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MiRNA-383 AND MiRNA-384 SUPPRESS PROOPIOMELANOCORTIN GENE EXPRESSION IN THE HYPOTHALAMUS: EFFECTS OF EARLY LIFE ETHANOL EXPOSURE
MiRNA-383 AND MiRNA-384 SUPPRESS PROOPIOMELANOCORTIN GENE EXPRESSION IN THE HYPOTHALAMUS: EFFECTS OF EARLY LIFE ETHANOL EXPOSURE
Introduction: Early life ethanol exposure is known to program hypothalamic proopiomelanocortin (POMC) neurons to express a...
Second primary malignancies in patients with a neuroendocrine neoplasm in England
Second primary malignancies in patients with a neuroendocrine neoplasm in England
Introduction Patients with neuroendocrine neoplasms (NENs) may often develop other malignancies. This study aimed to ident...
Changes in corticotropin releasing factor receptor type 1, co-expression with tyrosine hydroxylase and oxytocin neurons, and anxiety-like behaviors across the postpartum period in mice
Changes in corticotropin releasing factor receptor type 1, co-expression with tyrosine hydroxylase and oxytocin neurons, and anxiety-like behaviors across the postpartum period in mice
Introduction: Corticotropin-releasing factor (CRF) and its primary receptor (CRFR1) are critical regulators of behavioral ...
Chromosome 18 loss of heterozygosity in small intestinal neuroendocrine tumours: Multi-omic and tumour composition analyses
Chromosome 18 loss of heterozygosity in small intestinal neuroendocrine tumours: Multi-omic and tumour composition analyses
Background: Small intestinal neuroendocrine tumours (siNETs) are rare neoplasms which present with low mutational burden a...
Identification of the immune subtypes for the prediction of metastasis in pancreatic neuroendocrine tumors
Identification of the immune subtypes for the prediction of metastasis in pancreatic neuroendocrine tumors
Introduction: Most patients with pancreatic neuroendocrine tumors (pNETs) present with unresectable or metastatic disease....
SILIBININ, AN HSP90 INHIBITOR, ON HUMAN ACTH-SECRETING ADENOMAS
SILIBININ, AN HSP90 INHIBITOR, ON HUMAN ACTH-SECRETING ADENOMAS
Introduction. The glucocorticoid receptor is pivotal to control corticotrophin (ACTH) secretion and its function is closel...
Endogenous sex hormones modulate the analgesic effect of tramadol in lean and high fat diet-induced obese Wistar rats: a preclinical molecular approach
Endogenous sex hormones modulate the analgesic effect of tramadol in lean and high fat diet-induced obese Wistar rats: a preclinical molecular approach
Introduction: Differences in pain thresholds may have implications in pain management, as they may account in part for the...
SIN3A defects associated with syndromic congenital hypogonadotropic hypogonadism: an overlap with Witteveen-Kolk syndrome
SIN3A defects associated with syndromic congenital hypogonadotropic hypogonadism: an overlap with Witteveen-Kolk syndrome
Introduction: Congenital hypogonadotropic hypogonadism (CHH) is a rare condition caused by GnRH deficiency. More than 40 g...
5-Iodotubercidin Inhibits the Growth of Insulinoma Cells by Inducing Apoptosis
5-Iodotubercidin Inhibits the Growth of Insulinoma Cells by Inducing Apoptosis
Background/Aims: 5-Iodotubercidin, a type of purine derivative, has attracted increasingly attention in tumor chemotherapy...
Author Index Vol. 113, No. 2, 2023
Author Index Vol. 113, No. 2, 2023
Neuroendocri...
Subject Index Vol. 113, No. 2, 2023
Subject Index Vol. 113, No. 2, 2023
Neuroendocri...
ERα stimulation rapidly modulates excitatory synapse properties in female rat nucleus accumbens core
ERα stimulation rapidly modulates excitatory synapse properties in female rat nucleus accumbens core
Introduction: The nucleus accumbens core (NAcc) is a sexually differentiated brain region that is modulated by steroid hor...
Diagnosis and Management of Idiopathic Hypothalamic Dysfunction: A Case Series and Systematic Review
Diagnosis and Management of Idiopathic Hypothalamic Dysfunction: A Case Series and Systematic Review
Introduction Idiopathic hypothalamic dysfunction (IHD) is a rare syndrome with heterogeneous clinical symptoms. This study...
Ultrastructural and molecular evidence of macroautophagy in functioning PitNETs and experimental pituitary tumors
Ultrastructural and molecular evidence of macroautophagy in functioning PitNETs and experimental pituitary tumors
Introduction: Macroautophagy is a lysosome-mediated degradation process that controls the quality of cytoplasmic component...
Paraventricular Nucleus of the Hypothalamus Oxytocin and Incubation of Heroin Seeking
Paraventricular Nucleus of the Hypothalamus Oxytocin and Incubation of Heroin Seeking
Introduction: There are numerous pharmacologic treatments for opioid use disorder (OUD), but none that directly target the...
Increased Lactobacillus Abundance Contributes to Stress Resilience in Mice Exposed to Chronic Social Defeat Stress
Increased Lactobacillus Abundance Contributes to Stress Resilience in Mice Exposed to Chronic Social Defeat Stress
<b><i>Introduction:</i></b> Accumulating evidence indicates that abnormalities in the composition ...
Genetic study in pheochromocytoma ¿is it possible to stratify the risk of hereditary pheochromocytoma?
Genetic study in pheochromocytoma ¿is it possible to stratify the risk of hereditary pheochromocytoma?
Introduction: It is estimated that 30-40% of patients with apparently sporadic pheochromocytomas (PHEOs) have an inherited...
Post-traumatic hypopituitarism - a neglected consequence of traumatic brain injury.
Post-traumatic hypopituitarism - a neglected consequence of traumatic brain injury.
Post-traumatic hypopituitarism (PTHP), described for the first time in 1918, used to be neglected and only considered a ra...
A PROSPECTIVE ANALYSIS OF THE METYRAPONE SHORT TEST USING TARGETED AND UNTARGETED METABOLOMICS
A PROSPECTIVE ANALYSIS OF THE METYRAPONE SHORT TEST USING TARGETED AND UNTARGETED METABOLOMICS
Introduction The present study aimed to prove the metyrapone short test in a day clinic to be suitable for examining the i...
Segmental Abnormalities of White Matter Microstructure in Primary Hypothyroidism Identified by Automated Fiber Quantification
Segmental Abnormalities of White Matter Microstructure in Primary Hypothyroidism Identified by Automated Fiber Quantification
Introduction: Hypothyroidism leads to impaired white matter (WM) integrity, associated with cognitive/neuropsychiatric dys...
Alterations of spontaneous cortical and subcortical activity in type 2 diabetes mellitus with and without depression
Alterations of spontaneous cortical and subcortical activity in type 2 diabetes mellitus with and without depression
Introduction: Type 2 diabetes mellitus (T2DM) patients with depression have a higher risk of complications and mortality t...
Potential of Ascorbic Acid supplements to Ameliorate the Deleterious Effects of Hyperuricemia on Albino Wistar Rats’ Hippocampus (Structural and Functional study)
Potential of Ascorbic Acid supplements to Ameliorate the Deleterious Effects of Hyperuricemia on Albino Wistar Rats’ Hippocampus (Structural and Functional study)
Introduction: Diet rich in purines may increase the serum level of uric acid causing hyperuricemia contributing learning a...
TSAb Modulates Microglia M1 Polarization via Activation of the TSHR-Mediated NF-κB Signaling Pathway
TSAb Modulates Microglia M1 Polarization via Activation of the TSHR-Mediated NF-κB Signaling Pathway
<b><i>Introduction:</i></b> Thyrotropin receptor-stimulating antibody (TSAb) is a pathogenic antib...
Increased Lactobacillus abundance contributes to stress resilience in mice exposed to chronic social defeat stress
Increased Lactobacillus abundance contributes to stress resilience in mice exposed to chronic social defeat stress
Introduction: Accumulating evidence indicates that abnormalities in the composition of gastrointestinal (GI) microbiota pl...
Obesity-induced memory deficits in female rats are oestrous cycle-dependent and linked to impaired brain kynurenine pathway metabolism
Obesity-induced memory deficits in female rats are oestrous cycle-dependent and linked to impaired brain kynurenine pathway metabolism
Introduction: Obesity is associated with impaired learning, but the mechanisms underlying this cognitive dysfunction are p...
Blockade of ghrelin receptor signaling enhances conditioned passive avoidance and context-associated cFos activation in fasted male rats
Blockade of ghrelin receptor signaling enhances conditioned passive avoidance and context-associated cFos activation in fasted male rats
Interoceptive feedback to the brain regarding the body’s physiological state plays an important role in guiding motivated ...
Adolescence predatory risk alters social behaviors and cognitive ability and central oxytocin and vasopressin expression in adult Brandt’s voles
Adolescence predatory risk alters social behaviors and cognitive ability and central oxytocin and vasopressin expression in adult Brandt’s voles
Introduction: Stress during adolescence causes long-term behavioral changes in adulthood. We previously found that adolesc...
Persistent organic pollutant exposure and thyroid function among 12-year-old children
Persistent organic pollutant exposure and thyroid function among 12-year-old children
Introduction Polychlorobiphenyls (PCBs), organochlorine pesticides (OCPs) and per- and polyfluoroalkyl substances (PFASs) ...
Increased expression levels of soluble fms-like tyrosine kinase-1 inhibits the development of the nervous system
Increased expression levels of soluble fms-like tyrosine kinase-1 inhibits the development of the nervous system
Introduction: Preeclampsia (PE) remains a leading cause of maternal and perinatal morbidity. At present, only limited opti...
Cancer associated fibroblasts induce proliferation and therapeutic resistance to everolimus in neuroendocrine tumors through STAT3 activation
Cancer associated fibroblasts induce proliferation and therapeutic resistance to everolimus in neuroendocrine tumors through STAT3 activation
Introduction Cancer-associated fibroblasts (CAF) have been identified as relevant contributors to cancer progression and d...
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