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Investigating frank autism: clinician initial impressions and autism characteristics
Investigating frank autism: clinician initial impressions and autism characteristics
“Frank autism,” recognizable through the first minutes of an interaction, describes a behavioral presentation ...
Auditory N1 event-related potential amplitude is predictive of serum concentration of BPN14770 in fragile X syndrome
Auditory N1 event-related potential amplitude is predictive of serum concentration of BPN14770 in fragile X syndrome
Fragile X syndrome (FXS) is a rare neurodevelopmental disorder caused by a CGG repeat expansion ≥ 200 re...
Superior temporal sulcus folding, functional network connectivity, and autistic-like traits in a non-clinical population
Superior temporal sulcus folding, functional network connectivity, and autistic-like traits in a non-clinical population
Autistic-like traits (ALT) are prevalent across the general population and might be linked to some facets of a broader aut...
Structure-function coupling in white matter uncovers the hypoconnectivity in autism spectrum disorder
Structure-function coupling in white matter uncovers the hypoconnectivity in autism spectrum disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder associated with alterations in structural and functional c...
Identifying SETBP1 haploinsufficiency molecular pathways to improve patient diagnosis using induced pluripotent stem cells and neural disease modelling
Identifying SETBP1 haploinsufficiency molecular pathways to improve patient diagnosis using induced pluripotent stem cells and neural disease modelling
SETBP1 Haploinsufficiency Disorder (SETBP1-HD) is characterised by mild to moderate intellectual disability, speech and la...
Phenome-wide profiling identifies genotype-phenotype associations in Phelan-McDermid syndrome using family-sourced data from an international registry
Phenome-wide profiling identifies genotype-phenotype associations in Phelan-McDermid syndrome using family-sourced data from an international registry
Phelan-McDermid syndrome (PMS) is a rare neurodevelopmental disorder caused by 22q13 deletions that include the SHANK3 gen...
Pharmacological inhibition of the CB1 cannabinoid receptor restores abnormal brain mitochondrial CB1 receptor expression and rescues bioenergetic and cognitive defects in a female mouse model of Rett syndrome
Pharmacological inhibition of the CB1 cannabinoid receptor restores abnormal brain mitochondrial CB1 receptor expression and rescues bioenergetic and cognitive defects in a female mouse model of Rett syndrome
Defective mitochondria and aberrant brain mitochondrial bioenergetics are consistent features in syndromic intellectual di...
Contracted functional connectivity profiles in autism
Contracted functional connectivity profiles in autism
Autism spectrum disorder (ASD) is a neurodevelopmental condition that is associated with atypical brain network organizati...
Task-based functional neural correlates of social cognition across autism and schizophrenia spectrum disorders
Task-based functional neural correlates of social cognition across autism and schizophrenia spectrum disorders
Autism and schizophrenia spectrum disorders (SSDs) both feature atypical social cognition. Despite evidence for comparable...
Mapping neural correlates of biological motion perception in autistic children using high-density diffuse optical tomography
Mapping neural correlates of biological motion perception in autistic children using high-density diffuse optical tomography
Autism spectrum disorder (ASD), a neurodevelopmental disorder defined by social communication deficits plus repetitive beh...
Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
Previous research on autism spectrum disorders (ASD) have showed important volumetric alterations in the cerebellum and br...
Spontaneous instrumental approach-avoidance learning in social contexts in autism
Spontaneous instrumental approach-avoidance learning in social contexts in autism
Individuals with Autism Spectrum Condition (ASC) are characterized by atypicalities in social interactions, compared to Ty...
1H-NMR-based metabolomics reveals metabolic alterations in early development of a mouse model of Angelman syndrome
1H-NMR-based metabolomics reveals metabolic alterations in early development of a mouse model of Angelman syndrome
Angelman syndrome (AS) is a rare neurodevelopmental genetic disorder caused by the loss of function of the ubiquitin ligas...
Mate selection and current trends in the prevalence of autism
Mate selection and current trends in the prevalence of autism
According to the most recent U.S. CDC surveillance data, the rise in prevalence of childhood autism spectrum disorder amon...
Enhanced interest in letters and numbers in autistic children
Enhanced interest in letters and numbers in autistic children
An intense and precocious interest in written material, together with a discrepancy between decoding and reading comprehen...
Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder
Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder
Mutations in the X-linked gene cyclin-dependent kinase-like 5 (CDKL5) cause a severe neurological disorder characterised b...
Phenotypic and ancestry-related assortative mating in autism
Phenotypic and ancestry-related assortative mating in autism
Positive assortative mating (AM) in several neuropsychiatric traits, including autism, has been noted. However, it is unkn...
Discrimination sensitivity of visual shapes sharpens in autistic adults but only after explicit category learning
Discrimination sensitivity of visual shapes sharpens in autistic adults but only after explicit category learning
Categorization and its influence on perceptual discrimination are essential processes to organize information efficiently....
Embryonic origin of two ASD subtypes of social symptom severity: the larger the brain cortical organoid size, the more severe the social symptoms
Embryonic origin of two ASD subtypes of social symptom severity: the larger the brain cortical organoid size, the more severe the social symptoms
Social affective and communication symptoms are central to autism spectrum disorder (ASD), yet their severity differs acro...
Prospective association of the infant gut microbiome with social behaviors in the ECHO consortium
Prospective association of the infant gut microbiome with social behaviors in the ECHO consortium
Identifying modifiable risk factors of autism spectrum disorders (ASDs) may inform interventions to reduce financial burde...
Moral foundations in autistic people and people with systemizing minds
Moral foundations in autistic people and people with systemizing minds
Do autistic people share the same moral foundations as typical people? Here we built on two prominent theories in psycholo...
The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives
The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives
Most children with Autism Spectrum Disorder (ASD) have co-occurring language impairments and some of these autism-specific...
Trajectory of depressive symptoms over adolescence in autistic and neurotypical youth
Trajectory of depressive symptoms over adolescence in autistic and neurotypical youth
Adolescence coincides with a dramatic rise in the onset of psychiatric conditions including depression. Depression symptom...
Additive interaction between birth asphyxia and febrile seizures on autism spectrum disorder: a population-based study
Additive interaction between birth asphyxia and febrile seizures on autism spectrum disorder: a population-based study
Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental disorder that can significantly impact an individual̵...
Neuroligin-2 shapes individual slow waves during slow-wave sleep and the response to sleep deprivation in mice
Neuroligin-2 shapes individual slow waves during slow-wave sleep and the response to sleep deprivation in mice
Sleep disturbances are a common comorbidity to most neurodevelopmental disorders and tend to worsen disease symptomatology...
Systematic review and meta-analysis: multimodal functional and anatomical neural alterations in autism spectrum disorder
Systematic review and meta-analysis: multimodal functional and anatomical neural alterations in autism spectrum disorder
This meta-analysis aimed to explore the most robust findings across numerous existing resting-state functional imaging and...
Clinical correlates of diagnostic certainty in children and youths with Autistic Disorder
Clinical correlates of diagnostic certainty in children and youths with Autistic Disorder
Clinicians diagnosing autism rely on diagnostic criteria and instruments in combination with an implicit knowledge based o...
Shank3 deficiency elicits autistic-like behaviors by activating p38α in hypothalamic AgRP neurons
Shank3 deficiency elicits autistic-like behaviors by activating p38α in hypothalamic AgRP neurons
SH3 and multiple ankyrin repeat domains protein 3 (SHANK3) monogenic mutations or deficiency leads to excessive stereotypi...
Detection of autism spectrum disorder-related pathogenic trio variants by a novel structure-based approach
Detection of autism spectrum disorder-related pathogenic trio variants by a novel structure-based approach
Glutamatergic synapse dysfunction is believed to underlie the development of Autism Spectrum Disorder (ASD) and Intellectu...
Granulocyte macrophage colony-stimulating factor-induced macrophages of individuals with autism spectrum disorder adversely affect neuronal dendrites through the secretion of pro-inflammatory cytokines
Granulocyte macrophage colony-stimulating factor-induced macrophages of individuals with autism spectrum disorder adversely affect neuronal dendrites through the secretion of pro-inflammatory cytokines
A growing body of evidence suggests that immune dysfunction and inflammation in the peripheral tissues as well as the cent...
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