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The methyl-CpG-binding domain 2 facilitates pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation
The methyl-CpG-binding domain 2 facilitates pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation
IntroductionIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fibrotic lung disease, usually leading to de...
New insights into methylome alterations and consequences during myofibroblastic differentiation in pulmonary fibrosis
New insights into methylome alterations and consequences during myofibroblastic differentiation in pulmonary fibrosis
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Moving the dial on identifying endotypes of asthma from early life
Moving the dial on identifying endotypes of asthma from early life
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T2-high asthma phenotypes across lifespan
T2-high asthma phenotypes across lifespan
Study group: Oliver Fuchs (Department of Paediatric Allergology, Dr von Hauner Children's Hospital, Ludwig Maximilians Uni...
Is bronchopulmonary dysplasia in adult age a novel COPD endotype?
Is bronchopulmonary dysplasia in adult age a novel COPD endotype?
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Increased cytotoxic T-cells in the airways of adults with former bronchopulmonary dysplasia
Increased cytotoxic T-cells in the airways of adults with former bronchopulmonary dysplasia
IntroductionBronchopulmonary dysplasia (BPD) is a common cause of respiratory insufficiency in children born very to extre...
Case-finding and diagnosis of obstructive airway diseases: the Dragons Den experience
Case-finding and diagnosis of obstructive airway diseases: the Dragons Den experience
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Effect of marijuana smoking on lung function change in older ever tobacco smokers
Effect of marijuana smoking on lung function change in older ever tobacco smokers
The authors thank the SPIROMICS participants and participating physicians, investigators, and staff for making this resear...
Differentiating COPD and asthma using quantitative CT imaging and machine learning
Differentiating COPD and asthma using quantitative CT imaging and machine learning
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The burden of asthma, hay fever and eczema in adults in 17 countries: GAN Phase I study
The burden of asthma, hay fever and eczema in adults in 17 countries: GAN Phase I study
This article has an editorial commentary: https://doi.org/10.1183/13993003.00440-2022Global Asthma Network Study Group. Gl...
The burden of asthma, hay fever and eczema in children in 25 countries: GAN Phase I study
The burden of asthma, hay fever and eczema in children in 25 countries: GAN Phase I study
DiscussionAlthough with considerable variations at centre, country and GNI levels, the overall global burden of asthma, rh...
Low-dose oral corticosteroids in asthma associates with increased morbidity and mortality
Low-dose oral corticosteroids in asthma associates with increased morbidity and mortality
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COVID-19 follow-up programmes across Europe: an ERS END-COVID CRC survey
COVID-19 follow-up programmes across Europe: an ERS END-COVID CRC survey
To the Editor:SARS-CoV-2 is responsible for a multi-organ syndrome that can last over 12 months after the initial infectio...
Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes
Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes
Members of the DZIF-TB cohort study group: Jan Heyckendorf (Division of Clinical Infectious Diseases, Research Center Bors...
COMPERA 2.0 risk stratification in medically managed chronic thromboembolic pulmonary hypertension
COMPERA 2.0 risk stratification in medically managed chronic thromboembolic pulmonary hypertension
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COVID-19 drug research and the cohort multiple randomised controlled trial design
COVID-19 drug research and the cohort multiple randomised controlled trial design
To the Editor:Soon after the start of the coronavirus disease 2019 (COVID-19) pandemic, in May 2020, more than 1300 trials...
Planetary respiratory health for asthma, rhinoconjunctivitis and eczema
Planetary respiratory health for asthma, rhinoconjunctivitis and eczema
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Risk assessment of systemic sclerosis-associated pulmonary arterial hypertension: cardiac index versus stroke volume index
Risk assessment of systemic sclerosis-associated pulmonary arterial hypertension: cardiac index versus stroke volume index
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Oral corticosteroids in asthma and beyond: moving forward
Oral corticosteroids in asthma and beyond: moving forward
Conflict of interest: J.S.K. Chan and R.B. Murray report no conflicts of interest. D. Price reports advisory board members...
Impact of lifetime body mass index trajectories on the incidence and persistence of adult asthma
Impact of lifetime body mass index trajectories on the incidence and persistence of adult asthma
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More than meets the eye
More than meets the eye
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Asthma management in low and middle income countries: case for change
Asthma management in low and middle income countries: case for change
AbstractAsthma is the most common noncommunicable disease in children, and among the most common in adults. The great majo...
A polygenic risk score and age of diagnosis of COPD
A polygenic risk score and age of diagnosis of COPD
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