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Obesity and Gαs Variants
Obesity and Gαs Variants
Mendes de Oliveira and colleagues now report in the Journal that variants in GNAS exons that encode the stimulatory G-prot...
Obesity-Associated GNAS Mutations and the Melanocortin Pathway
Obesity-Associated GNAS Mutations and the Melanocortin Pathway
Abstract Background GNAS encodes the Gαs (stimulatory G-protein alpha subunit) protein, which mediates G protein–coupled r...
Optogenetics — The Might of Light
Optogenetics — The Might of Light
Optogenetics Recognized through the Lasker Award This year’s Lasker Basic Medical Research Award goes to Drs. Deisseroth, ...
Breast Cancer, HER2 Mutations, and Overcoming Drug Resistance
Breast Cancer, HER2 Mutations, and Overcoming Drug Resistance
HER2-Mutated Breast Cancer and Resistance to TKI A recent study suggests that HER2-mutated breast cancer may develop resis...
Somatic PIK3CA Mutations in Sporadic Cerebral Cavernous Malformations
Somatic PIK3CA Mutations in Sporadic Cerebral Cavernous Malformations
Abstract Background Cerebral cavernous malformations (CCMs) are common sporadic and inherited vascular malformations of th...