×
Close
註冊
登入
主页
用户
博客
照片
视频
医学图书S馆
医学图书M馆
医学图书D馆
医学术语
群组
活动
用户工具
用户指南
问答
谁看过我
反馈
语言
English
中文
推广
×
Close
CN1699 Our Business - Guide for Agents
分类
Geriatrics & Gerontology
5617
Global Medical University
6074
Allergy
1886
Anatomy & Morphology
1685
Andrology
414
Anesthesia & Intensive Care
1408
Anesthesiology
6191
Audiology & Speech-Language Pathology
358
Behavioral Sciences
111
Biochemical Research Methods
8119
Biochemistry & Molecular Biology
33902
Biodiversity Conservation
366
Biology
9836
Biophysics
10790
Biotechnology & Applied Microbiology
9646
Cardiac & Cardiovascular Systems
35094
Cardiovascular & Respiratory Systems
1644
Cell & Tissue Engineering
766
Cell Biology
12159
Chemistry, Analytical
4649
Chemistry, Applied
12712
Chemistry, Medicinal
9574
Chemistry, Multidisciplinary
20851
Clinical Immunology & Infectious Disease
483
Clinical Medicine
9629
Clinical Neurology
18330
Clinical Psychology & Psychiatry
1679
Critical Care Medicine
3652
Dentistry, Oral Surgery & Medicine
15294
Dermatology
8009
Developmental Biology
7595
Ecology
655
Education, Scientific Disciplines
2191
Emergency Medicine
4689
Endocrinology, Metabolism & Nutrition
27880
Engineering, Biomedical
4151
Entomology
482
Environmental Medicine & Public Health
5403
Evolutionary Biology
288
Gastroenterology & Hepatology
13627
General & Internal Medicine
7955
Genetics & Heredity
17150
Gerontology
366
Health Care Sciences & Services
18058
Health Policy & Services
671
Hematology
5983
Immunology
28921
Infectious Diseases
15635
Integrative & Complementary Medicine
3230
Medical Ethics
1286
Medical Informatics
2681
Medical Laboratory Technology
433
Medicine, General & Internal
49689
Medicine, Legal
591
Medicine, Research & Experimental
20731
Microbiology
26879
Mycology
0
Nanoscience & Nanotechnology
5986
Neuroimaging
1495
Neurology
5251
Neurosciences
45689
Nursing
10570
Nutrition & Dietetics
8569
Obstetrics & Gynecology
9292
Oncology
59182
Ophthalmology
11230
Optics
5219
Orthopedics
12940
Orthopedics, Rehabilitation & Sports Medicine
2050
Otolaryngology
1697
Otorhinolaryngology
5409
Parasitology
1156
Pathology
5550
Pediatrics
24156
Peripheral Vascular Disease
5258
Pharmacology & Pharmacy
40952
Pharmacology/Toxicology
14139
Physiology
9836
Polymer Science
686
Primary Health Care
907
Psychiatry
23074
Psychology
5697
Psychology, Applied
113
Psychology, Biological
393
Psychology, Clinical
896
Psychology, Developmental
235
Psychology, Educational
149
Psychology, Experimental
147
Psychology, Mathematical
0
Psychology, Multidisciplinary
1697
Psychology, Psychoanalysis
41
Psychology, Social
122
Public Health & Health Care Science
2416
Public, Environmental & Occupational Health
30696
Quantum Science & Technology
0
Radiology, Nuclear Medicine & Imaging
14064
Radiology, Nuclear Medicine & Medical Imaging
8814
Rehabilitation
3236
Remote Sensing
0
Reproductive Biology
3335
Reproductive Medicine
1340
Research/Laboratory Medicine & Medical Technology
4498
Respiratory System
8227
Rheumatology
6731
Social Sciences, Biomedical
1316
Substance Abuse
2990
Surgery
38473
Toxicology
4729
Transplantation
953
Tropical Medicine
314
Urology & Nephrology
14840
Veterinary Sciences
35
Virology
2655
Zoology
0
渠道
AGING CELL
140
AGEING RESEARCH REVIEWS
0
EXPERIMENTAL GERONTOLOGY
820
GEROSCIENCE
671
IMMUNITY & AGEING
208
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
140
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
157
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
49
NEUROBIOLOGY OF AGING
572
AUSTRALASIAN JOURNAL ON AGEING
116
CLINICAL INTERVENTIONS IN AGING
350
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
135
EUROPEAN REVIEW OF AGING AND PHYSICAL ACTIVITY
94
GERIATRICS & GERONTOLOGY INTERNATIONAL
144
GERODONTOLOGY
78
GERONTOLOGY
234
JOURNAL OF AGING AND PHYSICAL ACTIVITY
351
ADVANCES IN GERONTOLOGY
119
AGEING INTERNATIONAL
171
ANNALS OF GERIATRIC MEDICINE AND RESEARCH
20
CANADIAN GERIATRICS JOURNAL
132
GERIATRICS
166
GERONTOLOGY AND GERIATRIC MEDICINE
63
INNOVATION IN AGING
61
JOURNAL OF FRAILTY & AGING
194
JOURNAL OF NUTRITION HEALTH & AGING
432
SCI时时刷
search
全部
推荐
+
Aging reduces liver resiliency by dysregulating Hedgehog signaling
Abstract Older age is a major risk factor for damage to many tissues, including liver. Aging undermines resiliency and imp...
Aging Cell
comment
0
thumb_up
0
Emerging rejuvenation strategies—Reducing the biological age
Abstract Several interventions have recently emerged that were proposed to reverse rather than just attenuate aging, but t...
Aging Cell
comment
0
thumb_up
0
Corrigendum to: Reevaluation of the effect of dietary restriction on different recombinant inbred lines of male and female mice
Archana Unnikrishnan, Stephanie Matyi, Karla Garret, Michelle Ranjo-Bishop, David B. Allison, Keisuke Ejima, Xiwei Chen, S...
Aging Cell
comment
0
thumb_up
0
Senescence‐induced changes in CD4 T cell differentiation can be alleviated by treatment with senolytics
Abstract Aging and senescence impact CD4 T helper cell (Th) subset differentiation during influenza infection. In the lung...
Aging Cell
comment
0
thumb_up
0
Chemically induced senescence in human stem cell‐derived neurons promotes phenotypic presentation of neurodegeneration
Abstract Modeling age-related neurodegenerative disorders with human stem cells are difficult due to the embryonic nature ...
Aging Cell
comment
0
thumb_up
0
Increased MFG‐E8 at neuromuscular junctions is an exacerbating factor for sarcopenia‐associated denervation
Abstract Sarcopenia is an important health problem associated with adverse outcomes. Although the etiology of sarcopenia r...
Aging Cell
comment
0
thumb_up
0
Physiological clearance of Aβ by spleen and splenectomy aggravates Alzheimer‐type pathogenesis
Abstract Background A previous study demonstrated that nearly 40%–60% of brain Aβ flows out into the peripher...
Aging Cell
comment
0
thumb_up
0
New lessons on TDP‐43 from old N. furzeri killifish
Abstract Frontotemporal dementia and amyotrophic lateral sclerosis are fatal and incurable neurodegenerative diseases link...
Aging Cell
comment
0
thumb_up
0
Late‐life exercise mitigates skeletal muscle epigenetic aging
Abstract There are functional benefits to exercise in muscle, even when performed late in life, but the contributions of e...
Aging Cell
comment
0
thumb_up
0
The age factor in optic nerve regeneration: Intrinsic and extrinsic barriers hinder successful recovery in the short‐living killifish
Abstract As the mammalian central nervous system matures, its regenerative ability decreases, leading to incomplete or non...
Aging Cell
comment
0
thumb_up
0
Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy
Abstract The “rejuvenating” effect of growth differentiation factor 11 (GDF11) is called into question recen...
Aging Cell
comment
0
thumb_up
0
Regulatory role of cathepsin L in induction of nuclear laminopathy in Alzheimer’s disease
Abstract Experimental and clinical therapies in the field of Alzheimer's disease (AD) have focused on elimination of extra...
Aging Cell
comment
0
thumb_up
0
A circular intronic RNA ciPVT1 delays endothelial cell senescence by regulating the miR‐24‐3p/CDK4/pRb axis
Abstract Circular RNAs (circRNAs) have been established to be involved in numerous processes in the human genome, but thei...
Aging Cell
comment
0
thumb_up
0
Deletion of SA β‐Gal+ cells using senolytics improves muscle regeneration in old mice
Abstract Systemic deletion of senescent cells leads to robust improvements in cognitive, cardiovascular, and whole-body me...
Aging Cell
comment
0
thumb_up
0
Loss of lamin‐B1 and defective nuclear morphology are hallmarks of astrocyte senescence in vitro and in the aging human hippocampus
Abstract The increase in senescent cells in tissues, including the brain, is a general feature of normal aging and age-rel...
Aging Cell
comment
0
thumb_up
0
Adaptive capacity to dietary Vitamin B12 levels is maintained by a gene‐diet interaction that ensures optimal life span
Abstract Diet regulates complex life-history traits such as longevity. For optimal lifespan, organisms employ intricate ad...
Aging Cell
comment
0
thumb_up
0
Inhibition of DNA methyltransferase aberrations reinstates antioxidant aging suppressors and ameliorates renal aging
Abstract DNA methylation alterations play mechanistic roles in aging; however, the epigenetic regulators/mediators causall...
Aging Cell
comment
0
thumb_up
0
Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes
Abstract Metformin, the most commonly prescribed anti-diabetes medication, has multiple reported health benefits, includin...
Aging Cell
comment
0
thumb_up
0
Phenotype correlations reveal the relationships of physiological systems underlying human ageing
Abstract Ageing is characterized by degeneration and loss of function across multiple physiological systems. To study the ...
Aging Cell
comment
0
thumb_up
0
Nogo receptor impairs the clearance of fibril amyloid‐β by microglia and accelerates Alzheimer’s‐like disease progression
Abstract Alzheimer's disease (AD) is characterized by the progressive accumulation of β-amyloid (Aβ)-containin...
Aging Cell
comment
0
thumb_up
0
Growth hormone receptor gene disruption in mature‐adult mice improves male insulin sensitivity and extends female lifespan
Abstract Studies in multiple species indicate that reducing growth hormone (GH) action enhances healthy lifespan. In fact,...
Aging Cell
comment
0
thumb_up
0
Cisd2 slows down liver aging and attenuates age‐related metabolic dysfunction in male mice
Abstract The liver plays a pivotal role in mammalian aging. However, the mechanisms underlying liver aging remain unclear....
Aging Cell
comment
0
thumb_up
0
α‐synuclein suppresses microglial autophagy and promotes neurodegeneration in a mouse model of Parkinson’s disease
Abstract The cell-to-cell transfer of α-synuclein (α-Syn) greatly contributes to Parkinson's disease (PD) path...
Aging Cell
comment
0
thumb_up
0
Induction of somatopause in adult mice compromises bone morphology and exacerbates bone loss during aging
Abstract Somatopause refers to the gradual declines in growth hormone (GH) and insulin-like growth factor-1 throughout agi...
Aging Cell
comment
0
thumb_up
0
α‐Synuclein antisense transcript SNCA‐AS1 regulates synapses‐ and aging‐related genes suggesting its implication in Parkinson's disease
Abstract SNCA protein product, α-synuclein, is widely renowned for its role in synaptogenesis and implication in bot...
Aging Cell
comment
0
thumb_up
0
Mitochondrial aconitase 1 regulates age‐related memory impairment via autophagy/mitophagy‐mediated neural plasticity in middle‐aged flies
Abstract Age-related memory impairment (AMI) occurs in many species, including humans. The underlying mechanisms are not f...
Aging Cell
comment
0
thumb_up
0
Sex‐specific accelerated decay in time/activity‐dependent plasticity and associative memory in an animal model of Alzheimer's disease
Abstract Clinical studies have shown that female brains are more predisposed to neurodegenerative diseases such as Alzheim...
Aging Cell
comment
0
thumb_up
0
Adiponectin alleviated Alzheimer‐like pathologies via autophagy‐lysosomal activation
Abstract Adiponectin (APN) deficiency has also been associated with Alzheimer-like pathologies. Recent studies have illumi...
Aging Cell
comment
0
thumb_up
0
miR‐125a‐5p increases cellular DNA damage of aging males and perturbs stage‐specific embryo development via Rbm38‐p53 signaling
Abstract An increasing number of men are fathering children at an older age than in the past. While advanced maternal age ...
Aging Cell
comment
0
thumb_up
0
Selective oxidative stress induces dual damage to telomeres and mitochondria in human T cells
Abstract Oxidative stress caused by excess reactive oxygen species (ROS) accelerates telomere erosion and mitochondrial in...
Aging Cell
comment
0
thumb_up
0
阅读更多
Modal title
×
Modal title
×
分享
登入
Global News and Health Forum
Join Now!
馬上登入
記住我
忘記密碼?
或者使用
Linkedin