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Correction: Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N-truncted Abeta in sporadic Alzheimer disease cases and mouse models
Under the heading “Material and Methods section at page 716”, the text was incorrectl...
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Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice
TMEM106B, a gene encoding a lysosome membrane protein, is tightly associated with brain aging, hypomyelinating leukodystro...
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A muscarinic receptor antagonist reverses multiple indices of diabetic peripheral neuropathy: preclinical and clinical studies using oxybutynin
Preclinical studies indicate that diverse muscarinic receptor antagonists, acting via the M1 sub-type, promote neuritogene...
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TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy
TMEM106B is a risk modifier of multiple neurological conditions, where a single coding variant and multiple non-coding SNP...
Acta Neuropathologica
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Disentangling and quantifying the relative cognitive impact of concurrent mixed neurodegenerative pathologies
Neurodegenerative pathologies such as Alzheimer disease neuropathologic change (ADNC), Lewy body disease (LBD), limbic-pre...
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Gene transcript fusions are associated with clinical outcomes and molecular groups of meningiomas
Agnihotri S, Suppiah S, Tonge PD, Jalali S, Danesh A, Bruce JP et al (2017) Therapeutic radiation for childhood cancer dri...
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MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons
Inclusions comprised of microtubule-associated protein tau (tau) are implicated in a group of neurodegenerative diseases, ...
Acta Neuropathologica
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Role of GBA variants in Lewy body disease neuropathology
Rare and common GBA variants are risk factors for both Parkinson’s disease (PD) and dementia with Lewy bodies (DLB)....
Acta Neuropathologica
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Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia
The stimulator of interferon genes (STING) pathway has been implicated in neurodegenerative diseases, including Parkinson&...
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The prevalence and topography of spinal cord demyelination in multiple sclerosis: a retrospective study
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Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease
Parkinson’s disease (PD) starts at the molecular and cellular level long before motor symptoms appear, yet there are...
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Alteration of LARGE1 abundance in patients and a mouse model of 5q-associated spinal muscular atrophy
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Methylation class oligosarcoma, IDH-mutant could exhibit astrocytoma-like molecular features
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RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS
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Disruption of the blood–brain barrier is correlated with spike endocytosis by ACE2 + endothelia in the CNS microvasculature in fatal COVID-19. Scientific commentary on "Detection of blood–brain barrier disruption in brains of patients with COVID-19, but no evidence of brain penetration by SARS-CoV-2”
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Myofiber-type-dependent ‘boulder’ or ‘multitudinous pebble’ formations across distinct amylopectinoses
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Astroglial calcium signaling and homeostasis in tuberous sclerosis complex
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Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE
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MET receptor serves as a promising target in melanoma brain metastases
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Aggressive human MenG C meningiomas have a molecular counterpart in canines
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Canine meningiomas are comprised of 3 DNA methylation groups that resemble the molecular characteristics of human meningiomas
Abyzov A, Urban AE, Snyder M, Gerstein M (2011) CNVnator: an approach to discover, genotype, and characterize typical and ...
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PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease which currently lacks effective treatments. Mutat...
Acta Neuropathologica
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Regional AT-8 reactive tau species correlate with intracellular Aβ levels in cases of low AD neuropathologic change
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The niche matters: origin, function and fate of CNS-associated macrophages during health and disease
There are several cellular and acellular structural barriers associated with the brain interfaces, which include the dura,...
Acta Neuropathologica
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The contribution of β-amyloid, Tau and α-synuclein to blood–brain barrier damage in neurodegenerative disorders
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Acta Neuropathologica
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Endothelial cells and macrophages as allies in the healthy and diseased brain
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Pineal parenchymal tumors of intermediate differentiation: in need of a stringent definition to avoid confusion. Scientific commentary on ‘Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics’
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Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease
Synapse loss correlates with cognitive decline in Alzheimer’s disease, and soluble oligomeric amyloid beta (Aβ)...
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“RYR1 and the cerebellum”: scientific commentary on “Defective Cerebellar Ryanodine Receptor Type 1 and Endoplasmic Reticulum Calcium ‘Leak’ in Tremor Pathophysiology”
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
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Neuroinflammatory disease signatures in SPG11-related hereditary spastic paraplegia patients
Biallelic loss of SPG11 function constitutes the most frequent cause of complicated autosomal recessive hereditary spastic...
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