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Delphi consensus on the diagnostic criteria of polycystic ovary syndrome
Delphi consensus on the diagnostic criteria of polycystic ovary syndrome
To gather the current opinion among Italian gynecologists and endocrinologists regarding the definition, diagnosis, and tr...
Screening of primary aldosteronism and pheochromocytoma among patients with hypertension: an Italian nationwide survey
Screening of primary aldosteronism and pheochromocytoma among patients with hypertension: an Italian nationwide survey
The delayed or missed diagnosis of secondary hypertension contributes to the poor blood pressure control worldwide. This s...
Primary ovarian insufficiency in Classic Galactosemia: a systematic review
Primary ovarian insufficiency in Classic Galactosemia: a systematic review
Galactosemia is a rare inborn error of galactose metabolism. There are several forms, the most severe being classic galact...
The thyroid hormone activating enzyme, DIO2, is a potential pan-cancer biomarker and immunotherapy target
The thyroid hormone activating enzyme, DIO2, is a potential pan-cancer biomarker and immunotherapy target
Type 2 deiodinase (D2), encoded by DIO2 gene, catalyzes the activation of the prohormone thyroxine (T4) into the bioactive...
Vitamin D supplementation in primary hyperparathyroidism: effects on 1,25(OH)2 vitamin D and FGF23 levels
Vitamin D supplementation in primary hyperparathyroidism: effects on 1,25(OH)2 vitamin D and FGF23 levels
In patients with Primary Hyperparathyroidism (PHPT) vitamin D deficiency has been associated with more severe presentation...
SP1 activates AKT3 to facilitate the development of diabetic nephropathy
SP1 activates AKT3 to facilitate the development of diabetic nephropathy
Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and has the complex pathogenesis. The previous stu...
Long noncoding RNA FAM111A-DT promotes aggressiveness of papillary thyroid cancer via activating NF-κB signaling
Long noncoding RNA FAM111A-DT promotes aggressiveness of papillary thyroid cancer via activating NF-κB signaling
Long noncoding RNAs (lncRNAs) play crucial regulatory roles in the tumorigenesis and progression of various cancers. Howev...
Emperor Leo I “the Thracian”: a possible case of Graves’ orbitopathy
Emperor Leo I “the Thracian”: a possible case of Graves’ orbitopathy
Representation of exophthalmos in ancient artworks is reported by several authors. In the present paper we analyze a sculp...
Aetiology, diagnosis and treatment of thalassemia-associated osteoporosis of the adult
Aetiology, diagnosis and treatment of thalassemia-associated osteoporosis of the adult
This review aims to overview factors contributing to TAO development and addresses the targeted diagnostic work-up and tre...
Influence of androgen receptor on bone health in transgender adults: insights from the COMET study
Influence of androgen receptor on bone health in transgender adults: insights from the COMET study
Previous studies show that transgender and gender-diverse (TGD) individuals, especially those assigned male at birth (AMAB...
Diagnostic delay, older age, and hormonal levels at diagnosis affect disease burden and mortality in acromegaly
Diagnostic delay, older age, and hormonal levels at diagnosis affect disease burden and mortality in acromegaly
Acromegaly, a rare disease with peak incidence in early adulthood, is marked by significant diagnostic delay and increased...
Insights into pubertal development: a narrative review on the role of epigenetics
Insights into pubertal development: a narrative review on the role of epigenetics
Puberty is a key phase of growth and development, characterized by psychophysical transformations. It is driven by a combi...
PCOS - the many faces of a disorder in women and men
PCOS - the many faces of a disorder in women and men
Polycystic ovary syndrome (PCOS) is a very common endocrine, metabolic and reproductive disorder. The underlying pathophys...
Performance of computer scientists in the assessment of thyroid nodules using TIRADS lexicons
Performance of computer scientists in the assessment of thyroid nodules using TIRADS lexicons
Ultrasound (US) evaluation is recognized as pivotal in assessing the risk of malignancy (RoM) of thyroid nodules (TNs). Re...
Male osteoporosis: the impact of lifestyle, from nutrition to physical activity
Male osteoporosis: the impact of lifestyle, from nutrition to physical activity
Male osteoporosis is an increasing worldwide pathological condition, characterized by an increased risk of fragility fract...
Deciphering 18F-DOPA uptake in SDH-related head and neck paragangliomas: a radiomics approach
Deciphering 18F-DOPA uptake in SDH-related head and neck paragangliomas: a radiomics approach
To investigate the influence of germline succinate dehydrogenase (SDHx) pathogenic variants on 6-[18F]-fluoro-3,4-dihydrox...
Metabolic, genetic and immunological features of relatives of type 1 diabetes patients with elevated insulin resistance
Metabolic, genetic and immunological features of relatives of type 1 diabetes patients with elevated insulin resistance
Insulin resistance plays a pivotal role in the preclinical stages of type 1 diabetes (T1D). This study aims at exploring t...
Genetics of urinary bladder paragangliomas: a multi-center study of a Chinese cohort
Genetics of urinary bladder paragangliomas: a multi-center study of a Chinese cohort
Pheochromocytomas and paragangliomas (PPGLs) exhibit the highest degree of heritability among all human tumors, yet the ge...
The immune mechanism of the mTOR/ACC1/CPT1A fatty acid oxidation signaling pathway in Hashimoto’s thyroiditis
The immune mechanism of the mTOR/ACC1/CPT1A fatty acid oxidation signaling pathway in Hashimoto’s thyroiditis
Hashimoto’s thyroiditis (HT) is the most common autoimmune thyroid disease (AITD), which is distinguished by high th...
Screening of hypercortisolism among patients with hypertension: an Italian nationwide survey
Screening of hypercortisolism among patients with hypertension: an Italian nationwide survey
Screening of Cushing Syndrome (CS) and Mild Autonomous Cortisol Secretion (MACS) in hypertensive patients is crucial for p...
Improving the radiological prediction of surgical resection of nonfunctioning pituitary adenomas
Improving the radiological prediction of surgical resection of nonfunctioning pituitary adenomas
Nonfunctioning pituitary adenomas (NFPAs) are benign tumors growing in the sellar region. Total surgical excision of the l...