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NEDD8 enhances Hippo signaling by mediating YAP1 neddylation
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Escherichia coli monothiol glutaredoxin GrxD replenishes Fe-S clusters to the essential ErpA A-type carrier under low iron stress
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Intact and mutated Shigella diguanylate cyclases increase c-di-GMP
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TORC2 is required for the accumulation of γH2A in response to DNA damage
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Inhibition of BACE1 affected both its Aβ producing and degrading activities and increased Aβ42 and Aβ40 levels at high-level BACE1 expression
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Identification and biophysical characterization of a novel domain-swapped camelid antibody specific for fentanyl
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An alcove at the acetyl-CoA synthase nickel active site is required for productive substrate CO binding and anaerobic carbon fixation
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Shy is a proteobacterial steroid hydratase which catalyzes steroid side chain degradation without requiring a catalytically inert partner domain
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Gene regulation in regeneration after acute kidney injury
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A fluorescence polarization assay for high-throughput screening of inhibitors against HIV-1 Nef-mediated MHC-I downregulation
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Lack of mismatch repair enhances resistance to methylating agents for cells deficient in oxidative demethylation
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ErbB3 is required for hyperaminoacidemia-induced pancreatic α cell hyperplasia
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Acetylation of WCC is dispensable for the core circadian clock but differentially regulates acute light responses in Neurospora
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Drug metabolism of ciprofloxacin, ivacaftor, and raloxifene by Pseudomonas aeruginosa cytochrome P450 CYP107S1
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Isoform balance of the long noncoding RNA NEAT1 is regulated by the RNA-binding protein QKI, governs the glioma transcriptome, and impacts cell migration
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In vitro reconstitution of transition metal transporters
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Intermediate steps in the formation of neuronal SNARE complexes
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Action and cooperation in alginate degradation by three enzymes from the human gut bacterium Bacteroides eggerthii DSM 20697
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Hydroxysteroid 17-β dehydrogenase 14 (HSD17B14) is an L-fucose dehydrogenase, the initial enzyme of the L-fucose degradation pathway
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Structural and thermodynamic characterization of a highly amyloidogenic dimer of transthyretin involved in a severe cardiomyopathy
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iMSC exosome delivers hsa-mir-125b-5p and strengthens acidosis resilience through suppression of Asic1 protein in cerebral ischemia-reperfusion
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Her4.3+ radial glial cells maintain the brain vascular network through activation of Wnt signaling
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Different roles of the heterodimer architecture of galectin-4 in selective recognition of oligosaccharides and lipopolysaccharides having ABH antigens
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Ferroptosis regulation by Cap’n’collar family transcription factors
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Ccr4-Not ubiquitin ligase signaling regulates ribosomal protein homeostasis and inhibits 40S ribosomal autophagy
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Molecular characterization of Rft1, an ER membrane protein associated with congenital disorder of glycosylation RFT1-CDG
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A pre-B acute lymphoblastic leukemia cell line model reveals the mechanism of thalidomide therapy related B-cell leukemogenesis
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Structural insights into rice KAI2 receptor provide functional implications for perception and signal transduction
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Novel Z-DNA binding domains in giant viruses
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Defining a chromatin architecture that supports transcription at RNA polymerase II promoters
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