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Myeloid cell iron uptake pathways and paramagnetic rim formation in multiple sclerosis
Myeloid cell iron uptake pathways and paramagnetic rim formation in multiple sclerosis
In multiple sclerosis (MS), sustained inflammatory activity can be visualized by iron-sensitive magnetic resonance imaging...
The choroidal nervous system: a link between mineralocorticoid receptor and pachychoroid
The choroidal nervous system: a link between mineralocorticoid receptor and pachychoroid
Central serous chorioretinopathy (CSCR) belongs to the pachychoroid spectrum, a pathological phenotype of the choroidal va...
Microglial contribution to the pathology of neurodevelopmental disorders in humans
Microglial contribution to the pathology of neurodevelopmental disorders in humans
Microglia are the brain’s resident macrophages, which guide various developmental processes crucial for brain matura...
Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma
Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma
Pilocytic astrocytoma (PA), the most common pediatric brain tumor, is driven by aberrant mitogen-activated protein kinase ...
Analysis of inflammatory markers and tau deposits in an autopsy series of nine patients with anti-IgLON5 disease
Analysis of inflammatory markers and tau deposits in an autopsy series of nine patients with anti-IgLON5 disease
Anti-IgLON5 disease is a rare neurological, probably autoimmune, disorder associated in many cases with a specific tauopat...
Detection of blood–brain barrier disruption in brains of patients with COVID-19, but no evidence of brain penetration by SARS-CoV-2
Detection of blood–brain barrier disruption in brains of patients with COVID-19, but no evidence of brain penetration by SARS-CoV-2
Hay JR, Johnson VE, Young AM, Smith DH, Stewart W (2015) Blood-Brain Barrier Disruption Is an Early Event That May Persist...
Correction: APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer’s disease
Correction: APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer’s disease
Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, Perelman School of Medi...
Neuronal tau pathology worsens late-phase white matter degeneration after traumatic brain injury in transgenic mice
Neuronal tau pathology worsens late-phase white matter degeneration after traumatic brain injury in transgenic mice
Traumatic brain injury (TBI) causes diffuse axonal injury which can produce chronic white matter pathology and subsequent ...
The variance in phosphorylated, insoluble ⍺-synuclein in humans, rats, and mice is not mainly driven by biological sex
The variance in phosphorylated, insoluble ⍺-synuclein in humans, rats, and mice is not mainly driven by biological sex
Attems J, Toledo JB, Walker L, Gelpi E, Gentleman S, Halliday G et al (2021) Neuropathological consensus criteria for the ...
TDP-43 differentially propagates to induce antero- and retrograde degeneration in the corticospinal circuits in mouse focal ALS models
TDP-43 differentially propagates to induce antero- and retrograde degeneration in the corticospinal circuits in mouse focal ALS models
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by TDP-43 inclusions in the c...
Inflammation and the pathological progression of Alzheimer’s disease are associated with low circulating choline levels
Inflammation and the pathological progression of Alzheimer’s disease are associated with low circulating choline levels
Deficiency of dietary choline, an essential nutrient, is observed worldwide, with ~ 90% of Americans being ...
Correction to: Intraneuronal aggregation of the β‑CTF fragment of APP (C99) induces Aβ‑independent lysosomal-autophagic pathology
Correction to: Intraneuronal aggregation of the β‑CTF fragment of APP (C99) induces Aβ‑independent lysosomal-autophagic pathology
Cite this articleLauritzen, I., Pardossi‑Piquard, R., Bourgeois, A. et al. Correction to: Intraneuronal aggregation of the...
DNA-methylation subgroups carry no prognostic significance in ATRT-SHH patients in clinical trial cohorts
DNA-methylation subgroups carry no prognostic significance in ATRT-SHH patients in clinical trial cohorts
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse high-grade gliomas, CNS WHO grade 4
A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse high-grade gliomas, CNS WHO grade 4
Malignant brain tumors, known as H3K27-altered diffuse midline glioma (DMG) and H3G34-mutant diffuse hemispheric glioma (D...
Integrated genetic analyses of immunodeficiency-associated Epstein-Barr virus- (EBV) positive primary CNS lymphomas
Integrated genetic analyses of immunodeficiency-associated Epstein-Barr virus- (EBV) positive primary CNS lymphomas
Immunodeficiency-associated primary CNS lymphoma (PCNSL) represents a distinct clinicopathological entity, which is typica...
Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS
Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease mainly affecting upper and lower motoneurons. Sev...
More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy
More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy
The accumulation of proteinaceous inclusions in the brain is a common feature among neurodegenerative diseases such as Alz...
A T-cell antigen atlas for meningioma: novel options for immunotherapy
A T-cell antigen atlas for meningioma: novel options for immunotherapy
Meningiomas are the most common primary intracranial tumors. Although most symptomatic cases can be managed by surgery and...
SMN regulates GEMIN5 expression and acts as a modifier of GEMIN5-mediated neurodegeneration
SMN regulates GEMIN5 expression and acts as a modifier of GEMIN5-mediated neurodegeneration
GEMIN5 is essential for core assembly of small nuclear Ribonucleoproteins (snRNPs), the building blocks of spliceosome for...
Mutation ∆K281 in MAPT causes Pick’s disease
Mutation ∆K281 in MAPT causes Pick’s disease
Two siblings with deletion mutation ∆K281 in MAPT developed frontotemporal dementia. At autopsy, numerous i...
Cell-specific MAPT gene expression is preserved in neuronal and glial tau cytopathologies in progressive supranuclear palsy
Cell-specific MAPT gene expression is preserved in neuronal and glial tau cytopathologies in progressive supranuclear palsy
Microtubule-associated protein tau (MAPT) aggregates in neurons, astrocytes and oligodendrocytes in a number of neurodegen...