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Revealing novel and conservative T-cell epitopes with MHC B2 restriction on H9N2 Avian Influenza Virus (AIV)
Revealing novel and conservative T-cell epitopes with MHC B2 restriction on H9N2 Avian Influenza Virus (AIV)
Author links open overlay panel, , , , , , , , , , ABSTRACTB2 haplotype MHC has been extensively reported to confer resist...
PTIP UFMylation promotes replication fork degradation in BRCA1-deficient cells
PTIP UFMylation promotes replication fork degradation in BRCA1-deficient cells
Journal of Biological ChemistryVolume 300, Issue 6, June 2024, 107312Author links open overlay panel, Homologous-recombina...
The types and numbers of kinesins and dyneins transporting endocytic cargoes modulate their motility and response to tau
The types and numbers of kinesins and dyneins transporting endocytic cargoes modulate their motility and response to tau
Keywordstau protein (tau)microtubule-associated protein (MAP)kinesindyneinorganelle transportin vitro reconstitutionoptica...
A minimum functional form of the Escherichia coli BAM complex constituted by BamADE assembles outer membrane proteins in vitro
A minimum functional form of the Escherichia coli BAM complex constituted by BamADE assembles outer membrane proteins in vitro
Keywordsβ-barrel assembly machinery (BAM)outer membrane proteinsin vitro reconstitutionprotein integrationmembrane protein...
Testis Specific Serine Kinase 6 (TSSK6) is abnormally expressed in colorectal cancer and promotes oncogenic behaviors
Testis Specific Serine Kinase 6 (TSSK6) is abnormally expressed in colorectal cancer and promotes oncogenic behaviors
Author links open overlay panel, , , , , AbstractCancer testis antigens (CTAs) are a collection of proteins whose expressi...
Novel markers of MCL1 inhibitor sensitivity in triple negative breast cancer cells
Novel markers of MCL1 inhibitor sensitivity in triple negative breast cancer cells
Triple negative breast cancer (TNBC) is an aggressive breast cancer sub-type with limited treatment options and poor progn...
The binding of LARP6 and DNAAF6 in biomolecular condensates influences ciliogenesis of multi-ciliated cells
The binding of LARP6 and DNAAF6 in biomolecular condensates influences ciliogenesis of multi-ciliated cells
Author links open overlay panel, , , , , , , , , , AbstractMotile cilia on the cell surface produce fluid flows in the bod...
ZNT5-6 and ZNT7 play an integral role in protein N-glycosylation by supplying Zn2+ to Golgi α-mannosidase II
ZNT5-6 and ZNT7 play an integral role in protein N-glycosylation by supplying Zn2+ to Golgi α-mannosidase II
Zn2+N-glycosylationtransporterGolgi mannosidase II (GMII)lysosomal mannosidase (LAMAN)ZNTearly secretory compartmentspancr...
CK2-HTATSF1-TOPBP1 signaling axis modulates tumor chemotherapy response
CK2-HTATSF1-TOPBP1 signaling axis modulates tumor chemotherapy response
Author links open overlay panel, , , , , , , , , AbstractHomologous recombination (HR) plays a key role in maintaining gen...
Transient kinetics reveal the mechanism of competitive inhibition of the neutral amino acid transporter ASCT2
Transient kinetics reveal the mechanism of competitive inhibition of the neutral amino acid transporter ASCT2
KeywordsNeutral amino acid transporterASCT2electrophysiologykineticsrapid solution exchangemembrane proteininhibition mech...
Classical and non-classical effects of angiotensin converting enzyme: how increased ACE enhances myeloid immune function.
Classical and non-classical effects of angiotensin converting enzyme: how increased ACE enhances myeloid immune function.
As part of the classical renin-angiotensin system, the peptidase angiotensin converting enzyme (ACE) makes angiotensin II ...
Post-translational control of NLRP3 inflammasome signaling
Post-translational control of NLRP3 inflammasome signaling
Inflammasomes serve as critical sensors for disruptions to cellular homeostasis, with inflammasome assembly leading to inf...
An active site mutation induces oxygen reactivity in D-arginine dehydrogenase: A case of superoxide diverting protons †
An active site mutation induces oxygen reactivity in D-arginine dehydrogenase: A case of superoxide diverting protons †
KeywordsPseudomonas aeruginosa D-arginine dehydrogenasepH profilesnon-stoichiometric slopesuperoxidesuperoxide disproporti...
Consensus, controversies, and conundrums of P4-ATPases: the emerging face of eukaryotic lipid flippases
Consensus, controversies, and conundrums of P4-ATPases: the emerging face of eukaryotic lipid flippases
Author links open overlay panel, AbstractThe cryo-EM resolution revolution has heralded a new era in our understanding of ...
Pan-cancer analysis of telomere maintenance mechanisms
Pan-cancer analysis of telomere maintenance mechanisms
Keywordscancertelomeretelomere maintenance mechanismstelomerasealternative lengthening of telomerespathway signal flowAbbr...
Kaempferol attenuates particle-induced osteogenic impairment by regulating ER stress via the IRE1α/XBP1s pathway
Kaempferol attenuates particle-induced osteogenic impairment by regulating ER stress via the IRE1α/XBP1s pathway
Author links open overlay panel, , , , , , , , , , , , , , AbstractPeriprosthetic osteolysis and subsequent aseptic loosen...
Immunoglobulin constant regions provide stabilization to the paratope and enforce epitope specificity.
Immunoglobulin constant regions provide stabilization to the paratope and enforce epitope specificity.
Constant domains in antibody molecules at the level of the Fab (CH1 and CL) have long been considered to be simple scaffol...
Reactivating Hippo by drug compounds to suppress gastric cancer and enhance chemotherapy sensitivity
Reactivating Hippo by drug compounds to suppress gastric cancer and enhance chemotherapy sensitivity
Journal of Biological ChemistryVolume 300, Issue 6, June 2024, 107311Author links open overlay panel, , , , , , , , , , , ...
S100A4 makes two appearances in mechanisms leading to fibrosis
S100A4 makes two appearances in mechanisms leading to fibrosis
Author links open overlay panelNon-muscle myosin 2 (NM2) is known to play an important role in myofibroblast transdifferen...
The increase of long noncoding RNA Fendrr in hepatocytes contributes to liver fibrosis by promoting IL-6 production
The increase of long noncoding RNA Fendrr in hepatocytes contributes to liver fibrosis by promoting IL-6 production
Author links open overlay panel, , , , , , , , , AbstractLiver fibrosis/cirrhosis is a pathological state caused by excess...
Bacterial cysteate dissimilatory pathway involves a racemase and D-cysteate sulfo-lyase
Bacterial cysteate dissimilatory pathway involves a racemase and D-cysteate sulfo-lyase
Keywordscysteatesulfo-lyaseracemaseBilophila wadsworthia, terminal electron acceptorAbbreviationsPLPpyridoxal 5′-phosphate...
Polymerization mechanism of the Candida albicans virulence factor candidalysin
Polymerization mechanism of the Candida albicans virulence factor candidalysin
Author links open overlay panel, , , , , AbstractCandida albicans is a commensal fungus that can cause epithelial infectio...
Cardioprotective properties of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids
Cardioprotective properties of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids
Author links open overlay panel, , , , , , ABSTRACTOMT-28 is a metabolically robust small molecule developed to mimic the ...