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The paintings as figurative evidence of endemic goiter and cretinism in South West Piedmont in the fifteenth and sixteenth centuries
The paintings as figurative evidence of endemic goiter and cretinism in South West Piedmont in the fifteenth and sixteenth centuries
Conflict of interest The authors declare no competing interests. ...
Association between osteocalcin and residual β-cell function in children and adolescents newly diagnosed with type 1 diabetes: a pivotal study
Association between osteocalcin and residual β-cell function in children and adolescents newly diagnosed with type 1 diabetes: a pivotal study
This pivotal study aimed to evaluate circulating levels of bone remodeling markers in children and adolescents at the onse...
Inflammation-based scores in a large cohort of adrenocortical carcinoma and adrenocortical adenoma: role of the hormonal secretion pattern
Inflammation-based scores in a large cohort of adrenocortical carcinoma and adrenocortical adenoma: role of the hormonal secretion pattern
Serum inflammation-based scores can predict clinical outcome in several cancer types, including adrenocortical carcinoma (...
Taking care of inpatients with fragility hip fractures: the hip-padua osteosarcopenia (Hip-POS) fracture liaison service model
Taking care of inpatients with fragility hip fractures: the hip-padua osteosarcopenia (Hip-POS) fracture liaison service model
Osteoporotic fragility fractures (FF), particularly those affecting the hip, represent a major clinical and socio-economic...
PRDM1 promotes the ferroptosis and immune escape of thyroid cancer by regulating USP15-mediated SELENBP1 deubiquitination
PRDM1 promotes the ferroptosis and immune escape of thyroid cancer by regulating USP15-mediated SELENBP1 deubiquitination
The deubiquitinating enzyme Ubiquitin-specific peptidase 15 (USP15) is upregulated in various cancers and promotes tumor p...
Serum proteome signatures associated with liver steatosis in adolescents with obesity
Serum proteome signatures associated with liver steatosis in adolescents with obesity
Childhood obesity, a pressing global health issue, significantly increases the risk of metabolic complications, including ...
Getting old in the desired gender: a systematic review on aging diseases in transgender people
Getting old in the desired gender: a systematic review on aging diseases in transgender people
The growing demographic presence of the transgender (TGD) population has sparked an increase in clinical investigations fo...
Biochemical liver damage during gender affirming therapy in trans adults assigned female at birth: a meta-analysis
Biochemical liver damage during gender affirming therapy in trans adults assigned female at birth: a meta-analysis
To assess the effects of testosterone (T)-based gender affirming hormone therapy (GAHT) on liver blood tests (LBTs) in ass...
JPT2 in subclinical hypothyroidism-related miscarriage as a transcription co-factor: involvement of LEPR/STAT3 activation
JPT2 in subclinical hypothyroidism-related miscarriage as a transcription co-factor: involvement of LEPR/STAT3 activation
Subclinical hypothyroidism (SCH) has been identified to be associated with implantation failure, in which the dysfunction ...
Bariatric surgery modulates plasma levels of antibodies against angiotensin II type 1 and endothelin 1 type A receptor in severe obesity
Bariatric surgery modulates plasma levels of antibodies against angiotensin II type 1 and endothelin 1 type A receptor in severe obesity
The contribution of endothelial-targeted autoantibodies against the angiotensin II type 1 receptor (anti-AT1R) and the ant...
Selective anti-CXCR2 receptor blockade by AZD5069 inhibits CXCL8-mediated pro-tumorigenic activity in human thyroid cancer cells in vitro
Selective anti-CXCR2 receptor blockade by AZD5069 inhibits CXCL8-mediated pro-tumorigenic activity in human thyroid cancer cells in vitro
Thyroid cancer is the most common endocrine malignancy. Current therapies are successful, however some patients progress t...
Gut microbiota and fecal volatilome profile inspection in metabolically healthy and unhealthy obesity phenotypes
Gut microbiota and fecal volatilome profile inspection in metabolically healthy and unhealthy obesity phenotypes
People with metabolically healthy (MHO) and metabolically unhealthy obesity (MUO) differ for the presence or absence of ca...
The association between computed tomography-based osteosarcopenia and osteoporotic vertebral fractures: a longitudinal study
The association between computed tomography-based osteosarcopenia and osteoporotic vertebral fractures: a longitudinal study
Osteoporosis and sarcopenia usually coexist in older population. The concept of osteosarcopenia has been proposed in recen...
The role of body composition and appetite-regulating hormones in idiopathic central precocious puberty and their changes during GnRH analog therapy
The role of body composition and appetite-regulating hormones in idiopathic central precocious puberty and their changes during GnRH analog therapy
It was aimed to compare circulating levels of ghrelin, leptin, peptide YY (PYY), and neuropeptide (NPY) between girls with...
Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration
Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration
The use of thyroid hormones (TH) to treat obesity is unsupported by evidence as reflected in international guidelines. We ...
Molecular and functional mapping of the neuroendocrine hypothalamus: a new era begins
Molecular and functional mapping of the neuroendocrine hypothalamus: a new era begins
Recent advances in neuroscience tools for single-cell molecular profiling of brain neurons have revealed an enormous spect...
Diabetes and long duration leading to speech-, low/mid-, and high- frequency hearing loss: current evidence from the China National Health Survey 2023
Diabetes and long duration leading to speech-, low/mid-, and high- frequency hearing loss: current evidence from the China National Health Survey 2023
To examine the effect of diabetes, duration of diabetes, and blood glucose on speech-, low/mid-, and high-frequency hearin...
Changes in body composition in early breast cancer patients treated with aromatase inhibitors
Changes in body composition in early breast cancer patients treated with aromatase inhibitors
The aim of the study was to analyze the modification of total and regional body composition in early breast cancer patient...
The EPICOVID19-BS study: a web-based epidemiological survey in bariatric patients
The EPICOVID19-BS study: a web-based epidemiological survey in bariatric patients
To assess the occurrence and severity of SARS-CoV-2 infection/COVID-19, frequency of symptoms, clinical manifestations and...
Thyroid autoimmunity in different phenotypes of polycystic ovary syndrome: a single-center experience
Thyroid autoimmunity in different phenotypes of polycystic ovary syndrome: a single-center experience
Polycystic ovary syndrome (PCOS) has been associated with Hashimoto’s thyroiditis (HT) and 4 phenotypes have been de...
A novel strategy for predicting the efficacy of temozolomide treatment for metastatic pheochromocytomas/paragangliomas
A novel strategy for predicting the efficacy of temozolomide treatment for metastatic pheochromocytomas/paragangliomas
There are few studies on the efficacy of temozolomide (TMZ) in the treatment of Metastatic pheochromocytoma / paragangliom...
Endocrinology application of molecular imaging: current role of PET/CT
Endocrinology application of molecular imaging: current role of PET/CT
In recent years, nuclear medicine imaging methods have proven to be of paramount importance in a wide variety of diseases,...
Diabetes technology and sexual health: which role?
Diabetes technology and sexual health: which role?
The aim of this review is to evaluate the effects of new technology used in the management of diabetes mellitus (DM), incl...
Insights from an Italian Delphi panel: exploring resistance to first-generation somatostatin receptor ligands and guiding second-line medical therapies in acromegaly management
Insights from an Italian Delphi panel: exploring resistance to first-generation somatostatin receptor ligands and guiding second-line medical therapies in acromegaly management
First-line medical therapy for acromegaly management includes first-generation somatostatin receptor ligands (fgSRLs), but...
Smoking habits and osteoporosis in community-dwelling men subjected to dual-X-ray absorptiometry: a cross-sectional study
Smoking habits and osteoporosis in community-dwelling men subjected to dual-X-ray absorptiometry: a cross-sectional study
Active and Environmental Tobacco Smoke (ETS) are a global cause of death. Osteoporosis (Op) is the most common metabolic b...
Effect of Cabergoline on weight and glucose metabolism in patients with acromegaly
Effect of Cabergoline on weight and glucose metabolism in patients with acromegaly
Cabergoline (CAB) has shown to have benefic effects on the metabolism in different clinical settings but its metabolic rol...
Interplay of metabolic dysfunction-associated fatty liver disease and papillary thyroid carcinoma: insights from a Chinese cohort
Interplay of metabolic dysfunction-associated fatty liver disease and papillary thyroid carcinoma: insights from a Chinese cohort
Thyroid cancer is one of a set of extrahepatic cancers that closely linked to metabolic dysfunction-associated fatty liver...
A practical approach for anabolic treatment of bone fragility with romosozumab
A practical approach for anabolic treatment of bone fragility with romosozumab
Romosozumab, a fully humanized anti-sclerostin-antibody, is a bone-builder stimulating osteoblasts and inhibiting osteocla...
Impact of polygenic risk score for triglyceride trajectory and diabetic complications in subjects with type 2 diabetes based on large electronic medical record data from Taiwan: a case control study
Impact of polygenic risk score for triglyceride trajectory and diabetic complications in subjects with type 2 diabetes based on large electronic medical record data from Taiwan: a case control study
The prevalence of diabetic dyslipidemia has gradually increased worldwide and individuals with hypertriglyceridemia often ...
Infantile hypercalcemia type 1 (HCINF1): a rare disease resulting in nephrolithiasis and nephrocalcinosis caused by mutations in the vitamin D catabolic enzyme, CYP24A1
Infantile hypercalcemia type 1 (HCINF1): a rare disease resulting in nephrolithiasis and nephrocalcinosis caused by mutations in the vitamin D catabolic enzyme, CYP24A1
Infantile hypercalcemia type 1 (HCINF1), formerly known as Lightwood syndrome, is a subtype of hypercalcemia caused by los...
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