 + T Cells
Clinical evidence suggests anti-Hsp60 antibodies could contribute to atherosclerosis (AS) development, with unclear mechan...
The Genetic Factors Influencing Cardiomyopathies and Heart Failure across the Allele Frequency Spectrum
The Genetic Factors Influencing Cardiomyopathies and Heart Failure across the Allele Frequency Spectrum
Heart failure (HF) remains a major cause of mortality and morbidity worldwide. Understanding the genetic basis of HF allow...
A Novel Swine Model for Inducing Functional Tricuspid Valve Regurgitation
A Novel Swine Model for Inducing Functional Tricuspid Valve Regurgitation
Functional tricuspid regurgitation (FTR) is the most common TR, although experimental models to effectively study it are s...
Increased Expression of Inactive Rhomboid Protein 2 in Circulating Monocytes after Acute Myocardial Infarction
Increased Expression of Inactive Rhomboid Protein 2 in Circulating Monocytes after Acute Myocardial Infarction
Increased TNF-α levels following acute myocardial infarction (AMI) contribute to impaired recovery of myocardial func...
The activation of P38MAPK Signaling Pathway Impedes the Delivery of the Cx43 to the Intercalated Discs During Cardiac Ischemia–Reperfusion Injury
The activation of P38MAPK Signaling Pathway Impedes the Delivery of the Cx43 to the Intercalated Discs During Cardiac Ischemia–Reperfusion Injury
Ischemic heart disease is caused by coronary artery occlusion. Despite the increasing number and success of interventions ...
Isolated Perfused Hearts for Cardiovascular Research: An Old Dog with New Tricks
Isolated Perfused Hearts for Cardiovascular Research: An Old Dog with New Tricks
In modern cardiovascular research, isolated perfused hearts have become cost-effective and highly reproducible tools to in...
Predictive Value of 5-Methoxytryptophan on Long-Term Clinical Outcome after PCI in Patients with Acute Myocardial Infarction-a Prospective Cohort Study
Predictive Value of 5-Methoxytryptophan on Long-Term Clinical Outcome after PCI in Patients with Acute Myocardial Infarction-a Prospective Cohort Study
In recent years, 5-Methoxytryptophan (5-MTP) has been identified as an endothelial factor with vaso-protective and anti-in...
Polygenic Risk Score Assessment for Coronary Artery Disease in Asian Indians
Polygenic Risk Score Assessment for Coronary Artery Disease in Asian Indians
We evaluated the performance of various polygenic risk score (PRS) models derived from European (EU), South Asian (SA), an...
RyR2 Stabilizer Attenuates Cardiac Hypertrophy by Downregulating TNF-α/NF-κB/NLRP3 Signaling Pathway through Inhibiting Calcineurin
RyR2 Stabilizer Attenuates Cardiac Hypertrophy by Downregulating TNF-α/NF-κB/NLRP3 Signaling Pathway through Inhibiting Calcineurin
The effect of Ryanodine receptor2 (RyR2) and its stabilizer on cardiac hypertrophy is not well known. C57/BL6 mice underwe...
阅读更多
format_indent_increase