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Toll-like receptor 4 antagonists reduce cocaine-primed reinstatement of drug seeking
Toll-like receptor 4 antagonists reduce cocaine-primed reinstatement of drug seeking
Cocaine can increase inflammatory neuroimmune markers, including chemokines and cytokines characteristic of innate inflamm...
The reintroduction of hemp in the USA: a content analysis of state and tribal hemp production plans
The reintroduction of hemp in the USA: a content analysis of state and tribal hemp production plans
The reintroduction of Cannabis sativa L. in the form of hemp (< 0.3% THC by dry weight) into the US agricultu...
Besonderheiten und Probleme der Psychopharmakologie im Kindes- und Jugendalter
Besonderheiten und Probleme der Psychopharmakologie im Kindes- und Jugendalter
Die medikamentöse Behandlung von psychischen Erkrankungen im Kindes- und Jugendalter stellt eine besondere klinische ...
Fragwürdiges Akronym
Fragwürdiges Akronym
Ludwig B et al (2022) Myalgische Enzephalomyelitis/chronisches Fatigue-Syndrom: eine Übersicht zur aktuellen Evidenz. Nerv...
Characteristics of rapid cycling in 1261 bipolar disorder patients
Characteristics of rapid cycling in 1261 bipolar disorder patients
Rapid-cycling (RC; ≥ 4 episodes/year) in bipolar disorder (BD) has been recognized since the 1970s and a...
Adverse Event Profiles of Antiseizure Medications and the Impact of Coadministration on Drug Tolerability in Adults with Epilepsy
Adverse Event Profiles of Antiseizure Medications and the Impact of Coadministration on Drug Tolerability in Adults with Epilepsy
Antiseizure medication (ASM) as monotherapy or in combination is the treatment of choice for most patients with epilepsy. ...
BRAF Mutations in CNS Tumors—Prognostic Markers and Therapeutic Targets
BRAF Mutations in CNS Tumors—Prognostic Markers and Therapeutic Targets
Gliomas are a heterogeneous group of brain tumors with limited therapeutic options. However, identification of BRAF V600E ...
Psilocybin prevents reinstatement of alcohol seeking by disrupting the reconsolidation of alcohol-related memories
Psilocybin prevents reinstatement of alcohol seeking by disrupting the reconsolidation of alcohol-related memories
For most psychiatric conditions, including alcohol use disorder (AUD), FDA-approved pharmacological treatments are limited...
Choice between food and cocaine or fentanyl reinforcers under fixed and variable schedules in female and male rhesus monkeys
Choice between food and cocaine or fentanyl reinforcers under fixed and variable schedules in female and male rhesus monkeys
Illicit drugs may be unpredictable in terms of the time and effort required to obtain them, and this can be modeled with v...
Botox Use in the Older Woman: An Advanced Bladder Treatment Option
Botox Use in the Older Woman: An Advanced Bladder Treatment Option
This article focuses on challenges of caring for older women with urgency urinary incontinence (UUI), and asks how treatme...
Partial inactivation of songbird auditory cortex impairs both tempo and pitch discrimination
Partial inactivation of songbird auditory cortex impairs both tempo and pitch discrimination
Neuronal tuning for spectral and temporal features has been studied extensively in the auditory system. In the auditory co...
Opioid withdrawal: role in addiction and neural mechanisms
Opioid withdrawal: role in addiction and neural mechanisms
Withdrawal from opioids involves a negative affective state that promotes maintenance of drug-seeking behavior and relapse...
Matching-Adjusted Indirect Comparisons of Diroximel Fumarate, Ponesimod, and Teriflunomide for Relapsing Multiple Sclerosis
Matching-Adjusted Indirect Comparisons of Diroximel Fumarate, Ponesimod, and Teriflunomide for Relapsing Multiple Sclerosis
Diroximel fumarate (DRF), ponesimod (PON), and teriflunomide (TERI) are oral disease-modifying therapies approved for the ...
Implementation and workflow strategies for integrating digital therapeutics for alcohol use disorders into primary care: a qualitative study
Implementation and workflow strategies for integrating digital therapeutics for alcohol use disorders into primary care: a qualitative study
Alcohol use disorders (AUD) are prevalent and often go untreated. Patients are commonly screened for AUD in primary care, ...
Prevalence and risk factors of burden among caregivers of older emergency department patients
Prevalence and risk factors of burden among caregivers of older emergency department patients
The number of older individuals that live independently at home is rising. These older individuals often rely on caregiver...
Item Understanding of Common Quality of Life Measures for use with Autistic Adults
Item Understanding of Common Quality of Life Measures for use with Autistic Adults
Quality of life (QOL) and life satisfaction are important research priorities for autistic adults. As such, we saw a need ...
Exploring Evidence for Mindfulness and Subjective Wellbeing Homeostatic Resilience Buffering Depression and Stress Symptoms Associated with Inflammatory Bowel Disease
Exploring Evidence for Mindfulness and Subjective Wellbeing Homeostatic Resilience Buffering Depression and Stress Symptoms Associated with Inflammatory Bowel Disease
People with inflammatory bowel disease (IBD) are known to experience high levels of psychological symptoms, associated wit...
Motor-kognitives Risikosyndrom – Weichenstellung für die Demenzprävention?
Motor-kognitives Risikosyndrom – Weichenstellung für die Demenzprävention?
Der prognostizierte starke Anstieg demenzieller Erkrankungen wird auch das deutsche Gesundheitssystem vor große Herau...
Postoperatives Management nach dekompressiver Hemikraniektomie bei malignem Mediainfarkt – eine deutschlandweite Umfragestudie
Postoperatives Management nach dekompressiver Hemikraniektomie bei malignem Mediainfarkt – eine deutschlandweite Umfragestudie
Der maligne Mediainfarkt ist ein potenziell lebensbedrohliches Krankheitsbild. Die dekompressive Hemikraniektomie gehö...
Correction to: Inhibition of mGluR5 alters BDNF/TrkB and GLT‑1 expression in the prefrontal cortex and hippocampus and ameliorates PTSD‑like behavior in rats
Correction to: Inhibition of mGluR5 alters BDNF/TrkB and GLT‑1 expression in the prefrontal cortex and hippocampus and ameliorates PTSD‑like behavior in rats
Department of Medical Psychology and Ethics, School of Basic Medical Medicine Sciences, Cheeloo College of Medicine, Shand...
Liraglutide attenuates nicotine self-administration as well as nicotine seeking and hyperphagia during withdrawal in male and female rats
Liraglutide attenuates nicotine self-administration as well as nicotine seeking and hyperphagia during withdrawal in male and female rats
Nicotine cessation is associated with increased consumption of highly palatable foods and body weight gain in most smokers...
Psychotherapie bei Störungen der Intelligenzentwicklung – aktuelle Evidenz und praktische Umsetzung
Psychotherapie bei Störungen der Intelligenzentwicklung – aktuelle Evidenz und praktische Umsetzung
Menschen mit einer Störung der Intelligenzentwicklung (deutsche Entwurfsfassung der ICD-11, in Kraft getreten am 01.0...
Andexanet Alfa to Reverse the Effect of Factor Xa Inhibitors in Intracranial Hemorrhage
Andexanet Alfa to Reverse the Effect of Factor Xa Inhibitors in Intracranial Hemorrhage
Andexanet alfa (AA) is a recombinant factor Xa competing for binding with factor Xa inhibitors, thereby reversing...
Disentangling between- and within-person alcohol and expectancy effects on acute alcohol craving
Disentangling between- and within-person alcohol and expectancy effects on acute alcohol craving
Alcohol craving is a predictor of continued drinking and a diagnostic criterion for alcohol use disorder. Rewarding subjec...
The comparative effectiveness of metformin and risperidone in a rat model of valproic acid-induced autism, Potential role for enhanced autophagy
The comparative effectiveness of metformin and risperidone in a rat model of valproic acid-induced autism, Potential role for enhanced autophagy
Risperidone is the first antipsychotic to be approved by Food and Drug Administration (FDA) for treating autism spectrum d...
A novel micro-ECoG recording method for recording multisensory neural activity from the parietal to temporal cortices in mice
A novel micro-ECoG recording method for recording multisensory neural activity from the parietal to temporal cortices in mice
Characterization of inter-regional interactions in brain is essential for understanding the mechanism relevant to normal b...
Erwartungen der Leitlinienentwickler*innen an „living guidelines“
Erwartungen der Leitlinienentwickler*innen an „living guidelines“
Leitlinien stellen zentrale Pfeiler einer qualitativ hochwertigen Versorgung und Versorgungsplanung dar. Die Qualität...
COVID-19-Impfung für Menschen mit schweren psychischen Erkrankungen
COVID-19-Impfung für Menschen mit schweren psychischen Erkrankungen
Schwere psychische Erkrankungen sind Risikofaktoren für SARS-CoV-2-bezogene Morbidität und Mortalität. Impf...
Effects of chronic methamphetamine exposure on rewarding behavior and neurodegeneration markers in adult mice
Effects of chronic methamphetamine exposure on rewarding behavior and neurodegeneration markers in adult mice
Recreational and medical use of stimulants among young adults have gained popularity in the United States over the last de...
Prefrontal allopregnanolone synergizes with D1 receptor activation to disrupt sensorimotor gating in male Sprague-Dawley rats
Prefrontal allopregnanolone synergizes with D1 receptor activation to disrupt sensorimotor gating in male Sprague-Dawley rats
The prepulse inhibition (PPI) of the startle reflex is the best-established index of sensorimotor gating. We documented th...
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