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Management of Patients with Early Myelofibrosis: A Discussion of Best Practices
Management of Patients with Early Myelofibrosis: A Discussion of Best Practices
Summarize best practices for management of patients with early myelofibrosis (MF). Myelofibrosis is a progressive myelopro...
Telomere Biology Disorder: A Focus on Gastrointestinal and Hepatic Manifestations
Telomere Biology Disorder: A Focus on Gastrointestinal and Hepatic Manifestations
Telomere biology disorders (TBD) encompass several illnesses caused by underlying mutations in telomere maintenance leadin...
Transplantation and Cellular Therapy for Older Adults—The MSK Approach
Transplantation and Cellular Therapy for Older Adults—The MSK Approach
Hematologic malignances more commonly affect older individuals and often present with advanced, higher risk disease than y...
Frontline Therapy of CLL—Changing Treatment Paradigms
Frontline Therapy of CLL—Changing Treatment Paradigms
The therapeutic landscape for chronic lymphocytic leukemia (CLL) has undergone a complete makeover following the introduct...
How Do We Manage Chronic Lymphocytic Leukemia in India
How Do We Manage Chronic Lymphocytic Leukemia in India
Chronic lymphocytic leukemia was an ignored leukemia in India until a decade back, given its low prevalence and absence of...
Treatment of Richter’s Transformation with Novel Therapies
Treatment of Richter’s Transformation with Novel Therapies
This review presents recently published clinical trial data and ongoing investigations regarding the treatment of Richter&...
Diagnosis and Management of Pulmonary Manifestations of Telomere Biology Disorders
Diagnosis and Management of Pulmonary Manifestations of Telomere Biology Disorders
Telomere biology disorders (TBD) are a group of genetic disorders characterized by premature shortening of telomeres, resu...
Adaptive and Maladaptive Clonal Hematopoiesis in Telomere Biology Disorders
Adaptive and Maladaptive Clonal Hematopoiesis in Telomere Biology Disorders
Telomere biology disorders (TBDs) are germline-inherited conditions characterized by reduction in telomerase function, acc...
Blinatumomab in Practice
Blinatumomab in Practice
Acute lymphoblastic leukemia (ALL) is a rare hematologic neoplasm in adults, with most cases defined by pathology related ...
Novel Biomarkers and Molecular Targets in ALL
Novel Biomarkers and Molecular Targets in ALL
Acute lymphoblastic leukemia (ALL) is a widely heterogeneous disease in terms of genomic alterations, treatment options, a...
Unlocking the Potential of Artificial Intelligence in Acute Myeloid Leukemia and Myelodysplastic Syndromes
Unlocking the Potential of Artificial Intelligence in Acute Myeloid Leukemia and Myelodysplastic Syndromes
This review aims to elucidate the transformative impact and potential of machine learning (ML) in the diagnosis, prognosis...
Measurable Residual Disease Monitoring in Lymphoma
Measurable Residual Disease Monitoring in Lymphoma
The utility of analyzing circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), and disease in the bone marrow as ...
Experimental and Computational Approaches to Measure Telomere Length: Recent Advances and Future Directions
Experimental and Computational Approaches to Measure Telomere Length: Recent Advances and Future Directions
The length of telomeres, protective structures at the chromosome ends, is a well-established biomarker for pathological co...
Updates in the Classification of T-cell Lymphomas and Lymphoproliferative Disorders
Updates in the Classification of T-cell Lymphomas and Lymphoproliferative Disorders
Mature T/NK-cell neoplasms comprise a heterogeneous group of diseases with diverse clinical, histopathologic, immunophenot...
Genetic Counseling and Family Screening Recommendations in Patients with Telomere Biology Disorders
Genetic Counseling and Family Screening Recommendations in Patients with Telomere Biology Disorders
Telomere biology disorders (TBDs) encompass a spectrum of genetic diseases with a common pathogenesis of defects in telome...
NK Cell Therapeutics for Hematologic Malignancies: from Potential to Fruition
NK Cell Therapeutics for Hematologic Malignancies: from Potential to Fruition
The current review focuses on the preclinical development and clinical advances of natural killer (NK) cell therapeutics f...
An Update on the Management of Advanced Phase Chronic Myeloid Leukemia
An Update on the Management of Advanced Phase Chronic Myeloid Leukemia
While most patients with chronic myeloid leukemia (CML) present in a chronic phase and are expected to have a normal life ...
Central Nervous System Relapse in T and NK cell Lymphomas
Central Nervous System Relapse in T and NK cell Lymphomas
T and NK cell lymphomas are relatively rare and heterogeneous forms of non-Hodgkin lymphoma that are associated with high ...
EBV Reactivation and Lymphomagenesis: More Questions than Answers
EBV Reactivation and Lymphomagenesis: More Questions than Answers
Epstein-Barr Virus (EBV) is a ubiquitous herpesvirus that affects almost all humans and establishes lifelong infections by...
Developing Targeted Therapies for T Cell Acute Lymphoblastic Leukemia/Lymphoma
Developing Targeted Therapies for T Cell Acute Lymphoblastic Leukemia/Lymphoma
Largely, treatment advances in relapsed and/or refractory acute lymphoblastic leukemia (ALL) have been made in B cell dise...
Financial Toxicity in Patients with Hematologic Malignancies: a Review and Need for Interventions
Financial Toxicity in Patients with Hematologic Malignancies: a Review and Need for Interventions
Financial toxicity is a developing research area to quantify the financial stress experienced by patients and caregivers, ...
Multiple Myeloma: Current Clinical Landscape and Compounding Costs
Multiple Myeloma: Current Clinical Landscape and Compounding Costs
The treatment landscape of multiple myeloma (MM) has evolved resulting in MM becoming a chronic condition. The costs of MM...
Real-world Management of CML: Outcomes and Treatment Patterns
Real-world Management of CML: Outcomes and Treatment Patterns
Chronic myeloid leukemia (CML) is a disease that previously signified a poor prognosis, but treatment options and outcomes...
A Journey Through JAK Inhibitors for the Treatment of Myeloproliferative Diseases
A Journey Through JAK Inhibitors for the Treatment of Myeloproliferative Diseases
Chronic myeloproliferative neoplasms (MPN) represent a group of diseases characterised by constitutive activation of the J...
Response-Adapted Therapy for Newly Diagnosed Multiple Myeloma
Response-Adapted Therapy for Newly Diagnosed Multiple Myeloma
The development of potent novel agents has improved outcomes for patients with multiple myeloma (MM). Heterogeneity of res...
Richter Transformation of Chronic Lymphocytic Leukemia—Are We Making Progress?
Richter Transformation of Chronic Lymphocytic Leukemia—Are We Making Progress?
The treatment paradigm of chronic lymphocytic leukemia (CLL) has dramatically changed with the advent of novel targeted ag...
Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)
Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)
There have been significant advances in the treatment of relapsed/refractory chronic lymphocytic leukemia (CLL) over the p...
Sporadic and Familial Acute Myeloid Leukemia with CEBPA Mutations
Sporadic and Familial Acute Myeloid Leukemia with CEBPA Mutations
CCAAT enhancer binding protein A (CEBPA) gene mutation is one of the common genetic alterations in acute myeloid leukemia ...
GATA2 Deficiency: Predisposition to Myeloid Malignancy and Hematopoietic Cell Transplantation
GATA2 Deficiency: Predisposition to Myeloid Malignancy and Hematopoietic Cell Transplantation
GATA2 deficiency is a haploinsufficiency syndrome associated with a wide spectrum of disease, including severe monocytopen...
Clonal Hematopoiesis in Myeloproliferative Neoplasms Confers a Predisposition to both Thrombosis and Cancer
Clonal Hematopoiesis in Myeloproliferative Neoplasms Confers a Predisposition to both Thrombosis and Cancer
This review focuses on vascular complications associated with chronic myeloproliferative neoplasms (MPN) and more specific...